Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11679319 . C A CCDS5985.1:NM_004462.3:c.442Cgg>Agg_NP_004453.3:p.148R>R Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ARG A:118 A:148 94.0 0.418 H -57.7 -48.7 94.0 0.418 0.0 PO4
HOH
 5.652
2.563
 NH1
NE
 O1
O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 ARG A:118 A:148 98.0 0.436 H -66.1 -31.2 98.0 0.436 0.0 HOH
 3.334
 CA
 O
ARG B:118 B:148 99.0 0.44 H -77.7 -41.1 NA NA NA
ARG C:118 C:148 95.0 0.422 H -67.9 -56.8 NA NA NA
ARG D:118 D:148 99.0 0.44 H -72.1 -50.5 NA NA NA
ARG E:118 E:148 98.0 0.436 H -58.8 -45.9 NA NA NA
ARG F:118 F:148 87.0 0.387 H -65.2 -59.3 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ARG A:118 A:148 98.0 0.436 H -59.0 -46.5 98.0 0.436 0.0 PO4
HOH
 5.681
2.680
 NH1
NE
 O1
O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ARG A:118 A:148 100.0 0.444 H -60.0 -48.7 100.0 0.444 0.0 PO4
HOH
 5.596
2.594
 NH1
NH1
 O1
O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 ARG A:118 A:148 98.0 0.436 H -64.8 -46.5 98.0 0.436 0.0 PO4
HOH
 5.655
2.576
 NH1
NH2
 O1
O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ARG A:121 A:148 92.0 0.409 H -59.6 -48.8 92.0 0.409 0.0 HOH
 2.863
 O
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ARG A:121 A:148 102.0 0.453 H -59.5 -51.8 102.0 0.453 0.0 HOH
 2.783
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ARG A:121 A:148 102.0 0.453 H -58.1 -51.6 102.0 0.453 0.0 NI
HOH
 9.695
2.323
 O
NH1
 NI
O
ARG B:121 B:148 84.0 0.373 H -62.1 -50.9 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ARG A:121 A:148 100.0 0.444 H -58.7 -47.4 100.0 0.444 0.0 HOH
 2.771
 NH1
 O
ARG B:121 B:148 95.0 0.422 H -60.6 -51.4 95.0 0.422 0.0 HOH
 2.930
 NH1
 O
ARG C:121 C:148 95.0 0.422 H -62.0 -50.5 95.0 0.422 0.0 HOH
 2.843
 O
 O
ARG D:121 D:148 89.0 0.396 H -67.1 -53.4 NA NA NA
ARG E:121 E:148 102.0 0.453 H -57.5 -52.8 NA NA NA
ARG F:121 F:148 107.0 0.476 H -63.9 -52.2 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ARG A:121 A:148 103.0 0.458 H -57.1 -51.7 103.0 0.458 0.0 PO4
HOH
 5.752
2.562
 NH1
NE
 O2
O
ARG B:121 B:148 97.0 0.431 H -63.5 -49.6 97.0 0.431 0.0 PO4
HOH
 5.813
2.711
 NH1
NH2
 O2
O
ARG C:121 C:148 95.0 0.422 H -64.9 -46.1 95.0 0.422 0.0 PO4
HOH
 5.853
2.743
 NH1
NE
 O2
O
ARG D:121 D:148 96.0 0.427 H -61.0 -54.5 NA NA NA
ARG E:121 E:148 98.0 0.436 H -58.0 -51.1 NA NA NA
ARG F:121 F:148 88.0 0.391 H -70.0 -58.4 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ARG A:121 A:148 101.0 0.449 H -53.7 -55.4 101.0 0.449 0.0 HOH
 2.854
 NE
 O
ARG B:121 B:148 98.0 0.436 H -60.1 -49.3 98.0 0.436 0.0 HOH
 2.996
 NH1
 O
ARG C:121 C:148 96.0 0.427 H -62.5 -52.7 96.0 0.427 0.0 HOH
 2.662
 NH2
 O
ARG D:121 D:148 95.0 0.422 H -46.3 -63.7 NA NA NA
ARG E:121 E:148 102.0 0.453 H -68.8 -44.7 NA NA NA
ARG F:121 F:148 97.0 0.431 H -70.8 -55.3 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ARG A:121 A:148 89.0 0.396 H -57.9 -49.8 89.0 0.396 0.0 HOH
 2.903
 O
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ARG A:121 A:148 93.0 0.413 H -62.5 -48.7 93.0 0.413 0.0 HOH
 2.409
 NH1
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ARG A:121 A:148 90.0 0.4 H -60.6 -47.9 90.0 0.4 0.0 HOH
 3.399
 CA
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ARG A:121 A:148 94.0 0.418 H -60.9 -49.6 94.0 0.418 0.0 HOH
 2.821
 O
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ARG A:121 A:148 109.0 0.484 H -62.4 -47.4 109.0 0.484 0.0 HOH
 2.941
 O
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 ARG A:118 A:148 94.0 0.418 H -65.7 -53.0 94.0 0.418 0.0 HOH
 2.794
 O
 O
ARG B:118 B:148 88.0 0.391 H -64.7 -48.4 NA NA NA
ARG C:118 C:148 105.0 0.467 H -65.8 -56.7 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ARG A:138 A:148 103.0 0.458 H -66.2 -51.3 103.0 0.458 0.0 HOH
 3.672
 NH1
 O
ARG B:138 B:148 88.0 0.391 H -65.7 -46.7 88.0 0.391 0.0 HOH
 3.428
 NH2
 O
ARG C:138 C:148 97.0 0.431 H -59.8 -51.7 97.0 0.431 0.0 HOH
 3.390
 CG
 O
ARG D:138 D:148 96.0 0.427 H -78.5 -41.5 96.0 0.427 0.0 HOH
 7.345
 O
 O
ARG E:138 E:148 97.0 0.431 H -70.9 -65.0 97.0 0.431 0.0
ARG F:138 F:148 99.0 0.44 H -47.1 -59.1 99.0 0.44 0.0 HOH
 7.527
 NH1
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ARG A:138 A:148 94.0 0.418 H -52.5 -50.8 94.0 0.418 0.0 HOH
 3.533
 NE
 O
ARG B:138 B:148 97.0 0.431 H -62.4 -65.2 97.0 0.431 0.0 HOH
 2.634
 NH1
 O
ARG C:138 C:148 98.0 0.436 H -68.4 -37.8 98.0 0.436 0.0 HOH
 3.046
 NH2
 O
ARG D:138 D:148 104.0 0.462 H -63.7 -51.1 104.0 0.462 0.0 HOH
 2.996
 NE
 O
ARG E:138 E:148 96.0 0.427 H -73.1 -56.6 96.0 0.427 0.0 HOH
 3.783
 NE
 O
ARG F:138 F:148 94.0 0.418 H -60.7 -61.2 94.0 0.418 0.0 HOH
 3.460
 NH1
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ARG A:138 A:148 102.0 0.453 H -59.9 -51.2 102.0 0.453 0.0 HOH
 2.770
 NH2
 O
ARG B:138 B:148 94.0 0.418 H -61.2 -56.1 94.0 0.418 0.0 HOH
 2.858
 O
 O
ARG C:138 C:148 97.0 0.431 H -60.7 -54.8 97.0 0.431 0.0 HOH
 3.216
 NH1
 O
ARG D:138 D:148 100.0 0.444 H -68.9 -46.7 100.0 0.444 0.0 HOH
 3.557
 CA
 O
ARG E:138 E:148 91.0 0.404 H -72.0 -55.5 91.0 0.404 0.0 HOH
 8.062
 NH1
 O
ARG F:138 F:148 86.0 0.382 H -55.8 -61.6 86.0 0.382 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ARG A:138 A:148 99.0 0.44 H -63.1 -44.4 99.0 0.44 0.0 HOH
 2.780
 O
 O
ARG B:138 B:148 92.0 0.409 H -59.1 -53.4 92.0 0.409 0.0 HOH
 3.580
 CA
 O
ARG C:138 C:148 96.0 0.427 H -53.5 -60.9 96.0 0.427 0.0 HOH
 2.809
 NE
 O
ARG D:138 D:148 100.0 0.444 H -57.6 -52.9 100.0 0.444 0.0 HOH
 3.528
 CA
 O
ARG E:138 E:148 95.0 0.422 H -76.2 -49.4 95.0 0.422 0.0 HOH
 3.976
 CA
 O
ARG F:138 F:148 101.0 0.449 H -63.7 -54.6 101.0 0.449 0.0 HOH
 3.498
 CA
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ARG A:138 A:148 99.0 0.44 H -60.4 -53.6 99.0 0.44 0.0 HOH
 3.429
 NH1
 O
ARG B:138 B:148 92.0 0.409 H -63.0 -51.0 92.0 0.409 0.0 HOH
 2.744
 O
 O
ARG C:138 C:148 93.0 0.413 H -60.7 -56.1 93.0 0.413 0.0 HOH
 2.761
 NH2
 O
ARG D:138 D:148 107.0 0.476 H -63.6 -50.3 107.0 0.476 0.0 HOH
 2.932
 NE
 O
ARG E:138 E:148 106.0 0.471 H -77.3 -48.6 106.0 0.471 0.0 HOH
 2.656
 NH2
 O
ARG F:138 F:148 96.0 0.427 H -64.6 -56.9 96.0 0.427 0.0 HOH
 2.737
 NH2
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ARG A:138 A:148 97.0 0.431 H -56.9 -55.6 97.0 0.431 0.0 HOH
 2.552
 NH2
 O
ARG B:138 B:148 96.0 0.427 H -67.0 -54.1 96.0 0.427 0.0 HOH
 2.750
 O
 O
ARG C:138 C:148 95.0 0.422 H -64.0 -50.9 95.0 0.422 0.0 HOH
 3.146
 NE
 O
ARG D:138 D:148 97.0 0.431 H -62.9 -47.8 97.0 0.431 0.0 HOH
 3.327
 NH2
 O
ARG E:138 E:148 96.0 0.427 H -68.8 -58.5 96.0 0.427 0.0 HOH
 8.890
 NH1
 O
ARG F:138 F:148 98.0 0.436 H -58.0 -55.7 98.0 0.436 0.0 HOH
 4.652
 NH1
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ARG A:138 A:148 101.0 0.449 H -58.1 -56.7 101.0 0.449 0.0 HOH
 2.554
 NH2
 O
ARG B:138 B:148 100.0 0.444 H -62.4 -56.3 100.0 0.444 0.0 HOH
 2.868
 NH2
 O
ARG C:138 C:148 95.0 0.422 H -59.2 -57.5 95.0 0.422 0.0 HOH
 3.058
 NH2
 O
ARG D:138 D:148 106.0 0.471 H -64.3 -50.9 106.0 0.471 0.0 HOH
 3.632
 CA
 O
ARG E:138 E:148 99.0 0.44 H -65.7 -58.9 99.0 0.44 0.0 HOH
 2.707
 NH2
 O
ARG F:138 F:148 97.0 0.431 H -56.6 -58.9 97.0 0.431 0.0 HOH
 3.287
 CA
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ARG A:138 A:148 97.0 0.431 H -60.7 -49.9 97.0 0.431 0.0 HOH
 2.511
 NH2
 O
ARG B:138 B:148 94.0 0.418 H -61.9 -51.7 94.0 0.418 0.0 HOH
 2.759
 O
 O
ARG C:138 C:148 97.0 0.431 H -63.7 -48.1 97.0 0.431 0.0 HOH
 2.864
 O
 O
ARG D:138 D:148 98.0 0.436 H -64.3 -46.3 98.0 0.436 0.0 HOH
 2.654
 NE
 O
ARG E:138 E:148 97.0 0.431 H -61.9 -58.2 97.0 0.431 0.0 HOH
 3.125
 O
 O
ARG F:138 F:148 95.0 0.422 H -60.5 -54.2 95.0 0.422 0.0 HOH
 8.307
 NH1
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 ARG A:138 A:148 99.0 0.44 H -61.2 -44.9 99.0 0.44 0.0 HOH
 8.694
 NH1
 O
ARG B:138 B:148 92.0 0.409 H -70.1 -60.1 92.0 0.409 0.0 HOH
 5.579
 NH1
 O
ARG C:138 C:148 96.0 0.427 H -63.2 -56.4 96.0 0.427 0.0 HOH
 7.841
 NH1
 O
ARG D:138 D:148 102.0 0.453 H -80.0 -48.2 102.0 0.453 0.0
ARG E:138 E:148 105.0 0.467 H -76.9 -54.4 105.0 0.467 0.0 HOH
 5.818
 NH2
 O
ARG F:138 F:148 98.0 0.436 H -66.2 -63.0 98.0 0.436 0.0 HOH
 8.854
 NH1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 ARG A:148 A:148 92.0 0.409 H -63.0 -50.2