Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11666350 . G A CCDS5985.1:NM_004462.3:c.147caG>caA_NP_004453.3:p.49Q>Q Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLN A:19 A:49 67.0 0.372 H -63.2 -63.8 67.0 0.372 0.0 D99
HOH
 9.337
8.387
 O
OE1
 O4
O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 GLN A:19 A:49 106.0 0.589 H -58.9 -35.2 106.0 0.589 0.0 HOH
 3.829
 O
 O
GLN B:19 B:49 92.0 0.511 H -66.1 -34.6 NA NA NA
GLN C:19 C:49 109.0 0.606 H -95.8 -11.6 NA NA NA
GLN D:19 D:49 109.0 0.606 H -77.2 -19.0 NA NA NA
GLN E:19 E:49 80.0 NA H -64.3 -41.0 NA NA NA
GLN F:19 F:49 103.0 0.572 H -108.1 -22.9 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLN A:19 A:49 117.0 0.65 H -65.4 -41.9 117.0 0.65 0.0 D9A
 8.471
 O
 O39
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLN A:19 A:49 110.0 0.611 H -84.5 -28.8 110.0 0.611 0.0 D61
HOH
 9.597
2.430
 O
NE2
 O40
O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 GLN A:19 A:49 114.0 0.633 H -69.3 -38.9 114.0 0.633 0.0 HOH
 2.801
 NE2
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLN A:22 A:49 78.0 0.433 H -75.8 -30.9 78.0 0.433 0.0 HOH
 2.705
 OE1
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLN A:22 A:49 91.0 0.506 H -62.3 -39.7 91.0 0.506 0.0 HOH
 2.743
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLN A:22 A:49 68.0 0.378 H -67.0 -40.2 68.0 0.378 0.0 HOH
 3.671
 CG
 O
GLN B:22 B:49 98.0 0.544 H -64.4 -37.7 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLN A:22 A:49 86.0 0.478 H -65.7 -42.2 80.0 0.444 0.034 B:P37268:0.033
 HOH
 3.580
 CG
 O
GLN B:22 B:49 106.0 0.589 H -74.6 -35.3 82.0 0.456 0.133 C:P37268:0.133
 HOH
 4.303
 O
 O
GLN C:22 C:49 103.0 0.572 H -67.3 -37.3 98.0 0.544 0.028 A:P37268:0.028
 HOH
 2.561
 NE2
 O
GLN D:22 D:49 88.0 0.489 H -87.8 -20.7 NA NA NA
GLN E:22 E:49 83.0 0.461 H -70.6 -35.1 NA NA NA
GLN F:22 F:49 96.0 0.533 H -62.8 -46.2 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLN A:22 A:49 108.0 0.6 H -66.0 -33.2 99.0 0.55 0.05 B:P37268:0.05
 ZGA
HOH
 6.624
2.722
 O
OE1
 OAP
O
GLN B:22 B:49 130.0 0.722 H -69.3 -30.1 98.0 0.544 0.178 C:P37268:0.178
 ZGA
HOH
 6.526
2.676
 O
OE1
 OAM
O
GLN C:22 C:49 132.0 0.733 H -68.4 -28.8 103.0 0.572 0.161 A:P37268:0.161
 ZGA
HOH
 6.567
2.792
 O
O
 OAM
O
GLN D:22 D:49 117.0 0.65 H -72.6 -32.0 NA NA NA
GLN E:22 E:49 135.0 0.75 H -75.0 -20.9 NA NA NA
GLN F:22 F:49 126.0 0.7 H -82.9 -25.7 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLN A:22 A:49 97.0 0.539 H -66.5 -40.2 88.0 0.489 0.05 B:P37268:0.05
 FPS
HOH
 6.246
5.703
 O
OE1
 O3B
O
GLN B:22 B:49 110.0 0.611 H -72.0 -21.5 89.0 0.494 0.117 C:P37268:0.117
 FPS
HOH
 7.611
5.807
 O
NE2
 O1B
O
GLN C:22 C:49 108.0 0.6 H -73.0 -37.3 102.0 0.567 0.033 A:P37268:0.033
 FPS
HOH
 6.417
5.029
 O
NE2
 O3B
O
GLN D:22 D:49 83.0 0.461 H -67.3 -27.2 NA NA NA
GLN E:22 E:49 126.0 0.7 H -69.8 -34.0 NA NA NA
GLN F:22 F:49 108.0 0.6 H -63.2 -44.6 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLN A:22 A:49 104.0 0.578 H -75.6 -40.0 104.0 0.578 0.0 FPS
HOH
 7.346
3.559
 O
CG
 O3B
O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLN A:22 A:49 87.0 0.483 H -82.5 -30.5 87.0 0.483 0.0 PS7
HOH
 8.170
4.831
 O
N
 OAK
O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLN A:22 A:49 119.0 0.661 H -60.2 -41.3 119.0 0.661 0.0 PS7
HOH
 7.522
3.355
 O
CG
 OAK
O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLN A:22 A:49 95.0 0.528 H -77.2 -37.6 95.0 0.528 0.0 PS7
HOH
 8.860
4.080
 C
CG
 CAE
O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLN A:22 A:49 114.0 0.633 H -61.5 -44.5 114.0 0.633 0.0 PS7
HOH
 8.025
3.170
 O
CG
 OAI
O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 GLN A:19 A:49 108.0 0.6 H -71.7 -35.3 108.0 0.6 0.0 IN0
HOH
 7.826
5.409
 O
OE1
 O63
O
GLN B:19 B:49 91.0 0.506 H -77.5 -29.9 NA NA NA
GLN C:19 C:49 94.0 0.522 H -79.3 -14.0 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:39 A:49 89.0 0.494 H -83.0 -38.3 78.0 0.433 0.061 C:P37268:0.061
 FPS
HOH
 7.841
3.609
 O
NE2
 O1B
O
GLN B:39 B:49 106.0 0.589 H -89.2 -32.9 96.0 0.533 0.056 A:P37268:0.056
 FPS
HOH
 8.418
3.548
 O
CG
 O1B
O
GLN C:39 C:49 109.0 0.606 H -85.1 -26.4 91.0 0.506 0.1 B:P37268:0.1
 FPS
HOH
 7.900
7.156
 O
C
 O1B
O
GLN D:39 D:49 99.0 0.55 H -69.7 -12.6 89.0 0.494 0.056 F:P37268:0.056
 FPS
FPS
HOH
 8.436
9.257
3.019
 O
O
NE2
 O1B
O2B
O
GLN E:39 E:49 96.0 0.533 T -107.5 0.0 81.0 0.45 0.083 D:P37268:0.083
 FPS
HOH
 9.034
4.714
 C
NE2
 O2A
O
GLN F:39 F:49 89.0 0.494 H -91.1 -52.7 88.0 0.489 0.005 E:P37268:0.006
 FPS
HOH
 8.237
3.391
 O
NE2
 O1B
O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:39 A:49 85.0 0.472 H -86.1 -62.5 82.0 0.456 0.016 C:P37268:0.017
 HOH
 5.305
 O
 O
GLN B:39 B:49 97.0 0.539 H -83.6 -42.3 96.0 0.533 0.006 A:P37268:0.006
 HOH
 3.082
 CG
 O
GLN C:39 C:49 92.0 0.511 H -82.6 -42.7 90.0 0.5 0.011 B:P37268:0.011
 HOH
 3.836
 O
 O
GLN D:39 D:49 99.0 0.55 H -82.3 -24.6 99.0 0.55 0.0 HOH
 4.198
 NE2
 O
GLN E:39 E:49 91.0 0.506 H -88.1 -37.6 83.0 0.461 0.045 D:P37268:0.044
 HOH
 5.891
 NE2
 O
GLN F:39 F:49 86.0 0.478 H -69.2 -53.0 86.0 0.478 0.0 HOH
 4.053
 CD
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:39 A:49 105.0 0.583 H -74.8 -36.2 95.0 0.528 0.055 C:P37268:0.056
 BH8
HOH
 9.214
3.695
 O
OE1
 OAB
O
GLN B:39 B:49 105.0 0.583 H -80.1 -29.9 95.0 0.528 0.055 A:P37268:0.056
 BH8
HOH
 7.414
5.303
 O
N
 OAC
O
GLN C:39 C:49 111.0 0.617 H -81.6 -33.2 86.0 0.478 0.139 B:P37268:0.139
 BH8
HOH
 8.153
7.968
 O
CG
 OAF
O
GLN D:39 D:49 111.0 0.617 H -77.6 -28.6 98.0 0.544 0.073 F:P37268:0.072
 BH8
HOH
 7.148
7.908
 O
NE2
 OAC
O
GLN E:39 E:49 105.0 0.583 H -88.8 -41.2 92.0 0.511 0.072 D:P37268:0.072
 BH8
 7.164
 O
 OAC
GLN F:39 F:49 102.0 0.567 H -65.5 -48.2 101.0 0.561 0.006 E:P37268:0.006
 BH8
HOH
 7.442
8.524
 O
NE2
 OAC
O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:39 A:49 102.0 0.567 H -74.5 -40.1 97.0 0.539 0.028 C:P37268:0.028
 8PH
HOH
 6.004
3.338
 O
OE1
 OAH
O
GLN B:39 B:49 89.0 0.494 H -66.4 -44.9 88.0 0.489 0.005 A:P37268:0.006
 HOH
 6.513
 O
 O
GLN C:39 C:49 107.0 0.594 H -79.9 -40.5 96.0 0.533 0.061 B:P37268:0.061
 HOH
 8.290
 O
 O
GLN D:39 D:49 107.0 0.594 H -65.1 -41.3 102.0 0.567 0.027 F:P37268:0.028
 HOH
 3.151
 CG
 O
GLN E:39 E:49 110.0 0.611 H -69.4 -46.3 100.0 0.556 0.055 D:P37268:0.056
 8PH
HOH
 7.758
7.456
 O
O
 OAH
O
GLN F:39 F:49 99.0 0.55 H -82.6 -51.1 98.0 0.544 0.006 E:P37268:0.006
 8PH
8PH
HOH
 9.538
6.265
5.139
 O
O
O
 OAG
OAE
O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:39 A:49 90.0 0.5 H -69.2 -41.9 83.0 0.461 0.039 C:P37268:0.039
 BH5
HOH
 6.718
3.403
 O
CG
 OAD
O
GLN B:39 B:49 105.0 0.583 H -75.6 -43.6 105.0 0.583 0.0 BH5
HOH
 6.620
3.441
 O
O
 OAD
O
GLN C:39 C:49 107.0 0.594 H -73.5 -46.0 98.0 0.544 0.05 B:P37268:0.05
 BH5
HOH
 7.130
4.082
 O
CG
 OAD
O
GLN D:39 D:49 111.0 0.617 H -71.7 -49.8 106.0 0.589 0.028 F:P37268:0.028
 BH5
HOH
 6.690
3.239
 O
CG
 OAB
O
GLN E:39 E:49 78.0 0.433 H -98.0 -28.5 66.0 0.367 0.066 D:P37268:0.067
 BH5
HOH
 5.724
7.100
 O
OE1
 OAD
O
GLN F:39 F:49 99.0 0.55 H -68.4 -51.2 98.0 0.544 0.006 E:P37268:0.006
 BH5
HOH
 6.819
3.374
 O
O
 OAD
O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:39 A:49 93.0 0.517 H -75.8 -30.1 85.0 0.472 0.045 C:P37268:0.044
 HOH
 3.301
 CG
 O
GLN B:39 B:49 103.0 0.572 H -70.7 -46.2 101.0 0.561 0.011 A:P37268:0.011
 HOH
 3.777
 N
 O
GLN C:39 C:49 95.0 0.528 H -73.0 -33.6 90.0 0.5 0.028 B:P37268:0.028
 HOH
 3.120
 OE1
 O
GLN D:39 D:49 121.0 0.672 H -76.7 -23.7 105.0 0.583 0.089 F:P37268:0.089
 HOH
 3.017
 NE2
 O
GLN E:39 E:49 85.0 0.472 H -76.3 -44.7 79.0 0.439 0.033 D:P37268:0.033
 HOH
 6.987
 NE2
 O
GLN F:39 F:49 91.0 0.506 H -57.2 -50.1 86.0 0.478 0.028 E:P37268:0.028
 HOH
 3.411
 O
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:39 A:49 92.0 0.511 H -74.4 -41.3 85.0 0.472 0.039 C:P37268:0.039
 BH3
HOH
 6.575
3.291
 O
CG
 OAF
O
GLN B:39 B:49 113.0 0.628 H -75.5 -38.1 110.0 0.611 0.017 A:P37268:0.017
 HOH
 3.004
 O
 O
GLN C:39 C:49 104.0 0.578 H -79.8 -41.7 89.0 0.494 0.084 B:P37268:0.083
 HOH
 4.045
 NE2
 O
GLN D:39 D:49 114.0 0.633 H -73.2 -45.8 108.0 0.6 0.033 F:P37268:0.033
 HOH
 3.434
 NE2
 O
GLN E:39 E:49 89.0 0.494 H -83.4 -32.4 70.0 0.389 0.105 D:P37268:0.106
 HOH
 3.556
 NE2
 O
GLN F:39 F:49 96.0 0.533 H -67.0 -45.4 90.0 0.5 0.033 E:P37268:0.033
 HOH
 3.990
 CG
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:39 A:49 97.0 0.539 H -74.9 -32.5 90.0 0.5 0.039 C:P37268:0.039
 ER4
HOH
 9.886
3.152
 C
O
 CAP
O
GLN B:39 B:49 113.0 0.628 H -71.8 -38.4 110.0 0.611 0.017 A:P37268:0.017
 HOH
 2.843
 OE1
 O
GLN C:39 C:49 120.0 0.667 H -78.6 -34.2 96.0 0.533 0.134 B:P37268:0.133
 HOH
 3.932
 O
 O
GLN D:39 D:49 125.0 0.694 H -75.2 -24.0 106.0 0.589 0.105 F:P37268:0.106
 HOH
 3.565
 NE2
 O
GLN E:39 E:49 87.0 0.483 H -75.6 -39.0 80.0 0.444 0.039 D:P37268:0.039
 HOH
 5.166
 N
 O
GLN F:39 F:49 90.0 0.5 H -71.3 -43.8 89.0 0.494 0.006 E:P37268:0.006
 HOH
 3.321
 O
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 GLN A:39 A:49 87.0 0.483 H -73.9 -52.9 84.0 0.467 0.016 C:P37268:0.017
 HOH
 3.910
 OE1
 O
GLN B:39 B:49 114.0 0.633 H -84.2 -34.7 111.0 0.617 0.016 A:P37268:0.017
 HOH
 3.573
 NE2
 O
GLN C:39 C:49 94.0 0.522 H -100.3 -3.8 92.0 0.511 0.011 B:P37268:0.011
 HOH
 8.129
 CB
 O
GLN D:39 D:49 108.0 0.6 H -69.7 -20.4 100.0 0.556 0.044 F:P37268:0.044
 HOH
 7.852
 O
 O
GLN E:39 E:49 93.0 0.517 H -92.7 -26.1 76.0 0.422 0.095 D:P37268:0.094
 RWZ
 9.753
 C
 CAM
GLN F:39 F:49 96.0 0.533 H -87.1 -51.8 94.0 0.522 0.011 E:P37268:0.011
 HOH
 6.481
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 GLN A:49 A:49 106.0 0.589 H -76.7 -37.0