Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11666391 . G A CCDS5985.1:NM_004462.3:c.188gGg>gAg_NP_004453.3:p.63G>E Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLY A:33 A:63 60.0 0.8 T 59.7 -135.5 60.0 0.8 0.0 HOH
 2.591
 O
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 GLY A:33 A:63 48.0 0.64 T 67.9 -148.4 48.0 0.64 0.0 HOH
 7.504
 C
 O
GLY B:33 B:63 54.0 0.72 T 53.5 -151.6 NA NA NA
GLY C:33 C:63 54.0 0.72 T 55.8 -124.7 NA NA NA
GLY D:33 D:63 49.0 0.653 T 62.6 -129.6 NA NA NA
GLY E:33 E:63 56.0 0.747 T 57.4 -109.0 NA NA NA
GLY F:33 F:63 55.0 0.733 T 62.3 -132.3 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLY A:33 A:63 57.0 0.76 H 57.9 -137.8 57.0 0.76 0.0 HOH
 2.611
 O
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLY A:33 A:63 59.0 0.787 T 53.9 -134.8 59.0 0.787 0.0 HOH
 2.543
 O
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 GLY A:33 A:63 58.0 0.773 T 54.1 -140.1 58.0 0.773 0.0 HOH
 2.765
 O
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLY A:36 A:63 54.0 0.72 T 53.6 -139.5 54.0 0.72 0.0 HOH
 2.851
 O
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLY A:36 A:63 39.0 0.52 T 45.6 -128.7 39.0 0.52 0.0 HOH
 2.710
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLY A:36 A:63 46.0 0.613 T 53.6 -137.2 46.0 0.613 0.0 HOH
 2.560
 O
 O
GLY B:36 B:63 60.0 0.8 T 52.6 -133.8 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLY A:36 A:63 56.0 0.747 T 45.9 -126.9 56.0 0.747 0.0 HOH
 2.634
 O
 O
GLY B:36 B:63 56.0 0.747 T 46.2 -134.7 56.0 0.747 0.0 HOH
 2.801
 O
 O
GLY C:36 C:63 57.0 0.76 T 53.4 -138.1 57.0 0.76 0.0 HOH
 2.581
 O
 O
GLY D:36 D:63 59.0 0.787 T 40.8 -126.6 NA NA NA
GLY E:36 E:63 59.0 0.787 T 38.3 -123.5 NA NA NA
GLY F:36 F:63 57.0 0.76 T 49.3 -125.2 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLY A:36 A:63 58.0 0.773 T 49.0 -130.8 58.0 0.773 0.0 HOH
 2.698
 O
 O
GLY B:36 B:63 57.0 0.76 T 44.4 -132.0 57.0 0.76 0.0 HOH
 2.647
 O
 O
GLY C:36 C:63 54.0 0.72 H 53.6 -137.4 53.0 0.707 0.013 A:P37268:0.013
 HOH
 2.644
 O
 O
GLY D:36 D:63 57.0 0.76 T 54.5 -133.4 NA NA NA
GLY E:36 E:63 56.0 0.747 T 52.4 -136.2 NA NA NA
GLY F:36 F:63 55.0 0.733 T 51.0 -134.6 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLY A:36 A:63 57.0 0.76 T 51.9 -133.0 57.0 0.76 0.0 HOH
 2.663
 O
 O
GLY B:36 B:63 57.0 0.76 T 43.7 -132.9 57.0 0.76 0.0 HOH
 3.190
 N
 O
GLY C:36 C:63 57.0 0.76 T 49.2 -131.6 57.0 0.76 0.0 HOH
 2.705
 O
 O
GLY D:36 D:63 55.0 0.733 T 43.2 -136.4 NA NA NA
GLY E:36 E:63 56.0 0.747 T 50.4 -133.5 NA NA NA
GLY F:36 F:63 56.0 0.747 T 45.0 -130.8 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLY A:36 A:63 56.0 0.747 T 49.8 -131.7 56.0 0.747 0.0 HOH
 2.535
 O
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLY A:36 A:63 56.0 0.747 T 55.8 -135.6 56.0 0.747 0.0 HOH
 2.668
 O
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLY A:36 A:63 58.0 0.773 T 59.0 -133.0 58.0 0.773 0.0 HOH
 2.598
 O
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLY A:36 A:63 54.0 0.72 T 57.0 -139.9 54.0 0.72 0.0 HOH
 2.693
 O
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLY A:36 A:63 60.0 0.8 T 51.5 -135.6 60.0 0.8 0.0 HOH
 2.707
 O
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 GLY A:33 A:63 58.0 0.773 T 38.7 -131.6 58.0 0.773 0.0 HOH
 2.634
 O
 O
GLY B:33 B:63 57.0 0.76 T 39.0 -129.1 NA NA NA
GLY C:33 C:63 56.0 0.747 T 34.9 -132.7 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLY A:53 A:63 53.0 0.707 H 38.7 -130.7 53.0 0.707 0.0 HOH
 2.736
 N
 O
GLY B:53 B:63 56.0 0.747 T 43.7 -116.8 28.0 0.373 0.374 D:P37268:0.373
 HOH
 3.017
 N
 O
GLY C:53 C:63 60.0 0.8 H 35.1 -126.5 60.0 0.8 0.0 HOH
 3.549
 CA
 O
GLY D:53 D:63 55.0 0.733 T 23.3 -127.4 21.0 0.28 0.453 B:P37268:0.453
 HOH
 4.580
 N
 O
GLY E:53 E:63 56.0 0.747 H 25.6 -96.5 53.0 0.707 0.04 A:P37268:0.04
 HOH
 3.149
 N
 O
GLY F:53 F:63 52.0 0.693 T 31.5 -142.2 52.0 0.693 0.0 HOH
 4.031
 CA
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLY A:53 A:63 55.0 0.733 T 38.7 -127.8 55.0 0.733 0.0 HOH
 2.602
 N
 O
GLY B:53 B:63 59.0 0.787 T 40.6 -126.5 26.0 0.347 0.44 D:P37268:0.44
 HOH
 2.841
 N
 O
GLY C:53 C:63 57.0 0.76 H 34.5 -127.5 57.0 0.76 0.0 HOH
 3.085
 N
 O
GLY D:53 D:63 57.0 0.76 T 39.8 -130.8 25.0 0.333 0.427 B:P37268:0.427
 HOH
 4.126
 CA
 O
GLY E:53 E:63 54.0 0.72 H 24.4 -118.8 54.0 0.72 0.0 HOH
 3.596
 N
 O
GLY F:53 F:63 60.0 0.8 T 41.6 -127.2 60.0 0.8 0.0 HOH
 3.270
 CA
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLY A:53 A:63 54.0 0.72 T 36.3 -127.6 50.0 0.667 0.053 E:P37268:0.053
 HOH
 2.541
 O
 O
GLY B:53 B:63 56.0 0.747 T 29.2 -125.3 25.0 0.333 0.414 D:P37268:0.413
 HOH
 2.657
 O
 O
GLY C:53 C:63 54.0 0.72 T 27.0 -131.4 54.0 0.72 0.0 HOH
 2.785
 O
 O
GLY D:53 D:63 56.0 0.747 T 26.2 -122.2 24.0 0.32 0.427 B:P37268:0.427
 HOH
 2.899
 O
 O
GLY E:53 E:63 57.0 0.76 H 28.9 -121.1 48.0 0.64 0.12 A:P37268:0.12
 HOH
 2.532
 O
 O
GLY F:53 F:63 51.0 0.68 T 27.5 -132.0 51.0 0.68 0.0 HOH
 7.040
 N
 O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLY A:53 A:63 58.0 0.773 T 29.3 -127.2 58.0 0.773 0.0 HOH
 2.593
 O
 O
GLY B:53 B:63 56.0 0.747 T 38.0 -126.2 30.0 0.4 0.347 D:P37268:0.347
 HOH
 2.817
 O
 O
GLY C:53 C:63 55.0 0.733 T 27.5 -127.4 55.0 0.733 0.0 HOH
 2.703
 O
 O
GLY D:53 D:63 54.0 0.72 T 33.8 -130.4 22.0 0.293 0.427 B:P37268:0.427
 HOH
 2.712
 O
 O
GLY E:53 E:63 53.0 0.707 T 34.6 -119.8 53.0 0.707 0.0 HOH
 4.062
 N
 O
GLY F:53 F:63 56.0 0.747 T 33.2 -129.2 56.0 0.747 0.0 HOH
 3.102
 N
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLY A:53 A:63 57.0 0.76 T 37.5 -131.0 57.0 0.76 0.0 HOH
 2.811
 O
 O
GLY B:53 B:63 56.0 0.747 H 29.5 -120.9 27.0 0.36 0.387 D:P37268:0.373
 HOH
 2.744
 O
 O
GLY C:53 C:63 56.0 0.747 H 35.1 -129.3 56.0 0.747 0.0 HOH
 2.697
 O
 O
GLY D:53 D:63 55.0 0.733 T 37.2 -129.8 19.0 0.253 0.48 B:P37268:0.48
 HOH
 2.889
 N
 O
GLY E:53 E:63 56.0 0.747 T 41.1 -123.2 56.0 0.747 0.0 HOH
 3.554
 N
 O
GLY F:53 F:63 56.0 0.747 T 33.8 -127.7 56.0 0.747 0.0 HOH
 2.763
 O
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLY A:53 A:63 56.0 0.747 T 37.3 -125.7 44.0 0.587 0.16 C:P37268:0.16
 HOH
 2.703
 O
 O
GLY B:53 B:63 55.0 0.733 H 31.3 -118.0 28.0 0.373 0.36 D:P37268:0.36
 HOH
 2.493
 O
 O
GLY C:53 C:63 57.0 0.76 H 25.2 -124.2 57.0 0.76 0.0 HOH
 2.656
 O
 O
GLY D:53 D:63 56.0 0.747 T 24.8 -122.2 23.0 0.307 0.44 F:P37268:0.013
B:P37268:0.44
 HOH
 2.669
 O
 O
GLY E:53 E:63 55.0 0.733 H 32.5 -130.6 46.0 0.613 0.12 A:P37268:0.013
D:P37268:0.107
 HOH
 2.875
 N
 O
GLY F:53 F:63 55.0 0.733 T 29.8 -127.2 50.0 0.667 0.066 E:P37268:0.067
 HOH
 4.017
 CA
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLY A:53 A:63 55.0 0.733 T 36.1 -132.3 55.0 0.733 0.0 HOH
 2.720
 O
 O
GLY B:53 B:63 55.0 0.733 H 30.1 -124.2 27.0 0.36 0.373 D:P37268:0.373
 HOH
 2.704
 O
 O
GLY C:53 C:63 55.0 0.733 T 33.9 -128.2 55.0 0.733 0.0 HOH
 2.683
 O
 O
GLY D:53 D:63 55.0 0.733 H 30.5 -125.1 24.0 0.32 0.413 B:P37268:0.413
 HOH
 2.673
 O
 O
GLY E:53 E:63 55.0 0.733 T 35.7 -128.0 54.0 0.72 0.013 A:P37268:0.013
 HOH
 3.110
 N
 O
GLY F:53 F:63 56.0 0.747 T 40.7 -124.2 53.0 0.707 0.04 E:P37268:0.04
 HOH
 2.492
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLY A:53 A:63 56.0 0.747 T 35.8 -130.0 38.0 0.507 0.24 C:P37268:0.24
 HOH
 2.735
 O
 O
GLY B:53 B:63 57.0 0.76 H 30.3 -123.7 29.0 0.387 0.373 D:P37268:0.373
 HOH
 2.537
 O
 O
GLY C:53 C:63 55.0 0.733 T 37.6 -132.4 54.0 0.72 0.013 B:P37268:0.013
 HOH
 2.696
 N
 O
GLY D:53 D:63 56.0 0.747 T 30.4 -124.7 23.0 0.307 0.44 B:P37268:0.427
 HOH
 2.777
 O
 O
GLY E:53 E:63 57.0 0.76 H 38.7 -125.5 37.0 0.493 0.267 D:P37268:0.267
 HOH
 2.729
 O
 O
GLY F:53 F:63 55.0 0.733 T 29.1 -128.1 44.0 0.587 0.146 E:P37268:0.147
 HOH
 2.895
 O
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 GLY A:53 A:63 52.0 0.693 T 42.7 -142.6 35.0 0.467 0.226 C:P37268:0.227
 HOH
 2.706
 O
 O
GLY B:53 B:63 53.0 0.707 T 53.6 -135.9 24.0 0.32 0.387 D:P37268:0.387
 HOH
 4.597
 N
 O
GLY C:53 C:63 57.0 0.76 T 39.3 -130.6 57.0 0.76 0.0 HOH
 4.281
 N
 O
GLY D:53 D:63 54.0 0.72 T 51.9 -138.6 26.0 0.347 0.373 B:P37268:0.373
 HOH
 3.799
 N
 O
GLY E:53 E:63 53.0 0.707 T 51.4 -130.3 34.0 0.453 0.254 D:P37268:0.253
GLY F:53 F:63 53.0 0.707 T 36.3 -125.3 49.0 0.653 0.054 E:P37268:0.053
 HOH
 3.881
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 GLY A:63 A:63 51.0 0.68 H 48.8 -139.6