Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 130023597 . G A CCDS5820.1:NM_001868.2:c.658Gtc>Atc_NP_001859.1:p.220V>I Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5om9 1 P15085 100.0 0.0 X-RAY
 2017-08-09 VAL A:220 A:110 3.0 0.019 -114.3 94.8 3.0 0.019 0.0 HOH
 2.747
 N
 O
VAL B:220 B:110 4.0 0.026 -118.9 91.9 4.0 0.026 0.0 HOH
 2.950
 N
 O
4uf4 1 P15085 99.76 0.0 X-RAY
 2016-01-20 VAL A:220 A:220 4.0 0.026 -112.0 95.1 4.0 0.026 0.0 HOH
 2.766
 O
 O
VAL B:220 B:220 3.0 0.019 -117.8 89.9 NA NA NA
1pca 1 P09954 81.55 0.0 X-RAY
 1993-10-31 VAL A:205 A:110 3.0 0.019 -112.2 85.3 3.0 0.019 0.0 HOH
 2.820
 O
 O
2v77 1 P15085 100.0 0.0 X-RAY
 2008-07-01 VAL A:110 A:110 4.0 0.026 -118.0 89.8 4.0 0.026 0.0 HOH
 2.817
 O
 O
VAL B:110 B:110 4.0 0.026 -115.0 88.4 NA NA NA
4uee 1 P15085 100.0 0.0 X-RAY
 2016-01-20 VAL A:110 A:110 3.0 0.019 -110.0 92.6 3.0 0.019 0.0 HOH
 2.745
 N
 O
VAL B:110 B:110 3.0 0.019 -114.0 93.7 3.0 0.019 0.0 HOH
 2.787
 O
 O
4uef 1 P15085 100.0 0.0 X-RAY
 2016-01-20 VAL A:110 A:220 4.0 0.026 -116.9 88.4 4.0 0.026 0.0 HOH
 2.865
 O
 O
VAL B:110 B:220 4.0 0.026 -116.0 92.8 NA NA NA
4uez 1 P15085 100.0 0.0 X-RAY
 2016-01-20 VAL A:110 A:220 5.0 0.032 -114.0 91.3 5.0 0.032 0.0 HOH
 2.912
 O
 O
VAL B:110 B:220 5.0 0.032 -119.0 91.6 NA NA NA
6i6z 1 P15085 100.0 0.0 X-RAY
 2018-12-12 VAL A:110 A:220 5.0 0.032 -116.3 89.2 5.0 0.032 0.0 HOH
 2.832
 O
 O
VAL B:110 B:220 4.0 0.026 -116.9 91.7 4.0 0.026 0.0 HOH
 2.888
 O
 O
3fju 1 P15085 100.0 0.0 X-RAY
 2008-12-30 VAL A:109 A:110 5.0 0.032 -115.9 90.9 5.0 0.032 0.0 HOH
 2.799
 O
 O
1pyt 2 P00730 81.23 0.0 X-RAY
 1997-01-27 VAL B:110 B:110 3.0 0.019 -129.1 87.4 3.0 0.019 0.0 HOH
 2.605
 O
 O
3kgq 1 P00730 81.23 0.0 X-RAY
 2010-10-27 VAL A:110 A:110 1.0 0.006 -123.2 87.0 1.0 0.006 0.0 NA
HOH
 8.284
2.717
 CG1
O
 NA
O
1arm 1 P00730 80.91 0.0 X-RAY
 1996-08-17 VAL A:110 A:110 2.0 0.013 -125.3 91.9 2.0 0.013 0.0 HOH
 2.895
 O
 O
1ee3 1 P00730 80.91 0.0 X-RAY
 2002-06-26 VAL A:110 P:110 3.0 0.019 -124.2 87.0 3.0 0.019 0.0 HOH
 2.804
 O
 O
1ell 1 P00730 80.91 0.0 X-RAY
 2002-06-26 VAL A:110 P:110 3.0 0.019 -124.7 86.7 3.0 0.019 0.0 HOH
 2.808
 O
 O
1elm 1 P00730 80.91 0.0 X-RAY
 2002-06-26 VAL A:110 P:110 3.0 0.019 -124.0 87.5 3.0 0.019 0.0 HOH
 2.856
 O
 O
1yme 1 P00730 80.91 0.0 X-RAY
 1997-02-12 VAL A:110 A:110 2.0 0.013 -126.2 91.0 2.0 0.013 0.0 HOH
 2.806
 O
 O
1zlh 1 P00730 80.91 0.0 X-RAY
 2005-07-05 VAL A:110 A:110 2.0 0.013 -129.3 88.8 2.0 0.013 0.0 ZN
HOH
 9.980
2.699
 CG1
O
 ZN
O
2abz 1 P00730 80.91 0.0 X-RAY
 2006-01-31 VAL A:110 A:110 1.0 0.006 -125.3 87.4 1.0 0.006 0.0
VAL B:110 B:110 2.0 0.013 -127.1 91.7 2.0 0.013 0.0
3hlp 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 VAL A:110 A:110 3.0 0.019 -120.3 82.7 3.0 0.019 0.0 HOH
 2.824
 O
 O
VAL B:110 B:110 2.0 0.013 -124.5 85.1 NA NA NA
3huv 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 VAL A:110 A:110 1.0 0.006 -128.6 88.5 1.0 0.006 0.0 HOH
 2.796
 O
 O
3i1u 1 A6H6Y4 80.91 0.0 X-RAY
 2009-11-17 VAL A:110 A:110 2.0 0.013 -125.2 86.3 2.0 0.013 0.0 HOH
 2.794
 O
 O
1hdq 1 P00730 81.43 0.0 X-RAY
 2001-11-15 VAL A:110 A:110 2.0 0.013 -122.5 84.0 2.0 0.013 0.0 HOH
 2.795
 O
 O
2ctb 1 P00730 81.43 0.0 X-RAY
 1994-01-31 VAL A:110 A:110 2.0 0.013 -123.8 88.9 2.0 0.013 0.0 HOH
 2.825
 O
 O
2ctc 1 P00730 81.43 0.0 X-RAY
 1994-01-31 VAL A:110 A:110 2.0 0.013 -126.7 88.1 2.0 0.013 0.0 HOH
 2.808
 O
 O
1arl 1 P00730 81.11 0.0 X-RAY
 1996-08-01 VAL A:110 A:110 2.0 0.013 -125.1 90.7 2.0 0.013 0.0 HOH
 2.747
 N
 O
1cpx 1 P00730 81.11 0.0 X-RAY
 1998-08-05 VAL A:110 A:110 2.0 0.013 -121.0 91.1 2.0 0.013 0.0 HOH
 2.851
 O
 O
1f57 1 P00730 81.11 0.0 X-RAY
 2000-09-06 VAL A:110 A:110 2.0 0.013 -122.4 88.5 2.0 0.013 0.0 HOH
 2.791
 O
 O
1m4l 1 P00730 81.11 0.0 X-RAY
 2003-01-10 VAL A:110 A:110 2.0 0.013 -125.2 87.8 2.0 0.013 0.0 HOH
 2.848
 O
 O
2rfh 1 A6H6Y4 81.11 0.0 X-RAY
 2008-04-22 VAL A:110 A:110 2.0 0.013 -124.1 83.9 2.0 0.013 0.0 HOH
 2.852
 O
 O
3fvl 1 P00730 81.11 0.0 X-RAY
 2010-01-12 VAL A:110 A:110 2.0 0.013 -125.3 85.6 2.0 0.013 0.0 HOH
 2.690
 O
 O
VAL B:110 C:110 2.0 0.013 -126.8 82.5 2.0 0.013 0.0 HOH
 2.750
 O
 O
VAL C:110 E:110 2.0 0.013 -125.0 86.0 2.0 0.013 0.0 HOH
 2.782
 O
 O
3fx6 1 P00730 81.11 0.0 X-RAY
 2009-08-25 VAL A:110 A:110 2.0 0.013 -125.1 86.4 2.0 0.013 0.0 HOH
 2.671
 O
 O
VAL B:110 C:110 2.0 0.013 -127.1 83.5 2.0 0.013 0.0 HOH
 2.726
 O
 O
VAL C:110 E:110 2.0 0.013 -125.7 85.7 2.0 0.013 0.0 HOH
 2.778
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15085-f1 1 P15085 100.0 0.0 VAL A:220 A:220 6.0 0.039 -130.4 84.4