Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11667238 . C A CCDS5985.1:NM_004462.3:c.260aCc>aAc_NP_004453.3:p.87T>N Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 THR A:57 A:87 89.0 0.636 T -93.0 -2.9 89.0 0.636 0.0 HOH
 3.280
 O
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 THR A:57 A:87 94.0 0.671 T -80.0 -19.9 94.0 0.671 0.0 HOH
 5.093
 N
 O
THR B:57 B:87 93.0 0.664 T -94.0 0.7 NA NA NA
THR C:57 C:87 88.0 0.629 S -97.1 -9.3 NA NA NA
THR D:57 D:87 99.0 0.707 T -83.6 15.5 NA NA NA
THR E:57 E:87 97.0 0.693 S -59.3 -40.2 NA NA NA
THR F:57 F:87 82.0 0.586 T -83.8 -8.0 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 THR A:57 A:87 95.0 0.679 T -90.7 18.1 95.0 0.679 0.0 HOH
 2.300
 OG1
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 THR A:57 A:87 81.0 0.579 T -85.1 -0.3 81.0 0.579 0.0 HOH
 2.453
 OG1
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 THR A:57 A:87 93.0 0.664 T -82.9 -10.6 93.0 0.664 0.0 HOH
 2.729
 OG1
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 THR A:60 A:87 90.0 0.643 T -85.2 -11.2 90.0 0.643 0.0 HOH
 2.701
 OG1
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 THR A:60 A:87 83.0 0.593 T -80.0 -12.1 83.0 0.593 0.0 HOH
 2.790
 OG1
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 THR A:60 A:87 93.0 0.664 T -84.5 -8.6 93.0 0.664 0.0 HOH
 2.740
 OG1
 O
THR B:60 B:87 100.0 0.714 T -83.7 -3.2 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 THR A:60 A:87 92.0 0.657 T -79.4 -7.4 92.0 0.657 0.0 HOH
 2.727
 OG1
 O
THR B:60 B:87 92.0 0.657 T -83.7 -7.3 92.0 0.657 0.0 HOH
 2.910
 OG1
 O
THR C:60 C:87 88.0 0.629 T -84.5 -10.3 88.0 0.629 0.0 HOH
 2.684
 O
 O
THR D:60 D:87 93.0 0.664 T -60.6 -23.0 NA NA NA
THR E:60 E:87 98.0 0.7 T -89.7 -9.1 NA NA NA
THR F:60 F:87 78.0 0.557 S -63.8 -19.4 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 THR A:60 A:87 92.0 0.657 T -83.1 -9.8 92.0 0.657 0.0 HOH
 2.688
 O
 O
THR B:60 B:87 94.0 0.671 T -80.5 -9.3 94.0 0.671 0.0 HOH
 2.937
 O
 O
THR C:60 C:87 90.0 0.643 T -85.3 -8.3 90.0 0.643 0.0 HOH
 2.594
 O
 O
THR D:60 D:87 83.0 0.593 T -52.0 -40.9 NA NA NA
THR E:60 E:87 81.0 0.579 T -81.6 -13.5 NA NA NA
THR F:60 F:87 90.0 0.643 T -77.0 -18.4 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 THR A:60 A:87 95.0 0.679 T -87.0 -4.7 95.0 0.679 0.0 HOH
 2.439
 OG1
 O
THR B:60 B:87 89.0 0.636 T -66.9 -22.3 89.0 0.636 0.0 HOH
 4.541
 N
 O
THR C:60 C:87 96.0 0.686 T -84.7 -7.5 96.0 0.686 0.0 HOH
 3.422
 O
 O
THR D:60 D:87 104.0 0.743 T -83.7 -21.0 NA NA NA
THR E:60 E:87 96.0 0.686 T -63.5 -20.0 NA NA NA
THR F:60 F:87 91.0 0.65 S -71.4 -22.0 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 THR A:60 A:87 97.0 0.693 T -89.2 -10.6 97.0 0.693 0.0 HOH
 2.947
 O
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 THR A:60 A:87 94.0 0.671 T -87.1 -9.6 94.0 0.671 0.0 HOH
 2.718
 OG1
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 THR A:60 A:87 96.0 0.686 T -70.9 -19.4 96.0 0.686 0.0 HOH
 3.128
 O
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 THR A:60 A:87 97.0 0.693 T -83.2 -16.6 97.0 0.693 0.0 HOH
 2.620
 OG1
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 THR A:60 A:87 94.0 0.671 T -85.1 -5.6 94.0 0.671 0.0 HOH
 2.651
 OG1
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 THR A:57 A:87 94.0 0.671 T -81.9 -9.2 94.0 0.671 0.0 HOH
 3.184
 O
 O
THR B:57 B:87 84.0 0.6 T -82.7 -9.1 NA NA NA
THR C:57 C:87 98.0 0.7 T -88.5 -5.0 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:77 A:87 92.0 0.657 T -98.2 -0.7 92.0 0.657 0.0 HOH
 2.999
 O
 O
THR B:77 B:87 98.0 0.7 T -89.5 4.9 98.0 0.7 0.0 HOH
 3.868
 CG2
 O
THR C:77 C:87 92.0 0.657 T -104.8 -3.5 92.0 0.657 0.0 HOH
 3.613
 CG2
 O
THR D:77 D:87 100.0 0.714 S -84.2 46.1 100.0 0.714 0.0 HOH
 5.750
 OG1
 O
THR E:77 E:87 101.0 0.721 T -47.1 -34.4 101.0 0.721 0.0 HOH
 8.190
 O
 O
THR F:77 F:87 98.0 0.7 T -82.4 13.2 98.0 0.7 0.0 HOH
 3.161
 OG1
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:77 A:87 90.0 0.643 T -91.3 5.4 90.0 0.643 0.0 HOH
 2.726
 O
 O
THR B:77 B:87 92.0 0.657 S -87.6 3.4 92.0 0.657 0.0 HOH
 3.873
 O
 O
THR C:77 C:87 94.0 0.671 T -80.9 -14.8 94.0 0.671 0.0 HOH
 3.788
 O
 O
THR D:77 D:87 90.0 0.643 S -78.6 42.6 90.0 0.643 0.0 HOH
 3.619
 O
 O
THR E:77 E:87 89.0 0.636 T -93.0 15.7 89.0 0.636 0.0 HOH
 6.469
 N
 O
THR F:77 F:87 95.0 0.679 S -117.0 23.5 95.0 0.679 0.0 HOH
 8.158
 N
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:77 A:87 92.0 0.657 T -85.9 -5.4 92.0 0.657 0.0 HOH
 2.965
 O
 O
THR B:77 B:87 99.0 0.707 T -88.5 -7.5 99.0 0.707 0.0 HOH
 3.169
 O
 O
THR C:77 C:87 92.0 0.657 T -93.4 -3.8 92.0 0.657 0.0 HOH
 2.805
 OG1
 O
THR D:77 D:87 97.0 0.693 T -78.1 -18.8 97.0 0.693 0.0 HOH
 9.442
 CG2
 O
THR E:77 E:87 97.0 0.693 T -71.3 -5.9 97.0 0.693 0.0
THR F:77 F:87 95.0 0.679 T -77.5 -8.5 95.0 0.679 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:77 A:87 103.0 0.736 T -86.8 -0.8 103.0 0.736 0.0 HOH
 2.513
 OG1
 O
THR B:77 B:87 97.0 0.693 T -80.3 -7.0 97.0 0.693 0.0 HOH
 3.698
 O
 O
THR C:77 C:87 97.0 0.693 T -89.3 5.4 97.0 0.693 0.0 HOH
 6.789
 N
 O
THR D:77 D:87 97.0 0.693 T -87.5 4.7 97.0 0.693 0.0
THR E:77 E:87 97.0 0.693 T -88.7 -0.5 97.0 0.693 0.0 HOH
 5.363
 CG2
 O
THR F:77 F:87 105.0 0.75 S -77.7 -1.1 105.0 0.75 0.0 HOH
 8.703
 OG1
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:77 A:87 97.0 0.693 T -90.5 1.0 97.0 0.693 0.0 HOH
 3.099
 O
 O
THR B:77 B:87 95.0 0.679 T -85.2 -0.8 95.0 0.679 0.0 HOH
 3.012
 O
 O
THR C:77 C:87 90.0 0.643 T -92.3 -7.9 90.0 0.643 0.0 HOH
 3.031
 O
 O
THR D:77 D:87 88.0 0.629 T -92.2 30.4 88.0 0.629 0.0 HOH
 8.695
 O
 O
THR E:77 E:87 88.0 0.629 T -77.3 -1.0 88.0 0.629 0.0 HOH
 4.951
 CG2
 O
THR F:77 F:87 99.0 0.707 S -73.0 17.1 99.0 0.707 0.0 HOH
 8.707
 O
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:77 A:87 83.0 0.593 T -89.8 -3.7 83.0 0.593 0.0 HOH
 3.135
 O
 O
THR B:77 B:87 92.0 0.657 T -88.8 -5.3 92.0 0.657 0.0 HOH
 3.166
 O
 O
THR C:77 C:87 92.0 0.657 T -92.6 -3.1 92.0 0.657 0.0 HOH
 2.835
 OG1
 O
THR D:77 D:87 100.0 0.714 T -81.5 4.4 100.0 0.714 0.0
THR E:77 E:87 99.0 0.707 T -88.1 2.2 99.0 0.707 0.0 HOH
 6.163
 N
 O
THR F:77 F:87 92.0 0.657 S -77.1 -25.0 92.0 0.657 0.0 HOH
 5.199
 N
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:77 A:87 94.0 0.671 T -87.8 -7.3 94.0 0.671 0.0 HOH
 2.810
 OG1
 O
THR B:77 B:87 95.0 0.679 T -82.5 -8.7 95.0 0.679 0.0 HOH
 2.789
 OG1
 O
THR C:77 C:87 98.0 0.7 T -88.8 -4.7 98.0 0.7 0.0 HOH
 2.828
 O
 O
THR D:77 D:87 104.0 0.743 T -84.7 -17.3 104.0 0.743 0.0 HOH
 2.733
 OG1
 O
THR E:77 E:87 83.0 0.593 T -85.3 -6.2 83.0 0.593 0.0 HOH
 6.396
 N
 O
THR F:77 F:87 101.0 0.721 S -69.9 7.1 101.0 0.721 0.0 HOH
 3.419
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:77 A:87 95.0 0.679 T -89.0 -2.2 95.0 0.679 0.0 HOH
 2.887
 OG1
 O
THR B:77 B:87 98.0 0.7 T -86.3 -4.7 98.0 0.7 0.0 HOH
 2.734
 O
 O
THR C:77 C:87 95.0 0.679 T -89.1 -2.4 95.0 0.679 0.0 HOH
 2.982
 O
 O
THR D:77 D:87 101.0 0.721 T -81.3 1.0 101.0 0.721 0.0 HOH
 4.886
 N
 O
THR E:77 E:87 90.0 0.643 T -86.9 -1.7 90.0 0.643 0.0 HOH
 6.111
 N
 O
THR F:77 F:87 86.0 0.614 T -92.6 -19.1 86.0 0.614 0.0 HOH
 4.083
 N
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 THR A:77 A:87 91.0 0.65 T -90.2 8.5 91.0 0.65 0.0 HOH
 3.303
 O
 O
THR B:77 B:87 96.0 0.686 T -80.0 16.7 96.0 0.686 0.0 HOH
 4.253
 C
 O
THR C:77 C:87 93.0 0.664 T -68.9 -9.5 93.0 0.664 0.0 HOH
 4.664
 O
 O
THR D:77 D:87 91.0 0.65 S -90.9 43.2 91.0 0.65 0.0
THR E:77 E:87 90.0 0.643 T -60.6 -10.2 90.0 0.643 0.0
THR F:77 F:87 91.0 0.65 S -60.9 -21.0 91.0 0.65 0.0 HOH
 8.594
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 THR A:87 A:87 92.0 0.657 T -83.8 -14.5