Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55229230 . G A CCDS5514.1:NM_005228.3:c.1537Gag>Aag_NP_005219.2:p.513E>K Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 GLU A:513 A:489 86.0 0.453 T -106.8 -17.2 86.0 0.453 0.0
GLU C:513 B:489 63.0 0.332 T -59.8 -42.6 63.0 0.332 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 GLU A:513 A:489 65.0 0.342 T -63.6 -57.0 65.0 0.342 0.0
GLU B:513 B:489 114.0 0.6 S -71.6 68.0 114.0 0.6 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 GLU A:513 A:489 77.0 0.405 T -132.6 13.3 77.0 0.405 0.0
GLU C:513 B:489 108.0 0.568 T -133.4 1.1 108.0 0.568 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 GLU A:513 A:489 56.0 0.295 T -118.9 -43.9 56.0 0.295 0.0
GLU C:513 B:489 85.0 0.447 T -167.9 -52.9 85.0 0.447 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 GLU A:513 A:489 81.0 0.426 T -73.1 -39.2 81.0 0.426 0.0
GLU C:513 B:489 85.0 0.447 T -55.9 -26.4 85.0 0.447 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 GLU A:513 A:489 106.0 0.558 S -152.7 177.9 106.0 0.558 0.0
GLU C:513 B:489 72.0 0.379 S -141.7 -10.4 72.0 0.379 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 GLU A:513 A:489 62.0 0.326 T -84.6 9.2 62.0 0.326 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 GLU A:513 A:489 75.0 0.395 T -64.9 0.7 75.0 0.395 0.0
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 GLU A:489 A:489 42.0 0.221 S -65.5 106.7 42.0 0.221 0.0
GLU B:489 B:489 47.0 0.247 T -77.9 -46.6 47.0 0.247 0.0 HOH
 4.027
 O
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 GLU A:489 A:489 52.0 0.274 T -80.8 3.5 52.0 0.274 0.0 HOH
 2.613
 O
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 GLU C:489 A:489 99.0 0.521 S -72.0 -49.9 99.0 0.521 0.0
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 GLU A:489 A:489 89.0 0.468 T -81.6 -8.1 89.0 0.468 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 GLU A:489 A:489 106.0 0.558 T -52.9 -28.6 106.0 0.558 0.0
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 GLU A:489 A:489 66.0 0.347 T -67.0 -15.1 66.0 0.347 0.0
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 GLU A:489 A:489 66.0 0.347 T -93.3 -0.4 66.0 0.347 0.0 HOH
 8.731
 C
 O
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 GLU A:489 A:489 59.0 0.311 T -65.1 0.7 59.0 0.311 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 GLU A:489 A:489 49.0 0.258 T -58.2 -22.8 49.0 0.258 0.0
GLU B:489 B:489 52.0 0.274 T -60.7 -23.2 52.0 0.274 0.0
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 GLU A:488 A:489 41.0 0.216 T -102.9 1.6 36.0 0.189 0.027 B:E0ACT6+Q4G1L3:0.026
 HOH
 3.556
 OE1
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 GLU A:489 A:489 97.0 0.511 S -117.6 15.7 97.0 0.511 0.0
GLU B:489 B:489 145.0 0.763 S -52.1 117.9 NA NA NA
GLU C:489 C:489 65.0 0.342 T -72.9 -53.1 NA NA NA
GLU D:489 D:489 103.0 0.542 T -58.2 -27.6 103.0 0.542 0.0 HOH
 9.488
 OE2
 O
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 GLU A:489 A:489 53.0 0.279 T -70.3 -12.3 53.0 0.279 0.0 HOH
 9.195
 N
 O
GLU D:489 D:489 56.0 0.295 T -90.6 -4.9 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 GLU A:489 A:489 95.0 0.5 S -77.3 61.7 95.0 0.5 0.0 HOH
 9.124
 O
 O
GLU B:489 B:489 95.0 0.5 S -119.4 83.0 95.0 0.5 0.0 HOH
 8.878
 N
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLU A:489 A:489 57.0 0.3 S -109.8 19.7 57.0 0.3 0.0
GLU B:489 B:489 62.0 0.326 T -68.8 -15.3 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLU A:489 A:489 51.0 0.268 S -124.8 -21.5 51.0 0.268 0.0
GLU B:489 B:489 101.0 0.532 T -74.4 -23.9 101.0 0.532 0.0
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLU A:489 A:489 50.0 NA S 66.5 -4.4 50.0 NA NA
GLU B:489 B:489 125.0 0.658 S -71.2 109.0 NA NA NA
GLU C:489 C:489 84.0 0.442 T -119.3 1.4 NA NA NA
GLU D:489 D:489 114.0 0.6 T -56.7 -15.0 NA NA NA
3p0y 1 P00533 99.52 3e-141 X-RAY
 2011-10-26 GLU A:180 A:489 45.0 0.237 T -72.2 -9.2 45.0 0.237 0.0 HOH
 2.584
 O
 O
3b2u 3 P00533 99.51 2e-140 X-RAY
 2008-02-19 GLU C:183 A:489 30.0 NA T -76.6 -14.3 30.0 NA NA HOH
 9.880
 O
 O
GLU F:183 B:489 36.0 NA T -63.9 -37.9 NA NA NA
GLU I:183 E:489 37.0 NA T -85.9 3.0 NA NA NA
GLU L:183 I:489 82.0 0.432 T -90.7 -1.9 NA NA NA
GLU O:183 M:489 29.0 NA T -120.1 6.9 NA NA NA
GLU R:183 P:489 49.0 NA T -64.2 -7.1 NA NA NA
GLU U:183 S:489 45.0 NA T -88.0 27.1 NA NA NA
GLU X:183 V:489 35.0 NA T -66.0 -26.5 NA NA NA
3c09 3 P00533 99.51 2e-140 X-RAY
 2008-04-15 GLU C:183 A:489 38.0 NA T -62.9 -34.2 NA NA NA
GLU F:183 D:489 48.0 NA S -122.7 -25.2 48.0 NA NA
4krl 2 P00533 99.51 2e-140 X-RAY
 2013-08-28 GLU B:183 A:489 48.0 0.253 T -80.4 0.3 48.0 0.253 0.0 MES
HOH
 3.227
3.813
 OE1
C
 C3
O
4krm 1 P00533 99.51 2e-140 X-RAY
 2013-08-28 GLU A:183 A:489 63.0 0.332 T -83.9 -0.7 63.0 0.332 0.0 HOH
 8.421
 O
 O
GLU C:183 C:489 57.0 0.3 T -77.0 -0.0 NA NA NA
GLU E:183 E:489 58.0 0.305 T -85.0 -5.7 NA NA NA
GLU G:183 G:489 94.0 0.495 T -79.9 -4.5 NA NA NA
GLU I:183 I:489 73.0 0.384 T -68.3 -20.2 NA NA NA
GLU K:183 K:489 90.0 0.474 T -85.6 -2.7 NA NA NA
6b3s 1 P00533 99.02 1e-139 X-RAY
 2017-12-06 GLU A:183 A:489 49.0 NA T -54.5 -28.6 49.0 NA NA
GLU D:183 B:489 106.0 0.558 T -65.3 -18.5 NA NA NA
GLU G:183 E:489 73.0 0.384 T -65.8 -21.3 NA NA NA
GLU J:183 I:489 32.0 NA T -68.6 -33.8 NA NA NA
5sx4 3 P00533 98.44 5e-129 X-RAY
 2016-10-05 GLU E:183 M:489 46.0 0.242 T -105.2 -16.4 46.0 0.242 0.0 HOH
 9.814
 O
 O
GLU F:183 N:489 49.0 0.258 T -85.9 -20.9 NA NA NA
5sx5 3 P00533 97.92 3e-128 X-RAY
 2016-10-05 GLU E:183 M:489 44.0 0.232 T -79.4 -10.6 44.0 0.232 0.0
GLU F:183 N:489 64.0 0.337 T -66.9 -31.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 GLU A:513 A:513 41.0 0.216 T -80.0 -9.1