Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 130023561 | . | G | A | CCDS5820.1:NM_001868.2:c.622Gcc>Acc_NP_001859.1:p.208A>T | Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5om9 | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2017-08-09 | ALA | A:208 | A:98 | 42.0 | 0.365 | H | -61.8 | -32.0 | 42.0 | 0.365 | 0.0 |
HOH |
2.594 |
O |
O |
||
ALA | B:208 | B:98 | 45.0 | 0.391 | H | -59.3 | -37.6 | 45.0 | 0.391 | 0.0 |
HOH |
2.731 |
O |
O |
|||||||||
4uf4 | 1 | P15085 | 99.76 | 0.0 |
X-RAY |
2016-01-20 | ALA | A:208 | A:208 | 42.0 | 0.365 | H | -59.3 | -33.4 | 42.0 | 0.365 | 0.0 |
HOH |
2.576 |
O |
O |
||
ALA | B:208 | B:208 | 45.0 | 0.391 | H | -59.0 | -37.7 | NA | NA | NA | |||||||||||||
1pca | 1 | P09954 | 81.55 | 0.0 |
X-RAY |
1993-10-31 | ALA | A:193 | A:98 | 42.0 | 0.365 | H | -66.1 | -25.2 | 42.0 | 0.365 | 0.0 |
HOH |
2.590 |
O |
O |
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2v77 | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2008-07-01 | ALA | A:98 | A:98 | 47.0 | 0.409 | H | -62.2 | -43.8 | 47.0 | 0.409 | 0.0 |
HOH |
2.647 |
O |
O |
||
ALA | B:98 | B:98 | 56.0 | 0.487 | H | -64.2 | -39.4 | NA | NA | NA | |||||||||||||
4uee | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2016-01-20 | ALA | A:98 | A:98 | 46.0 | 0.4 | H | -61.3 | -45.6 | 46.0 | 0.4 | 0.0 |
HOH |
2.932 |
O |
O |
||
ALA | B:98 | B:98 | 44.0 | 0.383 | H | -57.0 | -40.4 | 44.0 | 0.383 | 0.0 |
HOH |
6.238 |
N |
O |
|||||||||
4uef | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2016-01-20 | ALA | A:98 | A:208 | 50.0 | 0.435 | H | -64.1 | -39.9 | 50.0 | 0.435 | 0.0 |
HOH |
2.682 |
O |
O |
||
ALA | B:98 | B:208 | 44.0 | 0.383 | H | -61.4 | -40.7 | NA | NA | NA | |||||||||||||
4uez | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2016-01-20 | ALA | A:98 | A:208 | 48.0 | 0.417 | H | -69.0 | -37.5 | 48.0 | 0.417 | 0.0 |
HOH |
3.749 |
N |
O |
||
ALA | B:98 | B:208 | 46.0 | 0.4 | H | -65.7 | -36.9 | NA | NA | NA | |||||||||||||
6i6z | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2018-12-12 | ALA | A:98 | A:208 | 49.0 | 0.426 | H | -65.5 | -37.5 | 49.0 | 0.426 | 0.0 |
HOH |
2.639 |
O |
O |
||
ALA | B:98 | B:208 | 42.0 | 0.365 | H | -61.9 | -40.4 | 42.0 | 0.365 | 0.0 |
HOH |
2.558 |
O |
O |
|||||||||
3fju | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2008-12-30 | ALA | A:97 | A:98 | 46.0 | 0.4 | H | -60.1 | -37.7 | 46.0 | 0.4 | 0.0 |
HOH |
2.672 |
O |
O |
||
1pyt | 2 | P00730 | 81.23 | 0.0 |
X-RAY |
1997-01-27 | ALA | B:98 | B:98 | 44.0 | 0.383 | T | -63.0 | -26.3 | 44.0 | 0.383 | 0.0 |
HOH |
4.677 |
CB |
O |
||
3kgq | 1 | P00730 | 81.23 | 0.0 |
X-RAY |
2010-10-27 | ALA | A:98 | A:98 | 41.0 | 0.357 | H | -58.5 | -40.1 | 41.0 | 0.357 | 0.0 |
HOH |
2.681 |
O |
O |
||
1arm | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
1996-08-17 | ALA | A:98 | A:98 | 51.0 | 0.443 | H | -62.2 | -35.4 | 51.0 | 0.443 | 0.0 |
HOH |
2.624 |
O |
O |
||
1ee3 | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
2002-06-26 | ALA | A:98 | P:98 | 53.0 | 0.461 | H | -64.0 | -39.2 | 53.0 | 0.461 | 0.0 |
HOH |
2.638 |
O |
O |
||
1ell | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
2002-06-26 | ALA | A:98 | P:98 | 53.0 | 0.461 | H | -60.2 | -40.6 | 53.0 | 0.461 | 0.0 |
HOH |
2.629 |
O |
O |
||
1elm | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
2002-06-26 | ALA | A:98 | P:98 | 53.0 | 0.461 | H | -65.0 | -36.0 | 53.0 | 0.461 | 0.0 |
HOH |
2.601 |
O |
O |
||
1yme | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
1997-02-12 | ALA | A:98 | A:98 | 51.0 | 0.443 | H | -58.3 | -41.2 | 51.0 | 0.443 | 0.0 |
HOH |
2.699 |
O |
O |
||
1zlh | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
2005-07-05 | ALA | A:98 | A:98 | 49.0 | 0.426 | H | -64.7 | -38.2 | 49.0 | 0.426 | 0.0 |
HOH |
2.683 |
O |
O |
||
2abz | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
2006-01-31 | ALA | A:98 | A:98 | 52.0 | 0.452 | H | -62.6 | -41.7 | 52.0 | 0.452 | 0.0 | ||||||
ALA | B:98 | B:98 | 48.0 | 0.417 | H | -54.5 | -49.6 | 48.0 | 0.417 | 0.0 | |||||||||||||
3hlp | 1 | A6H6Y4 | 80.91 | 0.0 |
X-RAY |
2010-06-02 | ALA | A:98 | A:98 | 58.0 | 0.504 | H | -59.7 | -40.0 | 58.0 | 0.504 | 0.0 |
HOH |
2.546 |
O |
O |
||
ALA | B:98 | B:98 | 51.0 | 0.443 | H | -62.9 | -38.5 | NA | NA | NA | |||||||||||||
3huv | 1 | A6H6Y4 | 80.91 | 0.0 |
X-RAY |
2010-06-02 | ALA | A:98 | A:98 | 50.0 | 0.435 | H | -58.1 | -46.3 | 50.0 | 0.435 | 0.0 |
HOH |
2.670 |
O |
O |
||
3i1u | 1 | A6H6Y4 | 80.91 | 0.0 |
X-RAY |
2009-11-17 | ALA | A:98 | A:98 | 52.0 | 0.452 | H | -60.1 | -40.0 | 52.0 | 0.452 | 0.0 |
HOH |
2.642 |
O |
O |
||
1hdq | 1 | P00730 | 81.43 | 0.0 |
X-RAY |
2001-11-15 | ALA | A:98 | A:98 | 47.0 | 0.409 | H | -63.6 | -34.1 | 47.0 | 0.409 | 0.0 |
HOH |
2.592 |
O |
O |
||
2ctb | 1 | P00730 | 81.43 | 0.0 |
X-RAY |
1994-01-31 | ALA | A:98 | A:98 | 45.0 | 0.391 | H | -59.2 | -40.3 | 45.0 | 0.391 | 0.0 |
HOH |
2.614 |
O |
O |
||
2ctc | 1 | P00730 | 81.43 | 0.0 |
X-RAY |
1994-01-31 | ALA | A:98 | A:98 | 47.0 | 0.409 | H | -61.5 | -35.2 | 47.0 | 0.409 | 0.0 |
HOH |
2.657 |
O |
O |
||
1arl | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
1996-08-01 | ALA | A:98 | A:98 | 53.0 | 0.461 | H | -62.7 | -37.2 | 53.0 | 0.461 | 0.0 |
HOH |
2.610 |
O |
O |
||
1cpx | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
1998-08-05 | ALA | A:98 | A:98 | 55.0 | 0.478 | H | -68.1 | -35.0 | 55.0 | 0.478 | 0.0 |
HOH |
2.572 |
O |
O |
||
1f57 | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
2000-09-06 | ALA | A:98 | A:98 | 50.0 | 0.435 | H | -64.9 | -35.3 | 50.0 | 0.435 | 0.0 |
HOH |
2.628 |
O |
O |
||
1m4l | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
2003-01-10 | ALA | A:98 | A:98 | 54.0 | 0.47 | H | -63.1 | -34.7 | 54.0 | 0.47 | 0.0 |
HOH |
2.543 |
O |
O |
||
2rfh | 1 | A6H6Y4 | 81.11 | 0.0 |
X-RAY |
2008-04-22 | ALA | A:98 | A:98 | 50.0 | 0.435 | H | -64.5 | -39.8 | 50.0 | 0.435 | 0.0 |
HOH |
2.913 |
O |
O |
||
3fvl | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
2010-01-12 | ALA | A:98 | A:98 | 53.0 | 0.461 | H | -64.1 | -41.1 | 53.0 | 0.461 | 0.0 |
HOH |
2.645 |
O |
O |
||
ALA | B:98 | C:98 | 51.0 | 0.443 | H | -61.3 | -38.6 | 51.0 | 0.443 | 0.0 |
HOH |
3.467 |
N |
O |
|||||||||
ALA | C:98 | E:98 | 53.0 | 0.461 | H | -62.2 | -38.1 | 53.0 | 0.461 | 0.0 |
HOH |
2.562 |
O |
O |
|||||||||
3fx6 | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
2009-08-25 | ALA | A:98 | A:98 | 53.0 | 0.461 | H | -64.9 | -40.7 | 53.0 | 0.461 | 0.0 |
HOH |
2.650 |
O |
O |
||
ALA | B:98 | C:98 | 49.0 | 0.426 | H | -62.4 | -38.5 | 49.0 | 0.426 | 0.0 |
HOH |
3.511 |
N |
O |
|||||||||
ALA | C:98 | E:98 | 53.0 | 0.461 | H | -61.8 | -39.0 | 53.0 | 0.461 | 0.0 |
HOH |
2.587 |
O |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p15085-f1 | 1 | P15085 | 100.0 | 0.0 | ALA | A:208 | A:208 | 41.0 | 0.357 | H | -61.3 | -34.5 |