Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11683563 . A C CCDS5985.1:NM_004462.3:c.541Att>Ctt_NP_004453.3:p.181I>L Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:151 A:181 1.0 0.006 H -59.1 -51.1 1.0 0.006 0.0 PO4
D99
HOH
 5.885
6.539
3.746
 CD1
N
CG2
 O3
C10
O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 ILE A:151 A:181 10.0 0.057 H -61.8 -43.1 10.0 0.057 0.0 B65
HOH
 9.338
7.163
 N
O
 CAM
O
ILE B:151 B:181 4.0 0.023 H -50.9 -42.9 NA NA NA
ILE C:151 C:181 7.0 0.04 H -65.2 -39.8 NA NA NA
ILE D:151 D:181 5.0 0.029 H -69.7 -44.0 NA NA NA
ILE E:151 E:181 5.0 0.029 H -76.4 -37.2 NA NA NA
ILE F:151 F:181 8.0 0.046 H -52.7 -57.6 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:151 A:181 4.0 0.023 H -75.3 -43.6 4.0 0.023 0.0 PO4
D9A
HOH
 5.872
5.773
3.822
 CD1
N
CG2
 O3
C19
O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:151 A:181 3.0 0.017 H -62.2 -51.8 3.0 0.017 0.0 D61
PO4
HOH
 5.929
5.697
3.624
 N
CD1
CD1
 C7
O3
O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 ILE A:151 A:181 1.0 0.006 H -58.6 -49.1 1.0 0.006 0.0 PO4
D3A
HOH
 5.730
5.612
3.751
 CD1
N
CD1
 O3
O34
O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:154 A:181 8.0 0.046 H -62.6 -44.2 8.0 0.046 0.0 HOH
 3.389
 CG2
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:154 A:181 8.0 0.046 H -57.6 -45.6 8.0 0.046 0.0 HOH
 3.653
 CG2
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:154 A:181 6.0 0.034 H -60.5 -47.3 6.0 0.034 0.0 HOH
 3.561
 CG2
 O
ILE B:154 B:181 9.0 0.051 H -62.8 -45.6 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:154 A:181 8.0 0.046 H -60.3 -44.7 8.0 0.046 0.0 HOH
 3.481
 CG2
 O
ILE B:154 B:181 6.0 0.034 H -66.9 -46.6 6.0 0.034 0.0 HOH
 3.357
 CG2
 O
ILE C:154 C:181 5.0 0.029 H -56.9 -48.0 5.0 0.029 0.0 HOH
 3.501
 CG2
 O
ILE D:154 D:181 5.0 0.029 H -57.8 -51.0 NA NA NA
ILE E:154 E:181 8.0 0.046 H -62.6 -46.4 NA NA NA
ILE F:154 F:181 9.0 0.051 H -65.9 -45.0 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:154 A:181 8.0 0.046 H -62.4 -45.4 8.0 0.046 0.0 ZGA
PO4
HOH
 9.654
5.863
3.402
 N
CD1
CG2
 CAV
O3
O
ILE B:154 B:181 6.0 0.034 H -65.4 -45.5 6.0 0.034 0.0 ZGA
PO4
HOH
 9.477
5.952
3.353
 N
CD1
CG2
 CAV
O3
O
ILE C:154 C:181 7.0 0.04 H -62.4 -46.7 7.0 0.04 0.0 ZGA
PO4
HOH
 9.599
5.893
3.331
 N
CD1
CG2
 CAV
O3
O
ILE D:154 D:181 6.0 0.034 H -59.4 -46.1 NA NA NA
ILE E:154 E:181 6.0 0.034 H -63.5 -46.6 NA NA NA
ILE F:154 F:181 9.0 0.051 H -58.9 -48.5 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:154 A:181 8.0 0.046 H -68.3 -48.7 8.0 0.046 0.0 FPS
FPS
HOH
 5.001
9.371
3.654
 N
N
CG2
 C15
C15
O
ILE B:154 B:181 4.0 0.023 H -64.1 -43.9 4.0 0.023 0.0 FPS
FPS
HOH
 5.123
9.512
3.475
 N
N
CG2
 C15
C12
O
ILE C:154 C:181 6.0 0.034 H -58.3 -46.3 6.0 0.034 0.0 FPS
HOH
 5.487
3.243
 N
CD1
 C15
O
ILE D:154 D:181 7.0 0.04 H -64.3 -44.5 NA NA NA
ILE E:154 E:181 4.0 0.023 H -60.6 -50.7 NA NA NA
ILE F:154 F:181 5.0 0.029 H -68.6 -44.2 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:154 A:181 6.0 0.034 H -67.3 -44.7 6.0 0.034 0.0 FPS
FPS
HOH
 5.122
9.477
3.520
 N
N
CG2
 C15
C14
O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:154 A:181 9.0 0.051 H -61.2 -45.2 9.0 0.051 0.0 PS7
HOH
 5.094
3.423
 N
CG2
 CAC
O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:154 A:181 7.0 0.04 H -66.6 -42.0 7.0 0.04 0.0 PS7
HOH
 5.018
3.703
 N
CG2
 CAC
O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:154 A:181 8.0 0.046 H -65.3 -46.2 8.0 0.046 0.0 PS7
HOH
 5.080
3.568
 N
CG2
 CAC
O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:154 A:181 5.0 0.029 H -62.2 -40.9 5.0 0.029 0.0 PS7
HOH
 5.266
3.840
 N
CA
 CAC
O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 ILE A:151 A:181 6.0 0.034 H -61.3 -44.5 6.0 0.034 0.0 IN0
HOH
 5.547
3.011
 N
O
 C30
O
ILE B:151 B:181 8.0 0.046 H -61.2 -44.2 NA NA NA
ILE C:151 C:181 7.0 0.04 H -62.2 -51.2 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:171 A:181 7.0 0.04 H -64.2 -41.6 7.0 0.04 0.0 FPS
HOH
 5.344
3.878
 N
CA
 C15
O
ILE B:171 B:181 9.0 0.051 H -64.6 -41.1 9.0 0.051 0.0 FPS
HOH
 5.156
3.655
 N
CA
 C15
O
ILE C:171 C:181 5.0 0.029 H -60.5 -42.2 5.0 0.029 0.0 FPS
HOH
 5.453
6.192
 N
CD1
 C15
O
ILE D:171 D:181 7.0 0.04 H -66.5 -52.1 7.0 0.04 0.0 FPS
FPS
HOH
 5.321
9.316
3.790
 N
N
CG2
 C15
C15
O
ILE E:171 E:181 6.0 0.034 H -65.8 -46.4 6.0 0.034 0.0 FPS
HOH
 5.379
3.880
 N
CG1
 C15
O
ILE F:171 F:181 7.0 0.04 H -61.4 -45.5 7.0 0.04 0.0 FPS
HOH
 5.302
3.393
 N
CD1
 C15
O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:171 A:181 9.0 0.051 H -68.5 -37.8 9.0 0.051 0.0 RWY
HOH
 5.890
3.859
 N
CD1
 CAJ
O
ILE B:171 B:181 8.0 0.046 H -73.6 -40.1 8.0 0.046 0.0 RWY
HOH
 5.737
4.416
 N
CD1
 CAJ
O
ILE C:171 C:181 6.0 0.034 H -67.0 -32.2 6.0 0.034 0.0 HOH
 3.779
 CG2
 O
ILE D:171 D:181 8.0 0.046 H -65.7 -39.2 8.0 0.046 0.0 RWY
HOH
 5.984
4.241
 N
CD1
 CAJ
O
ILE E:171 E:181 5.0 0.029 H -70.1 -41.9 5.0 0.029 0.0 RWY
HOH
 5.743
6.805
 N
CD1
 CAJ
O
ILE F:171 F:181 7.0 0.04 H -62.3 -46.4 7.0 0.04 0.0 HOH
 3.760
 CD1
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:171 A:181 6.0 0.034 H -67.0 -46.3 6.0 0.034 0.0 BH8
HOH
 5.942
3.724
 N
O
 CAA
O
ILE B:171 B:181 5.0 0.029 H -69.6 -43.4 5.0 0.029 0.0 BH8
HOH
 5.992
3.782
 N
CG2
 CAK
O
ILE C:171 C:181 6.0 0.034 H -64.4 -42.6 6.0 0.034 0.0 BH8
HOH
 6.029
3.370
 N
CG2
 CAK
O
ILE D:171 D:181 8.0 0.046 H -69.3 -42.5 8.0 0.046 0.0 BH8
HOH
 5.394
3.654
 N
CG2
 CAA
O
ILE E:171 E:181 5.0 0.029 H -69.7 -47.8 5.0 0.029 0.0 BH8
HOH
 5.803
6.200
 N
CD1
 CAK
O
ILE F:171 F:181 7.0 0.04 H -64.5 -41.6 7.0 0.04 0.0 BH8
HOH
 5.631
8.066
 N
O
 CAA
O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:171 A:181 9.0 0.051 H -67.0 -40.1 9.0 0.051 0.0 8PH
8PH
HOH
 5.934
9.532
3.499
 N
N
CA
 CAL
CAL
O
ILE B:171 B:181 7.0 0.04 H -73.3 -36.9 7.0 0.04 0.0 8PH
8PH
HOH
 5.917
9.459
6.639
 N
N
CD1
 CAL
CAA
O
ILE C:171 C:181 5.0 0.029 H -65.6 -45.4 5.0 0.029 0.0 8PH
HOH
 6.068
3.776
 N
O
 CAM
O
ILE D:171 D:181 7.0 0.04 H -66.4 -46.7 7.0 0.04 0.0 8PH
HOH
 5.974
6.851
 N
CD1
 CAL
O
ILE E:171 E:181 7.0 0.04 H -63.8 -36.6 7.0 0.04 0.0 8PH
HOH
 5.723
4.619
 N
CD1
 CAL
O
ILE F:171 F:181 5.0 0.029 H -58.7 -46.5 5.0 0.029 0.0 8PH
8PH
HOH
 5.987
9.646
7.110
 N
N
CD1
 CAL
CAL
O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:171 A:181 8.0 0.046 H -66.7 -44.3 8.0 0.046 0.0 BH5
HOH
 6.078
3.677
 N
CD1
 CAM
O
ILE B:171 B:181 5.0 0.029 H -67.3 -43.0 5.0 0.029 0.0 BH5
HOH
 6.158
3.795
 N
CG2
 CAM
O
ILE C:171 C:181 5.0 0.029 H -69.4 -37.1 5.0 0.029 0.0 BH5
HOH
 5.892
3.482
 N
CG2
 CAM
O
ILE D:171 D:181 8.0 0.046 H -69.8 -41.1 8.0 0.046 0.0 BH5
HOH
 5.942
3.796
 N
CG2
 CAM
O
ILE E:171 E:181 5.0 0.029 H -64.5 -44.2 5.0 0.029 0.0 BH5
HOH
 6.172
3.495
 N
O
 CAM
O
ILE F:171 F:181 7.0 0.04 H -62.7 -40.6 7.0 0.04 0.0 BH5
HOH
 6.123
3.643
 N
CD1
 CAM
O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:171 A:181 9.0 0.051 H -66.7 -44.2 9.0 0.051 0.0 E5S
HOH
 6.012
3.680
 N
O
 CAA
O
ILE B:171 B:181 9.0 0.051 H -62.7 -44.1 9.0 0.051 0.0 E5S
HOH
 6.089
3.849
 N
CG2
 CAA
O
ILE C:171 C:181 8.0 0.046 H -66.1 -45.9 8.0 0.046 0.0 E5S
HOH
 5.733
3.520
 N
CG2
 CAA
O
ILE D:171 D:181 8.0 0.046 H -65.2 -45.4 8.0 0.046 0.0 E5S
HOH
 5.642
3.624
 N
CG2
 CAA
O
ILE E:171 E:181 8.0 0.046 H -69.0 -46.4 8.0 0.046 0.0 E5S
HOH
 5.915
4.320
 N
CD1
 CAA
O
ILE F:171 F:181 8.0 0.046 H -70.1 -43.9 8.0 0.046 0.0 E5S
HOH
 6.198
7.468
 N
O
 CAA
O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:171 A:181 6.0 0.034 H -65.2 -46.7 6.0 0.034 0.0 BH3
HOH
 6.213
4.005
 N
O
 CAL
O
ILE B:171 B:181 7.0 0.04 H -69.4 -42.5 7.0 0.04 0.0 HOH
 3.782
 CG2
 O
ILE C:171 C:181 5.0 0.029 H -64.7 -43.4 5.0 0.029 0.0 HOH
 3.467
 CG2
 O
ILE D:171 D:181 10.0 0.057 H -67.6 -40.3 10.0 0.057 0.0 HOH
 3.802
 O
 O
ILE E:171 E:181 5.0 0.029 H -68.6 -45.7 5.0 0.029 0.0 HOH
 3.893
 CG2
 O
ILE F:171 F:181 6.0 0.034 H -61.5 -44.5 6.0 0.034 0.0 HOH
 4.113
 CA
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:171 A:181 8.0 0.046 H -62.5 -47.2 8.0 0.046 0.0 ER4
HOH
 5.424
3.917
 N
O
 OAV
O
ILE B:171 B:181 7.0 0.04 H -62.3 -49.4 7.0 0.04 0.0 ER4
HOH
 5.473
3.482
 N
CG2
 OAV
O
ILE C:171 C:181 8.0 0.046 H -63.6 -44.5 8.0 0.046 0.0 ER4
HOH
 5.457
3.580
 N
CG2
 OAV
O
ILE D:171 D:181 9.0 0.051 H -63.0 -47.0 9.0 0.051 0.0 ER4
HOH
 5.457
3.535
 N
CG2
 OAV
O
ILE E:171 E:181 10.0 0.057 H -67.1 -45.6 10.0 0.057 0.0 ER4
HOH
 5.396
3.439
 N
CG2
 OAV
O
ILE F:171 F:181 7.0 0.04 H -67.1 -45.1 7.0 0.04 0.0 ER4
HOH
 5.287
4.202
 N
O
 OAV
O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 ILE A:171 A:181 8.0 0.046 H -70.4 -33.2 8.0 0.046 0.0 RWZ
HOH
 5.579
3.695
 N
CD1
 CAA
O
ILE B:171 B:181 12.0 0.069 H -68.1 -43.4 12.0 0.069 0.0 RWZ
HOH
 5.728
6.460
 N
CD1
 CAD
O
ILE C:171 C:181 7.0 0.04 H -61.4 -40.4 7.0 0.04 0.0 RWZ
HOH
 5.348
6.145
 N
CD1
 CAA
O
ILE D:171 D:181 8.0 0.046 H -74.3 -47.5 8.0 0.046 0.0 HOH
 6.161
 N
 O
ILE E:171 E:181 5.0 0.029 H -64.7 -40.8 5.0 0.029 0.0 RWZ
HOH
 5.627
4.573
 N
CD1
 CAA
O
ILE F:171 F:181 7.0 0.04 H -64.6 -31.4 7.0 0.04 0.0 HOH
 5.679
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 ILE A:181 A:181 7.0 0.04 H -62.5 -45.4