Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 130025043 . T A CCDS5820.1:NM_001868.2:c.844Tcc>Acc_NP_001859.1:p.282S>T Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5om9 1 P15085 100.0 0.0 X-RAY
 2017-08-09 SER A:282 A:172 35.0 0.304 -66.5 -28.9 35.0 0.304 0.0 HOH
 3.220
 OG
 O
SER B:282 B:172 32.0 0.278 -63.3 -29.5 32.0 0.278 0.0 HOH
 2.586
 O
 O
4uf4 1 P15085 99.76 0.0 X-RAY
 2016-01-20 SER A:282 A:282 36.0 0.313 -63.4 -31.2 36.0 0.313 0.0 HOH
 3.190
 OG
 O
SER B:282 B:282 32.0 0.278 -62.3 -30.1 NA NA NA
1pca 1 P09954 81.55 0.0 X-RAY
 1993-10-31 SER A:267 A:172 23.0 0.2 -68.0 -24.5 23.0 0.2 0.0 HOH
 4.165
 O
 O
2v77 1 P15085 100.0 0.0 X-RAY
 2008-07-01 SER A:172 A:172 33.0 0.287 -61.5 -32.4 33.0 0.287 0.0 HOH
 2.663
 O
 O
SER B:172 B:172 32.0 0.278 -61.2 -31.2 NA NA NA
4uee 1 P15085 100.0 0.0 X-RAY
 2016-01-20 SER A:172 A:172 33.0 0.287 -56.2 -30.5 33.0 0.287 0.0 HOH
 2.449
 O
 O
SER B:172 B:172 32.0 0.278 -53.9 -35.7 32.0 0.278 0.0 HOH
 4.866
 O
 O
4uef 1 P15085 100.0 0.0 X-RAY
 2016-01-20 SER A:172 A:282 32.0 0.278 -64.9 -30.5 32.0 0.278 0.0 HOH
 3.152
 OG
 O
SER B:172 B:282 31.0 0.27 -62.2 -25.2 NA NA NA
4uez 1 P15085 100.0 0.0 X-RAY
 2016-01-20 SER A:172 A:282 31.0 0.27 -65.4 -24.5 31.0 0.27 0.0 HOH
 3.405
 O
 O
SER B:172 B:282 32.0 0.278 -62.7 -21.6 NA NA NA
6i6z 1 P15085 100.0 0.0 X-RAY
 2018-12-12 SER A:172 A:282 25.0 0.217 -62.9 -31.2 25.0 0.217 0.0 HOH
 3.116
 OG
 O
SER B:172 B:282 32.0 0.278 -62.3 -27.4 32.0 0.278 0.0 HOH
 5.225
 O
 O
3fju 1 P15085 100.0 0.0 X-RAY
 2008-12-30 SER A:171 A:172 32.0 0.278 -57.8 -31.8 32.0 0.278 0.0 NA
HOH
 2.486
2.879
 O
O
 NA
O
1pyt 2 P00730 81.23 0.0 X-RAY
 1997-01-27 SER B:172 B:172 18.0 0.157 -65.8 -23.6 18.0 0.157 0.0 HOH
 3.075
 O
 O
3kgq 1 P00730 81.23 0.0 X-RAY
 2010-10-27 SER A:172 A:172 27.0 0.235 -62.7 -34.0 27.0 0.235 0.0 HOH
 3.162
 OG
 O
1arm 1 P00730 80.91 0.0 X-RAY
 1996-08-17 SER A:172 A:172 17.0 0.148 -70.6 -25.1 17.0 0.148 0.0 HOH
 3.242
 OG
 O
1ee3 1 P00730 80.91 0.0 X-RAY
 2002-06-26 SER A:172 P:172 20.0 0.174 -68.1 -29.4 20.0 0.174 0.0 HOH
 3.119
 OG
 O
1ell 1 P00730 80.91 0.0 X-RAY
 2002-06-26 SER A:172 P:172 22.0 0.191 -67.7 -29.9 22.0 0.191 0.0 HOH
 3.082
 OG
 O
1elm 1 P00730 80.91 0.0 X-RAY
 2002-06-26 SER A:172 P:172 19.0 0.165 -67.7 -30.2 19.0 0.165 0.0 HOH
 3.003
 OG
 O
1yme 1 P00730 80.91 0.0 X-RAY
 1997-02-12 SER A:172 A:172 19.0 0.165 -63.3 -29.3 19.0 0.165 0.0 HOH
 3.188
 O
 O
1zlh 1 P00730 80.91 0.0 X-RAY
 2005-07-05 SER A:172 A:172 18.0 0.157 -61.5 -32.6 18.0 0.157 0.0 HOH
 2.242
 O
 O
2abz 1 P00730 80.91 0.0 X-RAY
 2006-01-31 SER A:172 A:172 30.0 0.261 -60.1 -30.3 30.0 0.261 0.0
SER B:172 B:172 25.0 0.217 -61.1 -29.1 25.0 0.217 0.0
3hlp 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 SER A:172 A:172 26.0 0.226 -62.6 -31.4 26.0 0.226 0.0 HOH
 2.688
 O
 O
SER B:172 B:172 26.0 0.226 -61.1 -33.1 NA NA NA
3huv 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 SER A:172 A:172 25.0 0.217 -59.8 -31.8 25.0 0.217 0.0 HOH
 3.076
 OG
 O
3i1u 1 A6H6Y4 80.91 0.0 X-RAY
 2009-11-17 SER A:172 A:172 27.0 0.235 -61.6 -31.4 27.0 0.235 0.0 GOL
HOH
 7.887
2.698
 O
O
 O3
O
1hdq 1 P00730 81.43 0.0 X-RAY
 2001-11-15 SER A:172 A:172 29.0 0.252 -66.8 -32.8 29.0 0.252 0.0 HOH
 3.216
 O
 O
2ctb 1 P00730 81.43 0.0 X-RAY
 1994-01-31 SER A:172 A:172 29.0 0.252 -64.7 -31.4 29.0 0.252 0.0 HOH
 3.203
 OG
 O
2ctc 1 P00730 81.43 0.0 X-RAY
 1994-01-31 SER A:172 A:172 30.0 0.261 -65.0 -30.6 30.0 0.261 0.0 HOH
 3.392
 OG
 O
1arl 1 P00730 81.11 0.0 X-RAY
 1996-08-01 SER A:172 A:172 20.0 0.174 -66.7 -27.9 20.0 0.174 0.0 HOH
 3.258
 O
 O
1cpx 1 P00730 81.11 0.0 X-RAY
 1998-08-05 SER A:172 A:172 27.0 0.235 -65.4 -29.8 27.0 0.235 0.0 HOH
 2.807
 O
 O
1f57 1 P00730 81.11 0.0 X-RAY
 2000-09-06 SER A:172 A:172 19.0 0.165 -65.6 -31.0 19.0 0.165 0.0 HOH
 3.020
 O
 O
1m4l 1 P00730 81.11 0.0 X-RAY
 2003-01-10 SER A:172 A:172 20.0 0.174 -65.0 -30.9 20.0 0.174 0.0 HOH
 3.188
 OG
 O
2rfh 1 A6H6Y4 81.11 0.0 X-RAY
 2008-04-22 SER A:172 A:172 20.0 0.174 -59.7 -31.9 20.0 0.174 0.0 HOH
 2.442
 O
 O
3fvl 1 P00730 81.11 0.0 X-RAY
 2010-01-12 SER A:172 A:172 23.0 0.2 -67.4 -29.1 23.0 0.2 0.0 HOH
 3.623
 O
 O
SER B:172 C:172 26.0 0.226 -65.6 -33.9 26.0 0.226 0.0 HOH
 3.545
 O
 O
SER C:172 E:172 27.0 0.235 -61.7 -34.2 27.0 0.235 0.0 HOH
 3.551
 O
 O
3fx6 1 P00730 81.11 0.0 X-RAY
 2009-08-25 SER A:172 A:172 27.0 0.235 -67.6 -29.7 27.0 0.235 0.0 HOH
 3.638
 O
 O
SER B:172 C:172 19.0 0.165 -66.8 -34.8 19.0 0.165 0.0 HOH
 3.587
 O
 O
SER C:172 E:172 26.0 0.226 -61.3 -33.9 26.0 0.226 0.0 HOH
 3.539
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15085-f1 1 P15085 100.0 0.0 SER A:282 A:282 31.0 0.27 -67.3 -29.1