Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11667271 . A C CCDS5985.1:NM_004462.3:c.293cAc>cCc_NP_004453.3:p.98H>P Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 HIS A:68 A:98 76.0 0.39 H -60.4 -43.1 76.0 0.39 0.0 HOH
 2.666
 O
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 HIS A:68 A:98 75.0 0.385 H -54.8 -55.1 75.0 0.385 0.0 HOH
 3.381
 O
 O
HIS B:68 B:98 80.0 0.41 H -54.2 -39.6 NA NA NA
HIS C:68 C:98 77.0 0.395 H -60.6 -41.3 NA NA NA
HIS D:68 D:98 80.0 0.41 H -51.3 -30.1 NA NA NA
HIS E:68 E:98 77.0 0.395 H -39.7 -58.7 NA NA NA
HIS F:68 F:98 68.0 0.349 H -42.9 -55.8 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 HIS A:68 A:98 80.0 0.41 H -56.4 -39.2 80.0 0.41 0.0 HOH
 2.811
 NE2
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 HIS A:68 A:98 78.0 0.4 H -62.8 -36.1 78.0 0.4 0.0 HOH
 2.729
 O
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 HIS A:68 A:98 81.0 0.415 H -63.0 -41.0 81.0 0.415 0.0 HOH
 2.716
 O
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 HIS A:71 A:98 78.0 0.4 H -62.7 -37.4 78.0 0.4 0.0 HOH
 2.740
 O
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 HIS A:71 A:98 81.0 0.415 H -60.8 -39.8 81.0 0.415 0.0 HOH
 2.572
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 HIS A:71 A:98 81.0 0.415 H -67.8 -33.6 81.0 0.415 0.0 NI
HOH
 2.195
2.765
 ND1
NE2
 NI
O
HIS B:71 B:98 77.0 0.395 H -66.8 -37.4 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 HIS A:71 A:98 78.0 0.4 H -60.7 -40.1 78.0 0.4 0.0 HOH
 2.712
 O
 O
HIS B:71 B:98 78.0 0.4 H -60.3 -37.3 78.0 0.4 0.0 HOH
 2.423
 O
 O
HIS C:71 C:98 79.0 0.405 H -67.4 -36.8 79.0 0.405 0.0 HOH
 2.826
 NE2
 O
HIS D:71 D:98 74.0 0.379 H -57.5 -38.5 NA NA NA
HIS E:71 E:98 72.0 0.369 H -59.7 -37.2 NA NA NA
HIS F:71 F:98 75.0 0.385 H -63.7 -44.4 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 HIS A:71 A:98 76.0 0.39 H -60.6 -41.4 76.0 0.39 0.0 HOH
 2.728
 O
 O
HIS B:71 B:98 78.0 0.4 H -64.1 -38.9 78.0 0.4 0.0 HOH
 2.617
 O
 O
HIS C:71 C:98 78.0 0.4 H -64.7 -39.9 78.0 0.4 0.0 HOH
 2.673
 O
 O
HIS D:71 D:98 74.0 0.379 H -63.3 -45.9 NA NA NA
HIS E:71 E:98 74.0 0.379 H -66.8 -31.9 NA NA NA
HIS F:71 F:98 73.0 0.374 H -60.2 -37.4 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 HIS A:71 A:98 79.0 0.405 H -63.6 -44.0 79.0 0.405 0.0 HOH
 2.743
 O
 O
HIS B:71 B:98 73.0 0.374 H -68.6 -42.5 73.0 0.374 0.0 HOH
 3.065
 ND1
 O
HIS C:71 C:98 82.0 0.421 H -57.6 -40.7 82.0 0.421 0.0 HOH
 2.772
 O
 O
HIS D:71 D:98 79.0 0.405 H -61.8 -43.9 NA NA NA
HIS E:71 E:98 70.0 0.359 H -68.4 -33.1 NA NA NA
HIS F:71 F:98 82.0 0.421 H -64.5 -48.0 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 HIS A:71 A:98 80.0 0.41 H -61.0 -40.3 80.0 0.41 0.0 HOH
 2.618
 O
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 HIS A:71 A:98 81.0 0.415 H -64.6 -37.7 81.0 0.415 0.0 HOH
 2.689
 O
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 HIS A:71 A:98 78.0 0.4 H -63.6 -36.3 78.0 0.4 0.0 HOH
 2.998
 O
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 HIS A:71 A:98 74.0 0.379 H -61.7 -38.8 74.0 0.379 0.0 HOH
 2.629
 O
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 HIS A:71 A:98 73.0 0.374 H -58.9 -38.8 73.0 0.374 0.0 HOH
 2.650
 O
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 HIS A:68 A:98 62.0 0.318 H -67.0 -42.4 62.0 0.318 0.0 HOH
 2.701
 O
 O
HIS B:68 B:98 69.0 0.354 H -66.1 -40.4 NA NA NA
HIS C:68 C:98 65.0 0.333 H -67.4 -43.4 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 HIS A:88 A:98 79.0 0.405 H -59.6 -42.1 79.0 0.405 0.0 HOH
 7.028
 C
 O
HIS B:88 B:98 77.0 0.395 H -68.2 -38.2 77.0 0.395 0.0 HOH
 3.334
 O
 O
HIS C:88 C:98 76.0 0.39 H -47.3 -36.0 76.0 0.39 0.0 HOH
 3.557
 CE1
 O
HIS D:88 D:98 73.0 0.374 H -67.8 -38.2 73.0 0.374 0.0 HOH
 2.640
 NE2
 O
HIS E:88 E:98 64.0 0.328 H -63.9 -44.5 64.0 0.328 0.0
HIS F:88 F:98 72.0 0.369 H -50.8 -37.6 72.0 0.369 0.0
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 HIS A:88 A:98 75.0 0.385 H -59.5 -45.2 75.0 0.385 0.0 HOH
 6.708
 O
 O
HIS B:88 B:98 83.0 0.426 H -67.7 -42.8 83.0 0.426 0.0 HOH
 3.435
 O
 O
HIS C:88 C:98 79.0 0.405 H -59.6 -41.8 79.0 0.405 0.0 HOH
 3.912
 ND1
 O
HIS D:88 D:98 75.0 0.385 H -71.3 -23.2 75.0 0.385 0.0 HOH
 3.572
 CE1
 O
HIS E:88 E:98 77.0 0.395 H -58.8 -45.8 77.0 0.395 0.0 HOH
 9.282
 O
 O
HIS F:88 F:98 82.0 0.421 H -49.6 -30.7 82.0 0.421 0.0 HOH
 3.998
 O
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 HIS A:88 A:98 76.0 0.39 H -66.2 -42.1 76.0 0.39 0.0 HOH
 2.771
 O
 O
HIS B:88 B:98 80.0 0.41 H -62.7 -37.9 80.0 0.41 0.0 HOH
 2.625
 O
 O
HIS C:88 C:98 76.0 0.39 H -69.7 -41.1 76.0 0.39 0.0 HOH
 3.483
 O
 O
HIS D:88 D:98 69.0 0.354 H -66.5 -39.2 69.0 0.354 0.0 HOH
 2.833
 ND1
 O
HIS E:88 E:98 70.0 0.359 H -67.8 -38.5 70.0 0.359 0.0
HIS F:88 F:98 66.0 0.338 H -55.6 -37.6 66.0 0.338 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 HIS A:88 A:98 75.0 0.385 H -66.6 -36.6 75.0 0.385 0.0 HOH
 2.729
 O
 O
HIS B:88 B:98 76.0 0.39 H -60.3 -31.9 76.0 0.39 0.0 HOH
 2.790
 ND1
 O
HIS C:88 C:98 76.0 0.39 H -66.8 -42.6 76.0 0.39 0.0 HOH
 7.452
 N
 O
HIS D:88 D:98 73.0 0.374 H -63.2 -36.6 73.0 0.374 0.0 HOH
 3.712
 O
 O
HIS E:88 E:98 75.0 0.385 H -68.8 -34.5 75.0 0.385 0.0 HOH
 3.564
 O
 O
HIS F:88 F:98 78.0 0.4 H -62.3 -35.9 78.0 0.4 0.0 HOH
 3.373
 O
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 HIS A:88 A:98 79.0 0.405 H -65.1 -40.0 79.0 0.405 0.0 HOH
 2.788
 NE2
 O
HIS B:88 B:98 76.0 0.39 H -64.4 -37.9 76.0 0.39 0.0 HOH
 2.548
 ND1
 O
HIS C:88 C:98 76.0 0.39 H -59.0 -40.0 76.0 0.39 0.0 HOH
 2.549
 O
 O
HIS D:88 D:98 64.0 0.328 H -74.2 -36.8 64.0 0.328 0.0 HOH
 2.801
 NE2
 O
HIS E:88 E:98 67.0 0.344 H -74.6 -37.1 67.0 0.344 0.0 HOH
 3.315
 NE2
 O
HIS F:88 F:98 76.0 0.39 H -58.8 -33.8 76.0 0.39 0.0 HOH
 3.664
 O
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 HIS A:88 A:98 78.0 0.4 H -60.5 -41.2 78.0 0.4 0.0 HOH
 2.643
 O
 O
HIS B:88 B:98 78.0 0.4 H -67.1 -34.2 78.0 0.4 0.0 HOH
 2.716
 ND1
 O
HIS C:88 C:98 80.0 0.41 H -65.2 -36.6 80.0 0.41 0.0 HOH
 3.589
 O
 O
HIS D:88 D:98 75.0 0.385 H -63.8 -37.7 75.0 0.385 0.0 HOH
 2.880
 NE2
 O
HIS E:88 E:98 73.0 0.374 H -65.0 -35.8 73.0 0.374 0.0
HIS F:88 F:98 73.0 0.374 H -63.5 -33.0 73.0 0.374 0.0
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 HIS A:88 A:98 77.0 0.395 H -64.4 -40.9 77.0 0.395 0.0 HOH
 2.722
 O
 O
HIS B:88 B:98 68.0 0.349 H -61.2 -36.0 68.0 0.349 0.0 HOH
 2.685
 ND1
 O
HIS C:88 C:98 77.0 0.395 H -67.5 -33.7 77.0 0.395 0.0 HOH
 3.035
 NE2
 O
HIS D:88 D:98 65.0 0.333 H -64.8 -37.7 65.0 0.333 0.0 HOH
 2.872
 NE2
 O
HIS E:88 E:98 73.0 0.374 H -63.9 -36.8 73.0 0.374 0.0 HOH
 3.589
 O
 O
HIS F:88 F:98 75.0 0.385 H -64.6 -32.1 75.0 0.385 0.0 HOH
 3.648
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 HIS A:88 A:98 76.0 0.39 H -61.1 -41.4 76.0 0.39 0.0 HOH
 2.710
 O
 O
HIS B:88 B:98 80.0 0.41 H -63.9 -38.7 80.0 0.41 0.0 HOH
 2.707
 ND1
 O
HIS C:88 C:98 80.0 0.41 H -66.5 -35.5 80.0 0.41 0.0 HOH
 2.503
 O
 O
HIS D:88 D:98 71.0 0.364 H -63.0 -37.5 71.0 0.364 0.0 HOH
 2.444
 O
 O
HIS E:88 E:98 76.0 0.39 H -67.1 -36.7 76.0 0.39 0.0 HOH
 2.478
 O
 O
HIS F:88 F:98 72.0 0.369 H -62.9 -31.1 72.0 0.369 0.0
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 HIS A:88 A:98 78.0 0.4 H -71.2 -33.7 78.0 0.4 0.0 HOH
 7.103
 O
 O
HIS B:88 B:98 78.0 0.4 H -63.9 -30.1 78.0 0.4 0.0 HOH
 4.004
 CE1
 O
HIS C:88 C:98 77.0 0.395 H -64.6 -34.1 77.0 0.395 0.0 HOH
 8.433
 CE1
 O
HIS D:88 D:98 74.0 0.379 H -72.1 -19.7 74.0 0.379 0.0 HOH
 3.252
 CE1
 O
HIS E:88 E:98 80.0 0.41 H -63.5 -35.6 80.0 0.41 0.0
HIS F:88 F:98 72.0 0.369 H -64.8 -30.6 72.0 0.369 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 HIS A:98 A:98 73.0 0.374 H -58.4 -40.1