Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11667283 . C A CCDS5985.1:NM_004462.3:c.305tCt>tAt_NP_004453.3:p.102S>Y Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:72 A:102 40.0 0.348 H -77.6 -32.1 40.0 0.348 0.0 HOH
 2.413
 OG
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 SER A:72 A:102 36.0 0.313 H -71.0 -29.6 36.0 0.313 0.0 HOH
 5.586
 N
 O
SER B:72 B:102 30.0 0.261 H -73.1 -31.0 NA NA NA
SER C:72 C:102 46.0 0.4 H -86.9 -18.6 NA NA NA
SER D:72 D:102 39.0 0.339 H -87.5 -20.5 NA NA NA
SER E:72 E:102 50.0 0.435 G -70.1 -30.5 NA NA NA
SER F:72 F:102 51.0 0.443 T -79.5 -28.1 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:72 A:102 48.0 0.417 H -72.3 -33.6 48.0 0.417 0.0 HOH
 3.153
 O
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:72 A:102 41.0 0.357 H -74.3 -33.6 41.0 0.357 0.0 HOH
 2.722
 OG
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 SER A:72 A:102 41.0 0.357 H -71.2 -32.2 41.0 0.357 0.0 HOH
 2.943
 O
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:75 A:102 46.0 0.4 H -77.4 -22.4 46.0 0.4 0.0 HOH
 3.175
 OG
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:75 A:102 31.0 0.27 H -75.2 -28.4 31.0 0.27 0.0 HOH
 3.080
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:75 A:102 35.0 0.304 H -79.4 -21.3 35.0 0.304 0.0 HOH
 2.925
 O
 O
SER B:75 B:102 30.0 0.261 H -76.1 -26.8 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:75 A:102 37.0 0.322 H -78.0 -22.7 37.0 0.322 0.0 HOH
 2.560
 OG
 O
SER B:75 B:102 24.0 0.209 H -67.2 -27.9 24.0 0.209 0.0 HOH
 5.379
 N
 O
SER C:75 C:102 48.0 0.417 H -80.0 -25.0 48.0 0.417 0.0 HOH
 2.623
 OG
 O
SER D:75 D:102 48.0 0.417 H -73.6 -35.8 NA NA NA
SER E:75 E:102 36.0 0.313 H -73.1 -23.2 NA NA NA
SER F:75 F:102 32.0 0.278 G -79.3 -26.7 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:75 A:102 44.0 0.383 H -65.2 -33.9 44.0 0.383 0.0 HOH
 2.838
 O
 O
SER B:75 B:102 36.0 0.313 H -79.8 -24.3 36.0 0.313 0.0 HOH
 3.745
 N
 O
SER C:75 C:102 48.0 0.417 H -81.5 -26.0 48.0 0.417 0.0 HOH
 2.550
 OG
 O
SER D:75 D:102 37.0 0.322 H -85.3 -25.0 NA NA NA
SER E:75 E:102 57.0 0.496 H -70.6 -33.6 NA NA NA
SER F:75 F:102 40.0 0.348 H -81.1 -30.3 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:75 A:102 39.0 0.339 H -69.2 -31.6 39.0 0.339 0.0 HOH
 5.427
 N
 O
SER B:75 B:102 35.0 0.304 H -86.6 -21.6 35.0 0.304 0.0 HOH
 5.470
 N
 O
SER C:75 C:102 45.0 0.391 H -83.8 -17.9 45.0 0.391 0.0 HOH
 2.815
 O
 O
SER D:75 D:102 37.0 0.322 H -74.5 -44.7 NA NA NA
SER E:75 E:102 50.0 0.435 H -78.2 -26.4 NA NA NA
SER F:75 F:102 43.0 0.374 H -84.7 -19.9 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:75 A:102 35.0 0.304 H -77.8 -22.3 35.0 0.304 0.0 HOH
 4.038
 CA
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:75 A:102 46.0 0.4 H -77.8 -21.7 46.0 0.4 0.0 HOH
 3.048
 OG
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:75 A:102 34.0 0.296 H -77.3 -29.0 34.0 0.296 0.0 HOH
 3.065
 OG
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:75 A:102 35.0 0.304 H -79.5 -24.9 35.0 0.304 0.0 HOH
 2.665
 O
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:75 A:102 38.0 0.33 H -76.1 -24.0 38.0 0.33 0.0 HOH
 2.637
 OG
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 SER A:72 A:102 41.0 0.357 H -68.0 -29.1 41.0 0.357 0.0 HOH
 4.584
 OG
 O
SER B:72 B:102 39.0 0.339 H -77.1 -36.3 NA NA NA
SER C:72 C:102 29.0 0.252 H -76.4 -26.7 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:92 A:102 36.0 0.313 H -78.0 -27.7 36.0 0.313 0.0 HOH
 3.500
 O
 O
SER B:92 B:102 43.0 0.374 H -74.8 -27.8 43.0 0.374 0.0 HOH
 3.106
 OG
 O
SER C:92 C:102 24.0 0.209 H -79.9 -25.5 24.0 0.209 0.0 HOH
 7.080
 O
 O
SER D:92 D:102 34.0 0.296 G -75.7 -30.6 34.0 0.296 0.0 HOH
 7.873
 OG
 O
SER E:92 E:102 47.0 0.409 T -156.0 61.2 47.0 0.409 0.0
SER F:92 F:102 40.0 0.348 H -86.0 -28.7 40.0 0.348 0.0
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:92 A:102 36.0 0.313 H -75.8 -20.5 36.0 0.313 0.0 HOH
 4.716
 OG
 O
SER B:92 B:102 46.0 0.4 H -94.0 -20.7 46.0 0.4 0.0 HOH
 3.456
 O
 O
SER C:92 C:102 27.0 0.235 H -87.5 -20.0 27.0 0.235 0.0 HOH
 3.804
 OG
 O
SER D:92 D:102 39.0 0.339 H -75.5 -29.1 39.0 0.339 0.0 HOH
 3.640
 OG
 O
SER E:92 E:102 33.0 0.287 H -85.8 -24.3 33.0 0.287 0.0 HOH
 7.964
 O
 O
SER F:92 F:102 36.0 0.313 H -68.1 -38.1 36.0 0.313 0.0 HOH
 7.532
 O
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:92 A:102 36.0 0.313 H -76.1 -26.6 36.0 0.313 0.0 HOH
 3.658
 N
 O
SER B:92 B:102 49.0 0.426 H -83.2 -24.9 49.0 0.426 0.0 HOH
 2.732
 OG
 O
SER C:92 C:102 23.0 0.2 H -78.5 -19.1 23.0 0.2 0.0 HOH
 5.317
 N
 O
SER D:92 D:102 35.0 0.304 H -70.2 -25.0 35.0 0.304 0.0 HOH
 2.959
 OG
 O
SER E:92 E:102 36.0 0.313 H -91.9 -26.0 36.0 0.313 0.0
SER F:92 F:102 34.0 0.296 H -87.1 -24.5 34.0 0.296 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:92 A:102 36.0 0.313 H -77.8 -30.1 36.0 0.313 0.0 HOH
 3.557
 CA
 O
SER B:92 B:102 47.0 0.409 H -87.7 -25.0 47.0 0.409 0.0 HOH
 3.358
 OG
 O
SER C:92 C:102 37.0 0.322 H -79.5 -18.4 37.0 0.322 0.0 HOH
 6.731
 O
 O
SER D:92 D:102 48.0 0.417 H -64.7 -31.3 48.0 0.417 0.0 HOH
 5.284
 N
 O
SER E:92 E:102 37.0 0.322 H -83.4 -23.4 37.0 0.322 0.0 HOH
 4.097
 O
 O
SER F:92 F:102 35.0 0.304 H -73.4 -24.7 35.0 0.304 0.0 HOH
 5.214
 N
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:92 A:102 37.0 0.322 H -74.8 -27.7 37.0 0.322 0.0 HOH
 4.143
 CB
 O
SER B:92 B:102 46.0 0.4 H -86.1 -23.8 46.0 0.4 0.0 HOH
 2.840
 OG
 O
SER C:92 C:102 39.0 0.339 H -80.4 -19.4 39.0 0.339 0.0 HOH
 4.278
 CA
 O
SER D:92 D:102 48.0 0.417 H -87.2 -18.4 48.0 0.417 0.0 HOH
 5.475
 N
 O
SER E:92 E:102 34.0 0.296 H -88.2 -28.6 34.0 0.296 0.0 HOH
 4.593
 CA
 O
SER F:92 F:102 31.0 0.27 H -88.8 -27.3 31.0 0.27 0.0 HOH
 5.335
 N
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:92 A:102 36.0 0.313 H -75.9 -27.0 36.0 0.313 0.0 HOH
 2.871
 O
 O
SER B:92 B:102 47.0 0.409 H -87.8 -25.1 47.0 0.409 0.0 HOH
 2.837
 O
 O
SER C:92 C:102 24.0 0.209 H -75.9 -22.7 24.0 0.209 0.0 HOH
 3.274
 OG
 O
SER D:92 D:102 35.0 0.304 H -79.3 -23.7 35.0 0.304 0.0 HOH
 5.328
 N
 O
SER E:92 E:102 42.0 0.365 H -89.3 -20.8 42.0 0.365 0.0
SER F:92 F:102 30.0 0.261 H -78.5 -34.9 30.0 0.261 0.0
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:92 A:102 37.0 0.322 H -75.7 -23.9 37.0 0.322 0.0 HOH
 2.807
 O
 O
SER B:92 B:102 47.0 0.409 H -85.8 -28.2 47.0 0.409 0.0 HOH
 2.756
 OG
 O
SER C:92 C:102 23.0 0.2 H -76.9 -25.6 23.0 0.2 0.0 HOH
 3.893
 CB
 O
SER D:92 D:102 33.0 0.287 H -72.7 -26.1 33.0 0.287 0.0 HOH
 4.218
 OG
 O
SER E:92 E:102 32.0 0.278 H -77.1 -26.7 32.0 0.278 0.0 HOH
 5.292
 N
 O
SER F:92 F:102 33.0 0.287 H -81.8 -30.1 33.0 0.287 0.0 HOH
 4.345
 N
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:92 A:102 37.0 0.322 H -75.0 -26.1 37.0 0.322 0.0 HOH
 2.662
 OG
 O
SER B:92 B:102 47.0 0.409 H -82.4 -26.7 47.0 0.409 0.0 HOH
 2.784
 OG
 O
SER C:92 C:102 25.0 0.217 H -76.4 -19.9 25.0 0.217 0.0 HOH
 5.187
 N
 O
SER D:92 D:102 35.0 0.304 H -73.7 -25.4 35.0 0.304 0.0 HOH
 5.224
 N
 O
SER E:92 E:102 36.0 0.313 H -80.4 -19.5 36.0 0.313 0.0 HOH
 5.478
 N
 O
SER F:92 F:102 34.0 0.296 H -86.1 -29.6 34.0 0.296 0.0
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 SER A:92 A:102 34.0 0.296 H -84.1 -25.9 34.0 0.296 0.0 HOH
 5.191
 OG
 O
SER B:92 B:102 44.0 0.383 H -85.8 -26.4 44.0 0.383 0.0 HOH
 2.971
 O
 O
SER C:92 C:102 23.0 0.2 H -75.7 -21.1 23.0 0.2 0.0
SER D:92 D:102 32.0 0.278 T -86.7 -29.3 32.0 0.278 0.0
SER E:92 E:102 35.0 0.304 H -85.1 -33.9 35.0 0.304 0.0
SER F:92 F:102 38.0 0.33 G -80.4 -25.1 38.0 0.33 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 SER A:102 A:102 32.0 0.278 H -73.7 -27.5