Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11683695 . C A CCDS5985.1:NM_004462.3:c.673Caa>Aaa_NP_004453.3:p.225Q>K Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLN A:195 A:225 140.0 0.778 H -48.8 -47.9 140.0 0.778 0.0 HOH
 3.034
 CB
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 GLN A:195 A:225 155.0 0.861 H -105.5 -13.3 155.0 0.861 0.0 HOH
 5.442
 N
 O
GLN B:195 B:225 148.0 0.822 H -59.5 -33.3 NA NA NA
GLN C:195 C:225 85.0 NA H -76.9 -45.5 NA NA NA
GLN D:195 D:225 174.0 0.967 H -40.8 -39.5 NA NA NA
GLN E:195 E:225 161.0 0.894 H -57.7 -32.2 NA NA NA
GLN F:195 NA:NA DO NA DO DO DO NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLN A:195 A:225 155.0 0.861 H -60.1 -33.5 155.0 0.861 0.0 HOH
 4.497
 OE1
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLN A:195 A:225 146.0 0.811 T -72.8 -2.9 146.0 0.811 0.0 HOH
 2.747
 NE2
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 GLN A:195 A:225 150.0 0.833 H -67.4 -21.9 150.0 0.833 0.0 HOH
 2.665
 OE1
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLN A:198 A:225 148.0 0.822 H -76.1 -22.4 148.0 0.822 0.0 HOH
 3.344
 CB
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLN A:198 A:225 156.0 0.867 H -67.4 -25.0 156.0 0.867 0.0 HOH
 2.377
 OE1
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLN A:198 A:225 153.0 0.85 H -69.8 -19.7 153.0 0.85 0.0 HOH
 2.632
 OE1
 O
GLN B:198 B:225 154.0 0.856 H -65.3 -23.0 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLN A:198 A:225 144.0 0.8 H -59.1 -19.6 144.0 0.8 0.0 HOH
 6.442
 N
 O
GLN B:198 B:225 151.0 0.839 H -59.5 -26.7 151.0 0.839 0.0 HOH
 4.688
 NE2
 O
GLN C:198 C:225 146.0 0.811 H -72.6 -16.3 146.0 0.811 0.0 HOH
 6.441
 C
 O
GLN D:198 D:225 150.0 0.833 H -68.9 -21.0 NA NA NA
GLN E:198 E:225 177.0 0.983 H -53.0 -58.7 NA NA NA
GLN F:198 F:225 142.0 0.789 T -86.0 -10.1 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLN A:198 A:225 152.0 0.844 H -70.3 -25.3 152.0 0.844 0.0 HOH
 5.948
 N
 O
GLN B:198 B:225 149.0 0.828 H -79.6 -14.8 149.0 0.828 0.0 HOH
 5.232
 NE2
 O
GLN C:198 C:225 148.0 0.822 H -69.0 -24.7 148.0 0.822 0.0 HOH
 5.867
 N
 O
GLN D:198 D:225 152.0 0.844 H -61.0 -34.5 NA NA NA
GLN E:198 E:225 148.0 0.822 H -54.3 -42.1 NA NA NA
GLN F:198 F:225 150.0 0.833 H -69.7 -21.3 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLN A:198 A:225 151.0 0.839 T -96.9 22.8 151.0 0.839 0.0 HOH
 8.332
 OE1
 O
GLN B:198 B:225 156.0 0.867 T -63.9 -16.5 156.0 0.867 0.0 HOH
 6.458
 NE2
 O
GLN C:198 C:225 154.0 0.856 T -60.7 -9.0 154.0 0.856 0.0
GLN D:198 D:225 150.0 0.833 H -71.6 -20.1 NA NA NA
GLN E:198 E:225 152.0 0.844 H -56.3 -42.1 NA NA NA
GLN F:198 F:225 175.0 0.972 T -70.4 97.1 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLN A:198 A:225 151.0 0.839 H -68.5 -34.1 151.0 0.839 0.0 HOH
 2.855
 NE2
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLN A:198 A:225 149.0 0.828 H -72.6 -19.3 149.0 0.828 0.0 HOH
 3.351
 CB
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLN A:198 A:225 153.0 0.85 H -62.2 -23.8 153.0 0.85 0.0 HOH
 2.791
 OE1
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLN A:198 A:225 149.0 0.828 H -67.3 -28.7 149.0 0.828 0.0 HOH
 3.043
 OE1
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLN A:198 A:225 142.0 0.789 H -71.1 -26.5 142.0 0.789 0.0 HOH
 2.966
 OE1
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 GLN A:195 A:225 143.0 0.794 H -63.0 -24.3 143.0 0.794 0.0 HOH
 5.607
 NE2
 O
GLN B:195 B:225 167.0 0.928 H -60.6 -38.1 NA NA NA
GLN C:195 C:225 147.0 0.817 H -59.5 -29.0 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:215 A:225 160.0 0.889 T -79.0 8.7 160.0 0.889 0.0 HOH
 4.091
 O
 O
GLN B:215 B:225 150.0 0.833 T -82.1 29.9 150.0 0.833 0.0 HOH
 7.901
 C
 O
GLN C:215 C:225 155.0 0.861 T -84.5 45.6 155.0 0.861 0.0 HOH
 4.268
 OE1
 O
GLN D:215 D:225 146.0 0.811 T -77.1 17.4 146.0 0.811 0.0 FPS
HOH
 9.793
3.090
 O
O
 O1B
O
GLN E:215 E:225 145.0 0.806 H -52.1 -40.3 145.0 0.806 0.0 HOH
 3.300
 O
 O
GLN F:215 F:225 151.0 0.839 T -66.0 5.0 151.0 0.839 0.0 HOH
 3.664
 OE1
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:215 A:225 155.0 0.861 T -71.9 38.3 155.0 0.861 0.0 HOH
 3.197
 CG
 O
GLN B:215 B:225 163.0 0.906 T -69.2 7.8 163.0 0.906 0.0 HOH
 5.279
 O
 O
GLN C:215 C:225 155.0 0.861 T -75.0 11.0 155.0 0.861 0.0 HOH
 4.165
 NE2
 O
GLN D:215 D:225 156.0 0.867 H -95.5 -17.1 156.0 0.867 0.0 HOH
 4.709
 OE1
 O
GLN E:215 E:225 149.0 0.828 H -75.2 -11.0 149.0 0.828 0.0 HOH
 2.741
 O
 O
GLN F:215 F:225 153.0 0.85 T -74.5 25.0 153.0 0.85 0.0 HOH
 5.979
 NE2
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:215 A:225 156.0 0.867 T -62.0 -9.4 156.0 0.867 0.0 HOH
 5.596
 N
 O
GLN B:215 B:225 145.0 0.806 T -67.2 -4.1 145.0 0.806 0.0
GLN C:215 C:225 155.0 0.861 T -71.7 -10.9 155.0 0.861 0.0 HOH
 3.516
 OE1
 O
GLN D:215 D:225 147.0 0.817 T -67.3 1.7 147.0 0.817 0.0 HOH
 8.402
 N
 O
GLN E:215 E:225 148.0 0.822 T -64.6 -16.1 148.0 0.822 0.0 HOH
 6.628
 NE2
 O
GLN F:215 F:225 154.0 0.856 T -69.4 5.0 154.0 0.856 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:215 A:225 153.0 0.85 T -63.3 -11.5 153.0 0.85 0.0 HOH
 9.653
 O
 O
GLN B:215 B:225 155.0 0.861 T -71.7 2.5 155.0 0.861 0.0 HOH
 8.543
 O
 O
GLN C:215 C:225 150.0 0.833 T -75.4 -15.8 150.0 0.833 0.0 HOH
 4.405
 NE2
 O
GLN D:215 D:225 143.0 0.794 H -64.5 -37.6 143.0 0.794 0.0
GLN E:215 E:225 140.0 0.778 H -64.0 -22.4 140.0 0.778 0.0 HOH
 7.522
 OE1
 O
GLN F:215 F:225 165.0 0.917 H -63.9 -19.0 165.0 0.917 0.0 HOH
 8.065
 NE2
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:215 A:225 148.0 0.822 T -79.2 60.5 148.0 0.822 0.0 HOH
 3.355
 O
 O
GLN B:215 B:225 160.0 0.889 H -80.9 -19.9 160.0 0.889 0.0 HOH
 3.398
 CA
 O
GLN C:215 C:225 153.0 0.85 T -72.3 -13.8 153.0 0.85 0.0 HOH
 3.138
 NE2
 O
GLN D:215 D:225 151.0 0.839 T -82.1 30.2 151.0 0.839 0.0 HOH
 3.410
 NE2
 O
GLN E:215 E:225 145.0 0.806 T -71.9 -9.7 145.0 0.806 0.0 HOH
 3.741
 O
 O
GLN F:215 F:225 145.0 0.806 T -73.7 27.5 145.0 0.806 0.0 HOH
 8.188
 OE1
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:215 A:225 152.0 0.844 T -71.3 -11.3 152.0 0.844 0.0 HOH
 5.160
 NE2
 O
GLN B:215 B:225 151.0 0.839 T -75.6 -6.9 151.0 0.839 0.0 HOH
 7.982
 N
 O
GLN C:215 C:225 154.0 0.856 T -73.9 -0.3 154.0 0.856 0.0 HOH
 4.140
 NE2
 O
GLN D:215 D:225 148.0 0.822 T -76.6 36.2 148.0 0.822 0.0 HOH
 3.193
 NE2
 O
GLN E:215 E:225 155.0 0.861 H -61.4 -10.6 155.0 0.861 0.0 HOH
 3.662
 NE2
 O
GLN F:215 F:225 153.0 0.85 T -76.5 16.8 153.0 0.85 0.0
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:215 A:225 160.0 0.889 T -68.7 -6.1 160.0 0.889 0.0 HOH
 5.615
 O
 O
GLN B:215 B:225 165.0 0.917 H -84.6 -28.9 165.0 0.917 0.0 HOH
 4.290
 CA
 O
GLN C:215 C:225 152.0 0.844 T -79.1 19.2 152.0 0.844 0.0 HOH
 3.761
 O
 O
GLN D:215 D:225 160.0 0.889 T -80.2 37.5 160.0 0.889 0.0 HOH
 3.380
 NE2
 O
GLN E:215 E:225 149.0 0.828 T -67.0 2.8 149.0 0.828 0.0 HOH
 4.050
 CB
 O
GLN F:215 F:225 143.0 0.794 T -77.3 25.0 143.0 0.794 0.0 HOH
 7.827
 OE1
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLN A:215 A:225 150.0 0.833 T -80.2 -8.3 150.0 0.833 0.0 HOH
 5.196
 NE2
 O
GLN B:215 B:225 149.0 0.828 T -75.6 -2.4 149.0 0.828 0.0 HOH
 4.395
 O
 O
GLN C:215 C:225 147.0 0.817 T -81.7 -5.7 147.0 0.817 0.0 HOH
 4.050
 NE2
 O
GLN D:215 D:225 149.0 0.828 T -78.6 25.2 149.0 0.828 0.0 HOH
 7.753
 OE1
 O
GLN E:215 E:225 150.0 0.833 H -66.9 -16.6 150.0 0.833 0.0 HOH
 6.769
 NE2
 O
GLN F:215 F:225 154.0 0.856 T -80.6 21.6 154.0 0.856 0.0
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 GLN A:215 A:225 153.0 0.85 T -84.1 47.2 153.0 0.85 0.0 HOH
 3.797
 CG
 O
GLN B:215 B:225 165.0 0.917 T -81.4 -7.7 165.0 0.917 0.0 HOH
 8.334
 O
 O
GLN C:215 C:225 147.0 0.817 T -94.0 14.3 147.0 0.817 0.0 HOH
 5.953
 O
 O
GLN D:215 D:225 140.0 0.778 T -87.7 -6.6 140.0 0.778 0.0 HOH
 7.827
 OE1
 O
GLN E:215 E:225 148.0 0.822 T -75.0 5.6 148.0 0.822 0.0
GLN F:215 F:225 149.0 0.828 T -82.3 31.0 149.0 0.828 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 GLN A:225 A:225 143.0 0.794 H -65.5 -31.6