Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 25163384 . C A CCDS5393.1:NM_018947.5:c.254gGc>gTc_NP_061820.1:p.85G>V Homo sapiens cytochrome c, somatic (CYCS), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n9i 1 P99999 100.0 2e-73 NMR
 2016-02-17 GLY A:84 A:84 14.0 0.187 135.5 177.4 14.0 0.187 0.0 HEC
 5.406
 HA2
 HBB2
2n9j 1 P99999 100.0 2e-73 NMR
 2016-02-17 GLY A:84 A:84 19.0 0.253 118.1 176.9 19.0 0.253 0.0 HEC
 6.522
 HA2
 HBB2
3zcf 1 P99999 100.0 2e-73 X-RAY
 2013-10-23 GLY A:84 A:84 5.0 0.067 114.5 169.6 5.0 0.067 0.0 HEC
HOH
 6.520
2.742
 C
O
 CBB
O
GLY B:84 B:84 20.0 0.267 125.2 172.7 NA NA NA
GLY C:84 C:84 14.0 0.187 118.2 176.8 NA NA NA
GLY D:84 D:84 4.0 0.053 112.3 173.2 NA NA NA
2n3y 1 P99999 99.04 7e-73 NMR
 2016-12-14 GLY A:84 A:84 23.0 0.307 165.7 144.9 23.0 0.307 0.0 MH0
 6.094
 HA2
 H19
3zoo 1 P99999 99.04 7e-73 X-RAY
 2013-10-23 GLY A:84 A:84 6.0 0.08 107.5 170.3 6.0 0.08 0.0 HEC
PO4
HOH
 6.489
6.521
2.730
 C
O
O
 CBB
O3
O
GLY B:84 B:84 20.0 0.267 125.4 169.7 NA NA NA
GLY C:84 C:84 12.0 0.16 117.5 174.7 NA NA NA
GLY D:84 D:84 7.0 0.093 117.2 170.6 NA NA NA
5ty3 1 P99999 99.04 9e-73 X-RAY
 2017-09-06 GLY A:84 A:84 6.0 0.08 112.1 174.8 6.0 0.08 0.0 HEC
HOH
 5.166
2.778
 HA2
O
 HBB2
O
GLY B:84 B:84 8.0 0.107 105.3 169.7 NA NA NA
6xnk 1 P99999 99.04 9e-73 X-RAY
 2021-07-07 GLY A:84 A:84 24.0 0.32 H -60.1 -32.0 24.0 0.32 0.0 HEC
HOH
 5.370
2.788
 N
HA2
 HBC3
O
GLY B:84 C:84 33.0 0.44 H -60.3 -35.2 33.0 0.44 0.0 HEC
HOH
 5.642
2.808
 N
O
 HBC1
O
GLY C:84 E:84 37.0 0.493 H -60.9 -32.8 NA NA NA
GLY D:84 G:84 38.0 0.507 H -59.1 -31.7 NA NA NA
3nwv 1 P99999 99.04 1e-72 X-RAY
 2011-03-09 GLY A:84 A:84 18.0 0.24 118.1 172.2 18.0 0.24 0.0 HEC
HOH
 6.693
2.755
 C
O
 CBB
O
GLY B:84 B:84 15.0 0.2 117.8 168.4 NA NA NA
GLY C:84 C:84 11.0 0.147 123.2 170.3 NA NA NA
GLY D:84 D:84 13.0 0.173 122.7 169.9 NA NA NA
5exq 1 P99999 99.04 1e-72 X-RAY
 2016-11-30 GLY A:84 A:84 12.0 0.16 113.7 169.1 12.0 0.16 0.0 HEC
HOH
 6.454
2.816
 C
O
 CBB
O
GLY B:84 B:84 12.0 0.16 111.9 173.4 NA NA NA
5o10 1 P99999 99.04 1e-72 X-RAY
 2018-03-28 GLY A:84 A:84 6.0 0.08 114.3 169.8 6.0 0.08 0.0 HEC
HOH
 6.240
2.746
 C
O
 CBB
O
GLY B:84 B:84 9.0 0.12 112.6 165.6 9.0 0.12 0.0 HEC
HOH
 6.447
2.698
 C
O
 CBB
O
6duj 1 P99999 99.04 1e-72 X-RAY
 2019-06-26 GLY A:84 A:84 7.0 0.093 120.3 167.4 7.0 0.093 0.0 HEC
HOH
 5.542
2.987
 HA2
O
 HBB1
O
GLY B:84 C:84 7.0 0.093 125.4 171.7 NA NA NA
6ecj 1 P99999 99.04 2e-72 X-RAY
 2019-08-14 GLY A:84 A:84 9.0 0.12 123.0 165.5 9.0 0.12 0.0 HEC
HOH
 7.129
7.552
 C
N
 CBB
O
GLY B:84 B:84 11.0 0.147 121.8 166.0 NA NA NA
GLY C:84 C:84 13.0 0.173 123.4 166.6 NA NA NA
GLY D:84 D:84 6.0 0.08 122.5 165.0 NA NA NA
GLY E:84 E:84 14.0 0.187 123.0 166.1 NA NA NA
GLY F:84 F:84 11.0 0.147 123.0 165.8 NA NA NA
GLY G:84 G:84 17.0 0.227 121.7 165.7 NA NA NA
GLY H:84 H:84 24.0 0.32 123.2 167.3 NA NA NA
5dfs 1 P00003 95.24 3e-71 X-RAY
 2016-03-02 GLY A:85 A:84 10.0 0.133 117.0 166.8 10.0 0.133 0.0 HEC
HOH
 5.386
2.739
 HA2
O
 HBB2
O
GLY B:85 B:84 19.0 0.253 136.1 162.1 NA NA NA
5c0z 1 P62898 91.43 7e-68 X-RAY
 2016-09-21 GLY A:85 A:84 21.0 0.28 124.7 168.1 21.0 0.28 0.0 HEC
FC6
HOH
 6.580
3.640
2.732
 C
O
O
 CBB
N24
O
GLY B:85 B:84 21.0 0.28 127.4 169.0 NA NA NA
GLY C:85 C:84 22.0 0.293 129.0 163.6 NA NA NA
GLY D:85 D:84 22.0 0.293 126.8 162.7 NA NA NA
5c9m 1 P62898 90.48 3e-67 X-RAY
 2016-09-21 GLY A:85 A:84 22.0 0.293 124.7 167.1 22.0 0.293 0.0 HEC
FC6
HOH
 6.668
3.654
2.720
 C
O
O
 CBB
N24
O
GLY B:85 B:84 20.0 0.267 127.2 167.9 NA NA NA
GLY C:85 C:84 21.0 0.28 129.3 165.6 NA NA NA
GLY D:85 D:84 19.0 0.253 129.1 166.6 NA NA NA
7ljx 1 P62898 90.38 1e-66 X-RAY
 2021-05-12 GLY A:84 A:84 14.0 0.187 120.7 167.7 14.0 0.187 0.0 HEC
HOH
 6.557
3.643
 C
O
 CBB
O
GLY B:84 B:84 17.0 0.227 120.5 166.8 NA NA NA
2b4z 1 P62894 90.38 2e-66 X-RAY
 2005-10-11 GLY A:84 A:84 20.0 0.267 121.6 165.7 20.0 0.267 0.0 HEM
HOH
 6.649
2.843
 C
O
 CBB
O
2ybb 33 P62894 90.38 2e-66 EM
 2011-10-19 GLY GA:84 Y:84 20.0 0.267 121.6 165.6 11.0 0.147 0.12 KA:P00125:0.12
 HEM
HOH
 6.648
2.842
 C
O
 CBB
O
3j2t 2 P62894 90.38 2e-66 EM
 2013-04-10 GLY H:84 H:84 21.0 0.28 121.5 165.7 21.0 0.28 0.0 HEM
 6.649
 C
 CBB
GLY I:84 I:84 20.0 0.267 121.5 165.7 20.0 0.267 0.0 HEM
 6.649
 C
 CBB
GLY J:84 J:84 19.0 0.253 121.5 165.7 19.0 0.253 0.0 HEM
 6.648
 C
 CBB
GLY K:84 K:84 19.0 0.253 121.5 165.7 19.0 0.253 0.0 HEM
 6.649
 C
 CBB
GLY L:84 L:84 20.0 0.267 121.5 165.7 20.0 0.267 0.0 HEM
 6.649
 C
 CBB
GLY M:84 M:84 21.0 0.28 121.5 165.8 21.0 0.28 0.0 HEM
 6.649
 C
 CBB
GLY N:84 N:84 21.0 0.28 121.5 165.7 21.0 0.28 0.0 HEM
 6.649
 C
 CBB
5juy 2 P62894 90.38 2e-66 EM
 2016-10-19 GLY H:84 H:84 12.0 0.16 97.2 145.2 11.0 0.147 0.013 A:O14727:0.013
 HEC
 7.477
 C
 CBB
GLY I:84 I:84 12.0 0.16 97.2 145.3 11.0 0.147 0.013 B:O14727:0.013
 HEC
 7.476
 C
 CBB
GLY J:84 J:84 11.0 0.147 97.2 145.3 10.0 0.133 0.014 C:O14727:0.013
 HEC
 7.477
 C
 CBB
GLY K:84 K:84 12.0 0.16 97.2 145.3 11.0 0.147 0.013 D:O14727:0.013
 HEC
 7.477
 C
 CBB
GLY L:84 L:84 11.0 0.147 97.2 145.3 10.0 0.133 0.014 E:O14727:0.013
 HEC
 7.477
 C
 CBB
GLY M:84 M:84 11.0 0.147 97.1 145.3 11.0 0.147 0.0 HEC
 7.477
 C
 CBB
GLY N:84 N:84 12.0 0.16 97.2 145.3 11.0 0.147 0.013 G:O14727:0.013
 HEC
 7.477
 C
 CBB
6ff5 1 P62894 90.38 2e-66 X-RAY
 2018-03-21 GLY A:84 A:84 24.0 0.32 131.9 159.6 24.0 0.32 0.0 HEC
NO3
NO3
NO3
HOH
 7.125
3.039
3.649
3.559
2.972
 CA
N
O
O
O
 CBB
O3
O1
O1
O
6n1o 1 P62898 90.38 4e-66 X-RAY
 2019-10-23 GLY A:84 A:84 21.0 0.28 123.4 167.8 21.0 0.28 0.0 HEC
EDO
HOH
 6.523
5.511
2.903
 C
O
O
 CBB
C2
O
GLY B:84 B:84 22.0 0.293 123.0 166.3 NA NA NA
GLY C:84 C:84 22.0 0.293 124.0 165.7 NA NA NA
GLY D:84 D:84 20.0 0.267 123.0 167.2 NA NA NA
3jbt 2 P00004 88.57 4e-66 EM
 2015-11-18 GLY B:85 B:84 19.0 0.253 133.6 156.2 19.0 0.253 0.0 HEM
 7.285
 C
 CBB
GLY D:85 D:84 19.0 0.253 133.5 156.2 19.0 0.253 0.0 HEM
 7.285
 C
 CBB
GLY F:85 F:84 19.0 0.253 133.5 156.1 19.0 0.253 0.0 HEM
 7.285
 C
 CBB
GLY H:85 H:84 19.0 0.253 133.5 156.2 19.0 0.253 0.0 HEM
 7.284
 C
 CBB
GLY J:85 J:84 19.0 0.253 133.5 156.2 19.0 0.253 0.0 HEM
 7.284
 C
 CBB
GLY L:85 L:84 19.0 0.253 133.5 156.2 19.0 0.253 0.0 HEM
 7.283
 C
 CBB
GLY N:85 N:84 19.0 0.253 133.5 156.2 19.0 0.253 0.0 HEM
 7.283
 C
 CBB
5wve 2 P00004 88.57 4e-66 EM
 2017-02-08 GLY B:85 B:84 20.0 0.267 133.6 156.1 20.0 0.267 0.0 HEM
 7.284
 C
 CBB
GLY D:85 D:84 19.0 0.253 133.6 156.2 19.0 0.253 0.0 HEM
 7.284
 C
 CBB
GLY F:85 F:84 19.0 0.253 133.6 156.2 19.0 0.253 0.0 HEM
 7.284
 C
 CBB
GLY H:85 H:84 18.0 0.24 133.6 156.2 18.0 0.24 0.0 HEM
 7.284
 C
 CBB
GLY J:85 J:84 20.0 0.267 133.5 156.1 20.0 0.267 0.0 HEM
 7.284
 C
 CBB
GLY L:85 L:84 19.0 0.253 133.5 156.1 19.0 0.253 0.0 HEM
 7.285
 C
 CBB
GLY N:85 N:84 20.0 0.267 133.5 156.3 20.0 0.267 0.0 HEM
 7.282
 C
 CBB
5df5 1 P62898 90.38 5e-66 X-RAY
 2016-09-14 GLY A:84 A:84 21.0 0.28 123.0 166.0 21.0 0.28 0.0 HEC
HOH
 6.712
2.697
 C
O
 CBB
O
GLY B:84 B:84 14.0 0.187 120.8 166.4 NA NA NA
GLY C:84 C:84 19.0 0.253 124.7 163.2 NA NA NA
GLY D:84 D:84 20.0 0.267 128.8 166.2 NA NA NA
1ocd 1 P00004 88.46 3e-65 NMR
 1997-06-16 GLY A:84 A:84 36.0 0.48 S -108.2 -71.0 36.0 0.48 0.0 HEC
HOH
 4.316
6.231
 H
H
 HBB2
O
1u75 2 P00004 88.46 3e-65 X-RAY
 2004-09-28 GLY B:84 B:84 16.0 0.213 81.7 154.7 16.0 0.213 0.0 HEC
HOH
 6.857
6.177
 CA
N
 CBB
O
2frc 1 P00004 88.46 3e-65 NMR
 1997-07-29 GLY A:84 A:84 53.0 0.707 171.8 167.4 53.0 0.707 0.0 HEC
HOH
 5.972
3.964
 H
H
 HBB3
O
2n3b 1 P00004 88.46 3e-65 NMR
 2015-10-28 GLY A:84 A:84 26.0 0.347 -75.0 -179.0 26.0 0.347 0.0 HEC
 5.224
 HA2
 HBB1
2pcb 2 P00004 88.46 3e-65 X-RAY
 1993-07-15 GLY B:84 B:84 3.0 0.04 60.5 161.2 3.0 0.04 0.0 HEM
HOH
 6.833
4.089
 CA
N
 CBB
O
3nbs 1 P00004 88.46 3e-65 X-RAY
 2010-07-14 GLY A:84 A:84 64.0 0.853 -75.0 160.6 38.0 0.507 0.346 B:P00004:0.347
 HEC
HOH
 7.276
3.523
 C
CA
 CBB
O
GLY B:84 B:84 47.0 0.627 -85.7 164.2 21.0 0.28 0.347 A:P00004:0.347
 HEC
HOH
 6.825
3.314
 C
N
 CBB
O
GLY C:84 C:84 65.0 0.867 -85.1 165.8 NA NA NA
GLY D:84 D:84 42.0 0.56 -91.3 159.3 NA NA NA
3nbt 1 P00004 88.46 3e-65 X-RAY
 2010-07-14 GLY A:84 A:84 45.0 0.6 124.1 175.0 22.0 0.293 0.307 F:P00004:0.307
 HEC
PEG
HEC
HOH
 9.298
3.480
6.461
2.771
 O
O
C
O
 O1D
O1
CBB
O
GLY B:84 B:84 49.0 0.653 129.5 168.9 NA NA NA
GLY C:84 C:84 48.0 0.64 121.7 166.7 NA NA NA
GLY D:84 D:84 44.0 0.587 117.7 171.7 NA NA NA
GLY E:84 E:84 45.0 0.6 120.3 163.6 24.0 0.32 0.28 A:P00004:0.28
 HEC
HEC
PEG
HOH
 6.610
9.282
3.763
2.936
 C
O
O
O
 CBB
O1D
O4
O
GLY F:84 F:84 48.0 0.64 125.0 168.6 24.0 0.32 0.32 E:P00004:0.32
 HEC
HEC
PGE
HOH
 6.778
9.550
3.370
2.991
 C
O
O
O
 CBB
O1D
C6
O
3wc8 1 P00004 88.46 3e-65 X-RAY
 2013-12-11 GLY A:84 A:84 36.0 0.48 -92.9 -174.6 11.0 0.147 0.333 A:P00004:0.333
 PEG
HEC
HOH
 9.215
5.145
2.846
 N
O
O
 O4
CBB
O
3wui 1 P00004 88.46 3e-65 X-RAY
 2014-07-16 GLY A:84 A:84 35.0 0.467 S -96.8 -172.1 10.0 0.133 0.334 A:P00004:0.333
 PEG
PEG
HEC
HOH
 9.836
9.810
5.018
3.957
 N
N
O
O
 O1
O4
CBB
O
4rsz 1 P00004 88.46 3e-65 X-RAY
 2015-01-14 GLY A:84 A:84 18.0 0.24 133.6 156.2 18.0 0.24 0.0 HEC
NO3
HOH
 7.264
2.797
4.009
 C
N
O
 CBB
O3
O
GLY B:84 B:84 15.0 0.2 139.0 158.5 NA NA NA
GLY C:84 C:84 20.0 0.267 139.3 156.5 NA NA NA
GLY D:84 D:84 19.0 0.253 138.6 158.4 NA NA NA
GLY E:84 E:84 18.0 0.24 138.7 156.1 NA NA NA
GLY F:84 F:84 19.0 0.253 139.7 158.4 NA NA NA
6suv 1 P00004 88.46 3e-65 X-RAY
 2020-07-22 GLY A:84 AaA:84 19.0 0.253 125.9 162.7 19.0 0.253 0.0 HEC
LVQ
HOH
 6.463
7.641
8.328
 C
O
CA
 CBB
O06
O
GLY B:84 BaB:84 19.0 0.253 126.5 162.1 NA NA NA
GLY C:84 CaC:84 20.0 0.267 125.3 162.3 NA NA NA
GLY D:84 DaD:84 14.0 0.187 127.0 163.3 NA NA NA
GLY E:84 EaE:84 18.0 0.24 125.6 162.3 NA NA NA
GLY F:84 FaF:84 18.0 0.24 125.4 162.9 NA NA NA
GLY G:84 GaG:84 17.0 0.227 126.1 162.9 NA NA NA
GLY H:84 HaH:84 17.0 0.227 125.7 163.4 NA NA NA
1crc 1 P00004 88.46 3e-65 X-RAY
 1996-03-08 GLY A:85 A:84 17.0 0.227 127.6 162.3 17.0 0.227 0.0 HEC
HOH
 6.708
3.234
 C
O
 CBB
O
GLY B:85 B:84 17.0 0.227 124.9 179.2 NA NA NA
1hrc 1 P00004 88.46 3e-65 X-RAY
 1994-11-01 GLY A:85 A:84 17.0 0.227 115.2 177.2 17.0 0.227 0.0 HEC
HOH
 6.328
4.479
 C
C
 CBB
O
1wej 3 P00004 88.46 3e-65 X-RAY
 1998-12-09 GLY C:85 F:84 24.0 0.32 119.4 164.6 24.0 0.32 0.0 HEM
HOH
 6.808
2.817
 C
O
 CBB
O
3o1y 1 P00004 88.46 3e-65 X-RAY
 2012-01-25 GLY A:85 A:84 24.0 0.32 137.4 156.1 24.0 0.32 0.0 HEC
NO3
NO3
HOH
 7.063
6.855
2.970
2.936
 C
O
N
O
 CBB
O2
O2
O
GLY B:85 B:84 24.0 0.32 137.1 159.2 NA NA NA
GLY C:85 C:84 20.0 0.267 133.7 163.6 NA NA NA
3o20 1 P00004 88.46 3e-65 X-RAY
 2012-01-25 GLY A:85 A:84 16.0 0.213 119.9 151.5 16.0 0.213 0.0 HEC
NO3
NO3
HOH
 7.039
2.904
3.491
2.552
 CA
N
O
O
 CBB
O2
O1
O
GLY B:85 B:84 18.0 0.24 134.2 161.5 NA NA NA
GLY C:85 C:84 14.0 0.187 120.7 156.3 NA NA NA
5iy5 14 P00004 88.46 3e-65 X-RAY
 2017-01-11 GLY AA:85 1:84 17.0 0.227 125.6 168.2 17.0 0.227 0.0 HEC
HOH
 6.736
3.493
 CA
O
 CBB
O
GLY BA:85 2:84 15.0 0.2 150.1 158.4 NA NA NA
6k9i 1 P00004 88.46 3e-65 X-RAY
 2020-06-17 GLY A:85 A:84 13.0 0.173 110.5 169.7 13.0 0.173 0.0 HEC
HOH
 6.575
4.990
 C
N
 CBB
O
6k9j 1 P00004 88.46 3e-65 X-RAY
 2020-06-17 GLY A:85 A:84 6.0 0.08 114.3 160.7 6.0 0.08 0.0 HEC
HOH
 6.156
2.406
 C
O
 CBB
O
5zkv 1 P00004 87.5 6e-64 NMR
 2019-05-22 GLY A:84 A:84 50.0 0.667 S -80.0 14.7 50.0 0.667 0.0 HEC
 5.712
 H
 HMC2
4nfg 2 P00004 85.58 5e-63 X-RAY
 2014-09-24 GLY B:84 B:84 8.0 0.107 137.2 144.4 8.0 0.107 0.0 HEC
HOH
 7.107
2.740
 C
O
 CBB
O
2aiu 1 P00015 83.65 2e-62 X-RAY
 2006-07-18 GLY A:85 A:85 17.0 0.227 110.3 172.9 17.0 0.227 0.0 HEM
HOH
 6.270
2.876
 C
O
 CBB
O
1cyc 1 P00025 80.58 3e-58 X-RAY
 1976-10-06 GLY A:84 A:84 9.0 0.12 -136.3 -99.4 9.0 0.12 0.0 HEC
 6.549
 O
 CBB
GLY B:84 B:84 9.0 0.12 -136.3 -99.4 NA NA NA
1i54 1 P81459 80.58 3e-58 X-RAY
 2001-05-09 GLY A:84 A:84 12.0 0.16 113.7 163.6 12.0 0.16 0.0 HEC
ZNH
HOH
 6.328
6.332
3.103
 C
C
O
 CBB
CBB
O
GLY B:84 B:84 12.0 0.16 111.1 164.3 NA NA NA
1i55 1 P81459 80.58 3e-58 X-RAY
 2001-05-09 GLY A:84 A:84 12.0 0.16 113.0 162.5 12.0 0.16 0.0 HEC
ZNH
HOH
 6.335
6.338
3.097
 C
C
O
 CBB
CBB
O
GLY B:84 B:84 13.0 0.173 111.5 165.3 NA NA NA
1lfm 1 P81459 80.58 3e-58 X-RAY
 2002-07-19 GLY A:84 A:84 12.0 0.16 118.0 160.8 12.0 0.16 0.0 COH
HOH
 6.214
2.874
 C
O
 CBB
O
GLY B:84 B:84 12.0 0.16 120.4 162.2 NA NA NA
3cyt 1 P81459 80.58 3e-58 X-RAY
 1980-09-16 GLY A:85 O:84 14.0 0.187 128.3 169.7 14.0 0.187 0.0 HEC
HOH
 6.342
4.914
 C
N
 CBB
O
GLY B:85 I:84 11.0 0.147 120.4 153.0 NA NA NA
5cyt 1 P81459 80.58 3e-58 X-RAY
 1989-07-12 GLY A:85 R:84 15.0 0.2 120.5 163.3 15.0 0.2 0.0 HEC
HOH
 6.422
3.017
 C
O
 CBB
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p99999-f1 1 P99999 100.0 1e-74 GLY A:85 A:85 10.0 0.133 93.6 170.0