Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11683597 . T A CCDS5985.1:NM_004462.3:c.575tTt>tAt_NP_004453.3:p.192F>Y Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 PHE A:162 A:192 82.0 0.39 S -76.4 -21.5 82.0 0.39 0.0 HOH
 2.716
 O
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 PHE A:162 A:192 78.0 0.371 S -79.4 -20.0 78.0 0.371 0.0 HOH
 6.517
 CE2
 O
PHE B:162 B:192 76.0 0.362 S -66.5 -31.4 NA NA NA
PHE C:162 C:192 69.0 0.329 S -76.7 -30.7 NA NA NA
PHE D:162 D:192 68.0 0.324 S -70.7 -20.2 NA NA NA
PHE E:162 E:192 72.0 0.343 S -65.9 -23.4 NA NA NA
PHE F:162 F:192 63.0 0.3 S -91.8 -17.8 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 PHE A:162 A:192 68.0 0.324 S -73.9 -22.7 68.0 0.324 0.0 HOH
 3.286
 CD2
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 PHE A:162 A:192 74.0 0.352 S -74.5 -24.8 74.0 0.352 0.0 HOH
 2.799
 O
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 PHE A:162 A:192 76.0 0.362 S -77.6 -22.2 76.0 0.362 0.0 HOH
 2.565
 O
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 PHE A:165 A:192 80.0 0.381 S -75.1 -20.0 80.0 0.381 0.0 HOH
 3.507
 CE2
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 PHE A:165 A:192 61.0 0.29 S -77.5 -17.1 61.0 0.29 0.0 HOH
 2.863
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 PHE A:165 A:192 60.0 0.286 S -76.3 -22.5 60.0 0.286 0.0 HOH
 2.819
 O
 O
PHE B:165 B:192 57.0 0.271 S -78.2 -19.4 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 PHE A:165 A:192 80.0 0.381 S -70.2 -30.2 80.0 0.381 0.0 HOH
 2.879
 O
 O
PHE B:165 B:192 78.0 0.371 S -74.7 -20.9 78.0 0.371 0.0 HOH
 2.894
 O
 O
PHE C:165 C:192 74.0 0.352 S -78.2 -20.5 74.0 0.352 0.0 HOH
 3.285
 O
 O
PHE D:165 D:192 78.0 0.371 S -68.2 -24.5 NA NA NA
PHE E:165 E:192 70.0 0.333 S -78.8 -23.3 NA NA NA
PHE F:165 F:192 74.0 0.352 S -69.2 -29.0 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 PHE A:165 A:192 79.0 0.376 S -71.6 -26.6 79.0 0.376 0.0 HOH
 2.848
 O
 O
PHE B:165 B:192 74.0 0.352 S -72.3 -24.5 74.0 0.352 0.0 MG
HOH
 4.717
2.835
 N
O
 MG
O
PHE C:165 C:192 65.0 0.31 S -78.0 -21.1 65.0 0.31 0.0 HOH
 2.869
 O
 O
PHE D:165 D:192 72.0 0.343 S -74.9 -20.8 NA NA NA
PHE E:165 E:192 75.0 0.357 S -72.5 -23.0 NA NA NA
PHE F:165 F:192 82.0 0.39 S -76.0 -24.7 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 PHE A:165 A:192 80.0 0.381 S -70.1 -31.2 80.0 0.381 0.0 HOH
 2.726
 O
 O
PHE B:165 B:192 75.0 0.357 S -72.5 -19.1 75.0 0.357 0.0 HOH
 4.629
 CZ
 O
PHE C:165 C:192 75.0 0.357 S -78.6 -26.2 75.0 0.357 0.0 HOH
 3.297
 CD1
 O
PHE D:165 D:192 76.0 0.362 S -60.7 -22.6 NA NA NA
PHE E:165 E:192 75.0 0.357 S -77.6 -24.9 NA NA NA
PHE F:165 F:192 81.0 0.386 S -73.9 -26.9 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 PHE A:165 A:192 78.0 0.371 S -70.2 -23.4 78.0 0.371 0.0 HOH
 3.851
 CD1
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 PHE A:165 A:192 80.0 0.381 S -71.7 -21.8 80.0 0.381 0.0 HOH
 2.660
 O
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 PHE A:165 A:192 78.0 0.371 S -67.1 -28.8 78.0 0.371 0.0 HOH
 2.644
 O
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 PHE A:165 A:192 79.0 0.376 S -71.0 -20.9 79.0 0.376 0.0 HOH
 3.519
 CE2
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 PHE A:165 A:192 81.0 0.386 S -67.2 -19.7 81.0 0.386 0.0 HOH
 3.483
 CE2
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 PHE A:162 A:192 74.0 0.352 S -73.7 -20.1 74.0 0.352 0.0 HOH
 3.054
 CD1
 O
PHE B:162 B:192 73.0 0.348 S -74.4 -23.0 NA NA NA
PHE C:162 C:192 63.0 0.3 S -78.8 -21.7 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:182 A:192 86.0 0.41 S -65.1 -33.8 86.0 0.41 0.0 HOH
 3.755
 CZ
 O
PHE B:182 B:192 69.0 0.329 S -82.9 -25.6 65.0 0.31 0.019 D:P37268:0.019
 HOH
 3.718
 O
 O
PHE C:182 C:192 73.0 0.348 S -80.6 -18.4 39.0 0.186 0.162 F:P37268:0.162
 HOH
 3.484
 CE2
 O
PHE D:182 D:192 73.0 0.348 S -77.5 -24.8 69.0 0.329 0.019 B:P37268:0.019
 HOH
 3.330
 CD1
 O
PHE E:182 E:192 74.0 0.352 S -74.5 -22.2 31.0 0.148 0.204 A:P37268:0.205
 HOH
 3.694
 N
 O
PHE F:182 F:192 82.0 0.39 S -105.8 -11.9 82.0 0.39 0.0 HOH
 3.665
 CZ
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:182 A:192 78.0 0.371 S -74.1 -26.9 78.0 0.371 0.0 HOH
 3.363
 CE2
 O
PHE B:182 B:192 67.0 0.319 S -74.1 -31.9 67.0 0.319 0.0 HOH
 3.480
 O
 O
PHE C:182 C:192 74.0 0.352 S -87.7 -20.0 49.0 0.233 0.119 F:P37268:0.119
 HOH
 2.960
 O
 O
PHE D:182 D:192 73.0 0.348 S -71.6 -23.5 73.0 0.348 0.0 HOH
 3.099
 O
 O
PHE E:182 E:192 76.0 0.362 S -90.0 -12.6 37.0 0.176 0.186 A:P37268:0.186
 HOH
 4.084
 CE1
 O
PHE F:182 F:192 73.0 0.348 S -94.1 -14.2 73.0 0.348 0.0 HOH
 3.306
 O
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:182 A:192 82.0 0.39 S -69.5 -23.9 81.0 0.386 0.004 E:P37268:0.005
 HOH
 2.732
 O
 O
PHE B:182 B:192 79.0 0.376 S -77.3 -20.0 67.0 0.319 0.057 D:P37268:0.057
 HOH
 3.115
 O
 O
PHE C:182 C:192 81.0 0.386 S -73.2 -18.6 41.0 0.195 0.191 F:P37268:0.19
 HOH
 2.892
 O
 O
PHE D:182 D:192 76.0 0.362 S -71.4 -13.4 63.0 0.3 0.062 B:P37268:0.062
 HOH
 3.347
 CE2
 O
PHE E:182 E:192 73.0 0.348 S -71.7 -19.8 31.0 0.148 0.2 A:P37268:0.2
 HOH
 2.984
 O
 O
PHE F:182 F:192 79.0 0.376 S -88.7 -22.8 79.0 0.376 0.0 HOH
 2.764
 O
 O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:182 A:192 67.0 0.319 S -72.5 -25.4 67.0 0.319 0.0 HOH
 2.893
 O
 O
PHE B:182 B:192 73.0 0.348 S -72.5 -22.2 73.0 0.348 0.0 HOH
 3.139
 O
 O
PHE C:182 C:192 77.0 0.367 S -79.1 -13.9 50.0 0.238 0.129 F:P37268:0.129
 HOH
 2.574
 O
 O
PHE D:182 D:192 74.0 0.352 S -74.1 -18.4 74.0 0.352 0.0 HOH
 3.223
 CE2
 O
PHE E:182 E:192 67.0 0.319 S -73.9 -13.7 18.0 0.086 0.233 A:P37268:0.233
 HOH
 4.012
 CZ
 O
PHE F:182 F:192 63.0 0.3 S -80.0 -23.8 63.0 0.3 0.0 HOH
 3.377
 CE1
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:182 A:192 80.0 0.381 S -72.4 -31.4 80.0 0.381 0.0 HOH
 2.797
 O
 O
PHE B:182 B:192 64.0 0.305 S -70.8 -24.3 64.0 0.305 0.0 HOH
 2.885
 O
 O
PHE C:182 C:192 76.0 0.362 S -75.8 -15.5 45.0 0.214 0.148 F:P37268:0.148
 HOH
 2.915
 O
 O
PHE D:182 D:192 71.0 0.338 S -72.0 -22.7 68.0 0.324 0.014 B:P37268:0.014
 HOH
 3.348
 CZ
 O
PHE E:182 E:192 64.0 0.305 S -75.3 -14.7 18.0 0.086 0.219 A:P37268:0.219
 HOH
 2.796
 O
 O
PHE F:182 F:192 76.0 0.362 S -84.5 -18.2 76.0 0.362 0.0 HOH
 2.908
 O
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:182 A:192 80.0 0.381 S -70.2 -23.0 80.0 0.381 0.0 HOH
 2.649
 O
 O
PHE B:182 B:192 71.0 0.338 S -78.8 -20.6 67.0 0.319 0.019 D:P37268:0.019
 HOH
 3.124
 O
 O
PHE C:182 C:192 77.0 0.367 S -81.8 -15.0 51.0 0.243 0.124 F:P37268:0.124
 HOH
 2.909
 O
 O
PHE D:182 D:192 73.0 0.348 S -69.3 -22.2 70.0 0.333 0.015 B:P37268:0.014
 HOH
 3.504
 CE2
 O
PHE E:182 E:192 75.0 0.357 S -66.3 -25.8 40.0 0.19 0.167 A:P37268:0.167
 HOH
 5.178
 O
 O
PHE F:182 F:192 83.0 0.395 S -80.3 -22.7 83.0 0.395 0.0 HOH
 2.959
 O
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:182 A:192 80.0 0.381 S -72.7 -26.5 80.0 0.381 0.0 HOH
 2.784
 O
 O
PHE B:182 B:192 74.0 0.352 S -75.8 -23.8 73.0 0.348 0.004 D:P37268:0.005
 HOH
 3.135
 O
 O
PHE C:182 C:192 76.0 0.362 S -79.6 -13.1 43.0 0.205 0.157 F:P37268:0.157
 HOH
 2.990
 O
 O
PHE D:182 D:192 74.0 0.352 S -72.7 -22.5 73.0 0.348 0.004 B:P37268:0.005
 HOH
 3.114
 O
 O
PHE E:182 E:192 76.0 0.362 S -74.3 -14.2 33.0 0.157 0.205 A:P37268:0.205
 HOH
 2.866
 O
 O
PHE F:182 F:192 83.0 0.395 S -77.6 -18.7 83.0 0.395 0.0 HOH
 2.870
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:182 A:192 79.0 0.376 S -71.6 -26.5 79.0 0.376 0.0 HOH
 2.713
 O
 O
PHE B:182 B:192 74.0 0.352 S -75.7 -18.6 71.0 0.338 0.014 D:P37268:0.014
 HOH
 3.035
 O
 O
PHE C:182 C:192 76.0 0.362 S -79.2 -15.2 57.0 0.271 0.091 F:P37268:0.09
 HOH
 2.800
 O
 O
PHE D:182 D:192 74.0 0.352 S -72.9 -19.5 70.0 0.333 0.019 B:P37268:0.019
 HOH
 3.277
 O
 O
PHE E:182 E:192 77.0 0.367 S -71.0 -20.6 42.0 0.2 0.167 A:P37268:0.167
 HOH
 2.882
 O
 O
PHE F:182 F:192 82.0 0.39 S -76.0 -18.1 82.0 0.39 0.0 HOH
 2.786
 O
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 PHE A:182 A:192 71.0 0.338 S -74.8 -30.6 71.0 0.338 0.0 HOH
 3.480
 O
 O
PHE B:182 B:192 74.0 0.352 S -76.1 -30.0 74.0 0.352 0.0 HOH
 3.682
 CE1
 O
PHE C:182 C:192 72.0 0.343 S -79.5 -8.0 42.0 0.2 0.143 F:P37268:0.143
 HOH
 4.273
 O
 O
PHE D:182 D:192 72.0 0.343 S -71.4 -16.8 72.0 0.343 0.0 HOH
 3.310
 CE1
 O
PHE E:182 E:192 79.0 0.376 S -92.3 -21.1 40.0 0.19 0.186 A:P37268:0.186
 HOH
 3.258
 O
 O
PHE F:182 F:192 79.0 0.376 S -83.2 -21.3 79.0 0.376 0.0 HOH
 3.516
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 PHE A:192 A:192 60.0 0.286 S -69.1 -22.7