Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 6431665 . C A CCDS5348.1:NM_006908.4:c.218cCg>cAg_NP_008839.2:p.73P>Q Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1i4d 2 P63000 100.0 4e-143 X-RAY
 2001-05-16 PRO C:73 D:73 86.0 0.593 T -52.8 133.2 64.0 0.441 0.152 A:P53365:0.152
 HOH
 3.665
 O
 O
1i4l 2 P63000 100.0 4e-143 X-RAY
 2001-05-16 PRO C:73 D:73 73.0 0.503 T -59.5 142.1 45.0 0.31 0.193 A:P53365:0.193
 HOH
 3.283
 CG
 O
6tgc 3 P63000 100.0 4e-143 EM
 2020-07-29 PRO C:73 C:73 60.0 0.414 T -39.1 -36.2 31.0 0.214 0.2 A:Q92608:0.2
PRO F:73 F:73 61.0 0.421 T -39.1 -36.2 39.0 0.269 0.152 D:Q92608:0.152
5fi0 2 P63000 100.0 6e-143 X-RAY
 2016-04-20 PRO B:76 B:73 80.0 0.552 T -49.0 133.7 53.0 0.366 0.186 A:Q8TCU6:0.186
PRO D:76 D:73 78.0 0.538 T -48.3 134.9 NA NA NA
PRO F:76 F:73 82.0 0.566 T -48.1 135.8 NA NA NA
PRO H:76 H:73 76.0 0.524 T -48.6 134.4 NA NA NA
1i4t 2 P63000 99.48 7e-142 X-RAY
 2001-05-16 PRO C:73 D:73 70.0 0.483 T -48.1 141.2 40.0 0.276 0.207 A:P53365:0.207
 HOH
 3.369
 CG
 O
1e96 1 P15154 99.48 9e-141 X-RAY
 2000-11-17 PRO A:73 A:73 81.0 0.559 T -59.5 146.7 81.0 0.559 0.0 HOH
 9.636
 C
 O
1hh4 1 P15154 99.48 9e-141 X-RAY
 2001-08-28 PRO A:73 A:73 82.0 0.566 T -61.1 140.0 22.0 0.152 0.414 C:P52565:0.414
 HOH
 3.080
 CD
 O
PRO B:73 B:73 75.0 0.517 T -58.5 140.1 NA NA NA
2vrw 1 P63000 100.0 5e-137 X-RAY
 2008-06-17 PRO A:73 A:73 67.0 0.462 T -54.6 137.7 60.0 0.414 0.048 B:P27870:0.048
 HOH
 3.254
 CG
 O
1g4u 2 P63000 99.46 6e-136 X-RAY
 2001-01-24 PRO B:73 R:73 62.0 0.428 T -58.9 128.8 62.0 0.428 0.0 HOH
 3.247
 CD
 O
2h7v 1 P63000 99.46 7e-136 X-RAY
 2006-09-19 PRO A:77 A:73 77.0 0.531 T -48.1 133.6 50.0 0.345 0.186 C:Q05608:0.186
PRO B:77 B:73 73.0 0.503 T -47.5 142.0 NA NA NA
2p2l 1 P63000 99.46 7e-136 X-RAY
 2007-05-01 PRO A:77 A:73 81.0 0.559 T -67.9 -175.8 81.0 0.559 0.0 HOH
 3.331
 CG
 O
PRO B:77 B:73 83.0 0.572 T -68.8 -170.9 83.0 0.572 0.0 HOH
 3.135
 CG
 O
PRO C:77 C:73 81.0 0.559 T -68.1 -174.2 81.0 0.559 0.0 HOH
 3.303
 CG
 O
1mh1 1 P63000 99.45 9e-135 X-RAY
 1998-01-21 PRO A:75 A:73 61.0 0.421 T -53.5 138.2 61.0 0.421 0.0 HOH
 3.509
 N
 O
1ds6 1 P15153 92.19 3e-133 X-RAY
 2000-07-12 PRO A:73 A:73 69.0 0.476 T -52.4 135.6 17.0 0.117 0.359 B:P52566:0.359
 HOH
 3.583
 N
 O
2yin 2 P63000 100.0 6e-132 X-RAY
 2011-05-25 PRO C:92 C:73 90.0 0.621 T -59.2 -43.0 NA NA NA
PRO D:92 D:73 69.0 0.476 T -62.9 140.7 30.0 0.207 0.269 B:Q92608:0.269
 HOH
 3.950
 CG
 O
3su8 1 P63000 100.0 1e-131 X-RAY
 2011-09-28 PRO A:73 A:73 57.0 0.393 T -63.1 145.1 51.0 0.352 0.041 B:O43157:0.041
3sua 1 P63000 100.0 1e-131 X-RAY
 2011-09-07 PRO A:73 A:73 78.0 0.538 T -51.5 135.0 76.0 0.524 0.014 D:O43157:0.014
PRO B:73 B:73 78.0 0.538 T -52.0 135.0 NA NA NA
PRO C:73 C:73 81.0 0.559 T -51.9 134.4 NA NA NA
6x1g 2 P63000 100.0 1e-131 X-RAY
 2020-11-25 PRO C:73 B:73 61.0 0.421 T -54.2 139.6 49.0 0.338 0.083 A:B3CVM3:0.083
 HOH
 3.940
 CD
 O
PRO D:73 D:73 58.0 0.4 T -54.7 142.1 NA NA NA
2fju 1 P63000 100.0 1e-131 X-RAY
 2006-11-21 PRO A:73 A:73 65.0 0.448 T -45.7 131.3 65.0 0.448 0.0 HOH
 3.448
 N
 O
5qqd 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 56.0 0.386 T -50.3 133.6 39.0 0.269 0.117 B:O60229:0.117
 HOH
 3.226
 O
 O
5qqe 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 55.0 0.379 T -48.8 137.5 38.0 0.262 0.117 B:O60229:0.117
 HOH
 3.222
 O
 O
5qqf 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 52.0 0.359 T -51.5 142.8 38.0 0.262 0.097 B:O60229:0.097
 HOH
 3.057
 O
 O
5qqg 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 53.0 0.366 T -62.1 146.5 37.0 0.255 0.111 B:O60229:0.11
 HOH
 3.175
 CG
 O
5qqh 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 55.0 0.379 T -58.3 141.0 37.0 0.255 0.124 B:O60229:0.124
 HOH
 3.165
 O
 O
5qqi 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 55.0 0.379 T -56.7 139.1 38.0 0.262 0.117 B:O60229:0.117
 HOH
 3.104
 CG
 O
5qqj 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 55.0 0.379 T -52.4 136.2 36.0 0.248 0.131 B:O60229:0.131
 HOH
 3.037
 CG
 O
5qqk 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 53.0 0.366 T -62.7 145.6 35.0 0.241 0.125 B:O60229:0.124
 HOH
 3.031
 O
 O
5qql 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 56.0 0.386 T -51.2 142.3 39.0 0.269 0.117 B:O60229:0.117
 HOH
 3.193
 O
 O
5qqm 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 55.0 0.379 T -58.8 140.9 37.0 0.255 0.124 B:O60229:0.124
 HOH
 3.205
 CG
 O
5qqn 1 P63000 100.0 1e-131 X-RAY
 2019-12-18 PRO A:74 A:73 56.0 0.386 T -50.5 138.6 37.0 0.255 0.131 B:O60229:0.131
 HOH
 2.990
 O
 O
5qu9 1 P63000 100.0 1e-131 X-RAY
 2020-01-29 PRO A:74 A:73 63.0 0.434 T -56.6 140.4 40.0 0.276 0.158 B:O60229:0.159
 HOH
 3.145
 O
 O
1foe 2 P63000 100.0 2e-131 X-RAY
 2001-01-17 PRO B:73 B:73 75.0 0.517 T -53.6 146.4 45.0 0.31 0.207 A:Q60610:0.207
 HOH
 3.919
 C
 O
PRO D:73 D:73 74.0 0.51 T -56.2 145.8 NA NA NA
PRO F:73 F:73 75.0 0.517 T -54.8 145.8 NA NA NA
PRO H:73 H:73 77.0 0.531 T -55.4 144.3 NA NA NA
2nz8 1 P63000 100.0 2e-131 X-RAY
 2007-04-10 PRO A:73 A:73 79.0 0.545 T -53.8 141.6 43.0 0.297 0.248 B:O75962:0.248
 HOH
 3.599
 CA
 O
3bji 2 P63000 100.0 2e-131 X-RAY
 2008-07-15 PRO C:73 C:73 72.0 0.497 T -62.3 149.5 NA NA NA
PRO D:73 D:73 73.0 0.503 T -64.4 144.8 71.0 0.49 0.013 A:P15498:0.014
 HOH
 4.550
 O
 O
5o33 1 P63000 100.0 2e-131 X-RAY
 2017-05-31 PRO A:73 A:73 63.0 0.434 T -56.5 139.1 44.0 0.303 0.131 B:P97924:0.131
 HOH
 3.034
 O
 O
3b13 2 P63000 99.44 4e-131 X-RAY
 2012-03-14 PRO B:80 B:73 83.0 0.572 T -47.4 133.9 39.0 0.269 0.303 A:Q92608:0.303
PRO D:80 D:73 80.0 0.552 T -49.7 136.5 38.0 0.262 0.29 C:Q92608:0.29
7dpa 2 P63000 99.44 6e-131 EM
 2021-08-04 PRO B:80 B:73 67.0 0.462 S -57.1 139.1 67.0 0.462 0.0
PRO E:80 E:73 66.0 0.455 S -57.1 139.1 66.0 0.455 0.0
1ryf 1 P63000 90.55 6e-131 X-RAY
 2004-01-27 PRO A:75 NA:NA DO NA DO DO DO NA NA NA
PRO B:75 NA:NA DO NA DO DO DO NA NA NA
1ryh 1 P63000 90.55 6e-131 X-RAY
 2004-01-27 PRO A:75 NA:NA DO NA DO DO DO NA NA NA
PRO B:75 NA:NA DO NA DO DO DO NA NA NA
3th5 1 P63000 100.0 8e-131 X-RAY
 2012-07-18 PRO A:100 A:73 69.0 0.476 T -63.3 140.3 69.0 0.476 0.0
PRO B:100 B:73 66.0 0.455 T -57.5 142.9 NA NA NA
6bc1 1 P63000 100.0 1e-130 X-RAY
 2017-12-13 PRO A:73 A:73 69.0 0.476 T -52.4 133.9 69.0 0.476 0.0 HOH
 6.806
 C
 O
PRO C:73 B:73 70.0 0.483 T -51.9 140.0 NA NA NA
5n6o 1 P63000 100.0 2e-130 X-RAY
 2017-12-27 PRO A:72 A:73 76.0 0.524 T -49.3 137.4 76.0 0.524 0.0 HOH
 7.272
 O
 O
PRO B:72 B:73 68.0 0.469 T -61.2 142.2 NA NA NA
4yon 2 P63000 99.44 3e-130 X-RAY
 2015-07-01 PRO B:75 B:73 62.0 0.428 T -57.5 141.8 38.0 0.262 0.166 A:Q8TCU6:0.166
 HOH
 3.003
 O
 O
3ryt 2 P63000 99.44 5e-130 X-RAY
 2012-01-18 PRO C:76 C:73 69.0 0.476 T -41.3 128.4 64.0 0.441 0.035 A:P70206:0.034
4gzm 1 P63000 99.43 6e-130 X-RAY
 2012-12-12 PRO A:100 A:73 80.0 0.552 T -63.1 149.4 80.0 0.552 0.0
PRO B:100 B:73 77.0 0.531 T -62.7 149.5 NA NA NA
3sbd 1 P63000 99.43 9e-130 X-RAY
 2012-07-18 PRO A:83 A:73 75.0 0.517 T -53.5 140.0 75.0 0.517 0.0 HOH
 3.810
 CA
 O
PRO B:83 B:73 69.0 0.476 T -55.2 149.8 NA NA NA
3sbe 1 P63000 99.43 9e-130 X-RAY
 2012-07-18 PRO A:83 A:73 77.0 0.531 T -47.0 136.6 77.0 0.531 0.0
6agp 1 P63000 97.79 1e-129 NMR
 2019-03-20 PRO A:73 A:73 85.0 0.586 T -52.4 130.8 85.0 0.586 0.0
1he1 2 P15154 100.0 1e-129 X-RAY
 2001-01-02 PRO C:73 C:73 83.0 0.572 T -51.6 130.8 83.0 0.572 0.0 NI
HOH
 8.505
3.263
 O
O
 NI
O
PRO D:73 D:73 85.0 0.586 T -52.2 132.9 NA NA NA
4gzl 1 P63000 99.43 1e-129 X-RAY
 2012-12-12 PRO A:100 A:73 81.0 0.559 T -47.6 139.5 81.0 0.559 0.0 HOH
 3.815
 CB
 O
PRO B:100 B:73 78.0 0.538 T -52.0 139.7 NA NA NA
7ajk 1 P63000 99.43 3e-129 X-RAY
 2020-11-18 PRO A:76 BBB:73 63.0 0.434 T -51.4 147.7 63.0 0.434 0.0
2wkr 1 O49003,P63000 97.21 1e-128 X-RAY
 2009-08-18 PRO A:225 A:616 47.0 0.324 T -52.4 138.2 47.0 0.324 0.0 HOH
 3.633
 CA
 O
2wkq 1 O49003,P63000 97.21 1e-128 X-RAY
 2009-08-18 PRO A:225 A:616 46.0 0.317 T -57.1 140.9 46.0 0.317 0.0 HOH
 3.634
 CA
 O
2wkp 1 O49003,P63000 97.21 3e-128 X-RAY
 2009-08-18 PRO A:225 A:616 48.0 0.331 T -57.1 136.6 48.0 0.331 0.0 HOH
 3.754
 CG
 O
6tm1 2 P60763 95.51 3e-128 X-RAY
 2020-01-22 PRO B:73 A:73 74.0 0.51 T -44.1 139.7 30.0 0.207 0.303 A:Q96BY6:0.303
2g0n 1 P60763 95.48 1e-127 X-RAY
 2006-05-30 PRO A:74 A:73 82.0 0.566 T -49.3 138.6 82.0 0.566 0.0 HOH
 3.342
 O
 O
PRO B:74 B:73 82.0 0.566 T -46.6 128.6 NA NA NA
2ov2 1 P60763 95.48 1e-127 X-RAY
 2007-03-13 PRO A:74 A:73 84.0 0.579 T -52.6 136.9 84.0 0.579 0.0 HOH
 3.557
 CG
 O
PRO B:74 F:73 76.0 0.524 T -52.8 135.3 NA NA NA
PRO C:74 B:73 69.0 0.476 T -47.9 137.2 NA NA NA
PRO D:74 C:73 67.0 0.462 T -53.5 135.8 NA NA NA
PRO E:74 G:73 70.0 0.483 T -50.8 129.2 NA NA NA
PRO F:74 D:73 69.0 0.476 T -57.9 142.4 NA NA NA
PRO G:74 E:73 84.0 0.579 T -53.7 133.5 NA NA NA
PRO H:74 H:73 81.0 0.559 T -58.4 133.8 NA NA NA
2qme 1 P60763 95.48 1e-127 X-RAY
 2007-08-28 PRO A:74 A:73 80.0 0.552 T -54.4 136.4 80.0 0.552 0.0 HOH
 3.494
 O
 O
2ic5 1 P60763 95.48 1e-127 X-RAY
 2006-10-10 PRO A:74 A:73 82.0 0.566 T -55.0 144.4 82.0 0.566 0.0 HOH
 3.686
 CA
 O
PRO B:74 B:73 83.0 0.572 T -48.1 132.0 NA NA NA
2c2h 1 P60763 95.48 4e-127 X-RAY
 2005-10-13 PRO A:73 A:73 63.0 0.434 T -47.9 138.6 63.0 0.434 0.0 GDP
GDP
HOH
 5.051
7.019
2.981
 CG
CA
O
 O2'
C5'
O
PRO B:73 B:73 63.0 0.434 T -52.5 142.6 NA NA NA
2w2t 1 P15153 94.94 2e-125 X-RAY
 2009-05-05 PRO A:79 A:73 87.0 0.6 T -48.4 132.8 87.0 0.6 0.0 HOH
 3.638
 CG
 O
2w2x 1 P15153 94.94 2e-125 X-RAY
 2009-05-05 PRO A:79 A:73 70.0 0.483 T -56.0 135.2 70.0 0.483 0.0 HOH
 8.198
 O
 O
PRO B:79 B:73 68.0 0.469 T -54.4 134.7 NA NA NA
2w2v 1 P15153 94.92 1e-124 X-RAY
 2009-05-05 PRO A:80 A:73 59.0 0.407 T -51.0 136.3 59.0 0.407 0.0 HOH
 3.177
 CG
 O
PRO B:80 B:73 82.0 0.566 T -47.2 135.9 NA NA NA
PRO C:80 C:73 61.0 0.421 T -47.8 136.1 NA NA NA
PRO D:80 D:73 70.0 0.483 T -43.1 129.3 NA NA NA
5hzh 1 P63000,O49003 92.36 2e-94 X-RAY
 2016-12-21 PRO A:225 A:222 84.0 0.579 T -54.9 148.2 84.0 0.579 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p63000-f1 1 P63000 100.0 2e-143 PRO A:73 A:73 77.0 0.531 T -52.1 136.9
af-p15153-f1 1 P15153 92.19 1e-133 PRO A:73 A:73 79.0 0.545 T -52.4 137.2
af-p60763-f1 1 P60763 95.51 1e-128 PRO A:73 A:73 78.0 0.538 T -52.4 137.5