Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55211080 . G A CCDS5514.1:NM_005228.3:c.323aGa>aAa_NP_005219.2:p.108R>K Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:108 A:84 39.0 0.173 -70.3 -22.5 39.0 0.173 0.0
ARG C:108 B:84 51.0 0.227 -66.5 -31.0 51.0 0.227 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:108 A:84 41.0 0.182 -62.8 -22.6 41.0 0.182 0.0
ARG B:108 B:84 45.0 0.2 -58.6 -20.8 45.0 0.2 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:108 A:84 44.0 0.196 -58.2 -19.7 44.0 0.196 0.0
ARG C:108 B:84 49.0 0.218 -64.8 -49.0 49.0 0.218 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 ARG A:108 A:84 48.0 0.213 -61.2 -21.8 48.0 0.213 0.0
ARG C:108 B:84 49.0 0.218 -61.9 -11.5 49.0 0.218 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 ARG A:108 A:84 38.0 0.169 -72.6 -5.3 38.0 0.169 0.0
ARG C:108 B:84 37.0 0.164 -29.4 -46.1 37.0 0.164 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 ARG A:108 A:84 54.0 0.24 -65.6 -10.2 54.0 0.24 0.0
ARG C:108 B:84 45.0 0.2 -76.4 85.3 45.0 0.2 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 ARG A:108 A:84 14.0 0.062 -66.8 -32.1 14.0 0.062 0.0 ZN
 7.068
 O
 ZN
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 ARG A:108 A:84 13.0 0.058 -75.8 -19.5 13.0 0.058 0.0
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 ARG A:84 A:84 41.0 0.182 -49.7 -45.5 41.0 0.182 0.0 HOH
 7.626
 O
 O
ARG B:84 B:84 50.0 0.222 -53.8 -59.9 50.0 0.222 0.0 HOH
 6.021
 NH2
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 ARG A:84 A:84 14.0 0.062 -80.7 -23.2 14.0 0.062 0.0 HOH
 4.201
 CD
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 ARG C:84 NA:NA DO NA DO DO DO NA NA NA
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 ARG A:84 A:84 21.0 NA -71.6 -41.0 21.0 NA NA
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 ARG A:84 A:84 13.0 0.058 -79.7 -28.1 13.0 0.058 0.0
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 ARG A:84 A:84 25.0 NA -71.6 -36.5 25.0 NA NA
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 ARG A:84 A:84 13.0 0.058 -73.3 -38.1 13.0 0.058 0.0
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 ARG A:84 A:84 11.0 0.049 -74.5 -18.5 11.0 0.049 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 ARG A:84 A:84 43.0 0.191 -72.7 -31.8 43.0 0.191 0.0 HOH
 6.129
 O
 O
ARG B:84 B:84 41.0 0.182 -58.6 -54.4 41.0 0.182 0.0 HOH
 6.756
 O
 O
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 ARG A:83 A:84 22.0 0.098 -71.6 -38.1 22.0 0.098 0.0 HOH
 9.320
 CD
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 ARG A:84 A:84 24.0 0.107 -74.8 -31.8 24.0 0.107 0.0
ARG B:84 B:84 34.0 0.151 -75.2 -28.7 NA NA NA
ARG C:84 C:84 14.0 0.062 -81.8 -36.1 NA NA NA
ARG D:84 D:84 15.0 0.067 -72.9 -44.3 15.0 0.067 0.0
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 ARG A:84 A:84 11.0 0.049 -67.6 -27.4 11.0 0.049 0.0 HOH
 2.438
 NE
 O
ARG D:84 D:84 13.0 0.058 -66.0 -30.5 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 ARG A:84 A:84 34.0 0.151 -62.9 -48.9 34.0 0.151 0.0 HOH
 6.623
 O
 O
ARG B:84 B:84 35.0 0.156 -56.3 -41.2 35.0 0.156 0.0 HOH
 3.208
 NH2
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 LYS A:84 A:84 40.0 0.2 -73.0 -21.2 40.0 0.2 0.0
LYS B:84 B:84 29.0 0.145 -63.3 -40.2 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 LYS A:84 A:84 32.0 0.16 -81.1 -13.8 32.0 0.16 0.0
LYS B:84 B:84 23.0 0.115 -67.2 -32.9 23.0 0.115 0.0
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ARG A:84 A:84 21.0 0.093 -69.0 -26.9 21.0 0.093 0.0
ARG B:84 B:84 25.0 0.111 -69.4 -30.3 NA NA NA
ARG C:84 C:84 11.0 0.049 -67.9 -28.5 NA NA NA
ARG D:84 D:84 12.0 NA -65.3 -33.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 ARG A:108 A:108 16.0 0.071 -79.0 -31.9