Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11667244 . G A CCDS5985.1:NM_004462.3:c.266aGt>aAt_NP_004453.3:p.89S>N Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:59 A:89 58.0 0.504 -71.5 157.7 58.0 0.504 0.0 HOH
 2.925
 N
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 SER A:59 A:89 53.0 0.461 -67.9 154.5 53.0 0.461 0.0 HOH
 4.699
 CA
 O
SER B:59 B:89 60.0 0.522 -58.3 145.6 NA NA NA
SER C:59 C:89 63.0 0.548 -61.8 159.8 NA NA NA
SER D:59 D:89 52.0 0.452 -71.9 144.4 NA NA NA
SER E:59 E:89 66.0 0.574 -89.3 155.3 NA NA NA
SER F:59 F:89 50.0 0.435 -73.9 160.9 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:59 A:89 64.0 0.557 -77.3 152.8 64.0 0.557 0.0 HOH
 2.803
 N
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:59 A:89 63.0 0.548 -55.3 149.2 63.0 0.548 0.0 HOH
 2.609
 OG
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 SER A:59 A:89 59.0 0.513 -64.6 155.7 59.0 0.513 0.0 HOH
 2.800
 N
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:62 A:89 56.0 0.487 -59.7 155.1 56.0 0.487 0.0 HOH
 2.840
 N
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:62 A:89 59.0 0.513 -61.4 154.3 59.0 0.513 0.0 HOH
 3.217
 N
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:62 A:89 61.0 0.53 -62.7 158.4 61.0 0.53 0.0 HOH
 3.006
 N
 O
SER B:62 B:89 67.0 0.583 -64.5 146.6 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:62 A:89 49.0 0.426 -62.3 152.4 49.0 0.426 0.0 HOH
 2.656
 OG
 O
SER B:62 B:89 53.0 0.461 -57.0 154.8 53.0 0.461 0.0 HOH
 2.851
 OG
 O
SER C:62 C:89 60.0 0.522 -64.8 155.3 60.0 0.522 0.0 HOH
 2.958
 N
 O
SER D:62 D:89 71.0 0.617 -71.8 154.6 NA NA NA
SER E:62 E:89 62.0 0.539 -55.7 147.5 NA NA NA
SER F:62 F:89 56.0 0.487 -61.9 153.8 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:62 A:89 50.0 0.435 -59.6 152.8 50.0 0.435 0.0 HOH
 2.597
 OG
 O
SER B:62 B:89 51.0 0.443 -56.6 150.6 51.0 0.443 0.0 HOH
 2.851
 N
 O
SER C:62 C:89 58.0 0.504 -64.0 155.5 58.0 0.504 0.0 HOH
 3.005
 N
 O
SER D:62 D:89 52.0 0.452 -71.5 155.6 NA NA NA
SER E:62 E:89 59.0 0.513 -55.8 151.1 NA NA NA
SER F:62 F:89 52.0 0.452 -68.7 155.9 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:62 A:89 51.0 0.443 -60.0 149.4 51.0 0.443 0.0 HOH
 2.875
 N
 O
SER B:62 B:89 55.0 0.478 -64.3 151.7 55.0 0.478 0.0 HOH
 4.522
 CA
 O
SER C:62 C:89 60.0 0.522 -60.6 151.2 60.0 0.522 0.0 HOH
 3.060
 N
 O
SER D:62 D:89 80.0 0.696 -68.6 133.9 NA NA NA
SER E:62 E:89 69.0 0.6 -56.6 135.3 NA NA NA
SER F:62 F:89 73.0 0.635 -76.9 177.1 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:62 A:89 62.0 0.539 -58.1 159.0 62.0 0.539 0.0 HOH
 2.961
 N
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:62 A:89 55.0 0.478 -59.7 154.7 55.0 0.478 0.0 HOH
 2.875
 N
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:62 A:89 63.0 0.548 -69.2 154.3 63.0 0.548 0.0 HOH
 3.456
 CB
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:62 A:89 63.0 0.548 -58.7 153.0 63.0 0.548 0.0 HOH
 3.573
 CB
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:62 A:89 56.0 0.487 -69.9 156.9 56.0 0.487 0.0 HOH
 2.552
 OG
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 SER A:59 A:89 50.0 0.435 -77.2 155.6 50.0 0.435 0.0 HOH
 5.466
 N
 O
SER B:59 B:89 50.0 0.435 -51.6 136.7 NA NA NA
SER C:59 C:89 72.0 0.626 -65.7 129.0 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:79 A:89 58.0 0.504 -59.6 157.1 58.0 0.504 0.0 HOH
 3.288
 OG
 O
SER B:79 B:89 60.0 0.522 -66.8 159.9 60.0 0.522 0.0 HOH
 2.647
 N
 O
SER C:79 C:89 52.0 0.452 -46.4 152.6 52.0 0.452 0.0 HOH
 3.779
 OG
 O
SER D:79 D:89 57.0 0.496 -65.3 137.7 57.0 0.496 0.0 HOH
 3.252
 CA
 O
SER E:79 E:89 46.0 0.4 -78.6 150.7 46.0 0.4 0.0 HOH
 6.427
 CA
 O
SER F:79 F:89 47.0 0.409 -43.6 151.8 47.0 0.409 0.0 HOH
 4.975
 CB
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:79 A:89 46.0 0.4 -50.1 149.0 46.0 0.4 0.0 HOH
 3.539
 N
 O
SER B:79 B:89 63.0 0.548 -56.5 153.9 63.0 0.548 0.0 HOH
 2.966
 OG
 O
SER C:79 C:89 51.0 0.443 -60.7 147.9 51.0 0.443 0.0 HOH
 2.892
 OG
 O
SER D:79 D:89 56.0 0.487 -56.4 137.2 56.0 0.487 0.0 HOH
 4.839
 N
 O
SER E:79 E:89 64.0 0.557 -51.9 152.6 64.0 0.557 0.0 HOH
 4.884
 C
 O
SER F:79 F:89 44.0 0.383 -63.5 -145.5 44.0 0.383 0.0 HOH
 5.766
 O
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:79 A:89 50.0 0.435 -57.4 157.0 50.0 0.435 0.0 HOH
 3.014
 N
 O
SER B:79 B:89 59.0 0.513 -56.7 153.9 59.0 0.513 0.0 HOH
 2.814
 N
 O
SER C:79 C:89 53.0 0.461 -61.9 153.1 53.0 0.461 0.0 HOH
 2.786
 N
 O
SER D:79 D:89 52.0 0.452 -66.6 148.4 52.0 0.452 0.0
SER E:79 E:89 55.0 0.478 -43.5 151.8 55.0 0.478 0.0
SER F:79 F:89 47.0 0.409 -58.7 153.6 47.0 0.409 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:79 A:89 49.0 0.426 -63.2 153.7 49.0 0.426 0.0 HOH
 3.092
 N
 O
SER B:79 B:89 58.0 0.504 -61.1 155.4 58.0 0.504 0.0 HOH
 3.188
 N
 O
SER C:79 C:89 58.0 0.504 -59.8 153.6 58.0 0.504 0.0 HOH
 2.971
 OG
 O
SER D:79 D:89 58.0 0.504 -70.1 135.0 58.0 0.504 0.0
SER E:79 E:89 39.0 0.339 -49.3 148.9 39.0 0.339 0.0
SER F:79 F:89 45.0 0.391 -59.3 152.0 45.0 0.391 0.0
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:79 A:89 54.0 0.47 -62.6 155.0 54.0 0.47 0.0 HOH
 3.292
 N
 O
SER B:79 B:89 62.0 0.539 -57.3 157.5 62.0 0.539 0.0 HOH
 2.944
 N
 O
SER C:79 C:89 57.0 0.496 -58.4 156.7 57.0 0.496 0.0 HOH
 2.884
 OG
 O
SER D:79 D:89 61.0 0.53 -49.5 132.0 61.0 0.53 0.0 HOH
 2.917
 OG
 O
SER E:79 E:89 58.0 0.504 -59.6 143.8 58.0 0.504 0.0 HOH
 3.280
 CA
 O
SER F:79 F:89 47.0 0.409 -61.8 125.2 47.0 0.409 0.0 HOH
 3.654
 OG
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:79 A:89 50.0 0.435 -61.1 155.3 50.0 0.435 0.0 HOH
 3.101
 N
 O
SER B:79 B:89 56.0 0.487 -59.2 154.8 56.0 0.487 0.0 HOH
 3.107
 N
 O
SER C:79 C:89 52.0 0.452 -62.0 150.4 52.0 0.452 0.0 HOH
 2.936
 N
 O
SER D:79 D:89 49.0 0.426 -62.8 137.6 49.0 0.426 0.0 HOH
 7.147
 O
 O
SER E:79 E:89 49.0 0.426 -51.7 141.3 49.0 0.426 0.0 HOH
 4.410
 C
 O
SER F:79 F:89 50.0 0.435 -60.0 156.1 50.0 0.435 0.0 HOH
 4.097
 C
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:79 A:89 49.0 0.426 -64.9 151.8 49.0 0.426 0.0 HOH
 3.042
 N
 O
SER B:79 B:89 57.0 0.496 -58.7 150.7 57.0 0.496 0.0 HOH
 3.077
 N
 O
SER C:79 C:89 51.0 0.443 -64.1 153.8 51.0 0.443 0.0 HOH
 2.655
 OG
 O
SER D:79 D:89 51.0 0.443 -63.5 127.9 51.0 0.443 0.0 HOH
 5.299
 N
 O
SER E:79 E:89 52.0 0.452 -62.5 145.9 52.0 0.452 0.0 HOH
 4.471
 C
 O
SER F:79 F:89 49.0 0.426 -78.1 154.8 49.0 0.426 0.0 HOH
 4.185
 N
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:79 A:89 51.0 0.443 -57.3 153.7 51.0 0.443 0.0 HOH
 2.814
 N
 O
SER B:79 B:89 59.0 0.513 -61.4 156.6 59.0 0.513 0.0 HOH
 2.898
 OG
 O
SER C:79 C:89 52.0 0.452 -60.1 153.3 52.0 0.452 0.0 HOH
 2.869
 N
 O
SER D:79 D:89 49.0 0.426 -61.2 151.7 49.0 0.426 0.0 HOH
 3.512
 CA
 O
SER E:79 E:89 46.0 0.4 -58.2 150.3 46.0 0.4 0.0 HOH
 4.871
 C
 O
SER F:79 F:89 58.0 0.504 -69.9 149.7 58.0 0.504 0.0 HOH
 4.764
 N
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 SER A:79 A:89 51.0 0.443 -54.3 157.9 51.0 0.443 0.0 HOH
 3.757
 N
 O
SER B:79 B:89 63.0 0.548 -57.0 158.5 63.0 0.548 0.0 HOH
 4.004
 N
 O
SER C:79 C:89 55.0 0.478 -63.8 145.4 55.0 0.478 0.0 HOH
 3.903
 CA
 O
SER D:79 D:89 79.0 0.687 -54.3 129.1 79.0 0.687 0.0 HOH
 6.856
 O
 O
SER E:79 E:89 50.0 0.435 -69.9 155.3 50.0 0.435 0.0 HOH
 9.757
 OG
 O
SER F:79 F:89 45.0 0.391 -102.8 153.4 45.0 0.391 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 SER A:89 A:89 61.0 0.53 -63.1 151.0