Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11667313 . T A CCDS5985.1:NM_004462.3:c.335aTg>aAg_NP_004453.3:p.112M>K Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 MET A:82 A:112 116.0 0.627 -98.2 3.7 116.0 0.627 0.0 HOH
 2.737
 N
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 MET A:82 A:112 101.0 0.546 -101.9 -8.8 101.0 0.546 0.0 HOH
 3.303
 CG
 O
MET B:82 B:112 94.0 0.508 -115.5 11.1 NA NA NA
MET C:82 C:112 102.0 0.551 -123.2 19.5 NA NA NA
MET D:82 D:112 97.0 0.524 -114.1 -6.5 NA NA NA
MET E:82 E:112 100.0 0.541 -98.1 -15.6 NA NA NA
MET F:82 F:112 115.0 0.622 -89.6 161.6 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 MET A:82 A:112 101.0 0.546 -106.5 -11.7 101.0 0.546 0.0 HOH
 2.889
 N
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 MET A:82 A:112 95.0 0.514 -111.7 2.2 95.0 0.514 0.0 HOH
 2.723
 N
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 MET A:82 A:112 105.0 0.568 -102.2 -6.0 105.0 0.568 0.0 HOH
 2.669
 N
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 MET A:85 A:112 95.0 0.514 -105.0 1.8 95.0 0.514 0.0 HOH
 2.820
 N
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 MET A:85 A:112 90.0 0.486 -106.7 3.5 90.0 0.486 0.0 HOH
 2.827
 N
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 MET A:85 A:112 88.0 0.476 -101.9 -1.2 88.0 0.476 0.0 HOH
 2.796
 N
 O
MET B:85 B:112 98.0 0.53 -108.9 5.8 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 MET A:85 A:112 79.0 0.427 -105.4 3.4 79.0 0.427 0.0 HOH
 2.853
 N
 O
MET B:85 B:112 91.0 0.492 -107.9 2.9 91.0 0.492 0.0 HOH
 2.676
 N
 O
MET C:85 C:112 88.0 0.476 -105.3 3.1 88.0 0.476 0.0 HOH
 2.821
 O
 O
MET D:85 D:112 78.0 0.422 -107.2 -8.4 NA NA NA
MET E:85 E:112 95.0 0.514 -98.9 -0.4 NA NA NA
MET F:85 F:112 89.0 0.481 -117.9 -9.6 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 MET A:85 A:112 75.0 0.405 -103.3 1.9 75.0 0.405 0.0 HOH
 2.893
 N
 O
MET B:85 B:112 91.0 0.492 -108.3 2.5 91.0 0.492 0.0 HOH
 2.709
 O
 O
MET C:85 C:112 105.0 0.568 -105.7 0.6 105.0 0.568 0.0 HOH
 2.672
 O
 O
MET D:85 D:112 88.0 0.476 -93.7 -7.1 NA NA NA
MET E:85 E:112 81.0 0.438 -108.1 1.0 NA NA NA
MET F:85 F:112 120.0 0.649 -110.9 -0.5 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 MET A:85 A:112 90.0 0.486 -101.5 7.6 90.0 0.486 0.0 HOH
 3.183
 C
 O
MET B:85 B:112 93.0 0.503 -99.5 -3.0 93.0 0.503 0.0 HOH
 2.998
 C
 O
MET C:85 C:112 116.0 0.627 -106.0 8.7 116.0 0.627 0.0 HOH
 2.782
 N
 O
MET D:85 D:112 83.0 0.449 -86.3 -11.0 NA NA NA
MET E:85 E:112 80.0 0.432 -93.9 9.6 NA NA NA
MET F:85 F:112 119.0 0.643 -103.2 25.2 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 MET A:85 A:112 110.0 0.595 -112.0 13.9 110.0 0.595 0.0
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 MET A:85 A:112 95.0 0.514 -102.0 1.8 95.0 0.514 0.0 HOH
 2.707
 O
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 MET A:85 A:112 111.0 0.6 -116.5 2.2 111.0 0.6 0.0 HOH
 3.038
 O
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 MET A:85 A:112 113.0 0.611 -104.8 4.7 113.0 0.611 0.0 HOH
 2.670
 N
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 MET A:85 A:112 112.0 0.605 -106.4 -1.6 112.0 0.605 0.0 HOH
 2.560
 N
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 MET A:82 A:112 74.0 0.4 -100.4 -7.1 74.0 0.4 0.0 HOH
 7.457
 C
 O
MET B:82 B:112 82.0 0.443 -96.6 -4.5 NA NA NA
MET C:82 C:112 104.0 0.562 -93.8 -5.7 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 MET A:102 A:112 82.0 0.443 -110.7 -8.4 82.0 0.443 0.0 HOH
 3.547
 O
 O
MET B:102 B:112 93.0 0.503 -105.9 -7.9 93.0 0.503 0.0 HOH
 2.842
 N
 O
MET C:102 C:112 82.0 0.443 -103.9 1.8 82.0 0.443 0.0 HOH
 3.611
 CB
 O
MET D:102 D:112 78.0 0.422 -95.4 -16.9 78.0 0.422 0.0 HOH
 4.875
 O
 O
MET E:102 E:112 87.0 0.47 -54.8 -17.6 87.0 0.47 0.0 HOH
 4.008
 CE
 O
MET F:102 F:112 93.0 0.503 -118.6 -34.2 93.0 0.503 0.0 HOH
 7.016
 O
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 MET A:102 A:112 86.0 0.465 -101.7 -13.9 86.0 0.465 0.0 HOH
 3.320
 O
 O
MET B:102 B:112 89.0 0.481 -116.2 9.5 89.0 0.481 0.0 HOH
 3.186
 N
 O
MET C:102 C:112 89.0 0.481 -94.5 0.5 89.0 0.481 0.0 HOH
 3.775
 CE
 O
MET D:102 D:112 84.0 0.454 -101.3 5.3 84.0 0.454 0.0 HOH
 3.921
 CE
 O
MET E:102 E:112 83.0 0.449 -107.0 -13.6 83.0 0.449 0.0 HOH
 8.278
 N
 O
MET F:102 F:112 97.0 0.524 T -85.0 28.3 97.0 0.524 0.0 HOH
 4.196
 O
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 MET A:102 A:112 85.0 0.459 -105.1 -3.1 85.0 0.459 0.0 HOH
 2.817
 N
 O
MET B:102 B:112 93.0 0.503 -104.9 4.2 93.0 0.503 0.0 HOH
 2.895
 N
 O
MET C:102 C:112 83.0 0.449 -117.0 10.1 83.0 0.449 0.0 HOH
 3.022
 C
 O
MET D:102 D:112 79.0 0.427 -109.9 7.2 79.0 0.427 0.0 HOH
 2.841
 C
 O
MET E:102 E:112 86.0 0.465 -110.4 3.2 86.0 0.465 0.0
MET F:102 F:112 88.0 0.476 -95.1 17.9 88.0 0.476 0.0 HOH
 9.587
 O
 O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 MET A:102 A:112 83.0 0.449 -97.6 -0.3 83.0 0.449 0.0 HOH
 3.050
 N
 O
MET B:102 B:112 87.0 0.47 -110.8 8.1 87.0 0.47 0.0 HOH
 2.829
 N
 O
MET C:102 C:112 76.0 0.411 -112.8 5.0 76.0 0.411 0.0 HOH
 5.696
 CG
 O
MET D:102 D:112 85.0 0.459 -122.3 3.1 85.0 0.459 0.0 HOH
 8.830
 CE
 O
MET E:102 E:112 83.0 0.449 -111.0 -14.8 83.0 0.449 0.0
MET F:102 F:112 93.0 0.503 -104.8 5.8 93.0 0.503 0.0 HOH
 7.069
 O
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 MET A:102 A:112 85.0 0.459 -99.7 6.2 85.0 0.459 0.0 HOH
 2.593
 O
 O
MET B:102 B:112 96.0 0.519 -108.8 4.3 96.0 0.519 0.0 HOH
 2.886
 O
 O
MET C:102 C:112 79.0 0.427 -105.7 5.6 79.0 0.427 0.0 HOH
 3.092
 C
 O
MET D:102 D:112 84.0 0.454 -104.7 -5.2 84.0 0.454 0.0 HOH
 3.734
 CE
 O
MET E:102 E:112 101.0 0.546 -92.1 -13.6 101.0 0.546 0.0 HOH
 7.874
 CG
 O
MET F:102 F:112 82.0 0.443 -96.7 -12.1 82.0 0.443 0.0 HOH
 3.729
 O
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 MET A:102 A:112 88.0 0.476 -106.8 3.5 88.0 0.476 0.0 HOH
 3.116
 C
 O
MET B:102 B:112 94.0 0.508 -107.9 7.5 94.0 0.508 0.0 HOH
 2.782
 N
 O
MET C:102 C:112 90.0 0.486 -108.3 10.0 90.0 0.486 0.0 HOH
 3.025
 C
 O
MET D:102 D:112 78.0 0.422 -107.5 -6.0 78.0 0.422 0.0 HOH
 3.053
 N
 O
MET E:102 E:112 96.0 0.519 -104.3 -2.0 96.0 0.519 0.0 HOH
 9.834
 CE
 O
MET F:102 F:112 80.0 0.432 -106.3 4.4 80.0 0.432 0.0 HOH
 7.315
 CE
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 MET A:102 A:112 85.0 0.459 -103.2 3.4 85.0 0.459 0.0 HOH
 2.890
 N
 O
MET B:102 B:112 88.0 0.476 -109.2 7.1 88.0 0.476 0.0 HOH
 2.775
 N
 O
MET C:102 C:112 81.0 0.438 -109.6 7.9 81.0 0.438 0.0 HOH
 3.006
 N
 O
MET D:102 D:112 76.0 0.411 -99.6 -12.4 76.0 0.411 0.0 HOH
 2.684
 N
 O
MET E:102 E:112 82.0 0.443 -117.4 -5.3 82.0 0.443 0.0 HOH
 5.440
 CB
 O
MET F:102 F:112 86.0 0.465 -108.5 -6.1 86.0 0.465 0.0 HOH
 6.913
 CG
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 MET A:102 A:112 93.0 0.503 -100.0 -0.5 93.0 0.503 0.0 HOH
 3.031
 N
 O
MET B:102 B:112 93.0 0.503 -102.0 3.8 93.0 0.503 0.0 HOH
 2.727
 O
 O
MET C:102 C:112 72.0 0.389 -108.4 11.5 72.0 0.389 0.0 HOH
 2.860
 N
 O
MET D:102 D:112 82.0 0.443 -104.6 7.7 82.0 0.443 0.0 HOH
 2.773
 N
 O
MET E:102 E:112 87.0 0.47 -104.1 -11.7 87.0 0.47 0.0 HOH
 6.975
 CB
 O
MET F:102 F:112 99.0 0.535 -109.3 6.6 99.0 0.535 0.0
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 MET A:102 A:112 97.0 0.524 -102.3 -16.8 97.0 0.524 0.0 HOH
 3.785
 CG
 O
MET B:102 B:112 102.0 0.551 -104.6 2.2 102.0 0.551 0.0 HOH
 2.965
 N
 O
MET C:102 C:112 90.0 0.486 -113.3 -3.7 90.0 0.486 0.0 HOH
 6.729
 N
 O
MET D:102 D:112 83.0 0.449 -118.1 -26.5 83.0 0.449 0.0 HOH
 3.874
 CE
 O
MET E:102 E:112 85.0 0.459 -117.5 -15.9 85.0 0.459 0.0
MET F:102 F:112 107.0 0.578 -109.9 -4.4 107.0 0.578 0.0 HOH
 6.044
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 MET A:112 A:112 110.0 0.595 -103.0 -2.3