Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55210044 . C A CCDS5514.1:NM_005228.3:c.154Cag>Aag_NP_005219.2:p.52Q>K Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 GLN A:52 A:28 66.0 0.367 H -80.9 -27.7 66.0 0.367 0.0
GLN C:52 B:28 70.0 0.389 H -67.7 -39.5 70.0 0.389 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 GLN A:52 A:28 68.0 0.378 H -74.5 -43.1 68.0 0.378 0.0
GLN B:52 B:28 69.0 0.383 H -64.9 -24.1 69.0 0.383 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 GLN A:52 A:28 74.0 0.411 H -57.2 -61.2 74.0 0.411 0.0
GLN C:52 B:28 49.0 0.272 H -86.0 -28.8 49.0 0.272 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 GLN A:52 A:28 75.0 0.417 H -66.2 -31.3 75.0 0.417 0.0
GLN C:52 B:28 59.0 0.328 H -61.6 -34.2 59.0 0.328 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 GLN A:52 A:28 63.0 0.35 H -77.5 -45.1 63.0 0.35 0.0
GLN C:52 B:28 78.0 0.433 H -66.7 -35.5 78.0 0.433 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 GLN A:52 A:28 72.0 0.4 H -64.6 -61.4 72.0 0.4 0.0
GLN C:52 B:28 68.0 0.378 H -81.9 -14.2 68.0 0.378 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 GLN A:52 A:28 74.0 0.411 H -70.2 -38.6 74.0 0.411 0.0 NAG
ZN
 2.379
9.880
 NE2
OE1
 O7
ZN
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 GLN A:52 A:28 67.0 0.372 H -55.9 -46.3 67.0 0.372 0.0 NAG
NAG
FUC
HOH
 3.298
9.811
7.112
5.757
 OE1
OE1
O
NE2
 C8
O6
C6
O
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 GLN A:28 A:28 70.0 0.389 H -75.6 -47.6 70.0 0.389 0.0 NAG
HOH
 3.815
3.548
 NE2
NE2
 O5
O
GLN B:28 B:28 58.0 0.322 H -85.9 -47.3 58.0 0.322 0.0 NAG
HOH
 4.038
2.773
 OE1
NE2
 C1
O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 GLN A:28 A:28 76.0 0.422 H -50.0 -47.8 76.0 0.422 0.0
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 GLN C:28 NA:NA DO NA DO DO DO NA NA NA
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 GLN A:28 A:28 24.0 NA H -60.5 -48.7 24.0 NA NA
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 GLN A:28 A:28 72.0 0.4 H -57.3 -61.3 72.0 0.4 0.0 NAG
 3.614
 OE1
 C8
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 GLN A:28 A:28 87.0 0.483 H -71.7 -46.2 87.0 0.483 0.0
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 GLN A:28 A:28 71.0 0.394 H -56.7 -44.1 71.0 0.394 0.0 NAG
HOH
 3.978
9.851
 OE1
N
 O6
O
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 GLN A:28 A:28 68.0 0.378 H -56.6 -46.6 68.0 0.378 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 GLN A:28 A:28 74.0 0.411 H -66.2 -46.5 74.0 0.411 0.0 NAG
NAG
 3.001
6.652
 OE1
NE2
 C8
C8
GLN B:28 B:28 65.0 0.361 H -80.0 -38.1 65.0 0.361 0.0 NAG
 3.651
 CD
 O7
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 GLN A:27 A:28 66.0 0.367 H -60.0 -23.9 66.0 0.367 0.0 HOH
 5.758
 NE2
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 GLN A:28 A:28 75.0 0.417 H -58.9 -47.6 75.0 0.417 0.0 NAG
 3.520
 OE1
 C8
GLN B:28 B:28 71.0 0.394 H -59.9 -46.0 NA NA NA
GLN C:28 C:28 69.0 0.383 H -62.2 -37.7 NA NA NA
GLN D:28 D:28 77.0 0.428 H -58.5 -59.2 77.0 0.428 0.0 NAG
 4.580
 OE1
 C8
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 GLN A:28 A:28 71.0 0.394 H -60.2 -43.3 71.0 0.394 0.0 NAG
NAG
HOH
 4.098
8.341
7.261
 OE1
NE2
O
 C8
O5
O
GLN D:28 D:28 68.0 0.378 H -66.4 -36.6 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 GLN A:28 A:28 70.0 0.389 H -55.2 -31.8 70.0 0.389 0.0 NAG
PT
HOH
 3.497
8.396
8.576
 CG
C
O
 O7
PT
O
GLN B:28 B:28 74.0 0.411 H -60.8 -31.1 74.0 0.411 0.0 NAG
PT
HOH
 4.762
9.005
7.385
 O
N
N
 O7
PT
O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLN A:28 A:28 74.0 0.411 H -71.1 -40.8 74.0 0.411 0.0
GLN B:28 B:28 78.0 0.433 H -75.3 -36.2 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLN A:28 A:28 79.0 0.439 H -58.6 -46.7 79.0 0.439 0.0
GLN B:28 B:28 72.0 0.4 H -62.8 -47.0 72.0 0.4 0.0 NAG
 3.497
 CD
 C8
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLN A:28 A:28 71.0 0.394 H -69.6 -32.6 71.0 0.394 0.0 NAG
 4.274
 NE2
 C8
GLN B:28 B:28 75.0 0.417 H -65.3 -42.1 NA NA NA
GLN C:28 C:28 72.0 0.4 H -59.3 -46.9 NA NA NA
GLN D:28 D:28 82.0 0.456 H -61.6 -49.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 GLN A:52 A:52 68.0 0.378 H -63.1 -50.0