Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 130025006 . C A CCDS5820.1:NM_001868.2:c.807aaC>aaA_NP_001859.1:p.269N>K Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5om9 1 P15085 100.0 0.0 X-RAY
 2017-08-09 ASN A:269 A:159 54.0 0.338 -84.9 114.0 54.0 0.338 0.0 HOH
 4.659
 OD1
 O
ASN B:269 B:159 61.0 0.381 -91.0 116.8 61.0 0.381 0.0 HOH
 6.766
 O
 O
4uf4 1 P15085 99.76 0.0 X-RAY
 2016-01-20 ASN A:269 A:269 57.0 0.356 -85.9 115.0 57.0 0.356 0.0 HOH
 4.229
 OD1
 O
ASN B:269 B:269 61.0 0.381 -90.6 117.1 NA NA NA
1pca 1 P09954 81.55 0.0 X-RAY
 1993-10-31 SER A:254 A:159 38.0 0.33 -96.8 122.3 38.0 0.33 0.0 HOH
 3.341
 OG
 O
2v77 1 P15085 100.0 0.0 X-RAY
 2008-07-01 ASN A:159 A:159 83.0 0.519 -87.0 114.4 83.0 0.519 0.0 EPE
HOH
 8.314
2.675
 ND2
ND2
 C7
O
ASN B:159 B:159 84.0 0.525 -84.0 115.0 NA NA NA
4uee 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ASN A:159 A:159 85.0 0.531 -92.2 114.0 57.0 0.356 0.175 B:P15085:0.175
 LA9
HOH
 9.651
2.918
 ND2
ND2
 C29
O
ASN B:159 B:159 81.0 0.506 -86.7 113.1 52.0 0.325 0.181 A:P15085:0.181
 LA9
HOH
 9.713
4.409
 ND2
N
 C25
O
4uef 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ASN A:159 A:269 88.0 0.55 -89.7 118.0 88.0 0.55 0.0 HOH
 4.416
 N
 O
ASN B:159 B:269 87.0 0.544 -85.8 119.5 NA NA NA
4uez 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ASN A:159 A:269 87.0 0.544 -90.0 118.7 87.0 0.544 0.0 HOH
 2.681
 ND2
 O
ASN B:159 B:269 87.0 0.544 -90.6 119.9 NA NA NA
6i6z 1 P15085 100.0 0.0 X-RAY
 2018-12-12 ASN A:159 A:269 89.0 0.556 -86.7 116.4 71.0 0.444 0.112 B:P15085:0.113
 HOH
 4.350
 N
 O
ASN B:159 B:269 88.0 0.55 -84.4 115.7 69.0 0.431 0.119 A:P15085:0.119
 TJE
HOH
 9.853
2.658
 ND2
OD1
 O2
O
3fju 1 P15085 100.0 0.0 X-RAY
 2008-12-30 ASN A:158 A:159 83.0 0.519 -87.8 114.9 83.0 0.519 0.0 ACT
HOH
 7.814
2.651
 O
OD1
 CH3
O
1pyt 2 P00730 81.23 0.0 X-RAY
 1997-01-27 SER B:159 B:159 58.0 0.504 S -97.2 118.6 55.0 0.478 0.026 A:P00730:0.026
 HOH
 2.616
 OG
 O
3kgq 1 P00730 81.23 0.0 X-RAY
 2010-10-27 SER A:159 A:159 54.0 0.47 -90.7 120.6 54.0 0.47 0.0 HOH
 3.161
 OG
 O
1arm 1 P00730 80.91 0.0 X-RAY
 1996-08-17 SER A:159 A:159 53.0 0.461 -89.4 125.2 53.0 0.461 0.0 HOH
 3.050
 OG
 O
1ee3 1 P00730 80.91 0.0 X-RAY
 2002-06-26 SER A:159 P:159 55.0 0.478 -93.1 117.7 55.0 0.478 0.0 HOH
 2.706
 OG
 O
1ell 1 P00730 80.91 0.0 X-RAY
 2002-06-26 SER A:159 P:159 54.0 0.47 -96.1 119.2 54.0 0.47 0.0 HOH
 2.762
 OG
 O
1elm 1 P00730 80.91 0.0 X-RAY
 2002-06-26 SER A:159 P:159 55.0 0.478 -95.1 120.3 55.0 0.478 0.0 HOH
 2.589
 OG
 O
1yme 1 P00730 80.91 0.0 X-RAY
 1997-02-12 SER A:159 A:159 52.0 0.452 -89.5 123.6 52.0 0.452 0.0 HOH
 2.583
 OG
 O
1zlh 1 P00730 80.91 0.0 X-RAY
 2005-07-05 SER A:159 A:159 53.0 0.461 -83.3 124.1 53.0 0.461 0.0 HOH
 2.622
 OG
 O
2abz 1 P00730 80.91 0.0 X-RAY
 2006-01-31 SER A:159 A:159 47.0 0.409 -95.1 121.3 47.0 0.409 0.0
SER B:159 B:159 48.0 0.417 -103.1 122.2 48.0 0.417 0.0
3hlp 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 SER A:159 A:159 69.0 0.6 -80.8 115.2 69.0 0.6 0.0 HOH
 2.755
 OG
 O
SER B:159 B:159 56.0 0.487 S -90.7 121.9 NA NA NA
3huv 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 SER A:159 A:159 72.0 0.626 -80.8 118.1 72.0 0.626 0.0 HOH
 4.117
 N
 O
3i1u 1 A6H6Y4 80.91 0.0 X-RAY
 2009-11-17 SER A:159 A:159 57.0 0.496 -85.0 118.9 57.0 0.496 0.0 GOL
HOH
 6.801
4.388
 O
N
 O2
O
1hdq 1 P00730 81.43 0.0 X-RAY
 2001-11-15 SER A:159 A:159 53.0 0.461 -92.9 121.3 53.0 0.461 0.0 HOH
 2.735
 OG
 O
2ctb 1 P00730 81.43 0.0 X-RAY
 1994-01-31 SER A:159 A:159 53.0 0.461 -93.7 122.3 53.0 0.461 0.0 HOH
 2.643
 OG
 O
2ctc 1 P00730 81.43 0.0 X-RAY
 1994-01-31 SER A:159 A:159 56.0 0.487 -89.6 123.4 56.0 0.487 0.0 HOH
 2.621
 OG
 O
1arl 1 P00730 81.11 0.0 X-RAY
 1996-08-01 SER A:159 A:159 53.0 0.461 -92.0 123.3 53.0 0.461 0.0 HOH
 2.555
 OG
 O
1cpx 1 P00730 81.11 0.0 X-RAY
 1998-08-05 SER A:159 A:159 55.0 0.478 -86.5 121.9 55.0 0.478 0.0 HOH
 2.754
 OG
 O
1f57 1 P00730 81.11 0.0 X-RAY
 2000-09-06 SER A:159 A:159 55.0 0.478 -86.5 118.2 55.0 0.478 0.0 HOH
 3.219
 OG
 O
1m4l 1 P00730 81.11 0.0 X-RAY
 2003-01-10 SER A:159 A:159 53.0 0.461 -88.7 120.9 53.0 0.461 0.0 HOH
 2.298
 OG
 O
2rfh 1 A6H6Y4 81.11 0.0 X-RAY
 2008-04-22 SER A:159 A:159 51.0 0.443 -88.4 121.9 51.0 0.443 0.0 HOH
 3.582
 CB
 O
3fvl 1 P00730 81.11 0.0 X-RAY
 2010-01-12 SER A:159 A:159 54.0 0.47 -90.2 120.4 54.0 0.47 0.0 HOH
 2.693
 OG
 O
SER B:159 C:159 55.0 0.478 -86.4 120.0 5.0 0.043 0.435 A:P00730:0.435
 HOH
 4.327
 OG
 O
SER C:159 E:159 57.0 0.496 -94.5 116.0 57.0 0.496 0.0 HOH
 2.678
 OG
 O
3fx6 1 P00730 81.11 0.0 X-RAY
 2009-08-25 SER A:159 A:159 54.0 0.47 -91.3 120.3 54.0 0.47 0.0 HOH
 2.710
 OG
 O
SER B:159 C:159 54.0 0.47 -86.6 121.3 4.0 0.035 0.435 A:P00730:0.435
 HOH
 4.354
 OG
 O
SER C:159 E:159 57.0 0.496 -93.9 116.4 57.0 0.496 0.0 HOH
 4.466
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15085-f1 1 P15085 100.0 0.0 ASN A:269 A:269 56.0 0.35 -81.8 119.6