Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 130025008 . C A CCDS5820.1:NM_001868.2:c.809cCc>cAc_NP_001859.1:p.270P>H Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5om9 1 P15085 100.0 0.0 X-RAY
 2017-08-09 PRO A:270 A:160 22.0 0.152 T -53.1 -25.2 22.0 0.152 0.0 HOH
 3.398
 O
 O
PRO B:270 B:160 22.0 0.152 T -55.9 -19.2 22.0 0.152 0.0 HOH
 3.580
 O
 O
4uf4 1 P15085 99.76 0.0 X-RAY
 2016-01-20 PRO A:270 A:270 21.0 0.145 T -53.2 -24.3 21.0 0.145 0.0 HOH
 3.428
 O
 O
PRO B:270 B:270 23.0 0.159 T -58.6 -17.1 NA NA NA
1pca 1 P09954 81.55 0.0 X-RAY
 1993-10-31 PRO A:255 A:160 29.0 0.2 T -65.9 -18.1 29.0 0.2 0.0 HOH
 2.831
 O
 O
2v77 1 P15085 100.0 0.0 X-RAY
 2008-07-01 PRO A:160 A:160 27.0 0.186 T -51.1 -30.3 27.0 0.186 0.0 EPE
HOH
 5.670
3.310
 O
O
 C7
O
PRO B:160 B:160 25.0 0.172 T -52.3 -28.9 NA NA NA
4uee 1 P15085 100.0 0.0 X-RAY
 2016-01-20 PRO A:160 A:160 29.0 0.2 T -52.9 -29.0 29.0 0.2 0.0 LA9
HOH
 9.893
3.971
 O
O
 C29
O
PRO B:160 B:160 29.0 0.2 T -53.1 -26.7 29.0 0.2 0.0 HOH
 5.918
 O
 O
4uef 1 P15085 100.0 0.0 X-RAY
 2016-01-20 PRO A:160 A:270 29.0 0.2 T -59.0 -24.5 29.0 0.2 0.0 HOH
 2.993
 O
 O
PRO B:160 B:270 26.0 0.179 T -62.2 -23.7 NA NA NA
4uez 1 P15085 100.0 0.0 X-RAY
 2016-01-20 PRO A:160 A:270 30.0 0.207 T -58.0 -21.3 30.0 0.207 0.0 HOH
 2.745
 O
 O
PRO B:160 B:270 23.0 0.159 T -61.7 -25.7 NA NA NA
6i6z 1 P15085 100.0 0.0 X-RAY
 2018-12-12 PRO A:160 A:270 30.0 0.207 T -57.6 -24.7 30.0 0.207 0.0 HOH
 3.012
 O
 O
PRO B:160 B:270 26.0 0.179 T -58.3 -24.6 26.0 0.179 0.0 HOH
 3.329
 O
 O
3fju 1 P15085 100.0 0.0 X-RAY
 2008-12-30 PRO A:159 A:160 26.0 0.179 T -57.6 -23.0 26.0 0.179 0.0 ACT
HOH
 5.708
3.362
 O
O
 CH3
O
1pyt 2 P00730 81.23 0.0 X-RAY
 1997-01-27 PRO B:160 B:160 22.0 0.152 T -51.5 -17.1 22.0 0.152 0.0 HOH
 4.019
 CD
 O
3kgq 1 P00730 81.23 0.0 X-RAY
 2010-10-27 PRO A:160 A:160 34.0 0.234 T -55.5 -26.3 34.0 0.234 0.0 HOH
 2.841
 O
 O
1arm 1 P00730 80.91 0.0 X-RAY
 1996-08-17 PRO A:160 A:160 37.0 0.255 T -57.8 -29.2 37.0 0.255 0.0 HOH
 3.235
 O
 O
1ee3 1 P00730 80.91 0.0 X-RAY
 2002-06-26 PRO A:160 P:160 27.0 0.186 T -52.2 -24.2 27.0 0.186 0.0 HOH
 3.157
 O
 O
1ell 1 P00730 80.91 0.0 X-RAY
 2002-06-26 PRO A:160 P:160 26.0 0.179 T -53.1 -26.6 26.0 0.179 0.0 HOH
 3.185
 O
 O
1elm 1 P00730 80.91 0.0 X-RAY
 2002-06-26 PRO A:160 P:160 27.0 0.186 T -53.3 -30.2 27.0 0.186 0.0 HOH
 3.225
 O
 O
1yme 1 P00730 80.91 0.0 X-RAY
 1997-02-12 PRO A:160 A:160 36.0 0.248 T -58.6 -28.8 36.0 0.248 0.0 HOH
 3.091
 O
 O
1zlh 1 P00730 80.91 0.0 X-RAY
 2005-07-05 PRO A:160 A:160 44.0 0.303 T -58.9 -24.7 44.0 0.303 0.0 HOH
 2.919
 O
 O
2abz 1 P00730 80.91 0.0 X-RAY
 2006-01-31 PRO A:160 A:160 44.0 0.303 T -57.6 -25.7 44.0 0.303 0.0
PRO B:160 B:160 55.0 0.379 T -55.5 -28.3 55.0 0.379 0.0
3hlp 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 PRO A:160 A:160 41.0 0.283 T -55.8 -29.9 41.0 0.283 0.0 HOH
 2.760
 O
 O
PRO B:160 B:160 42.0 0.29 T -49.1 -29.2 NA NA NA
3huv 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 PRO A:160 A:160 38.0 0.262 T -58.1 -31.8 38.0 0.262 0.0 HOH
 2.688
 O
 O
3i1u 1 A6H6Y4 80.91 0.0 X-RAY
 2009-11-17 PRO A:160 A:160 37.0 0.255 T -55.8 -30.0 37.0 0.255 0.0 GOL
HOH
 3.615
2.802
 O
O
 O2
O
1hdq 1 P00730 81.43 0.0 X-RAY
 2001-11-15 PRO A:160 A:160 31.0 0.214 T -51.8 -34.3 31.0 0.214 0.0 HOH
 3.084
 O
 O
2ctb 1 P00730 81.43 0.0 X-RAY
 1994-01-31 PRO A:160 A:160 30.0 0.207 T -53.5 -32.5 30.0 0.207 0.0 HOH
 3.203
 O
 O
2ctc 1 P00730 81.43 0.0 X-RAY
 1994-01-31 PRO A:160 A:160 29.0 0.2 T -54.4 -31.4 29.0 0.2 0.0 HOH
 3.586
 O
 O
1arl 1 P00730 81.11 0.0 X-RAY
 1996-08-01 PRO A:160 A:160 38.0 0.262 T -57.1 -29.5 38.0 0.262 0.0 HOH
 3.203
 O
 O
1cpx 1 P00730 81.11 0.0 X-RAY
 1998-08-05 PRO A:160 A:160 30.0 0.207 T -57.6 -24.6 30.0 0.207 0.0 HOH
 3.392
 CD
 O
1f57 1 P00730 81.11 0.0 X-RAY
 2000-09-06 PRO A:160 A:160 35.0 0.241 T -55.7 -27.8 35.0 0.241 0.0 HOH
 2.986
 O
 O
1m4l 1 P00730 81.11 0.0 X-RAY
 2003-01-10 PRO A:160 A:160 32.0 0.221 T -58.8 -27.5 32.0 0.221 0.0 HOH
 3.129
 O
 O
2rfh 1 A6H6Y4 81.11 0.0 X-RAY
 2008-04-22 PRO A:160 A:160 46.0 0.317 T -52.4 -29.3 46.0 0.317 0.0 HOH
 2.910
 O
 O
3fvl 1 P00730 81.11 0.0 X-RAY
 2010-01-12 PRO A:160 A:160 40.0 0.276 T -54.4 -26.5 40.0 0.276 0.0 HOH
 2.938
 O
 O
PRO B:160 C:160 37.0 0.255 T -54.5 -23.7 14.0 0.097 0.158 A:P00730:0.159
 HOH
 2.666
 O
 O
PRO C:160 E:160 30.0 0.207 T -48.2 -32.7 30.0 0.207 0.0 HOH
 2.748
 O
 O
3fx6 1 P00730 81.11 0.0 X-RAY
 2009-08-25 PRO A:160 A:160 43.0 0.297 T -54.7 -26.3 43.0 0.297 0.0 HOH
 3.003
 O
 O
PRO B:160 C:160 37.0 0.255 T -54.6 -26.7 15.0 0.103 0.152 A:P00730:0.152
 HOH
 2.736
 O
 O
PRO C:160 E:160 30.0 0.207 T -48.8 -32.9 30.0 0.207 0.0 HOH
 2.789
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15085-f1 1 P15085 100.0 0.0 PRO A:270 A:270 21.0 0.145 T -57.3 -23.6