Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 11687838 | . | T | A | CCDS5985.1:NM_004462.3:c.788aTa>aAa_NP_004453.3:p.263I>K | Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3asx | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2011-12-21 | ILE | A:233 | A:263 | 0.0 | 0.0 | H | -61.3 | -36.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.034 |
C |
O |
||
| 3lee | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2010-12-08 | ILE | A:233 | A:263 | 0.0 | 0.0 | H | -55.9 | -44.8 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | B:233 | B:263 | 0.0 | 0.0 | H | -69.3 | -43.2 | NA | NA | NA | |||||||||||||
| ILE | C:233 | C:263 | 0.0 | 0.0 | H | -42.8 | -50.2 | NA | NA | NA | |||||||||||||
| ILE | D:233 | D:263 | 0.0 | 0.0 | H | -61.6 | -34.3 | NA | NA | NA | |||||||||||||
| ILE | E:233 | E:263 | 0.0 | 0.0 | H | -54.8 | -50.6 | NA | NA | NA | |||||||||||||
| ILE | F:233 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3q2z | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2011-12-21 | ILE | A:233 | A:263 | 0.0 | 0.0 | H | -60.9 | -40.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.025 |
C |
O |
||
| 3q30 | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2011-12-21 | ILE | A:233 | A:263 | 0.0 | 0.0 | H | -52.8 | -46.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.068 |
C |
O |
||
| 3v66 | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-12-19 | ILE | A:233 | A:263 | 0.0 | 0.0 | H | -59.0 | -40.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.980 |
C |
O |
||
| 3vj8 | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-04-11 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -61.3 | -41.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.043 |
C |
O |
||
| 3vj9 | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-04-11 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -62.9 | -38.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.090 |
C |
O |
||
| 3vja | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-04-11 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -60.6 | -45.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.011 |
C |
O |
||
| ILE | B:236 | B:263 | 0.0 | 0.0 | H | -62.7 | -41.9 | NA | NA | NA | |||||||||||||
| 3vjb | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-04-11 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -56.4 | -45.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.893 |
C |
O |
||
| ILE | B:236 | B:263 | 0.0 | 0.0 | H | -58.3 | -44.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.912 |
C |
O |
|||||||||
| ILE | C:236 | C:263 | 0.0 | 0.0 | H | -59.0 | -44.4 | 0.0 | 0.0 | 0.0 |
HOH |
7.406 |
CB |
O |
|||||||||
| ILE | D:236 | D:263 | 0.0 | 0.0 | H | -65.5 | -39.1 | NA | NA | NA | |||||||||||||
| ILE | E:236 | E:263 | 0.0 | 0.0 | H | -58.7 | -43.3 | NA | NA | NA | |||||||||||||
| ILE | F:236 | F:263 | 0.0 | 0.0 | H | -55.7 | -50.3 | NA | NA | NA | |||||||||||||
| 3vjc | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-04-11 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -59.8 | -42.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.994 |
C |
O |
||
| ILE | B:236 | B:263 | 0.0 | 0.0 | H | -56.0 | -43.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.961 |
C |
O |
|||||||||
| ILE | C:236 | C:263 | 0.0 | 0.0 | H | -63.0 | -41.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.993 |
C |
O |
|||||||||
| ILE | D:236 | D:263 | 0.0 | 0.0 | H | -64.1 | -43.9 | NA | NA | NA | |||||||||||||
| ILE | E:236 | E:263 | 0.0 | 0.0 | H | -63.7 | -43.4 | NA | NA | NA | |||||||||||||
| ILE | F:236 | F:263 | 0.0 | 0.0 | H | -58.2 | -45.1 | NA | NA | NA | |||||||||||||
| 3wef | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2014-02-12 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -64.2 | -44.6 | 0.0 | 0.0 | 0.0 |
HOH |
7.459 |
CB |
O |
||
| ILE | B:236 | B:263 | 0.0 | 0.0 | H | -59.0 | -41.9 | 0.0 | 0.0 | 0.0 |
HOH |
7.502 |
O |
O |
|||||||||
| ILE | C:236 | C:263 | 0.0 | 0.0 | H | -50.9 | -46.8 | 0.0 | 0.0 | 0.0 |
HOH |
7.228 |
CB |
O |
|||||||||
| ILE | D:236 | D:263 | 0.0 | 0.0 | H | -60.8 | -41.6 | NA | NA | NA | |||||||||||||
| ILE | E:236 | E:263 | 0.0 | 0.0 | H | -63.0 | -43.0 | NA | NA | NA | |||||||||||||
| ILE | F:236 | F:263 | 0.0 | 0.0 | H | -52.9 | -51.4 | NA | NA | NA | |||||||||||||
| 3weg | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2014-02-12 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -60.0 | -43.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.065 |
C |
O |
||
| 3weh | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2014-02-12 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -62.4 | -42.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.056 |
C |
O |
||
| 3wek | 1 | P37268 | 99.71 | 0.0 |
X-RAY |
2014-02-12 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -48.1 | -48.1 | 0.0 | 0.0 | 0.0 |
HOH |
6.147 |
C |
O |
||
| 3wei | 1 | P37268 | 99.71 | 0.0 |
X-RAY |
2014-02-12 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -55.1 | -42.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.021 |
C |
O |
||
| 3wej | 1 | P37268 | 99.71 | 0.0 |
X-RAY |
2014-02-12 | ILE | A:236 | A:263 | 0.0 | 0.0 | H | -55.6 | -42.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.779 |
C |
O |
||
| 1ezf | 1 | P37268 | 99.12 | 0.0 |
X-RAY |
2000-10-18 | ILE | A:233 | A:263 | 0.0 | 0.0 | H | -64.0 | -42.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.964 |
C |
O |
||
| ILE | B:233 | B:263 | 0.0 | 0.0 | H | -62.5 | -42.9 | NA | NA | NA | |||||||||||||
| ILE | C:233 | C:263 | 0.0 | 0.0 | H | -62.5 | -40.8 | NA | NA | NA | |||||||||||||
| 3wc9 | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | ILE | A:253 | A:263 | 0.0 | 0.0 | H | -56.2 | -40.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.457 |
C |
O |
||
| ILE | B:253 | B:263 | 0.0 | 0.0 | H | -58.1 | -42.1 | 0.0 | 0.0 | 0.0 |
HOH |
6.353 |
C |
O |
|||||||||
| ILE | C:253 | C:263 | 0.0 | 0.0 | H | -56.2 | -40.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.267 |
C |
O |
|||||||||
| ILE | D:253 | D:263 | 0.0 | 0.0 | H | -50.5 | -29.6 | 0.0 | 0.0 | 0.0 |
HOH |
8.037 |
C |
O |
|||||||||
| ILE | E:253 | E:263 | 0.0 | 0.0 | H | -59.2 | -43.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.670 |
O |
O |
|||||||||
| ILE | F:253 | F:263 | 0.0 | 0.0 | H | -81.6 | -41.1 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 3wcd | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | ILE | A:253 | A:263 | 0.0 | 0.0 | H | -66.1 | -40.1 | 0.0 | 0.0 | 0.0 |
HOH |
7.110 |
CB |
O |
||
| ILE | B:253 | B:263 | 0.0 | 0.0 | H | -54.2 | -39.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.980 |
O |
O |
|||||||||
| ILE | C:253 | C:263 | 0.0 | 0.0 | H | -64.7 | -45.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.630 |
N |
O |
|||||||||
| ILE | D:253 | D:263 | 0.0 | 0.0 | H | -45.8 | -43.3 | 0.0 | 0.0 | 0.0 |
HOH |
8.456 |
O |
O |
|||||||||
| ILE | E:253 | E:263 | 0.0 | 0.0 | H | -59.5 | -40.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.713 |
N |
O |
|||||||||
| ILE | F:253 | F:263 | 0.0 | 0.0 | H | -52.8 | -52.1 | 0.0 | 0.0 | 0.0 |
HOH |
6.668 |
O |
O |
|||||||||
| 3wcf | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | ILE | A:253 | A:263 | 0.0 | 0.0 | H | -60.7 | -44.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.936 |
C |
O |
||
| ILE | B:253 | B:263 | 0.0 | 0.0 | H | -58.9 | -42.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.470 |
O |
O |
|||||||||
| ILE | C:253 | C:263 | 0.0 | 0.0 | H | -60.9 | -39.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.072 |
C |
O |
|||||||||
| ILE | D:253 | D:263 | 0.0 | 0.0 | H | -63.1 | -39.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.929 |
N |
O |
|||||||||
| ILE | E:253 | E:263 | 0.0 | 0.0 | H | -63.5 | -46.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.058 |
N |
O |
|||||||||
| ILE | F:253 | F:263 | 0.0 | 0.0 | H | -59.3 | -40.8 | 0.0 | 0.0 | 0.0 |
HOH |
8.233 |
O |
O |
|||||||||
| 3wch | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | ILE | A:253 | A:263 | 0.0 | 0.0 | H | -66.7 | -42.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.136 |
C |
O |
||
| ILE | B:253 | B:263 | 0.0 | 0.0 | H | -63.2 | -38.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.470 |
O |
O |
|||||||||
| ILE | C:253 | C:263 | 0.0 | 0.0 | H | -63.3 | -33.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.184 |
C |
O |
|||||||||
| ILE | D:253 | D:263 | 0.0 | 0.0 | H | -51.1 | -41.9 | 0.0 | 0.0 | 0.0 | |||||||||||||
| ILE | E:253 | E:263 | 0.0 | 0.0 | H | -61.9 | -41.1 | 0.0 | 0.0 | 0.0 |
HOH |
6.448 |
N |
O |
|||||||||
| ILE | F:253 | F:263 | 0.0 | 0.0 | H | -65.2 | -42.0 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 3wci | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | ILE | A:253 | A:263 | 0.0 | 0.0 | H | -63.8 | -39.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.000 |
C |
O |
||
| ILE | B:253 | B:263 | 0.0 | 0.0 | H | -55.4 | -41.1 | 0.0 | 0.0 | 0.0 |
HOH |
6.182 |
C |
O |
|||||||||
| ILE | C:253 | C:263 | 0.0 | 0.0 | H | -65.4 | -37.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.917 |
N |
O |
|||||||||
| ILE | D:253 | D:263 | 0.0 | 0.0 | H | -56.2 | -39.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.746 |
CB |
O |
|||||||||
| ILE | E:253 | E:263 | 0.0 | 0.0 | H | -61.5 | -41.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.060 |
C |
O |
|||||||||
| ILE | F:253 | F:263 | 0.0 | 0.0 | H | -53.4 | -47.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.620 |
O |
O |
|||||||||
| 3wcj | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | ILE | A:253 | A:263 | 0.0 | 0.0 | H | -62.8 | -41.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.999 |
C |
O |
||
| ILE | B:253 | B:263 | 0.0 | 0.0 | H | -57.2 | -41.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.834 |
C |
O |
|||||||||
| ILE | C:253 | C:263 | 0.0 | 0.0 | H | -62.2 | -43.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.599 |
C |
O |
|||||||||
| ILE | D:253 | D:263 | 0.0 | 0.0 | H | -59.1 | -39.8 | 0.0 | 0.0 | 0.0 |
HOH |
9.313 |
O |
O |
|||||||||
| ILE | E:253 | E:263 | 0.0 | 0.0 | H | -64.2 | -44.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.899 |
N |
O |
|||||||||
| ILE | F:253 | F:263 | 0.0 | 0.0 | H | -54.2 | -48.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.402 |
O |
O |
|||||||||
| 3wcl | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | ILE | A:253 | A:263 | 0.0 | 0.0 | H | -66.6 | -40.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.820 |
C |
O |
||
| ILE | B:253 | B:263 | 0.0 | 0.0 | H | -58.6 | -40.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.903 |
C |
O |
|||||||||
| ILE | C:253 | C:263 | 0.0 | 0.0 | H | -61.5 | -42.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.873 |
N |
O |
|||||||||
| ILE | D:253 | D:263 | 0.0 | 0.0 | H | -56.7 | -49.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.915 |
C |
O |
|||||||||
| ILE | E:253 | E:263 | 0.0 | 0.0 | H | -61.8 | -45.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.101 |
N |
O |
|||||||||
| ILE | F:253 | F:263 | 0.0 | 0.0 | H | -56.8 | -46.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.932 |
C |
O |
|||||||||
| 3wcm | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | ILE | A:253 | A:263 | 0.0 | 0.0 | H | -62.2 | -41.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.971 |
C |
O |
||
| ILE | B:253 | B:263 | 0.0 | 0.0 | H | -58.3 | -42.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.273 |
C |
O |
|||||||||
| ILE | C:253 | C:263 | 0.0 | 0.0 | H | -62.2 | -42.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.102 |
C |
O |
|||||||||
| ILE | D:253 | D:263 | 1.0 | 0.006 | H | -60.0 | -39.1 | 1.0 | 0.006 | 0.0 |
HOH |
6.668 |
C |
O |
|||||||||
| ILE | E:253 | E:263 | 0.0 | 0.0 | H | -67.5 | -41.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.975 |
C |
O |
|||||||||
| ILE | F:253 | F:263 | 0.0 | 0.0 | H | -60.1 | -37.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.771 |
C |
O |
|||||||||
| 3wsa | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2015-04-01 | ILE | A:253 | A:263 | 0.0 | 0.0 | H | -64.9 | -42.1 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | B:253 | B:263 | 0.0 | 0.0 | H | -61.5 | -39.6 | 0.0 | 0.0 | 0.0 | |||||||||||||
| ILE | C:253 | C:263 | 0.0 | 0.0 | H | -61.0 | -42.3 | 0.0 | 0.0 | 0.0 |
HOH |
7.395 |
O |
O |
|||||||||
| ILE | D:253 | D:263 | 0.0 | 0.0 | H | -53.4 | -38.1 | 0.0 | 0.0 | 0.0 | |||||||||||||
| ILE | E:253 | E:263 | 0.0 | 0.0 | H | -72.9 | -35.7 | 0.0 | 0.0 | 0.0 | |||||||||||||
| ILE | F:253 | F:263 | 0.0 | 0.0 | H | -57.1 | -38.9 | 0.0 | 0.0 | 0.0 | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p37268-f1 | 1 | P37268 | 100.0 | 0.0 | ILE | A:263 | A:263 | 0.0 | 0.0 | H | -64.3 | -41.2 | |