Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11687804 . A C CCDS5985.1:NM_004462.3:c.754Att>Ctt_NP_004453.3:p.252I>L Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:222 A:252 34.0 0.194 H -59.0 -34.2 34.0 0.194 0.0 HOH
 3.103
 CG2
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 ILE A:222 A:252 31.0 0.177 H -47.7 -38.6 31.0 0.177 0.0 HOH
 3.499
 CG2
 O
ILE B:222 B:252 29.0 0.166 H -57.7 -23.8 NA NA NA
ILE C:222 C:252 46.0 0.263 G -95.9 -32.5 NA NA NA
ILE D:222 D:252 37.0 NA H -59.4 -42.8 NA NA NA
ILE E:222 E:252 26.0 0.149 H -33.9 -49.8 NA NA NA
ILE F:222 NA:NA DO NA DO DO DO NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:222 A:252 29.0 0.166 H -63.5 -27.2 29.0 0.166 0.0 HOH
 3.165
 CG2
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ILE A:222 A:252 35.0 0.2 H -63.2 -35.4 35.0 0.2 0.0 HOH
 3.240
 CA
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 ILE A:222 A:252 42.0 0.24 H -63.1 -33.1 42.0 0.24 0.0 HOH
 3.379
 CG2
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:225 A:252 27.0 0.154 H -58.2 -37.5 27.0 0.154 0.0 HOH
 3.405
 CA
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:225 A:252 28.0 0.16 H -62.9 -37.3 28.0 0.16 0.0 HOH
 3.230
 CA
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:225 A:252 20.0 0.114 H -53.0 -34.4 20.0 0.114 0.0 HOH
 3.164
 CA
 O
ILE B:225 B:252 28.0 0.16 H -66.5 -37.7 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:225 A:252 31.0 0.177 H -52.2 -42.7 31.0 0.177 0.0 HOH
 3.918
 N
 O
ILE B:225 B:252 27.0 0.154 H -56.9 -43.7 27.0 0.154 0.0 HOH
 6.887
 CG1
 O
ILE C:225 C:252 37.0 0.211 H -59.2 -38.9 37.0 0.211 0.0 HOH
 9.766
 N
 O
ILE D:225 D:252 22.0 0.126 H -55.7 -39.7 NA NA NA
ILE E:225 E:252 17.0 0.097 H -77.3 -30.0 NA NA NA
ILE F:225 F:252 29.0 0.166 H -64.1 -24.4 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ILE A:225 A:252 29.0 0.166 H -58.0 -44.0 29.0 0.166 0.0 HOH
 3.321
 N
 O
ILE B:225 B:252 31.0 0.177 H -60.0 -36.7 31.0 0.177 0.0 HOH
 3.300
 CA
 O
ILE C:225 C:252 21.0 0.12 H -61.2 -36.6 21.0 0.12 0.0 HOH
 3.294
 CA
 O
ILE D:225 D:252 17.0 0.097 H -56.9 -41.0 NA NA NA
ILE E:225 E:252 23.0 0.131 H -61.5 -38.8 NA NA NA
ILE F:225 F:252 29.0 0.166 H -53.9 -39.2 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:225 A:252 25.0 0.143 H -62.3 -36.7 25.0 0.143 0.0 HOH
 3.626
 N
 O
ILE B:225 B:252 24.0 0.137 H -58.7 -39.8 24.0 0.137 0.0 HOH
 9.243
 N
 O
ILE C:225 C:252 25.0 0.143 H -49.1 -27.4 25.0 0.143 0.0
ILE D:225 D:252 26.0 0.149 H -61.6 -39.6 NA NA NA
ILE E:225 E:252 40.0 0.229 H -53.4 -48.6 NA NA NA
ILE F:225 F:252 33.0 0.189 H -73.1 -32.5 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:225 A:252 36.0 0.206 H -58.4 -38.7 36.0 0.206 0.0 HOH
 3.293
 CD1
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ILE A:225 A:252 25.0 0.143 H -55.9 -39.6 25.0 0.143 0.0 HOH
 3.402
 CA
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:225 A:252 37.0 0.211 H -50.0 -42.8 37.0 0.211 0.0 HOH
 2.918
 CD1
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:225 A:252 36.0 0.206 H -58.7 -36.9 36.0 0.206 0.0 HOH
 3.419
 CG2
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ILE A:225 A:252 35.0 0.2 H -60.7 -36.1 35.0 0.2 0.0 HOH
 3.223
 N
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 ILE A:222 A:252 30.0 0.171 H -60.1 -41.3 30.0 0.171 0.0 HOH
 3.394
 N
 O
ILE B:222 B:252 43.0 0.246 H -57.4 -35.1 NA NA NA
ILE C:222 C:252 33.0 0.189 H -56.2 -48.6 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:242 A:252 22.0 0.126 H -40.2 -42.5 22.0 0.126 0.0 HOH
 6.482
 CG2
 O
ILE B:242 B:252 14.0 0.08 H -32.6 -38.8 14.0 0.08 0.0
ILE C:242 C:252 23.0 0.131 H -38.4 -37.2 23.0 0.131 0.0 HOH
 5.015
 O
 O
ILE D:242 D:252 17.0 0.097 H -66.4 -34.8 17.0 0.097 0.0 HOH
 5.904
 CG2
 O
ILE E:242 E:252 20.0 0.114 H -56.7 -41.4 20.0 0.114 0.0 HOH
 4.243
 CD1
 O
ILE F:242 F:252 57.0 0.326 H -7.3 -60.7 57.0 0.326 0.0
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:242 A:252 22.0 0.126 H -58.2 -42.1 22.0 0.126 0.0 HOH
 5.840
 O
 O
ILE B:242 B:252 21.0 0.12 H -48.9 -39.6 21.0 0.12 0.0 HOH
 4.383
 CG2
 O
ILE C:242 C:252 28.0 0.16 H -44.9 -48.2 28.0 0.16 0.0 HOH
 6.646
 CG1
 O
ILE D:242 D:252 12.0 0.069 H -43.2 -2.9 12.0 0.069 0.0 HOH
 5.139
 CG2
 O
ILE E:242 E:252 23.0 0.131 H -34.8 -63.0 23.0 0.131 0.0 HOH
 7.460
 O
 O
ILE F:242 F:252 38.0 0.217 H -48.5 -36.2 38.0 0.217 0.0 HOH
 5.402
 N
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:242 A:252 22.0 0.126 H -52.5 -43.7 22.0 0.126 0.0 HOH
 5.920
 CG2
 O
ILE B:242 B:252 22.0 0.126 H -47.4 -33.4 22.0 0.126 0.0
ILE C:242 C:252 17.0 0.097 H -40.9 -46.4 17.0 0.097 0.0
ILE D:242 D:252 23.0 0.131 H -45.0 -33.8 23.0 0.131 0.0 HOH
 6.463
 CD1
 O
ILE E:242 E:252 18.0 0.103 H -56.0 -42.8 18.0 0.103 0.0 HOH
 3.868
 CD1
 O
ILE F:242 F:252 26.0 0.149 H -50.7 -39.7 26.0 0.149 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:242 A:252 27.0 0.154 H -28.3 -46.8 27.0 0.154 0.0 HOH
 4.316
 O
 O
ILE B:242 B:252 23.0 0.131 H -37.8 -48.2 23.0 0.131 0.0
ILE C:242 C:252 33.0 0.189 H -37.2 -41.2 33.0 0.189 0.0
ILE D:242 D:252 19.0 0.109 H -41.6 -20.3 19.0 0.109 0.0
ILE E:242 E:252 22.0 0.126 H -57.7 -41.4 22.0 0.126 0.0 HOH
 7.459
 CG1
 O
ILE F:242 F:252 22.0 0.126 H -28.5 -42.7 22.0 0.126 0.0
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:242 A:252 23.0 0.131 H -45.2 -46.2 23.0 0.131 0.0 HOH
 3.779
 CG2
 O
ILE B:242 B:252 25.0 0.143 H -50.4 -40.7 25.0 0.143 0.0 HOH
 3.150
 CD1
 O
ILE C:242 C:252 22.0 0.126 H -52.0 -41.3 22.0 0.126 0.0 HOH
 3.599
 CD1
 O
ILE D:242 D:252 21.0 0.12 H -45.0 -53.1 21.0 0.12 0.0 HOH
 5.773
 N
 O
ILE E:242 E:252 22.0 0.126 H -50.4 -43.5 22.0 0.126 0.0 HOH
 3.207
 CA
 O
ILE F:242 F:252 56.0 0.32 H -34.5 -52.5 56.0 0.32 0.0 HOH
 6.506
 CD1
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:242 A:252 23.0 0.131 H -45.8 -43.8 23.0 0.131 0.0 HOH
 5.224
 O
 O
ILE B:242 B:252 25.0 0.143 H -39.1 -50.0 25.0 0.143 0.0 HOH
 9.834
 C
 O
ILE C:242 C:252 24.0 0.137 H -47.2 -40.8 24.0 0.137 0.0 HOH
 7.536
 C
 O
ILE D:242 D:252 18.0 0.103 H -44.3 -39.7 18.0 0.103 0.0 HOH
 8.105
 N
 O
ILE E:242 E:252 17.0 0.097 H -53.7 -37.4 17.0 0.097 0.0 HOH
 3.442
 N
 O
ILE F:242 F:252 29.0 0.166 H -43.7 -40.9 29.0 0.166 0.0 HOH
 6.195
 CG2
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:242 A:252 20.0 0.114 H -51.5 -39.3 20.0 0.114 0.0 HOH
 3.320
 CG1
 O
ILE B:242 B:252 29.0 0.166 H -40.7 -45.3 29.0 0.166 0.0 HOH
 5.042
 O
 O
ILE C:242 C:252 22.0 0.126 H -41.2 -40.6 22.0 0.126 0.0 HOH
 4.533
 N
 O
ILE D:242 D:252 33.0 0.189 H -46.0 -38.2 33.0 0.189 0.0 HOH
 3.490
 CG2
 O
ILE E:242 E:252 22.0 0.126 H -52.6 -46.6 22.0 0.126 0.0 HOH
 3.850
 CD1
 O
ILE F:242 F:252 22.0 0.126 H -60.7 -49.5 22.0 0.126 0.0 HOH
 3.560
 CA
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ILE A:242 A:252 24.0 0.137 H -52.2 -39.3 24.0 0.137 0.0 HOH
 3.793
 N
 O
ILE B:242 B:252 23.0 0.131 H -43.4 -44.3 23.0 0.131 0.0 HOH
 3.361
 CA
 O
ILE C:242 C:252 25.0 0.143 H -50.8 -38.2 25.0 0.143 0.0 HOH
 4.019
 N
 O
ILE D:242 D:252 22.0 0.126 H -39.8 -40.1 22.0 0.126 0.0
ILE E:242 E:252 18.0 0.103 H -53.8 -39.5 18.0 0.103 0.0 HOH
 3.295
 CA
 O
ILE F:242 F:252 31.0 0.177 H -32.2 -46.5 31.0 0.177 0.0 HOH
 4.668
 N
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 ILE A:242 A:252 19.0 0.109 H -50.5 -38.9 19.0 0.109 0.0
ILE B:242 B:252 22.0 0.126 H -61.2 -30.0 22.0 0.126 0.0 HOH
 7.481
 O
 O
ILE C:242 C:252 24.0 0.137 H -51.4 -41.0 24.0 0.137 0.0
ILE D:242 D:252 23.0 0.131 H -58.2 -27.5 23.0 0.131 0.0
ILE E:242 E:252 21.0 0.12 H -67.3 -39.7 21.0 0.12 0.0 HOH
 8.094
 CG2
 O
ILE F:242 F:252 25.0 0.143 H -46.9 -34.9 25.0 0.143 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 ILE A:252 A:252 20.0 0.114 H -60.6 -35.9