Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 25163615 . C A CCDS5393.1:NM_018947.5:c.124Ggt>Tgt_NP_061820.1:p.42G>C Homo sapiens cytochrome c, somatic (CYCS), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n9i 1 P99999 100.0 2e-73 NMR
 2016-02-17 GLY A:41 A:41 24.0 0.32 S 45.8 39.5 24.0 0.32 0.0 HEC
 4.305
 H
 HBA2
2n9j 1 P99999 100.0 2e-73 NMR
 2016-02-17 GLY A:41 A:41 17.0 0.227 S 60.7 39.2 17.0 0.227 0.0 HEC
 2.704
 H
 O2A
3zcf 1 P99999 100.0 2e-73 X-RAY
 2013-10-23 GLY A:41 A:41 8.0 0.107 T 74.1 35.0 8.0 0.107 0.0 HEC
HOH
 2.910
3.460
 N
N
 O2A
O
GLY B:41 B:41 2.0 0.027 T 78.6 35.5 NA NA NA
GLY C:41 C:41 8.0 0.107 T 77.8 33.8 NA NA NA
GLY D:41 D:41 1.0 0.013 T 80.3 33.3 NA NA NA
2n3y 1 P99999 99.04 7e-73 NMR
 2016-12-14 GLY A:41 A:41 9.0 0.12 S 74.3 22.6 9.0 0.12 0.0 MH0
 3.377
 H
 O1A
3zoo 1 P99999 99.04 7e-73 X-RAY
 2013-10-23 GLY A:41 A:41 9.0 0.12 T 74.1 33.3 9.0 0.12 0.0 HEC
HOH
 2.935
2.680
 N
O
 O2A
O
GLY B:41 B:41 2.0 0.027 T 77.2 33.7 NA NA NA
GLY C:41 C:41 2.0 0.027 T 79.5 32.3 NA NA NA
GLY D:41 D:41 1.0 0.013 T 76.2 30.1 NA NA NA
5ty3 1 P99999 99.04 9e-73 X-RAY
 2017-09-06 GLY A:41 A:41 6.0 0.08 T 78.6 33.8 6.0 0.08 0.0 HEC
HOH
 2.078
2.692
 H
O
 O2A
O
GLY B:41 B:41 7.0 0.093 T 79.9 33.6 NA NA NA
6xnk 1 P99999 99.04 9e-73 X-RAY
 2021-07-07 GLY A:41 A:41 11.0 0.147 T 73.5 27.3 11.0 0.147 0.0 HEC
HOH
 2.069
3.190
 H
H
 O2A
O
GLY B:41 C:41 10.0 0.133 T 74.1 28.4 10.0 0.133 0.0 HEC
HOH
 2.238
3.413
 H
H
 O2A
O
GLY C:41 E:41 8.0 0.107 T 70.4 29.1 NA NA NA
GLY D:41 G:41 9.0 0.12 T 73.5 27.8 NA NA NA
3nwv 1 P99999 99.04 1e-72 X-RAY
 2011-03-09 SER A:41 A:41 23.0 0.2 T 68.3 28.0 23.0 0.2 0.0 HEC
HOH
 3.119
2.509
 N
OG
 O2A
O
SER B:41 B:41 23.0 0.2 T 69.8 28.1 NA NA NA
SER C:41 C:41 22.0 0.191 T 74.9 22.5 NA NA NA
SER D:41 D:41 23.0 0.2 T 72.9 23.3 NA NA NA
5exq 1 P99999 99.04 1e-72 X-RAY
 2016-11-30 GLY A:41 A:41 7.0 0.093 T 75.0 32.5 7.0 0.093 0.0 HEC
HOH
 2.755
2.577
 N
O
 O2A
O
GLY B:41 B:41 5.0 0.067 T 72.8 32.8 NA NA NA
5o10 1 P99999 99.04 1e-72 X-RAY
 2018-03-28 GLY A:41 A:41 7.0 0.093 T 69.5 38.2 7.0 0.093 0.0 HEC
HOH
 2.834
2.675
 N
O
 O2A
O
GLY B:41 B:41 6.0 0.08 T 72.8 37.3 6.0 0.08 0.0 HEC
HOH
 2.819
2.638
 N
O
 O2A
O
6duj 1 P99999 99.04 1e-72 X-RAY
 2019-06-26 GLY A:41 A:41 2.0 0.027 T 78.5 28.2 2.0 0.027 0.0 HEC
HOH
 2.261
3.206
 H
H
 O2A
O
GLY B:41 C:41 3.0 0.04 T 79.0 24.4 NA NA NA
6ecj 1 P99999 99.04 2e-72 X-RAY
 2019-08-14 THR A:41 A:41 20.0 0.143 T 65.2 37.5 20.0 0.143 0.0 HEC
HOH
 3.692
3.581
 N
N
 O2A
O
THR B:41 B:41 26.0 0.186 S 65.6 37.0 NA NA NA
THR C:41 C:41 31.0 0.221 S 66.6 37.3 NA NA NA
THR D:41 D:41 41.0 0.293 T 64.8 37.4 NA NA NA
THR E:41 E:41 32.0 0.229 S 66.0 37.1 NA NA NA
THR F:41 F:41 31.0 0.221 S 65.7 37.3 NA NA NA
THR G:41 G:41 30.0 0.214 S 66.2 37.9 NA NA NA
THR H:41 H:41 28.0 0.2 S 65.6 38.1 NA NA NA
5dfs 1 P00003 95.24 3e-71 X-RAY
 2016-03-02 GLY A:42 A:41 12.0 0.16 T 82.5 27.1 12.0 0.16 0.0 HEC
HOH
 2.237
2.844
 H
O
 O1A
O
GLY B:42 B:41 12.0 0.16 T 82.6 22.6 NA NA NA
5c0z 1 P62898 91.43 7e-68 X-RAY
 2016-09-21 GLY A:42 A:41 1.0 0.013 T 75.1 32.0 1.0 0.013 0.0 HEC
HOH
 2.974
3.525
 N
N
 O2A
O
GLY B:42 B:41 2.0 0.027 T 78.9 24.2 NA NA NA
GLY C:42 C:41 2.0 0.027 T 74.2 31.2 NA NA NA
GLY D:42 D:41 2.0 0.027 T 78.4 28.1 NA NA NA
5c9m 1 P62898 90.48 3e-67 X-RAY
 2016-09-21 GLY A:42 A:41 1.0 0.013 T 78.9 28.3 1.0 0.013 0.0 HEC
HOH
 3.004
3.498
 N
N
 O2A
O
GLY B:42 B:41 2.0 0.027 T 82.6 25.5 NA NA NA
GLY C:42 C:41 2.0 0.027 T 77.5 26.9 NA NA NA
GLY D:42 D:41 1.0 0.013 T 74.1 32.8 NA NA NA
7ljx 1 P62898 90.38 1e-66 X-RAY
 2021-05-12 GLY A:41 A:41 4.0 0.053 T 72.1 24.2 4.0 0.053 0.0 HEC
HOH
 3.023
4.397
 N
O
 O2A
O
GLY B:41 B:41 6.0 0.08 T 69.7 28.3 NA NA NA
2b4z 1 P62894 90.38 2e-66 X-RAY
 2005-10-11 GLY A:41 A:41 6.0 0.08 T 57.7 40.6 6.0 0.08 0.0 HEM
HOH
 2.843
2.726
 N
O
 O1A
O
2ybb 33 P62894 90.38 2e-66 EM
 2011-10-19 GLY GA:41 Y:41 7.0 0.093 T 57.7 40.6 7.0 0.093 0.0 HEM
HOH
 2.842
2.726
 N
O
 O2A
O
3j2t 2 P62894 90.38 2e-66 EM
 2013-04-10 GLY H:41 H:41 7.0 0.093 T 57.6 40.7 7.0 0.093 0.0 HEM
 2.842
 N
 O1A
GLY I:41 I:41 7.0 0.093 T 57.6 40.7 7.0 0.093 0.0 HEM
 2.843
 N
 O1A
GLY J:41 J:41 7.0 0.093 T 57.6 40.8 7.0 0.093 0.0 HEM
 2.842
 N
 O1A
GLY K:41 K:41 7.0 0.093 T 57.6 40.8 7.0 0.093 0.0 HEM
 2.843
 N
 O1A
GLY L:41 L:41 7.0 0.093 T 57.6 40.7 7.0 0.093 0.0 HEM
 2.842
 N
 O1A
GLY M:41 M:41 7.0 0.093 T 57.7 40.7 7.0 0.093 0.0 HEM
 2.842
 N
 O1A
GLY N:41 N:41 6.0 0.08 T 57.7 40.7 6.0 0.08 0.0 HEM
 2.843
 N
 O1A
5juy 2 P62894 90.38 2e-66 EM
 2016-10-19 GLY H:41 H:41 8.0 0.107 T 64.6 34.9 8.0 0.107 0.0 HEC
 3.228
 N
 O1A
GLY I:41 I:41 8.0 0.107 T 64.5 35.0 8.0 0.107 0.0 HEC
 3.228
 N
 O1A
GLY J:41 J:41 8.0 0.107 T 64.6 34.9 8.0 0.107 0.0 HEC
 3.229
 N
 O1A
GLY K:41 K:41 8.0 0.107 T 64.5 35.0 8.0 0.107 0.0 HEC
 3.230
 N
 O1A
GLY L:41 L:41 9.0 0.12 T 64.6 34.9 9.0 0.12 0.0 HEC
 3.229
 N
 O1A
GLY M:41 M:41 9.0 0.12 T 64.6 34.9 9.0 0.12 0.0 HEC
 3.229
 N
 O1A
GLY N:41 N:41 9.0 0.12 T 64.6 34.9 9.0 0.12 0.0 HEC
 3.229
 N
 O1A
6ff5 1 P62894 90.38 2e-66 X-RAY
 2018-03-21 GLY A:41 A:41 9.0 0.12 T 81.2 28.3 9.0 0.12 0.0 HEC
HOH
 2.977
3.430
 N
N
 O1A
O
6n1o 1 P62898 90.38 4e-66 X-RAY
 2019-10-23 GLY A:41 A:41 13.0 0.173 T 75.8 31.1 13.0 0.173 0.0 HEC
EDO
HOH
 3.083
7.014
2.856
 N
C
O
 O2A
O2
O
GLY B:41 B:41 5.0 0.067 T 71.9 31.8 NA NA NA
GLY C:41 C:41 2.0 0.027 T 75.5 31.8 NA NA NA
GLY D:41 D:41 3.0 0.04 T 74.0 30.7 NA NA NA
3jbt 2 P00004 88.57 4e-66 EM
 2015-11-18 GLY B:42 B:41 8.0 0.107 T 74.7 29.5 8.0 0.107 0.0 HEM
 3.139
 N
 O2A
GLY D:42 D:41 8.0 0.107 T 74.7 29.5 8.0 0.107 0.0 HEM
 3.138
 N
 O2A
GLY F:42 F:41 8.0 0.107 T 74.7 29.5 8.0 0.107 0.0 HEM
 3.138
 N
 O2A
GLY H:42 H:41 8.0 0.107 T 74.7 29.5 8.0 0.107 0.0 HEM
 3.139
 N
 O2A
GLY J:42 J:41 8.0 0.107 T 74.7 29.5 8.0 0.107 0.0 HEM
 3.138
 N
 O2A
GLY L:42 L:41 8.0 0.107 T 74.7 29.5 8.0 0.107 0.0 HEM
 3.139
 N
 O2A
GLY N:42 N:41 8.0 0.107 T 74.7 29.5 8.0 0.107 0.0 HEM
 3.138
 N
 O2A
5wve 2 P00004 88.57 4e-66 EM
 2017-02-08 GLY B:42 B:41 8.0 0.107 T 74.7 29.5 8.0 0.107 0.0 HEM
 3.139
 N
 O2A
GLY D:42 D:41 8.0 0.107 T 74.7 29.4 8.0 0.107 0.0 HEM
 3.139
 N
 O2A
GLY F:42 F:41 9.0 0.12 T 74.6 29.6 9.0 0.12 0.0 HEM
 3.139
 N
 O2A
GLY H:42 H:41 8.0 0.107 T 74.7 29.4 8.0 0.107 0.0 HEM
 3.138
 N
 O2A
GLY J:42 J:41 8.0 0.107 T 74.8 29.5 8.0 0.107 0.0 HEM
 3.140
 N
 O2A
GLY L:42 L:41 8.0 0.107 T 74.6 29.5 8.0 0.107 0.0 HEM
 3.138
 N
 O2A
GLY N:42 N:41 8.0 0.107 T 74.7 29.5 8.0 0.107 0.0 HEM
 3.139
 N
 O2A
5df5 1 P62898 90.38 5e-66 X-RAY
 2016-09-14 GLY A:41 A:41 9.0 0.12 T 75.7 32.5 9.0 0.12 0.0 HEC
HOH
 2.966
2.831
 N
O
 O2A
O
GLY B:41 B:41 2.0 0.027 T 71.6 34.8 NA NA NA
GLY C:41 C:41 1.0 0.013 T 76.4 28.7 NA NA NA
GLY D:41 D:41 1.0 0.013 T 76.4 26.3 NA NA NA
1ocd 1 P00004 88.46 3e-65 NMR
 1997-06-16 GLY A:41 A:41 13.0 0.173 S -65.6 84.4 13.0 0.173 0.0 HEC
HOH
 3.438
4.181
 HA2
C
 O2A
O
1u75 2 P00004 88.46 3e-65 X-RAY
 2004-09-28 GLY B:41 B:41 3.0 0.04 T 69.0 28.9 3.0 0.04 0.0 HEC
 2.694
 N
 O2A
2frc 1 P00004 88.46 3e-65 NMR
 1997-07-29 GLY A:41 A:41 5.0 0.067 T -167.8 70.5 5.0 0.067 0.0 HEC
HOH
 2.223
6.124
 HA2
HA2
 O1A
O
2n3b 1 P00004 88.46 3e-65 NMR
 2015-10-28 GLY A:41 A:41 14.0 0.187 T 47.2 51.2 14.0 0.187 0.0 HEC
HOH
 2.738
6.516
 H
HA2
 O2A
H2
2pcb 2 P00004 88.46 3e-65 X-RAY
 1993-07-15 GLY B:41 B:41 16.0 0.213 T 58.7 37.9 16.0 0.213 0.0 HEM
HOH
 2.575
6.304
 N
C
 O2A
O
3nbs 1 P00004 88.46 3e-65 X-RAY
 2010-07-14 GLY A:41 A:41 9.0 0.12 T 54.6 52.2 9.0 0.12 0.0 HEC
HOH
 2.965
2.783
 N
O
 O2A
O
GLY B:41 B:41 13.0 0.173 S 59.8 42.3 13.0 0.173 0.0 HEC
HOH
 3.069
3.307
 N
N
 O2A
O
GLY C:41 C:41 12.0 0.16 T 63.2 41.1 NA NA NA
GLY D:41 D:41 12.0 0.16 T 60.1 30.6 NA NA NA
3nbt 1 P00004 88.46 3e-65 X-RAY
 2010-07-14 GLY A:41 A:41 9.0 0.12 T 51.6 42.0 9.0 0.12 0.0 HEC
HOH
 2.759
3.326
 N
N
 O2A
O
GLY B:41 B:41 2.0 0.027 T 59.6 35.7 NA NA NA
GLY C:41 C:41 2.0 0.027 T 58.1 49.8 NA NA NA
GLY D:41 D:41 5.0 0.067 T 61.6 45.2 NA NA NA
GLY E:41 E:41 8.0 0.107 T 55.5 40.0 8.0 0.107 0.0 HEC
HOH
 2.894
4.086
 N
O
 O2A
O
GLY F:41 F:41 9.0 0.12 T 59.5 43.6 9.0 0.12 0.0 HEC
HOH
 2.923
5.213
 N
O
 O2A
O
3wc8 1 P00004 88.46 3e-65 X-RAY
 2013-12-11 GLY A:41 A:41 20.0 0.267 T 78.0 28.8 20.0 0.267 0.0 HEC
PEG
HOH
 2.907
9.937
3.121
 N
C
O
 O2A
C3
O
3wui 1 P00004 88.46 3e-65 X-RAY
 2014-07-16 GLY A:41 A:41 7.0 0.093 T 73.3 34.2 7.0 0.093 0.0 HEC
HOH
 2.879
3.402
 N
N
 O2A
O
4rsz 1 P00004 88.46 3e-65 X-RAY
 2015-01-14 GLY A:41 A:41 11.0 0.147 T 74.7 29.5 11.0 0.147 0.0 HEC
HOH
 3.096
3.278
 N
N
 O2A
O
GLY B:41 B:41 8.0 0.107 T 78.4 30.0 NA NA NA
GLY C:41 C:41 8.0 0.107 T 76.6 29.4 NA NA NA
GLY D:41 D:41 8.0 0.107 T 78.1 29.6 NA NA NA
GLY E:41 E:41 11.0 0.147 T 72.2 30.7 NA NA NA
GLY F:41 F:41 9.0 0.12 T 76.5 29.9 NA NA NA
6suv 1 P00004 88.46 3e-65 X-RAY
 2020-07-22 GLY A:41 AaA:41 5.0 0.067 T 78.2 32.0 5.0 0.067 0.0 HEC
HOH
 2.705
3.673
 N
N
 O2A
O
GLY B:41 BaB:41 11.0 0.147 T 78.2 32.2 NA NA NA
GLY C:41 CaC:41 5.0 0.067 T 78.0 32.6 NA NA NA
GLY D:41 DaD:41 10.0 0.133 T 78.0 32.0 NA NA NA
GLY E:41 EaE:41 10.0 0.133 T 78.3 31.5 NA NA NA
GLY F:41 FaF:41 9.0 0.12 T 77.8 32.1 NA NA NA
GLY G:41 GaG:41 11.0 0.147 T 78.4 32.0 NA NA NA
GLY H:41 HaH:41 10.0 0.133 T 77.6 33.0 NA NA NA
1crc 1 P00004 88.46 3e-65 X-RAY
 1996-03-08 GLY A:42 A:41 17.0 0.227 T 63.3 24.5 17.0 0.227 0.0 HEC
HOH
 2.803
3.666
 N
N
 O2A
O
GLY B:42 B:41 16.0 0.213 S 61.9 61.9 NA NA NA
1hrc 1 P00004 88.46 3e-65 X-RAY
 1994-11-01 GLY A:42 A:41 8.0 0.107 T 60.9 43.1 8.0 0.107 0.0 HEC
HOH
 3.178
4.071
 N
N
 O2A
O
1wej 3 P00004 88.46 3e-65 X-RAY
 1998-12-09 GLY C:42 F:41 1.0 0.013 T 64.2 37.1 1.0 0.013 0.0 HEM
HOH
 2.961
3.414
 N
N
 O2A
O
3o1y 1 P00004 88.46 3e-65 X-RAY
 2012-01-25 GLY A:42 A:41 12.0 0.16 T 75.8 26.5 12.0 0.16 0.0 HEC
HOH
 2.946
3.564
 N
N
 O2A
O
GLY B:42 B:41 1.0 0.013 T 78.6 22.9 NA NA NA
GLY C:42 C:41 2.0 0.027 T 75.3 28.2 NA NA NA
3o20 1 P00004 88.46 3e-65 X-RAY
 2012-01-25 GLY A:42 A:41 15.0 0.2 T 65.7 32.3 15.0 0.2 0.0 HEC
HOH
 3.187
2.516
 N
O
 O2A
O
GLY B:42 B:41 13.0 0.173 S 64.4 34.5 NA NA NA
GLY C:42 C:41 13.0 0.173 T 64.9 32.4 NA NA NA
5iy5 14 P00004 88.46 3e-65 X-RAY
 2017-01-11 GLY AA:42 1:41 16.0 0.213 S 75.0 31.6 16.0 0.213 0.0 HEC
HOH
 2.852
7.641
 N
N
 O2A
O
GLY BA:42 2:41 20.0 0.267 S -178.3 36.9 NA NA NA
6k9i 1 P00004 88.46 3e-65 X-RAY
 2020-06-17 GLY A:42 A:41 9.0 0.12 T 76.9 36.5 9.0 0.12 0.0 HEC
HOH
 2.935
3.546
 N
N
 O2A
O
6k9j 1 P00004 88.46 3e-65 X-RAY
 2020-06-17 GLY A:42 A:41 11.0 0.147 T 78.8 29.0 11.0 0.147 0.0 HEC
HOH
 2.949
2.619
 N
O
 O2A
O
5zkv 1 P00004 87.5 6e-64 NMR
 2019-05-22 GLY A:41 A:41 3.0 0.04 S 52.4 37.1 3.0 0.04 0.0 HEC
 2.627
 H
 O2A
4nfg 2 P00004 85.58 5e-63 X-RAY
 2014-09-24 GLY B:41 B:41 2.0 0.027 T 76.9 28.3 2.0 0.027 0.0 HEC
HOH
 3.104
3.601
 N
N
 O2A
O
2aiu 1 P00015 83.65 2e-62 X-RAY
 2006-07-18 GLY A:42 A:42 13.0 0.173 S 65.8 42.5 13.0 0.173 0.0 HEM
HOH
 2.834
2.707
 N
O
 O2A
O
1cyc 1 P00025 80.58 3e-58 X-RAY
 1976-10-06 GLY A:41 A:41 6.0 0.08 S 145.7 -155.0 6.0 0.08 0.0 HEC
HOH
 4.383
7.115
 N
N
 O2A
O
GLY B:41 B:41 6.0 0.08 S 145.7 -155.0 NA NA NA
1i54 1 P81459 80.58 3e-58 X-RAY
 2001-05-09 GLY A:41 A:41 10.0 0.133 T 64.2 44.6 10.0 0.133 0.0 HEC
ZNH
HOH
 2.902
2.905
2.295
 N
N
O
 O2A
O2A
O
GLY B:41 B:41 8.0 0.107 T 65.4 44.5 NA NA NA
1i55 1 P81459 80.58 3e-58 X-RAY
 2001-05-09 GLY A:41 A:41 9.0 0.12 T 58.7 49.0 9.0 0.12 0.0 HEC
ZNH
HOH
 2.862
2.835
2.371
 N
N
O
 O2A
O2A
O
GLY B:41 B:41 8.0 0.107 T 62.1 46.2 NA NA NA
1lfm 1 P81459 80.58 3e-58 X-RAY
 2002-07-19 GLY A:41 A:41 7.0 0.093 T 66.6 38.4 7.0 0.093 0.0 COH
HOH
 2.900
2.995
 N
O
 O2A
O
GLY B:41 B:41 6.0 0.08 T 66.8 36.9 NA NA NA
3cyt 1 P81459 80.58 3e-58 X-RAY
 1980-09-16 GLY A:42 O:41 8.0 0.107 T 77.3 24.3 8.0 0.107 0.0 HEC
HOH
 3.131
2.445
 N
O
 O2A
O
GLY B:42 I:41 10.0 0.133 T 80.1 29.6 NA NA NA
5cyt 1 P81459 80.58 3e-58 X-RAY
 1989-07-12 GLY A:42 R:41 15.0 0.2 T 71.5 26.4 15.0 0.2 0.0 HEC
HOH
 3.301
3.427
 N
N
 O2A
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p99999-f1 1 P99999 100.0 1e-74 GLY A:42 A:42 9.0 0.12 T 70.4 24.2