Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 130023561 . G A CCDS5820.1:NM_001868.2:c.622Gcc>Acc_NP_001859.1:p.208A>T Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5om9 1 P15085 100.0 0.0 X-RAY
2017-08-09 ALA A:208 A:98 42.0 0.365 H -61.8 -32.0 42.0 0.365 0.0 HOH
2.594
O
O
ALA B:208 B:98 45.0 0.391 H -59.3 -37.6 45.0 0.391 0.0 HOH
2.731
O
O
4uf4 1 P15085 99.76 0.0 X-RAY
2016-01-20 ALA A:208 A:208 42.0 0.365 H -59.3 -33.4 42.0 0.365 0.0 HOH
2.576
O
O
ALA B:208 B:208 45.0 0.391 H -59.0 -37.7 NA NA NA
1pca 1 P09954 81.55 0.0 X-RAY
1993-10-31 ALA A:193 A:98 42.0 0.365 H -66.1 -25.2 42.0 0.365 0.0 HOH
2.590
O
O
2v77 1 P15085 100.0 0.0 X-RAY
2008-07-01 ALA A:98 A:98 47.0 0.409 H -62.2 -43.8 47.0 0.409 0.0 HOH
2.647
O
O
ALA B:98 B:98 56.0 0.487 H -64.2 -39.4 NA NA NA
4uee 1 P15085 100.0 0.0 X-RAY
2016-01-20 ALA A:98 A:98 46.0 0.4 H -61.3 -45.6 46.0 0.4 0.0 HOH
2.932
O
O
ALA B:98 B:98 44.0 0.383 H -57.0 -40.4 44.0 0.383 0.0 HOH
6.238
N
O
4uef 1 P15085 100.0 0.0 X-RAY
2016-01-20 ALA A:98 A:208 50.0 0.435 H -64.1 -39.9 50.0 0.435 0.0 HOH
2.682
O
O
ALA B:98 B:208 44.0 0.383 H -61.4 -40.7 NA NA NA
4uez 1 P15085 100.0 0.0 X-RAY
2016-01-20 ALA A:98 A:208 48.0 0.417 H -69.0 -37.5 48.0 0.417 0.0 HOH
3.749
N
O
ALA B:98 B:208 46.0 0.4 H -65.7 -36.9 NA NA NA
6i6z 1 P15085 100.0 0.0 X-RAY
2018-12-12 ALA A:98 A:208 49.0 0.426 H -65.5 -37.5 49.0 0.426 0.0 HOH
2.639
O
O
ALA B:98 B:208 42.0 0.365 H -61.9 -40.4 42.0 0.365 0.0 HOH
2.558
O
O
3fju 1 P15085 100.0 0.0 X-RAY
2008-12-30 ALA A:97 A:98 46.0 0.4 H -60.1 -37.7 46.0 0.4 0.0 HOH
2.672
O
O
1pyt 2 P00730 81.23 0.0 X-RAY
1997-01-27 ALA B:98 B:98 44.0 0.383 T -63.0 -26.3 44.0 0.383 0.0 HOH
4.677
CB
O
3kgq 1 P00730 81.23 0.0 X-RAY
2010-10-27 ALA A:98 A:98 41.0 0.357 H -58.5 -40.1 41.0 0.357 0.0 HOH
2.681
O
O
1arm 1 P00730 80.91 0.0 X-RAY
1996-08-17 ALA A:98 A:98 51.0 0.443 H -62.2 -35.4 51.0 0.443 0.0 HOH
2.624
O
O
1ee3 1 P00730 80.91 0.0 X-RAY
2002-06-26 ALA A:98 P:98 53.0 0.461 H -64.0 -39.2 53.0 0.461 0.0 HOH
2.638
O
O
1ell 1 P00730 80.91 0.0 X-RAY
2002-06-26 ALA A:98 P:98 53.0 0.461 H -60.2 -40.6 53.0 0.461 0.0 HOH
2.629
O
O
1elm 1 P00730 80.91 0.0 X-RAY
2002-06-26 ALA A:98 P:98 53.0 0.461 H -65.0 -36.0 53.0 0.461 0.0 HOH
2.601
O
O
1yme 1 P00730 80.91 0.0 X-RAY
1997-02-12 ALA A:98 A:98 51.0 0.443 H -58.3 -41.2 51.0 0.443 0.0 HOH
2.699
O
O
1zlh 1 P00730 80.91 0.0 X-RAY
2005-07-05 ALA A:98 A:98 49.0 0.426 H -64.7 -38.2 49.0 0.426 0.0 HOH
2.683
O
O
2abz 1 P00730 80.91 0.0 X-RAY
2006-01-31 ALA A:98 A:98 52.0 0.452 H -62.6 -41.7 52.0 0.452 0.0
ALA B:98 B:98 48.0 0.417 H -54.5 -49.6 48.0 0.417 0.0
3hlp 1 A6H6Y4 80.91 0.0 X-RAY
2010-06-02 ALA A:98 A:98 58.0 0.504 H -59.7 -40.0 58.0 0.504 0.0 HOH
2.546
O
O
ALA B:98 B:98 51.0 0.443 H -62.9 -38.5 NA NA NA
3huv 1 A6H6Y4 80.91 0.0 X-RAY
2010-06-02 ALA A:98 A:98 50.0 0.435 H -58.1 -46.3 50.0 0.435 0.0 HOH
2.670
O
O
3i1u 1 A6H6Y4 80.91 0.0 X-RAY
2009-11-17 ALA A:98 A:98 52.0 0.452 H -60.1 -40.0 52.0 0.452 0.0 HOH
2.642
O
O
1hdq 1 P00730 81.43 0.0 X-RAY
2001-11-15 ALA A:98 A:98 47.0 0.409 H -63.6 -34.1 47.0 0.409 0.0 HOH
2.592
O
O
2ctb 1 P00730 81.43 0.0 X-RAY
1994-01-31 ALA A:98 A:98 45.0 0.391 H -59.2 -40.3 45.0 0.391 0.0 HOH
2.614
O
O
2ctc 1 P00730 81.43 0.0 X-RAY
1994-01-31 ALA A:98 A:98 47.0 0.409 H -61.5 -35.2 47.0 0.409 0.0 HOH
2.657
O
O
1arl 1 P00730 81.11 0.0 X-RAY
1996-08-01 ALA A:98 A:98 53.0 0.461 H -62.7 -37.2 53.0 0.461 0.0 HOH
2.610
O
O
1cpx 1 P00730 81.11 0.0 X-RAY
1998-08-05 ALA A:98 A:98 55.0 0.478 H -68.1 -35.0 55.0 0.478 0.0 HOH
2.572
O
O
1f57 1 P00730 81.11 0.0 X-RAY
2000-09-06 ALA A:98 A:98 50.0 0.435 H -64.9 -35.3 50.0 0.435 0.0 HOH
2.628
O
O
1m4l 1 P00730 81.11 0.0 X-RAY
2003-01-10 ALA A:98 A:98 54.0 0.47 H -63.1 -34.7 54.0 0.47 0.0 HOH
2.543
O
O
2rfh 1 A6H6Y4 81.11 0.0 X-RAY
2008-04-22 ALA A:98 A:98 50.0 0.435 H -64.5 -39.8 50.0 0.435 0.0 HOH
2.913
O
O
3fvl 1 P00730 81.11 0.0 X-RAY
2010-01-12 ALA A:98 A:98 53.0 0.461 H -64.1 -41.1 53.0 0.461 0.0 HOH
2.645
O
O
ALA B:98 C:98 51.0 0.443 H -61.3 -38.6 51.0 0.443 0.0 HOH
3.467
N
O
ALA C:98 E:98 53.0 0.461 H -62.2 -38.1 53.0 0.461 0.0 HOH
2.562
O
O
3fx6 1 P00730 81.11 0.0 X-RAY
2009-08-25 ALA A:98 A:98 53.0 0.461 H -64.9 -40.7 53.0 0.461 0.0 HOH
2.650
O
O
ALA B:98 C:98 49.0 0.426 H -62.4 -38.5 49.0 0.426 0.0 HOH
3.511
N
O
ALA C:98 E:98 53.0 0.461 H -61.8 -39.0 53.0 0.461 0.0 HOH
2.587
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15085-f1 1 P15085 100.0 0.0 ALA A:208 A:208 41.0 0.357 H -61.3 -34.5