Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 130024448 . C A CCDS5820.1:NM_001868.2:c.768aaC>aaA_NP_001859.1:p.256N>K Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5om9 1 P15085 100.0 0.0 X-RAY
 2017-08-09 ASN A:256 A:146 0.0 0.0 -100.7 9.9 0.0 0.0 0.0 O2S
HOH
 8.951
4.854
 N
O
 O03
O
ASN B:256 B:146 0.0 0.0 -107.6 1.1 0.0 0.0 0.0 O2S
HOH
 8.877
4.927
 N
O
 O01
O
4uf4 1 P15085 99.76 0.0 X-RAY
 2016-01-20 ASN A:256 A:256 0.0 0.0 -99.6 8.8 0.0 0.0 0.0 O2V
HOH
 8.947
4.872
 N
O
 O03
O
ASN B:256 B:256 0.0 0.0 -107.3 1.6 NA NA NA
1pca 1 P09954 81.55 0.0 X-RAY
 1993-10-31 ASN A:241 A:146 0.0 0.0 -102.1 2.0 0.0 0.0 0.0 VAL
HOH
 8.504
4.405
 N
CB
 OXT
O
2v77 1 P15085 100.0 0.0 X-RAY
 2008-07-01 ASN A:146 A:146 0.0 0.0 -97.7 -0.3 0.0 0.0 0.0 PAY
HOH
 8.684
4.835
 N
O
 O32
O
ASN B:146 B:146 0.0 0.0 -97.1 -0.2 NA NA NA
4uee 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ASN A:146 A:146 0.0 0.0 -109.6 0.6 0.0 0.0 0.0 LA9
HOH
 8.876
4.623
 N
O
 O01
O
ASN B:146 B:146 0.0 0.0 -97.7 3.2 0.0 0.0 0.0 LA9
HOH
 8.885
7.078
 N
OD1
 O01
O
4uef 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ASN A:146 A:256 0.0 0.0 -102.9 4.3 0.0 0.0 0.0 TJE
HOH
 8.654
4.721
 N
O
 O6
O
ASN B:146 B:256 0.0 0.0 -101.5 6.7 NA NA NA
4uez 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ASN A:146 A:256 0.0 0.0 -93.7 1.6 0.0 0.0 0.0 LFF
HOH
 8.839
4.907
 N
N
 O34
O
ASN B:146 B:256 0.0 0.0 -99.9 2.4 NA NA NA
6i6z 1 P15085 100.0 0.0 X-RAY
 2018-12-12 ASN A:146 A:256 0.0 0.0 -104.7 3.9 0.0 0.0 0.0 TJE
HOH
 8.699
4.740
 N
O
 O6
O
ASN B:146 B:256 0.0 0.0 -101.5 3.2 0.0 0.0 0.0 TJE
HOH
 8.783
7.380
 N
OD1
 O6
O
3fju 1 P15085 100.0 0.0 X-RAY
 2008-12-30 ASN A:145 A:146 0.0 0.0 -103.0 -1.7 0.0 0.0 0.0 NA
ACT
HOH
 7.398
8.626
4.778
 OD1
N
O
 NA
OXT
O
1pyt 2 P00730 81.23 0.0 X-RAY
 1997-01-27 ASN B:146 B:146 0.0 0.0 -88.5 -0.4 0.0 0.0 0.0 HOH
 5.259
 O
 O
3kgq 1 P00730 81.23 0.0 X-RAY
 2010-10-27 ASN A:146 A:146 0.0 0.0 -101.8 -3.2 0.0 0.0 0.0 CIT
HOH
 8.505
4.987
 N
O
 O6
O
1arm 1 P00730 80.91 0.0 X-RAY
 1996-08-17 ASN A:146 A:146 0.0 0.0 -94.7 1.4 0.0 0.0 0.0 HOH
 4.981
 O
 O
1ee3 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ASN A:146 P:146 0.0 0.0 -101.2 -0.3 0.0 0.0 0.0 HOH
 4.697
 O
 O
1ell 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ASN A:146 P:146 0.0 0.0 -99.4 -0.2 0.0 0.0 0.0 HOH
 4.749
 O
 O
1elm 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ASN A:146 P:146 0.0 0.0 -96.6 -0.3 0.0 0.0 0.0 HOH
 4.738
 O
 O
1yme 1 P00730 80.91 0.0 X-RAY
 1997-02-12 ASN A:146 A:146 0.0 0.0 -100.7 3.4 0.0 0.0 0.0 HOH
 4.905
 O
 O
1zlh 1 P00730 80.91 0.0 X-RAY
 2005-07-05 ASN A:146 A:146 0.0 0.0 -97.8 -4.9 0.0 0.0 0.0 HOH
 4.812
 O
 O
2abz 1 P00730 80.91 0.0 X-RAY
 2006-01-31 ASN A:146 A:146 0.0 0.0 -101.3 4.2 0.0 0.0 0.0
ASN B:146 B:146 0.0 0.0 -95.3 -6.1 0.0 0.0 0.0
3hlp 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 ASN A:146 A:146 0.0 0.0 -100.4 -2.6 0.0 0.0 0.0 MRD
HOH
 8.020
4.867
 N
O
 C5
O
ASN B:146 B:146 0.0 0.0 -103.3 -2.8 NA NA NA
3huv 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 ASN A:146 A:146 0.0 0.0 -105.4 -4.6 0.0 0.0 0.0 HOH
 4.747
 O
 O
3i1u 1 A6H6Y4 80.91 0.0 X-RAY
 2009-11-17 ASN A:146 A:146 0.0 0.0 -103.0 0.2 0.0 0.0 0.0 BTW
HOH
 8.645
4.848
 N
O
 O1
O
1hdq 1 P00730 81.43 0.0 X-RAY
 2001-11-15 ASN A:146 A:146 0.0 0.0 -98.1 1.6 0.0 0.0 0.0 HOH
 4.942
 O
 O
2ctb 1 P00730 81.43 0.0 X-RAY
 1994-01-31 ASN A:146 A:146 0.0 0.0 -96.9 -0.7 0.0 0.0 0.0 HOH
 4.942
 O
 O
2ctc 1 P00730 81.43 0.0 X-RAY
 1994-01-31 ASN A:146 A:146 0.0 0.0 -96.6 1.2 0.0 0.0 0.0 HFA
HOH
 8.736
4.919
 N
O
 O
O
1arl 1 P00730 81.11 0.0 X-RAY
 1996-08-01 ASN A:146 A:146 0.0 0.0 -95.2 0.6 0.0 0.0 0.0 HOH
 5.028
 O
 O
1cpx 1 P00730 81.11 0.0 X-RAY
 1998-08-05 ASN A:146 A:146 0.0 0.0 -93.1 -8.2 0.0 0.0 0.0 HOH
 5.066
 O
 O
1f57 1 P00730 81.11 0.0 X-RAY
 2000-09-06 ASN A:146 A:146 0.0 0.0 -99.3 0.2 0.0 0.0 0.0 DCY
HOH
 8.750
4.896
 N
O
 O
O
1m4l 1 P00730 81.11 0.0 X-RAY
 2003-01-10 ASN A:146 A:146 0.0 0.0 -102.8 1.0 0.0 0.0 0.0 HOH
 4.962
 O
 O
2rfh 1 A6H6Y4 81.11 0.0 X-RAY
 2008-04-22 ASN A:146 A:146 0.0 0.0 -99.6 -3.1 0.0 0.0 0.0 23N
HOH
 8.804
4.908
 N
O
 CAG
O
3fvl 1 P00730 81.11 0.0 X-RAY
 2010-01-12 ASN A:146 A:146 0.0 0.0 -100.8 -4.0 0.0 0.0 0.0 BHK
HOH
 6.863
5.015
 N
N
 CAJ
O
ASN B:146 C:146 0.0 0.0 -100.8 -3.4 0.0 0.0 0.0 BHK
HOH
 8.001
5.043
 N
N
 CAI
O
ASN C:146 E:146 0.0 0.0 -104.7 -0.6 0.0 0.0 0.0 BHK
HOH
 6.972
4.950
 N
O
 CAI
O
3fx6 1 P00730 81.11 0.0 X-RAY
 2009-08-25 ASN A:146 A:146 0.0 0.0 -101.5 -5.1 0.0 0.0 0.0 BPX
HOH
 9.275
5.014
 N
N
 OAO
O
ASN B:146 C:146 0.0 0.0 -101.9 -2.2 0.0 0.0 0.0 BPX
HOH
 9.399
5.056
 N
N
 OAO
O
ASN C:146 E:146 0.0 0.0 -103.8 -3.7 0.0 0.0 0.0 BPX
HOH
 9.549
4.968
 N
O
 OAO
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15085-f1 1 P15085 100.0 0.0 ASN A:256 A:256 0.0 0.0 -94.9 -3.4