Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11679259 . A C CCDS5985.1:NM_004462.3:c.382Atc>Ctc_NP_004453.3:p.128I>L Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:98 A:128 0.0 0.0 H -67.6 -44.2 0.0 0.0 0.0 HOH
 6.157
 N
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 ILE A:98 A:128 0.0 0.0 H -55.5 -52.1 0.0 0.0 0.0 HOH
 7.155
 O
 O
ILE B:98 B:128 0.0 0.0 H -71.9 -43.7 NA NA NA
ILE C:98 C:128 0.0 0.0 H -55.7 -53.7 NA NA NA
ILE D:98 D:128 0.0 0.0 H -78.2 -14.1 NA NA NA
ILE E:98 E:128 0.0 0.0 H -61.7 -45.6 NA NA NA
ILE F:98 F:128 0.0 0.0 H -95.4 -52.5 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:98 A:128 0.0 0.0 H -71.2 -45.1 0.0 0.0 0.0 HOH
 6.120
 N
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:98 A:128 0.0 0.0 H -74.6 -40.3 0.0 0.0 0.0 HOH
 5.923
 N
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 ILE A:98 A:128 0.0 0.0 H -72.1 -44.9 0.0 0.0 0.0 HOH
 6.046
 N
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:101 A:128 0.0 0.0 H -69.6 -43.2 0.0 0.0 0.0 HOH
 5.823
 N
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:101 A:128 0.0 0.0 H -70.2 -45.6 0.0 0.0 0.0 HOH
 6.160
 N
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:101 A:128 0.0 0.0 H -65.4 -46.6 0.0 0.0 0.0 HOH
 6.237
 N
 O
ILE B:101 B:128 0.0 0.0 H -77.9 -43.4 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:101 A:128 0.0 0.0 H -67.6 -45.9 0.0 0.0 0.0 HOH
 6.113
 N
 O
ILE B:101 B:128 0.0 0.0 H -70.6 -41.1 0.0 0.0 0.0 HOH
 6.043
 N
 O
ILE C:101 C:128 0.0 0.0 H -70.8 -46.4 0.0 0.0 0.0 HOH
 6.099
 N
 O
ILE D:101 D:128 0.0 0.0 H -61.7 -48.1 NA NA NA
ILE E:101 E:128 0.0 0.0 H -63.0 -47.4 NA NA NA
ILE F:101 F:128 0.0 0.0 H -73.1 -36.3 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:101 A:128 0.0 0.0 H -67.8 -46.8 0.0 0.0 0.0 HOH
 6.085
 N
 O
ILE B:101 B:128 0.0 0.0 H -67.6 -44.6 0.0 0.0 0.0 HOH
 6.293
 N
 O
ILE C:101 C:128 0.0 0.0 H -68.4 -45.0 0.0 0.0 0.0 HOH
 6.183
 N
 O
ILE D:101 D:128 0.0 0.0 H -62.1 -47.7 NA NA NA
ILE E:101 E:128 0.0 0.0 H -69.6 -45.7 NA NA NA
ILE F:101 F:128 0.0 0.0 H -60.2 -52.5 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:101 A:128 0.0 0.0 H -72.5 -43.6 0.0 0.0 0.0 HOH
 6.164
 N
 O
ILE B:101 B:128 0.0 0.0 H -69.9 -42.5 0.0 0.0 0.0 HOH
 6.210
 N
 O
ILE C:101 C:128 0.0 0.0 H -66.2 -43.8 0.0 0.0 0.0 HOH
 6.240
 N
 O
ILE D:101 D:128 0.0 0.0 H -63.4 -52.7 NA NA NA
ILE E:101 E:128 0.0 0.0 H -62.8 -53.0 NA NA NA
ILE F:101 F:128 0.0 0.0 H -85.5 -53.1 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:101 A:128 0.0 0.0 H -72.7 -44.2 0.0 0.0 0.0 HOH
 6.127
 N
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:101 A:128 0.0 0.0 H -68.8 -42.4 0.0 0.0 0.0 HOH
 5.945
 N
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:101 A:128 0.0 0.0 H -68.7 -43.3 0.0 0.0 0.0 HOH
 6.071
 N
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:101 A:128 0.0 0.0 H -73.0 -46.0 0.0 0.0 0.0 HOH
 6.116
 N
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:101 A:128 0.0 0.0 H -65.4 -40.0 0.0 0.0 0.0 HOH
 6.275
 N
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 ILE A:98 A:128 0.0 0.0 H -70.8 -40.3 0.0 0.0 0.0 HOH
 6.032
 N
 O
ILE B:98 B:128 0.0 0.0 H -73.4 -48.2 NA NA NA
ILE C:98 C:128 0.0 0.0 H -78.1 -46.3 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:118 A:128 0.0 0.0 H -67.5 -46.8 0.0 0.0 0.0 HOH
 5.891
 C
 O
ILE B:118 B:128 0.0 0.0 H -67.0 -48.4 0.0 0.0 0.0 HOH
 6.767
 O
 O
ILE C:118 C:128 0.0 0.0 H -73.3 -40.7 0.0 0.0 0.0 HOH
 6.434
 C
 O
ILE D:118 D:128 0.0 0.0 H -76.4 -40.0 0.0 0.0 0.0 HOH
 6.869
 O
 O
ILE E:118 E:128 0.0 0.0 H -73.5 -49.5 0.0 0.0 0.0 HOH
 9.605
 O
 O
ILE F:118 F:128 0.0 0.0 H -64.4 -42.4 0.0 0.0 0.0 HOH
 7.270
 N
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:118 A:128 0.0 0.0 H -75.1 -37.2 0.0 0.0 0.0 HOH
 7.593
 N
 O
ILE B:118 B:128 0.0 0.0 H -69.2 -43.9 0.0 0.0 0.0 HOH
 6.335
 N
 O
ILE C:118 C:128 0.0 0.0 H -66.5 -43.0 0.0 0.0 0.0 HOH
 9.225
 CD1
 O
ILE D:118 D:128 0.0 0.0 H -68.9 -48.2 0.0 0.0 0.0 HOH
 7.307
 N
 O
ILE E:118 E:128 0.0 0.0 H -76.6 -36.5 0.0 0.0 0.0 HOH
 6.657
 N
 O
ILE F:118 F:128 0.0 0.0 H -78.7 -47.1 0.0 0.0 0.0 HOH
 7.580
 O
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:118 A:128 0.0 0.0 H -73.3 -47.4 0.0 0.0 0.0 HOH
 5.933
 N
 O
ILE B:118 B:128 0.0 0.0 H -77.8 -43.7 0.0 0.0 0.0 HOH
 6.152
 N
 O
ILE C:118 C:128 0.0 0.0 H -70.2 -43.2 0.0 0.0 0.0 HOH
 6.259
 N
 O
ILE D:118 D:128 0.0 0.0 H -66.3 -44.4 0.0 0.0 0.0 HOH
 6.050
 N
 O
ILE E:118 E:128 0.0 0.0 H -64.1 -54.6 0.0 0.0 0.0
ILE F:118 F:128 0.0 0.0 H -70.8 -53.6 0.0 0.0 0.0 HOH
 7.927
 N
 O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:118 A:128 0.0 0.0 H -68.5 -48.5 0.0 0.0 0.0 HOH
 6.380
 N
 O
ILE B:118 B:128 0.0 0.0 H -75.2 -40.9 0.0 0.0 0.0 HOH
 6.226
 N
 O
ILE C:118 C:128 0.0 0.0 H -59.1 -48.0 0.0 0.0 0.0 HOH
 6.583
 C
 O
ILE D:118 D:128 0.0 0.0 H -68.0 -45.2 0.0 0.0 0.0 HOH
 6.561
 C
 O
ILE E:118 E:128 0.0 0.0 H -66.2 -38.1 0.0 0.0 0.0
ILE F:118 F:128 0.0 0.0 H -73.6 -41.4 0.0 0.0 0.0 HOH
 8.595
 N
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:118 A:128 0.0 0.0 H -69.6 -50.9 0.0 0.0 0.0 HOH
 6.126
 N
 O
ILE B:118 B:128 0.0 0.0 H -70.5 -44.1 0.0 0.0 0.0 HOH
 6.137
 N
 O
ILE C:118 C:128 0.0 0.0 H -66.3 -48.3 0.0 0.0 0.0 HOH
 6.243
 N
 O
ILE D:118 D:128 0.0 0.0 H -67.5 -47.2 0.0 0.0 0.0 HOH
 6.303
 C
 O
ILE E:118 E:128 0.0 0.0 H -81.5 -38.3 0.0 0.0 0.0 HOH
 6.312
 O
 O
ILE F:118 F:128 0.0 0.0 H -70.4 -50.8 0.0 0.0 0.0 HOH
 6.130
 N
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:118 A:128 0.0 0.0 H -72.3 -42.6 0.0 0.0 0.0 HOH
 6.085
 N
 O
ILE B:118 B:128 0.0 0.0 H -69.6 -48.1 0.0 0.0 0.0 HOH
 6.167
 N
 O
ILE C:118 C:128 0.0 0.0 H -70.9 -43.5 0.0 0.0 0.0 HOH
 6.189
 N
 O
ILE D:118 D:128 0.0 0.0 H -73.3 -48.1 0.0 0.0 0.0 HOH
 6.079
 N
 O
ILE E:118 E:128 0.0 0.0 H -69.7 -52.2 0.0 0.0 0.0 HOH
 6.106
 N
 O
ILE F:118 F:128 0.0 0.0 H -78.9 -43.4 0.0 0.0 0.0 HOH
 7.190
 O
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:118 A:128 0.0 0.0 H -71.0 -42.5 0.0 0.0 0.0 HOH
 6.033
 N
 O
ILE B:118 B:128 0.0 0.0 H -72.1 -43.1 0.0 0.0 0.0 HOH
 6.077
 N
 O
ILE C:118 C:128 0.0 0.0 H -70.7 -42.2 0.0 0.0 0.0 HOH
 5.864
 N
 O
ILE D:118 D:128 0.0 0.0 H -70.0 -44.9 0.0 0.0 0.0 HOH
 6.097
 N
 O
ILE E:118 E:128 0.0 0.0 H -71.7 -43.5 0.0 0.0 0.0 HOH
 6.753
 O
 O
ILE F:118 F:128 0.0 0.0 H -70.0 -46.6 0.0 0.0 0.0 HOH
 6.244
 C
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:118 A:128 0.0 0.0 H -72.1 -42.3 0.0 0.0 0.0 HOH
 5.997
 N
 O
ILE B:118 B:128 0.0 0.0 H -71.1 -47.1 0.0 0.0 0.0 HOH
 6.063
 N
 O
ILE C:118 C:128 0.0 0.0 H -70.3 -43.4 0.0 0.0 0.0 HOH
 6.058
 N
 O
ILE D:118 D:128 0.0 0.0 H -75.3 -45.2 0.0 0.0 0.0 HOH
 6.164
 N
 O
ILE E:118 E:128 0.0 0.0 H -64.2 -46.1 0.0 0.0 0.0 HOH
 6.108
 N
 O
ILE F:118 F:128 0.0 0.0 H -76.8 -43.2 0.0 0.0 0.0 HOH
 7.233
 O
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 ILE A:118 A:128 0.0 0.0 H -82.2 -45.3 0.0 0.0 0.0 HOH
 9.818
 N
 O
ILE B:118 B:128 0.0 0.0 H -68.9 -44.8 0.0 0.0 0.0 HOH
 6.961
 N
 O
ILE C:118 C:128 0.0 0.0 H -57.9 -35.0 0.0 0.0 0.0 HOH
 9.621
 N
 O
ILE D:118 D:128 0.0 0.0 H -71.1 -43.7 0.0 0.0 0.0
ILE E:118 E:128 0.0 0.0 H -70.6 -41.7 0.0 0.0 0.0
ILE F:118 F:128 0.0 0.0 H -76.9 -52.8 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 ILE A:128 A:128 0.0 0.0 H -66.7 -46.3