Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11679283 . G A CCDS5985.1:NM_004462.3:c.406Gct>Act_NP_004453.3:p.136A>T Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:106 A:136 42.0 0.365 -55.6 145.1 42.0 0.365 0.0 HOH
 2.946
 N
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 ALA A:106 A:136 37.0 0.322 -65.0 147.5 37.0 0.322 0.0 HOH
 5.967
 N
 O
ALA B:106 B:136 32.0 0.278 -42.2 130.1 NA NA NA
ALA C:106 C:136 44.0 0.383 -52.0 144.5 NA NA NA
ALA D:106 D:136 42.0 0.365 -52.8 153.5 NA NA NA
ALA E:106 E:136 38.0 0.33 -77.2 166.5 NA NA NA
ALA F:106 F:136 34.0 0.296 -55.1 163.0 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:106 A:136 37.0 0.322 -53.9 149.9 37.0 0.322 0.0 HOH
 3.119
 N
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:106 A:136 43.0 0.374 -54.6 147.1 43.0 0.374 0.0 HOH
 2.993
 N
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 ALA A:106 A:136 43.0 0.374 -54.3 145.6 43.0 0.374 0.0 HOH
 2.881
 N
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:109 A:136 44.0 0.383 -57.7 150.2 44.0 0.383 0.0 HOH
 2.895
 N
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:109 A:136 44.0 0.383 -54.7 146.7 44.0 0.383 0.0 HOH
 2.933
 N
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:109 A:136 46.0 0.4 -56.5 145.8 46.0 0.4 0.0 HOH
 2.943
 N
 O
ALA B:109 B:136 39.0 0.339 -57.2 149.2 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:109 A:136 40.0 0.348 -57.1 146.6 40.0 0.348 0.0 HOH
 2.712
 N
 O
ALA B:109 B:136 44.0 0.383 -43.5 140.8 44.0 0.383 0.0 HOH
 3.054
 N
 O
ALA C:109 C:136 37.0 0.322 -57.0 146.9 37.0 0.322 0.0 HOH
 2.966
 N
 O
ALA D:109 D:136 44.0 0.383 -54.5 143.4 NA NA NA
ALA E:109 E:136 48.0 0.417 -52.9 145.4 NA NA NA
ALA F:109 F:136 41.0 0.357 -57.1 155.3 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:109 A:136 43.0 0.374 -56.6 145.8 43.0 0.374 0.0 HOH
 2.932
 N
 O
ALA B:109 B:136 43.0 0.374 -50.3 143.7 43.0 0.374 0.0 HOH
 2.931
 N
 O
ALA C:109 C:136 49.0 0.426 -55.7 144.0 49.0 0.426 0.0 HOH
 2.906
 N
 O
ALA D:109 D:136 38.0 0.33 -55.0 143.2 NA NA NA
ALA E:109 E:136 40.0 0.348 -51.3 145.4 NA NA NA
ALA F:109 F:136 43.0 0.374 -55.8 141.1 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:109 A:136 44.0 0.383 -55.5 138.7 44.0 0.383 0.0 HOH
 2.848
 N
 O
ALA B:109 B:136 37.0 0.322 -42.1 132.7 37.0 0.322 0.0 HOH
 3.698
 CB
 O
ALA C:109 C:136 36.0 0.313 -50.1 147.8 36.0 0.313 0.0 HOH
 2.988
 N
 O
ALA D:109 D:136 33.0 0.287 -63.5 144.3 NA NA NA
ALA E:109 E:136 37.0 0.322 -59.0 144.0 NA NA NA
ALA F:109 F:136 43.0 0.374 -65.7 150.2 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:109 A:136 45.0 0.391 -55.4 145.4 45.0 0.391 0.0 HOH
 2.959
 N
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:109 A:136 44.0 0.383 -57.3 149.6 44.0 0.383 0.0 HOH
 2.972
 N
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:109 A:136 48.0 0.417 -54.3 147.8 48.0 0.417 0.0 HOH
 3.151
 N
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:109 A:136 37.0 0.322 -54.4 144.9 37.0 0.322 0.0 HOH
 2.915
 N
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:109 A:136 48.0 0.417 -52.7 144.2 48.0 0.417 0.0 HOH
 2.922
 N
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 ALA A:106 A:136 30.0 0.261 -61.6 139.4 30.0 0.261 0.0 HOH
 2.805
 N
 O
ALA B:106 B:136 37.0 0.322 -62.0 142.4 NA NA NA
ALA C:106 C:136 45.0 0.391 -60.0 146.7 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:126 A:136 39.0 0.339 -55.1 158.1 39.0 0.339 0.0 HOH
 2.982
 N
 O
ALA B:126 B:136 38.0 0.33 -77.3 151.2 30.0 0.261 0.069 D:P37268:0.07
 HOH
 3.052
 N
 O
ALA C:126 C:136 37.0 0.322 -55.2 135.7 37.0 0.322 0.0 HOH
 5.960
 CA
 O
ALA D:126 D:136 41.0 0.357 -50.6 153.4 32.0 0.278 0.079 B:P37268:0.078
 HOH
 3.710
 N
 O
ALA E:126 E:136 44.0 0.383 -48.2 120.2 44.0 0.383 0.0 HOH
 3.359
 CB
 O
ALA F:126 F:136 36.0 0.313 -58.5 155.2 36.0 0.313 0.0 HOH
 2.545
 N
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:126 A:136 37.0 0.322 -60.7 150.3 36.0 0.313 0.009 E:P37268:0.009
 HOH
 3.995
 CB
 O
ALA B:126 B:136 39.0 0.339 -64.7 141.2 31.0 0.27 0.069 D:P37268:0.07
 HOH
 3.767
 CB
 O
ALA C:126 C:136 40.0 0.348 -70.6 136.9 40.0 0.348 0.0 HOH
 3.749
 C
 O
ALA D:126 D:136 44.0 0.383 -65.0 139.5 34.0 0.296 0.087 B:P37268:0.087
 HOH
 3.590
 CB
 O
ALA E:126 E:136 32.0 0.278 -61.1 157.8 30.0 0.261 0.017 A:P37268:0.017
 HOH
 4.059
 CA
 O
ALA F:126 F:136 36.0 0.313 -51.7 151.6 36.0 0.313 0.0 HOH
 5.916
 C
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:126 A:136 38.0 0.33 -52.5 149.6 37.0 0.322 0.008 E:P37268:0.009
 HOH
 2.662
 N
 O
ALA B:126 B:136 36.0 0.313 -55.6 151.1 27.0 0.235 0.078 D:P37268:0.078
 HOH
 2.830
 N
 O
ALA C:126 C:136 41.0 0.357 -56.2 142.5 41.0 0.357 0.0 HOH
 2.886
 N
 O
ALA D:126 D:136 37.0 0.322 -60.4 146.2 28.0 0.243 0.079 B:P37268:0.078
 HOH
 3.025
 N
 O
ALA E:126 E:136 41.0 0.357 -59.0 136.8 41.0 0.357 0.0 HOH
 3.615
 CB
 O
ALA F:126 F:136 40.0 0.348 -52.7 146.7 40.0 0.348 0.0 HOH
 9.878
 CB
 O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:126 A:136 37.0 0.322 -58.3 148.5 26.0 0.226 0.096 E:P37268:0.096
 HOH
 2.933
 N
 O
ALA B:126 B:136 41.0 0.357 -60.3 145.1 32.0 0.278 0.079 D:P37268:0.078
 HOH
 2.902
 N
 O
ALA C:126 C:136 39.0 0.339 -60.4 146.2 39.0 0.339 0.0 HOH
 3.094
 N
 O
ALA D:126 D:136 40.0 0.348 -59.7 150.5 30.0 0.261 0.087 B:P37268:0.087
 HOH
 3.357
 CA
 O
ALA E:126 E:136 43.0 0.374 -54.8 146.4 14.0 0.122 0.252 A:P37268:0.252
 HOH
 3.948
 CB
 O
ALA F:126 F:136 38.0 0.33 -52.3 146.8 36.0 0.313 0.017 C:P37268:0.017
 HOH
 4.930
 N
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:126 A:136 46.0 0.4 -64.8 147.8 45.0 0.391 0.009 E:P37268:0.009
 HOH
 2.786
 N
 O
ALA B:126 B:136 45.0 0.391 -55.9 145.2 35.0 0.304 0.087 D:P37268:0.087
 HOH
 2.914
 N
 O
ALA C:126 C:136 45.0 0.391 -52.3 143.9 45.0 0.391 0.0 HOH
 3.041
 N
 O
ALA D:126 D:136 34.0 0.296 -57.9 143.4 26.0 0.226 0.07 B:P37268:0.07
 HOH
 2.846
 N
 O
ALA E:126 E:136 40.0 0.348 -56.5 157.0 33.0 0.287 0.061 A:P37268:0.061
 HOH
 3.315
 N
 O
ALA F:126 F:136 39.0 0.339 -57.7 150.7 39.0 0.339 0.0 HOH
 3.957
 C
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:126 A:136 39.0 0.339 -59.1 146.6 39.0 0.339 0.0 HOH
 2.613
 N
 O
ALA B:126 B:136 38.0 0.33 -59.2 148.2 30.0 0.261 0.069 D:P37268:0.07
 HOH
 2.883
 N
 O
ALA C:126 C:136 45.0 0.391 -56.7 142.4 45.0 0.391 0.0 HOH
 3.036
 N
 O
ALA D:126 D:136 35.0 0.304 -56.6 145.8 27.0 0.235 0.069 B:P37268:0.07
 HOH
 2.759
 N
 O
ALA E:126 E:136 35.0 0.304 -59.2 141.3 35.0 0.304 0.0 HOH
 3.420
 CA
 O
ALA F:126 F:136 37.0 0.322 -67.8 155.4 37.0 0.322 0.0 HOH
 5.401
 N
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:126 A:136 36.0 0.313 -59.4 142.9 32.0 0.278 0.035 E:P37268:0.035
 HOH
 2.728
 N
 O
ALA B:126 B:136 39.0 0.339 -56.3 147.6 29.0 0.252 0.087 D:P37268:0.087
 HOH
 3.053
 N
 O
ALA C:126 C:136 41.0 0.357 -53.2 142.5 41.0 0.357 0.0 HOH
 2.890
 N
 O
ALA D:126 D:136 34.0 0.296 -59.5 146.0 26.0 0.226 0.07 B:P37268:0.07
 HOH
 2.941
 N
 O
ALA E:126 E:136 44.0 0.383 -74.3 153.5 41.0 0.357 0.026 A:P37268:0.026
 HOH
 6.388
 CB
 O
ALA F:126 F:136 42.0 0.365 -55.7 153.2 42.0 0.365 0.0 HOH
 2.742
 N
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:126 A:136 39.0 0.339 -61.4 150.1 39.0 0.339 0.0 HOH
 2.853
 N
 O
ALA B:126 B:136 37.0 0.322 -59.8 143.2 28.0 0.243 0.079 D:P37268:0.078
 HOH
 2.967
 N
 O
ALA C:126 C:136 43.0 0.374 -55.8 144.9 43.0 0.374 0.0 HOH
 2.988
 N
 O
ALA D:126 D:136 35.0 0.304 -59.2 146.8 26.0 0.226 0.078 B:P37268:0.078
 HOH
 2.847
 N
 O
ALA E:126 E:136 39.0 0.339 -62.3 137.4 39.0 0.339 0.0 HOH
 2.850
 N
 O
ALA F:126 F:136 41.0 0.357 -61.6 154.5 41.0 0.357 0.0 HOH
 2.882
 N
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 ALA A:126 A:136 32.0 0.278 -59.0 150.0 31.0 0.27 0.008 E:P37268:0.009
 HOH
 3.872
 CA
 O
ALA B:126 B:136 35.0 0.304 -58.0 143.9 29.0 0.252 0.052 D:P37268:0.052
 HOH
 7.717
 C
 O
ALA C:126 C:136 36.0 0.313 -63.5 141.8 36.0 0.313 0.0 HOH
 5.534
 N
 O
ALA D:126 D:136 36.0 0.313 -54.2 141.1 27.0 0.235 0.078 B:P37268:0.078
 HOH
 7.057
 C
 O
ALA E:126 E:136 45.0 0.391 -58.5 145.2 33.0 0.287 0.104 A:P37268:0.104
 HOH
 5.241
 CB
 O
ALA F:126 F:136 37.0 0.322 -51.8 153.3 37.0 0.322 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 ALA A:136 A:136 46.0 0.4 -58.5 145.8