Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11666336 . A C CCDS5985.1:NM_004462.3:c.133Aag>Cag_NP_004453.3:p.45K>Q Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 LYS A:15 A:45 103.0 0.515 H -55.1 -56.1 103.0 0.515 0.0 HOH
 3.267
 N
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 LYS A:15 A:45 109.0 0.545 H -62.7 -48.4 109.0 0.545 0.0 HOH
 9.431
 O
 O
LYS B:15 B:45 125.0 0.625 H -68.0 -47.1 NA NA NA
LYS C:15 C:45 113.0 0.565 H -69.8 -59.5 NA NA NA
LYS D:15 D:45 57.0 NA H -52.6 -59.2 NA NA NA
LYS E:15 E:45 130.0 0.65 H -58.4 -45.5 NA NA NA
LYS F:15 F:45 126.0 0.63 H -65.3 -52.9 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 LYS A:15 A:45 129.0 0.645 H -69.1 -47.9 129.0 0.645 0.0 HOH
 9.015
 CD
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 LYS A:15 A:45 106.0 0.53 H -58.2 -48.2 106.0 0.53 0.0 HOH
 3.382
 N
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 LYS A:15 A:45 108.0 0.54 H -55.7 -48.3 108.0 0.54 0.0 HOH
 3.291
 NZ
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 LYS A:18 A:45 104.0 0.52 H -64.1 -44.5 104.0 0.52 0.0 HOH
 5.496
 NZ
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 LYS A:18 A:45 115.0 0.575 H -61.1 -47.3 115.0 0.575 0.0 HOH
 2.795
 NZ
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 LYS A:18 A:45 111.0 0.555 H -60.7 -46.9 111.0 0.555 0.0 HOH
 2.649
 NZ
 O
LYS B:18 B:45 109.0 0.545 H -57.5 -52.6 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 LYS A:18 A:45 115.0 0.575 H -60.2 -48.9 74.0 0.37 0.205 B:P37268:0.205
 HOH
 2.908
 O
 O
LYS B:18 B:45 102.0 0.51 H -58.0 -49.5 64.0 0.32 0.19 C:P37268:0.19
 HOH
 2.724
 NZ
 O
LYS C:18 C:45 111.0 0.555 H -60.8 -46.0 66.0 0.33 0.225 A:P37268:0.225
 HOH
 2.721
 NZ
 O
LYS D:18 D:45 121.0 0.605 H -55.9 -47.7 NA NA NA
LYS E:18 E:45 114.0 0.57 H -57.6 -45.2 NA NA NA
LYS F:18 F:45 125.0 0.625 H -55.2 -48.0 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 LYS A:18 A:45 110.0 0.55 H -60.2 -51.3 72.0 0.36 0.19 B:P37268:0.19
 HOH
 2.863
 NZ
 O
LYS B:18 B:45 103.0 0.515 H -59.9 -51.1 64.0 0.32 0.195 C:P37268:0.195
 HOH
 2.695
 NZ
 O
LYS C:18 C:45 103.0 0.515 H -56.9 -49.0 63.0 0.315 0.2 A:P37268:0.2
 HOH
 2.726
 NZ
 O
LYS D:18 D:45 106.0 0.53 H -61.3 -48.6 NA NA NA
LYS E:18 E:45 105.0 0.525 H -58.7 -51.7 NA NA NA
LYS F:18 F:45 95.0 0.475 H -54.7 -58.0 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 LYS A:18 A:45 121.0 0.605 H -52.8 -54.6 78.0 0.39 0.215 B:P37268:0.215
 HOH
 2.996
 N
 O
LYS B:18 B:45 108.0 0.54 H -56.1 -54.0 67.0 0.335 0.205 C:P37268:0.205
 HOH
 2.888
 NZ
 O
LYS C:18 C:45 108.0 0.54 H -62.1 -48.5 64.0 0.32 0.22 A:P37268:0.22
 HOH
 2.908
 NZ
 O
LYS D:18 D:45 115.0 0.575 H -66.2 -45.2 NA NA NA
LYS E:18 E:45 115.0 0.575 H -59.9 -53.7 NA NA NA
LYS F:18 F:45 122.0 0.61 H -60.5 -44.3 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 LYS A:18 A:45 89.0 0.445 H -61.4 -50.6 89.0 0.445 0.0 HOH
 3.090
 O
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 LYS A:18 A:45 112.0 0.56 H -58.8 -45.3 112.0 0.56 0.0 HOH
 3.461
 CD
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 LYS A:18 A:45 100.0 0.5 H -58.2 -55.1 100.0 0.5 0.0 HOH
 3.074
 O
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 LYS A:18 A:45 123.0 0.615 H -57.0 -53.3 123.0 0.615 0.0 HOH
 3.033
 O
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 LYS A:18 A:45 130.0 0.65 H -55.8 -44.3 130.0 0.65 0.0 HOH
 2.830
 O
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 LYS A:15 A:45 105.0 0.525 H -71.7 -41.1 105.0 0.525 0.0 HOH
 2.636
 NZ
 O
LYS B:15 B:45 107.0 0.535 H -67.0 -48.8 NA NA NA
LYS C:15 C:45 107.0 0.535 H -63.1 -50.3 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LYS A:35 A:45 106.0 0.53 H -65.7 -46.8 63.0 0.315 0.215 C:P37268:0.215
 HOH
 2.915
 NZ
 O
LYS B:35 B:45 108.0 0.54 H -78.2 -38.9 68.0 0.34 0.2 A:P37268:0.2
 HOH
 3.079
 NZ
 O
LYS C:35 C:45 115.0 0.575 H -60.7 -51.1 79.0 0.395 0.18 B:P37268:0.18
 HOH
 3.800
 CA
 O
LYS D:35 D:45 114.0 0.57 H -66.3 -48.1 74.0 0.37 0.2 F:P37268:0.2
 HOH
 3.464
 NZ
 O
LYS E:35 E:45 101.0 0.505 H -58.0 -41.3 56.0 0.28 0.225 D:P37268:0.225
 HOH
 3.339
 CD
 O
LYS F:35 F:45 123.0 0.615 H -81.0 -28.4 79.0 0.395 0.22 E:P37268:0.22
 HOH
 4.873
 NZ
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LYS A:35 A:45 124.0 0.62 H -81.7 -34.1 80.0 0.4 0.22 C:P37268:0.22
 HOH
 4.732
 NZ
 O
LYS B:35 B:45 116.0 0.58 H -69.0 -44.3 75.0 0.375 0.205 A:P37268:0.205
 HOH
 3.679
 NZ
 O
LYS C:35 C:45 126.0 0.63 H -72.3 -45.4 82.0 0.41 0.22 B:P37268:0.22
 HOH
 3.139
 NZ
 O
LYS D:35 D:45 108.0 0.54 H -65.7 -40.3 64.0 0.32 0.22 F:P37268:0.22
 HOH
 3.718
 CD
 O
LYS E:35 E:45 101.0 0.505 H -64.9 -44.9 59.0 0.295 0.21 D:P37268:0.21
 HOH
 5.408
 CE
 O
LYS F:35 F:45 120.0 0.6 H -81.2 -32.4 75.0 0.375 0.225 E:P37268:0.225
 HOH
 3.495
 CD
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LYS A:35 A:45 106.0 0.53 H -66.9 -47.8 68.0 0.34 0.19 C:P37268:0.19
 HOH
 6.531
 NZ
 O
LYS B:35 B:45 105.0 0.525 H -67.7 -45.5 61.0 0.305 0.22 A:P37268:0.22
 HOH
 2.836
 NZ
 O
LYS C:35 C:45 105.0 0.525 H -69.7 -47.7 65.0 0.325 0.2 B:P37268:0.2
 HOH
 3.829
 N
 O
LYS D:35 D:45 105.0 0.525 H -68.4 -44.8 63.0 0.315 0.21 F:P37268:0.21
 HOH
 4.146
 NZ
 O
LYS E:35 E:45 108.0 0.54 H -69.2 -45.7 64.0 0.32 0.22 D:P37268:0.22
LYS F:35 F:45 105.0 0.525 H -70.0 -38.7 61.0 0.305 0.22 E:P37268:0.22
 HOH
 3.672
 N
 O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LYS A:35 A:45 111.0 0.555 H -70.7 -45.4 71.0 0.355 0.2 C:P37268:0.2
 HOH
 4.856
 O
 O
LYS B:35 B:45 119.0 0.595 H -64.0 -44.4 73.0 0.365 0.23 A:P37268:0.23
 HOH
 2.875
 NZ
 O
LYS C:35 C:45 106.0 0.53 H -68.7 -41.5 65.0 0.325 0.205 B:P37268:0.205
 HOH
 3.640
 N
 O
LYS D:35 D:45 107.0 0.535 H -69.0 -42.3 65.0 0.325 0.21 F:P37268:0.21
 HOH
 3.356
 O
 O
LYS E:35 E:45 105.0 0.525 H -70.0 -42.7 66.0 0.33 0.195 D:P37268:0.195
LYS F:35 F:45 110.0 0.55 H -72.4 -37.8 73.0 0.365 0.185 E:P37268:0.185
 HOH
 6.226
 NZ
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LYS A:35 A:45 110.0 0.55 H -71.5 -44.5 68.0 0.34 0.21 C:P37268:0.21
 HOH
 3.111
 NZ
 O
LYS B:35 B:45 111.0 0.555 H -65.7 -46.4 72.0 0.36 0.195 A:P37268:0.195
 HOH
 2.668
 NZ
 O
LYS C:35 C:45 121.0 0.605 H -66.9 -46.4 81.0 0.405 0.2 B:P37268:0.2
 HOH
 3.111
 NZ
 O
LYS D:35 D:45 115.0 0.575 H -66.6 -44.0 75.0 0.375 0.2 F:P37268:0.2
 HOH
 3.080
 O
 O
LYS E:35 E:45 112.0 0.56 H -65.7 -47.6 66.0 0.33 0.23 D:P37268:0.23
 HOH
 3.238
 CE
 O
LYS F:35 F:45 113.0 0.565 H -70.7 -46.9 75.0 0.375 0.19 E:P37268:0.19
 HOH
 2.625
 NZ
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LYS A:35 A:45 110.0 0.55 H -67.3 -47.1 71.0 0.355 0.195 C:P37268:0.195
 HOH
 2.923
 O
 O
LYS B:35 B:45 108.0 0.54 H -66.5 -47.6 66.0 0.33 0.21 A:P37268:0.21
 HOH
 2.648
 NZ
 O
LYS C:35 C:45 116.0 0.58 H -66.4 -47.4 75.0 0.375 0.205 B:P37268:0.205
 HOH
 2.484
 NZ
 O
LYS D:35 D:45 109.0 0.545 H -63.0 -47.4 69.0 0.345 0.2 F:P37268:0.2
 HOH
 2.813
 NZ
 O
LYS E:35 E:45 114.0 0.57 H -65.5 -40.3 72.0 0.36 0.21 D:P37268:0.21
 HOH
 3.516
 CD
 O
LYS F:35 F:45 115.0 0.575 H -73.3 -37.3 73.0 0.365 0.21 E:P37268:0.21
 HOH
 4.705
 CD
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LYS A:35 A:45 110.0 0.55 H -72.5 -44.6 68.0 0.34 0.21 C:P37268:0.21
 HOH
 2.996
 O
 O
LYS B:35 B:45 112.0 0.56 H -64.2 -46.4 71.0 0.355 0.205 A:P37268:0.205
 HOH
 2.902
 O
 O
LYS C:35 C:45 97.0 0.485 H -67.6 -45.9 60.0 0.3 0.185 B:P37268:0.185
 HOH
 3.420
 NZ
 O
LYS D:35 D:45 113.0 0.565 H -67.1 -45.9 72.0 0.36 0.205 F:P37268:0.205
 HOH
 3.058
 NZ
 O
LYS E:35 E:45 105.0 0.525 H -66.7 -41.8 68.0 0.34 0.185 D:P37268:0.185
 HOH
 3.774
 N
 O
LYS F:35 F:45 123.0 0.615 H -68.1 -42.9 81.0 0.405 0.21 E:P37268:0.21
 HOH
 3.084
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LYS A:35 A:45 111.0 0.555 H -66.5 -48.2 72.0 0.36 0.195 C:P37268:0.195
 HOH
 2.600
 NZ
 O
LYS B:35 B:45 104.0 0.52 H -67.8 -45.6 65.0 0.325 0.195 A:P37268:0.195
 HOH
 2.711
 NZ
 O
LYS C:35 C:45 99.0 0.495 H -67.1 -48.1 64.0 0.32 0.175 B:P37268:0.175
 HOH
 2.644
 NZ
 O
LYS D:35 D:45 109.0 0.545 H -65.0 -45.4 69.0 0.345 0.2 F:P37268:0.2
 HOH
 3.243
 NZ
 O
LYS E:35 E:45 107.0 0.535 H -69.4 -44.3 65.0 0.325 0.21 D:P37268:0.21
 HOH
 3.404
 CD
 O
LYS F:35 F:45 115.0 0.575 H -67.2 -43.4 72.0 0.36 0.215 E:P37268:0.215
 HOH
 2.907
 O
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 LYS A:35 A:45 135.0 0.675 H -72.9 -39.3 88.0 0.44 0.235 C:P37268:0.235
 HOH
 6.416
 CE
 O
LYS B:35 B:45 103.0 0.515 H -69.3 -46.9 66.0 0.33 0.185 A:P37268:0.185
 HOH
 3.361
 NZ
 O
LYS C:35 C:45 120.0 0.6 H -66.6 -44.2 70.0 0.35 0.25 B:P37268:0.25
 HOH
 8.640
 CE
 O
LYS D:35 D:45 106.0 0.53 H -77.6 -45.9 70.0 0.35 0.18 F:P37268:0.18
LYS E:35 E:45 106.0 0.53 H -63.7 -42.2 64.0 0.32 0.21 D:P37268:0.21
LYS F:35 F:45 118.0 0.59 H -77.1 -32.5 78.0 0.39 0.2 E:P37268:0.2
 HOH
 9.352
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 LYS A:45 A:45 118.0 0.59 H -61.6 -47.0