Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 130027686 . T A CCDS5820.1:NM_001868.2:c.1094aTt>aAt_NP_001859.1:p.365I>N Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5om9 1 P15085 100.0 0.0 X-RAY
 2017-08-09 ILE A:365 A:255 2.0 0.011 H -77.7 -16.0 2.0 0.011 0.0 O2S
HOH
 6.328
2.941
 CG1
N
 C07
O
ILE B:365 B:255 1.0 0.006 H -80.0 -18.2 1.0 0.006 0.0 O2S
HOH
 6.166
2.832
 CG1
N
 C07
O
4uf4 1 P15085 99.76 0.0 X-RAY
 2016-01-20 ILE A:365 A:365 2.0 0.011 H -77.8 -18.8 2.0 0.011 0.0 O2V
HOH
 6.335
2.915
 CD1
N
 C07
O
ILE B:365 B:365 1.0 0.006 H -81.0 -18.2 NA NA NA
1pca 1 P09954 81.55 0.0 X-RAY
 1993-10-31 ILE A:350 A:255 4.0 0.023 H -67.2 -22.7 4.0 0.023 0.0 VAL
HOH
 6.423
3.296
 CG1
N
 CG2
O
2v77 1 P15085 100.0 0.0 X-RAY
 2008-07-01 ILE A:255 A:255 3.0 0.017 H -69.2 -17.4 3.0 0.017 0.0 PAY
HOH
 5.965
3.344
 CG1
N
 O42
O
ILE B:255 B:255 3.0 0.017 H -69.5 -20.5 NA NA NA
4uee 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ILE A:255 A:255 3.0 0.017 H -79.9 -15.9 3.0 0.017 0.0 LA9
HOH
 4.952
3.097
 CG1
N
 C11
O
ILE B:255 B:255 3.0 0.017 H -74.2 -21.3 3.0 0.017 0.0 LA9
HOH
 4.563
3.161
 CG1
N
 C11
O
4uef 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ILE A:255 A:365 4.0 0.023 H -78.7 -18.6 4.0 0.023 0.0 TJE
HOH
 4.456
3.186
 CG1
N
 C22
O
ILE B:255 B:365 4.0 0.023 H -80.6 -20.1 NA NA NA
4uez 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ILE A:255 A:365 1.0 0.006 H -78.0 -23.6 1.0 0.006 0.0 LFF
HOH
 4.877
3.262
 CG1
N
 C30
O
ILE B:255 B:365 1.0 0.006 H -82.3 -23.5 NA NA NA
6i6z 1 P15085 100.0 0.0 X-RAY
 2018-12-12 ILE A:255 A:365 3.0 0.017 H -81.9 -14.7 3.0 0.017 0.0 TJE
HOH
 4.501
3.229
 CG1
N
 C22
O
ILE B:255 B:365 4.0 0.023 H -81.0 -16.2 4.0 0.023 0.0 TJE
HOH
 4.447
3.145
 CG1
N
 C22
O
3fju 1 P15085 100.0 0.0 X-RAY
 2008-12-30 ILE A:254 A:255 0.0 0.0 H -71.3 -23.3 0.0 0.0 0.0 ACT
HOH
 9.189
3.143
 CG1
N
 CH3
O
1pyt 2 P00730 81.23 0.0 X-RAY
 1997-01-27 ILE B:255 B:255 2.0 0.011 H -62.3 -21.1 2.0 0.011 0.0 HOH
 3.695
 CG1
 O
3kgq 1 P00730 81.23 0.0 X-RAY
 2010-10-27 ILE A:255 A:255 1.0 0.006 H -77.9 -21.6 1.0 0.006 0.0 CIT
HOH
 5.768
3.508
 CG1
N
 O4
O
1arm 1 P00730 80.91 0.0 X-RAY
 1996-08-17 ILE A:255 A:255 2.0 0.011 H -71.3 -23.9 2.0 0.011 0.0 HOH
 3.415
 N
 O
1ee3 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ILE A:255 P:255 2.0 0.011 H -75.1 -22.1 2.0 0.011 0.0 HOH
 3.388
 CG1
 O
1ell 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ILE A:255 P:255 2.0 0.011 H -73.2 -21.1 2.0 0.011 0.0 HOH
 3.403
 CG1
 O
1elm 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ILE A:255 P:255 1.0 0.006 H -71.1 -24.7 1.0 0.006 0.0 HOH
 3.333
 CG1
 O
1yme 1 P00730 80.91 0.0 X-RAY
 1997-02-12 ILE A:255 A:255 1.0 0.006 H -71.9 -25.5 1.0 0.006 0.0 HOH
 3.435
 CG1
 O
1zlh 1 P00730 80.91 0.0 X-RAY
 2005-07-05 ILE A:255 A:255 1.0 0.006 H -76.4 -22.1 1.0 0.006 0.0 HOH
 3.363
 CG1
 O
2abz 1 P00730 80.91 0.0 X-RAY
 2006-01-31 ILE A:255 A:255 2.0 0.011 H -78.4 -25.8 2.0 0.011 0.0
ILE B:255 B:255 1.0 0.006 H -78.1 -22.9 1.0 0.006 0.0
3hlp 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 ILE A:255 A:255 2.0 0.011 H -77.2 -21.8 2.0 0.011 0.0 MRD
HOH
 6.042
3.338
 CG1
CG1
 CM
O
ILE B:255 B:255 1.0 0.006 H -78.9 -20.4 NA NA NA
3huv 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 ILE A:255 A:255 1.0 0.006 H -72.7 -26.4 1.0 0.006 0.0 HOH
 3.350
 CG1
 O
3i1u 1 A6H6Y4 80.91 0.0 X-RAY
 2009-11-17 ILE A:255 A:255 1.0 0.006 H -72.9 -22.5 1.0 0.006 0.0 BTW
HOH
 4.568
3.201
 CG1
N
 C9
O
1hdq 1 P00730 81.43 0.0 X-RAY
 2001-11-15 ILE A:255 A:255 2.0 0.011 H -74.4 -20.7 2.0 0.011 0.0 INF
HOH
 6.495
3.423
 CD1
CG1
 CZ
O
2ctb 1 P00730 81.43 0.0 X-RAY
 1994-01-31 ILE A:255 A:255 5.0 0.029 H -74.5 -21.5 5.0 0.029 0.0 HOH
 3.505
 CG1
 O
2ctc 1 P00730 81.43 0.0 X-RAY
 1994-01-31 ILE A:255 A:255 3.0 0.017 H -72.0 -23.0 3.0 0.017 0.0 HFA
HOH
 4.173
3.343
 CG1
N
 CE2
O
1arl 1 P00730 81.11 0.0 X-RAY
 1996-08-01 ILE A:255 A:255 1.0 0.006 H -70.5 -22.5 1.0 0.006 0.0 HOH
 3.104
 CG1
 O
1cpx 1 P00730 81.11 0.0 X-RAY
 1998-08-05 ILE A:255 A:255 2.0 0.011 H -67.5 -23.8 2.0 0.011 0.0 HOH
 3.394
 CG1
 O
1f57 1 P00730 81.11 0.0 X-RAY
 2000-09-06 ILE A:255 A:255 2.0 0.011 H -74.7 -18.9 2.0 0.011 0.0 DCY
HOH
 9.179
3.411
 N
CG1
 O
O
1m4l 1 P00730 81.11 0.0 X-RAY
 2003-01-10 ILE A:255 A:255 2.0 0.011 H -77.4 -20.4 2.0 0.011 0.0 HOH
 3.452
 CG1
 O
2rfh 1 A6H6Y4 81.11 0.0 X-RAY
 2008-04-22 ILE A:255 A:255 1.0 0.006 H -78.5 -23.2 1.0 0.006 0.0 23N
HOH
 4.946
3.328
 CG1
N
 CAE
O
3fvl 1 P00730 81.11 0.0 X-RAY
 2010-01-12 ILE A:255 A:255 1.0 0.006 H -76.0 -18.2 1.0 0.006 0.0 BHK
HOH
 6.212
3.357
 CG1
CG1
 CAK
O
ILE B:255 C:255 2.0 0.011 H -75.4 -17.4 2.0 0.011 0.0 BHK
HOH
 5.439
3.515
 CG1
CG1
 CAK
O
ILE C:255 E:255 1.0 0.006 H -73.5 -18.7 1.0 0.006 0.0 BHK
HOH
 6.131
3.419
 CG1
CG1
 CAK
O
3fx6 1 P00730 81.11 0.0 X-RAY
 2009-08-25 ILE A:255 A:255 1.0 0.006 H -75.9 -17.4 1.0 0.006 0.0 BPX
HOH
 5.596
3.373
 CG1
CG1
 CAE
O
ILE B:255 C:255 1.0 0.006 H -75.9 -16.2 1.0 0.006 0.0 BPX
HOH
 5.536
3.530
 CG1
CG1
 CAE
O
ILE C:255 E:255 1.0 0.006 H -72.7 -18.5 1.0 0.006 0.0 BPX
HOH
 5.552
3.416
 CD1
CG1
 CAE
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15085-f1 1 P15085 100.0 0.0 ILE A:365 A:365 2.0 0.011 H -77.5 -23.3