Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55229225 . C A CCDS5514.1:NM_005228.3:c.1532tCc>tAc_NP_005219.2:p.511S>Y Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 SER A:511 A:487 30.0 0.261 -65.8 159.4 30.0 0.261 0.0
SER C:511 B:487 30.0 0.261 -62.9 157.6 30.0 0.261 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 SER A:511 A:487 15.0 0.13 -60.0 159.0 15.0 0.13 0.0
SER B:511 B:487 0.0 0.0 53.0 76.2 0.0 0.0 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 SER A:511 A:487 21.0 0.183 -65.5 163.2 21.0 0.183 0.0
SER C:511 B:487 66.0 0.574 -94.9 153.0 66.0 0.574 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 SER A:511 A:487 23.0 0.2 -60.9 158.8 23.0 0.2 0.0
SER C:511 B:487 17.0 0.148 -42.7 142.9 17.0 0.148 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 SER A:511 A:487 28.0 0.243 -106.3 166.9 28.0 0.243 0.0
SER C:511 B:487 13.0 0.113 -59.1 144.7 13.0 0.113 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 SER A:511 A:487 17.0 0.148 -60.7 156.1 17.0 0.148 0.0
SER C:511 B:487 33.0 0.287 -54.9 116.8 33.0 0.287 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 SER A:511 A:487 11.0 0.096 -74.8 164.6 11.0 0.096 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 SER A:511 A:487 16.0 0.139 -77.4 162.4 16.0 0.139 0.0 NAG
FUC
 8.800
8.276
 N
CA
 C6
C6
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 SER A:487 A:487 23.0 0.2 176.0 -178.0 23.0 0.2 0.0 HOH
 7.868
 N
 O
SER B:487 B:487 21.0 0.183 -44.9 169.9 21.0 0.183 0.0 HOH
 7.119
 O
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 SER A:487 A:487 19.0 0.165 -66.4 177.1 19.0 0.165 0.0 HOH
 2.823
 OG
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 SER C:487 A:487 15.0 0.13 -51.5 160.0 15.0 0.13 0.0 NAG
 8.771
 CA
 C8
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 SER A:487 A:487 17.0 0.148 -74.9 -178.5 17.0 0.148 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 SER A:487 A:487 16.0 0.139 -99.6 166.9 16.0 0.139 0.0 NAG
 8.639
 CA
 O6
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 SER A:487 A:487 13.0 0.113 -75.3 169.3 13.0 0.113 0.0 NAG
 6.961
 HA
 H61
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 SER A:487 A:487 16.0 0.139 -65.1 170.2 16.0 0.139 0.0 NAG
HOH
 6.183
7.493
 N
O
 O7
O
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 SER A:487 A:487 11.0 0.096 -76.5 162.5 11.0 0.096 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 SER A:487 A:487 26.0 0.226 -65.9 157.1 26.0 0.226 0.0
SER B:487 B:487 28.0 0.243 -54.7 152.4 28.0 0.243 0.0 NAG
 8.167
 CA
 C8
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 SER A:486 A:487 23.0 0.2 -65.8 168.5 23.0 0.2 0.0 NAG
HOH
 8.463
3.914
 CA
OG
 C6
O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 SER A:487 A:487 108.0 0.939 -115.7 11.9 108.0 0.939 0.0
SER B:487 B:487 84.0 0.73 -59.0 -32.1 NA NA NA
SER C:487 C:487 53.0 0.461 -66.9 -168.0 NA NA NA
SER D:487 D:487 73.0 0.635 -155.3 -156.2 73.0 0.635 0.0
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 SER A:487 A:487 34.0 0.296 B -108.2 159.5 34.0 0.296 0.0 HOH
 5.439
 N
 O
SER D:487 D:487 15.0 0.13 -81.4 171.0 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 SER A:487 A:487 125.0 1.0 -46.4 -27.1 125.0 1.0 0.0 HOH
 9.011
 N
 O
SER B:487 B:487 117.0 1.0 -20.7 -44.4 117.0 1.0 0.0 HOH
 2.774
 OG
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 SER A:487 A:487 101.0 0.878 -84.1 -34.4 101.0 0.878 0.0
SER B:487 B:487 58.0 0.504 B -117.1 171.5 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 SER A:487 A:487 78.0 0.678 -124.7 43.5 78.0 0.678 0.0
SER B:487 B:487 53.0 0.461 -72.4 167.4 53.0 0.461 0.0
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 SER A:487 A:487 118.0 1.0 -68.9 -53.7 118.0 1.0 0.0
SER B:487 B:487 80.0 0.696 -68.1 -41.7 NA NA NA
SER C:487 C:487 50.0 0.435 -66.5 175.9 NA NA NA
SER D:487 D:487 65.0 0.565 -82.7 157.4 NA NA NA
3p0y 1 P00533 99.52 3e-141 X-RAY
 2011-10-26 SER A:178 A:487 17.0 0.148 -67.6 172.2 17.0 0.148 0.0 HOH
 2.668
 O
 O
3b2u 3 P00533 99.51 2e-140 X-RAY
 2008-02-19 SER C:181 A:487 34.0 0.296 -84.1 174.7 34.0 0.296 0.0
SER F:181 B:487 32.0 0.278 -91.2 158.6 NA NA NA
SER I:181 E:487 27.0 0.235 -65.4 164.9 NA NA NA
SER L:181 I:487 20.0 0.174 -77.2 171.3 NA NA NA
SER O:181 M:487 26.0 0.226 -58.7 166.8 NA NA NA
SER R:181 P:487 18.0 0.157 -72.6 153.5 NA NA NA
SER U:181 S:487 23.0 0.2 -66.6 149.4 NA NA NA
SER X:181 V:487 27.0 0.235 -80.1 165.5 NA NA NA
3c09 3 P00533 99.51 2e-140 X-RAY
 2008-04-15 SER C:181 A:487 60.0 0.522 -97.1 171.4 NA NA NA
SER F:181 D:487 83.0 0.722 -69.0 98.6 83.0 0.722 0.0
4krl 2 P00533 99.51 2e-140 X-RAY
 2013-08-28 SER B:181 A:487 18.0 0.157 -77.7 178.5 18.0 0.157 0.0 MES
HOH
 4.189
6.720
 CB
O
 O1S
O
4krm 1 P00533 99.51 2e-140 X-RAY
 2013-08-28 SER A:181 A:487 18.0 0.157 -76.2 177.7 18.0 0.157 0.0
SER C:181 C:487 18.0 0.157 -75.6 173.0 NA NA NA
SER E:181 E:487 19.0 0.165 -78.7 179.1 NA NA NA
SER G:181 G:487 18.0 0.157 -74.2 176.8 NA NA NA
SER I:181 I:487 35.0 0.304 -75.0 167.7 NA NA NA
SER K:181 K:487 28.0 0.243 -72.3 173.3 NA NA NA
6b3s 1 P00533 99.02 1e-139 X-RAY
 2017-12-06 SER A:181 A:487 81.0 0.704 -102.9 168.2 81.0 0.704 0.0
SER D:181 B:487 40.0 0.348 -94.6 171.9 NA NA NA
SER G:181 E:487 29.0 0.252 -123.1 167.0 NA NA NA
SER J:181 I:487 31.0 0.27 -62.5 174.6 NA NA NA
5sx4 3 P00533 98.44 5e-129 X-RAY
 2016-10-05 SER E:181 M:487 28.0 0.243 -70.4 163.8 28.0 0.243 0.0
SER F:181 N:487 39.0 0.339 -87.9 151.9 NA NA NA
5sx5 3 P00533 97.92 3e-128 X-RAY
 2016-10-05 SER E:181 M:487 15.0 0.13 -79.3 154.5 15.0 0.13 0.0
SER F:181 N:487 19.0 0.165 -79.5 151.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 SER A:511 A:511 17.0 0.148 -74.1 172.1