Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11679331 . A C CCDS5985.1:NM_004462.3:c.454Att>Ctt_NP_004453.3:p.152I>L Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:122 A:152 76.0 0.434 H -58.4 -50.0 76.0 0.434 0.0 PO4
HOH
 6.419
2.828
 CD1
O
 O1
O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 ILE A:122 A:152 78.0 0.446 H -66.4 -6.3 78.0 0.446 0.0 HOH
 5.219
 N
 O
ILE B:122 B:152 69.0 0.394 H -64.7 -38.1 NA NA NA
ILE C:122 C:152 67.0 0.383 H -48.8 -34.9 NA NA NA
ILE D:122 D:152 77.0 0.44 H -51.0 -55.0 NA NA NA
ILE E:122 E:152 69.0 0.394 H -65.2 -51.6 NA NA NA
ILE F:122 F:152 84.0 0.48 H -38.4 -52.6 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:122 A:152 81.0 0.463 H -55.4 -47.5 81.0 0.463 0.0 PO4
HOH
 6.584
2.958
 CG2
O
 O4
O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:122 A:152 74.0 0.423 H -64.3 -44.1 74.0 0.423 0.0 PO4
HOH
 6.376
2.721
 CG2
O
 O4
O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 ILE A:122 A:152 75.0 0.429 H -56.5 -49.3 75.0 0.429 0.0 PO4
HOH
 6.319
2.775
 CG2
O
 O4
O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:125 A:152 73.0 0.417 H -59.3 -46.1 73.0 0.417 0.0 HOH
 2.766
 O
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:125 A:152 70.0 0.4 H -64.0 -43.8 70.0 0.4 0.0 HOH
 2.808
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:125 A:152 73.0 0.417 H -64.3 -45.4 73.0 0.417 0.0 NI
HOH
 7.212
2.714
 CG1
O
 NI
O
ILE B:125 B:152 68.0 0.389 H -65.7 -42.4 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:125 A:152 78.0 0.446 H -63.3 -45.4 78.0 0.446 0.0 HOH
 2.638
 O
 O
ILE B:125 B:152 69.0 0.394 H -55.7 -52.2 69.0 0.394 0.0 HOH
 2.707
 O
 O
ILE C:125 C:152 65.0 0.371 H -56.8 -46.9 65.0 0.371 0.0 HOH
 2.619
 O
 O
ILE D:125 D:152 71.0 0.406 H -68.6 -50.5 NA NA NA
ILE E:125 E:152 70.0 0.4 H -57.2 -50.1 NA NA NA
ILE F:125 F:152 84.0 0.48 H -61.9 -51.1 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:125 A:152 79.0 0.451 H -63.0 -45.8 79.0 0.451 0.0 PO4
HOH
 6.641
2.751
 CG2
O
 O1
O
ILE B:125 B:152 66.0 0.377 H -55.7 -47.7 66.0 0.377 0.0 PO4
HOH
 6.430
2.663
 CG2
O
 O1
O
ILE C:125 C:152 66.0 0.377 H -58.4 -48.4 66.0 0.377 0.0 PO4
HOH
 6.539
2.742
 CG2
O
 O1
O
ILE D:125 D:152 75.0 0.429 H -62.3 -43.5 NA NA NA
ILE E:125 E:152 63.0 0.36 H -61.2 -50.9 NA NA NA
ILE F:125 F:152 75.0 0.429 H -53.3 -35.4 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:125 A:152 76.0 0.434 H -59.2 -48.8 76.0 0.434 0.0 HOH
 2.593
 O
 O
ILE B:125 B:152 62.0 0.354 H -59.5 -44.9 62.0 0.354 0.0 HOH
 3.556
 CD1
 O
ILE C:125 C:152 63.0 0.36 H -49.2 -55.9 63.0 0.36 0.0 HOH
 3.541
 CG1
 O
ILE D:125 D:152 61.0 0.349 H -54.7 -52.1 NA NA NA
ILE E:125 E:152 63.0 0.36 H -65.4 -40.6 NA NA NA
ILE F:125 F:152 81.0 0.463 H -41.9 -50.0 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:125 A:152 77.0 0.44 H -59.3 -42.5 77.0 0.44 0.0 HOH
 2.687
 O
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:125 A:152 69.0 0.394 H -61.5 -46.1 69.0 0.394 0.0 HOH
 2.734
 O
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:125 A:152 72.0 0.411 H -59.5 -40.1 72.0 0.411 0.0 HOH
 3.455
 CG2
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:125 A:152 81.0 0.463 H -60.3 -42.8 81.0 0.463 0.0 HOH
 2.585
 O
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:125 A:152 72.0 0.411 H -61.3 -46.1 72.0 0.411 0.0 HOH
 2.649
 O
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 ILE A:122 A:152 74.0 0.423 H -52.3 -46.5 74.0 0.423 0.0 HOH
 2.833
 O
 O
ILE B:122 B:152 68.0 0.389 H -55.4 -51.3 NA NA NA
ILE C:122 C:152 75.0 0.429 H -58.1 -53.4 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:142 A:152 83.0 0.474 H -49.8 -42.3 83.0 0.474 0.0 HOH
 6.673
 CD1
 O
ILE B:142 B:152 62.0 0.354 H -52.1 -46.2 62.0 0.354 0.0 HOH
 3.372
 CG1
 O
ILE C:142 C:152 70.0 0.4 H -46.3 -52.5 70.0 0.4 0.0 HOH
 3.872
 CD1
 O
ILE D:142 D:152 65.0 0.371 H -56.8 -43.9 65.0 0.371 0.0 HOH
 2.775
 O
 O
ILE E:142 E:152 64.0 0.366 H -75.4 -49.8 64.0 0.366 0.0 HOH
 9.584
 CG2
 O
ILE F:142 F:152 55.0 0.314 H -38.3 -51.4 55.0 0.314 0.0 HOH
 7.277
 CG2
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:142 A:152 80.0 0.457 H -63.5 -39.4 80.0 0.457 0.0 HOH
 7.596
 CG2
 O
ILE B:142 B:152 64.0 0.366 H -54.7 -49.7 64.0 0.366 0.0 HOH
 4.702
 O
 O
ILE C:142 C:152 67.0 0.383 H -54.3 -56.7 67.0 0.383 0.0 HOH
 4.468
 CG1
 O
ILE D:142 D:152 65.0 0.371 H -77.7 -45.1 65.0 0.371 0.0 HOH
 4.520
 CG2
 O
ILE E:142 E:152 68.0 0.389 H -60.4 -43.6 68.0 0.389 0.0 HOH
 6.578
 CB
 O
ILE F:142 F:152 68.0 0.389 H -48.9 -39.6 68.0 0.389 0.0 HOH
 3.289
 CD1
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:142 A:152 79.0 0.451 H -61.9 -42.9 79.0 0.451 0.0 HOH
 2.654
 O
 O
ILE B:142 B:152 70.0 0.4 H -60.0 -49.3 70.0 0.4 0.0 HOH
 2.601
 O
 O
ILE C:142 C:152 68.0 0.389 H -58.0 -45.6 68.0 0.389 0.0 HOH
 3.808
 CD1
 O
ILE D:142 D:152 68.0 0.389 H -57.6 -46.1 68.0 0.389 0.0 HOH
 3.634
 CD1
 O
ILE E:142 E:152 71.0 0.406 H -60.6 -62.0 71.0 0.406 0.0 HOH
 8.199
 CG2
 O
ILE F:142 F:152 65.0 0.371 H -53.1 -48.5 65.0 0.371 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:142 A:152 78.0 0.446 H -58.2 -47.9 78.0 0.446 0.0 HOH
 3.446
 CG1
 O
ILE B:142 B:152 64.0 0.366 H -55.9 -56.4 64.0 0.366 0.0 HOH
 3.090
 O
 O
ILE C:142 C:152 65.0 0.371 H -57.7 -49.3 65.0 0.371 0.0 HOH
 7.086
 CD1
 O
ILE D:142 D:152 64.0 0.366 H -64.8 -53.3 64.0 0.366 0.0 HOH
 5.472
 N
 O
ILE E:142 E:152 63.0 0.36 H -61.7 -48.6 63.0 0.36 0.0 HOH
 5.423
 N
 O
ILE F:142 F:152 69.0 0.394 H -52.3 -59.6 69.0 0.394 0.0 HOH
 5.376
 N
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:142 A:152 77.0 0.44 H -61.3 -46.4 77.0 0.44 0.0 HOH
 2.703
 O
 O
ILE B:142 B:152 66.0 0.377 H -61.0 -46.1 66.0 0.377 0.0 HOH
 2.767
 O
 O
ILE C:142 C:152 72.0 0.411 H -61.5 -47.4 72.0 0.411 0.0 HOH
 2.713
 O
 O
ILE D:142 D:152 62.0 0.354 H -67.3 -59.0 62.0 0.354 0.0 HOH
 3.037
 O
 O
ILE E:142 E:152 66.0 0.377 H -63.1 -55.9 66.0 0.377 0.0 HOH
 2.770
 O
 O
ILE F:142 F:152 69.0 0.394 H -58.8 -60.5 69.0 0.394 0.0 HOH
 3.343
 CD1
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:142 A:152 79.0 0.451 H -63.0 -42.1 79.0 0.451 0.0 HOH
 2.549
 O
 O
ILE B:142 B:152 71.0 0.406 H -59.5 -50.8 71.0 0.406 0.0 HOH
 2.864
 O
 O
ILE C:142 C:152 71.0 0.406 H -60.9 -42.6 71.0 0.406 0.0 HOH
 3.729
 CG2
 O
ILE D:142 D:152 69.0 0.394 H -57.1 -52.2 69.0 0.394 0.0 HOH
 3.109
 O
 O
ILE E:142 E:152 61.0 0.349 H -72.4 -52.7 61.0 0.349 0.0
ILE F:142 F:152 85.0 0.486 H -48.4 -52.1 85.0 0.486 0.0 HOH
 7.603
 CD1
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:142 A:152 82.0 0.469 H -61.3 -44.2 82.0 0.469 0.0 HOH
 2.701
 O
 O
ILE B:142 B:152 72.0 0.411 H -55.8 -52.1 72.0 0.411 0.0 HOH
 2.876
 O
 O
ILE C:142 C:152 70.0 0.4 H -60.7 -40.2 70.0 0.4 0.0 HOH
 2.669
 O
 O
ILE D:142 D:152 67.0 0.383 H -55.4 -52.1 67.0 0.383 0.0 HOH
 2.737
 O
 O
ILE E:142 E:152 69.0 0.394 H -60.8 -49.3 69.0 0.394 0.0 HOH
 3.551
 CD1
 O
ILE F:142 F:152 70.0 0.4 H -52.7 -59.5 70.0 0.4 0.0 HOH
 5.091
 N
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:142 A:152 78.0 0.446 H -64.1 -44.7 78.0 0.446 0.0 HOH
 2.734
 O
 O
ILE B:142 B:152 75.0 0.429 H -60.8 -49.0 75.0 0.429 0.0 HOH
 2.740
 O
 O
ILE C:142 C:152 74.0 0.423 H -59.1 -46.9 74.0 0.423 0.0 HOH
 2.871
 O
 O
ILE D:142 D:152 70.0 0.4 H -62.4 -51.7 70.0 0.4 0.0 HOH
 3.047
 O
 O
ILE E:142 E:152 68.0 0.389 H -63.0 -50.1 68.0 0.389 0.0 HOH
 2.769
 O
 O
ILE F:142 F:152 75.0 0.429 H -56.9 -52.5 75.0 0.429 0.0
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 ILE A:142 A:152 83.0 0.474 H -57.9 -39.0 83.0 0.474 0.0
ILE B:142 B:152 65.0 0.371 H -59.3 -47.5 65.0 0.371 0.0 HOH
 4.732
 CG1
 O
ILE C:142 C:152 76.0 0.434 H -60.7 -41.2 76.0 0.434 0.0 HOH
 7.689
 CG2
 O
ILE D:142 D:152 63.0 0.36 H -69.1 -45.7 63.0 0.36 0.0 HOH
 6.392
 CG2
 O
ILE E:142 E:152 68.0 0.389 H -86.2 -50.6 68.0 0.389 0.0 HOH
 5.804
 CD1
 O
ILE F:142 F:152 71.0 0.406 H -54.3 -70.9 71.0 0.406 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 ILE A:152 A:152 71.0 0.406 H -62.9 -44.7