Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11687916 . G A CCDS5985.1:NM_004462.3:c.866tGt>tAt_NP_004453.3:p.289C>Y Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 CYS A:259 A:289 10.0 0.074 H -80.2 -36.2 10.0 0.074 0.0 D99
HOH
 3.794
2.744
 CA
O
 C12
O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 CYS A:259 A:289 10.0 0.074 H -91.6 -52.9 10.0 0.074 0.0 B65
HOH
 9.406
6.453
 N
N
 CAH
O
CYS B:259 B:289 10.0 0.074 H -80.3 -35.8 NA NA NA
CYS C:259 C:289 10.0 0.074 H -84.5 -34.7 NA NA NA
CYS D:259 D:289 9.0 0.067 H -78.6 -49.0 NA NA NA
CYS E:259 E:289 5.0 0.037 H -81.1 -48.7 NA NA NA
CYS F:259 F:289 9.0 0.067 H -82.4 -48.8 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 CYS A:259 A:289 11.0 0.081 H -79.9 -30.2 11.0 0.081 0.0 D9A
HOH
 3.851
2.972
 CA
O
 C14
O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 CYS A:259 A:289 9.0 0.067 H -86.8 -43.1 9.0 0.067 0.0 D61
HOH
 3.715
2.699
 SG
O
 C1
O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 CYS A:259 A:289 11.0 0.081 H -74.7 -37.5 11.0 0.081 0.0 D3A
HOH
 3.832
2.701
 SG
O
 C19
O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 CYS A:262 A:289 9.0 0.067 H -79.4 -35.4 9.0 0.067 0.0 HOH
 6.788
 N
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 CYS A:262 A:289 10.0 0.074 H -79.3 -36.2 10.0 0.074 0.0 HOH
 2.743
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 CYS A:262 A:289 9.0 0.067 H -77.2 -39.0 9.0 0.067 0.0 HOH
 3.863
 CA
 O
CYS B:262 B:289 9.0 0.067 H -79.4 -36.3 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 CYS A:262 A:289 10.0 0.074 H -77.5 -40.7 10.0 0.074 0.0 HOH
 2.770
 O
 O
CYS B:262 B:289 11.0 0.081 H -81.4 -39.6 11.0 0.081 0.0 HOH
 6.686
 N
 O
CYS C:262 C:289 9.0 0.067 H -84.6 -35.2 9.0 0.067 0.0 HOH
 6.410
 N
 O
CYS D:262 D:289 8.0 0.059 H -79.1 -37.9 NA NA NA
CYS E:262 E:289 9.0 0.067 H -78.7 -41.2 NA NA NA
CYS F:262 F:289 10.0 0.074 H -78.5 -42.6 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 CYS A:262 A:289 10.0 0.074 H -80.8 -41.1 10.0 0.074 0.0 ZGA
HOH
 8.477
2.763
 O
O
 CAD
O
CYS B:262 B:289 10.0 0.074 H -85.2 -37.9 10.0 0.074 0.0 ZGA
HOH
 8.076
6.671
 O
N
 CAD
O
CYS C:262 C:289 9.0 0.067 H -81.6 -41.0 9.0 0.067 0.0 ZGA
HOH
 7.865
2.736
 O
O
 CAD
O
CYS D:262 D:289 9.0 0.067 H -79.7 -38.9 NA NA NA
CYS E:262 E:289 9.0 0.067 H -84.1 -40.1 NA NA NA
CYS F:262 F:289 10.0 0.074 H -80.9 -38.5 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 CYS A:262 A:289 10.0 0.074 H -78.4 -44.0 10.0 0.074 0.0 FPS
FPS
HOH
 3.130
8.731
2.875
 SG
N
O
 C14
C14
O
CYS B:262 B:289 10.0 0.074 H -82.9 -37.3 10.0 0.074 0.0 FPS
FPS
HOH
 3.204
8.544
2.817
 SG
N
O
 C14
C14
O
CYS C:262 C:289 11.0 0.081 H -78.2 -37.7 11.0 0.081 0.0 FPS
HOH
 3.247
2.906
 SG
O
 C14
O
CYS D:262 D:289 9.0 0.067 H -78.8 -43.6 NA NA NA
CYS E:262 E:289 10.0 0.074 H -69.4 -41.7 NA NA NA
CYS F:262 F:289 12.0 0.089 H -84.1 -33.7 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 CYS A:262 A:289 9.0 0.067 H -80.8 -40.7 9.0 0.067 0.0 FPS
FPS
HOH
 3.731
8.800
2.722
 SG
N
O
 C14
C15
O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 CYS A:262 A:289 9.0 0.067 H -80.8 -42.5 9.0 0.067 0.0 PS7
HOH
 3.764
2.670
 SG
O
 CAD
O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 CYS A:262 A:289 11.0 0.081 H -73.0 -41.7 11.0 0.081 0.0 PS7
HOH
 3.655
2.738
 SG
O
 CAD
O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 CYS A:262 A:289 9.0 0.067 H -74.2 -40.0 9.0 0.067 0.0 PS7
HOH
 3.796
2.765
 SG
O
 CAD
O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 CYS A:262 A:289 13.0 0.096 H -79.8 -38.2 13.0 0.096 0.0 PS7
HOH
 3.740
2.794
 SG
O
 CAD
O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 CYS A:259 A:289 13.0 0.096 H -78.5 -41.3 13.0 0.096 0.0 IN0
HOH
 3.904
2.766
 CA
O
 C27
O
CYS B:259 B:289 10.0 0.074 H -82.9 -41.9 NA NA NA
CYS C:259 C:289 10.0 0.074 H -80.4 -41.1 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 CYS A:279 A:289 9.0 0.067 H -91.1 -41.3 9.0 0.067 0.0 FPS
HOH
 3.792
2.734
 SG
O
 C14
O
CYS B:279 B:289 10.0 0.074 H -87.7 -51.3 10.0 0.074 0.0 FPS
HOH
 3.970
4.001
 SG
CA
 C14
O
CYS C:279 C:289 9.0 0.067 H -83.7 -36.8 9.0 0.067 0.0 FPS
HOH
 3.852
7.630
 SG
N
 C14
O
CYS D:279 D:289 8.0 0.059 H -99.2 -51.4 8.0 0.059 0.0 FPS
FPS
HOH
 3.704
8.758
3.020
 SG
SG
O
 C14
C15
O
CYS E:279 E:289 8.0 0.059 H -91.6 -55.7 8.0 0.059 0.0 FPS
HOH
 3.894
7.240
 SG
O
 C14
O
CYS F:279 F:289 11.0 0.081 H -88.7 -44.2 11.0 0.081 0.0 FPS
HOH
 3.857
6.626
 SG
N
 C14
O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 CYS A:279 A:289 10.0 0.074 H -84.7 -49.6 10.0 0.074 0.0 RWY
HOH
 2.960
6.444
 CA
N
 CAC
O
CYS B:279 B:289 13.0 0.096 H -86.0 -45.1 13.0 0.096 0.0 RWY
HOH
 2.837
7.367
 O
N
 CAC
O
CYS C:279 C:289 10.0 0.074 H -83.4 -41.5 10.0 0.074 0.0 HOH
 4.830
 SG
 O
CYS D:279 D:289 11.0 0.081 H -88.7 -46.1 11.0 0.081 0.0 RWY
HOH
 3.150
8.527
 CA
O
 CAC
O
CYS E:279 E:289 13.0 0.096 H -92.3 -46.1 13.0 0.096 0.0 RWY
HOH
 2.557
6.757
 O
N
 CAC
O
CYS F:279 F:289 10.0 0.074 H -78.5 -49.0 10.0 0.074 0.0 HOH
 4.150
 SG
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 CYS A:279 A:289 10.0 0.074 H -78.1 -39.4 10.0 0.074 0.0 BH8
HOH
 3.921
2.757
 SG
O
 CAA
O
CYS B:279 B:289 9.0 0.067 H -81.5 -43.6 9.0 0.067 0.0 BH8
HOH
 3.609
2.651
 SG
O
 CAA
O
CYS C:279 C:289 10.0 0.074 H -78.2 -42.4 10.0 0.074 0.0 BH8
HOH
 3.150
2.673
 SG
O
 CAA
O
CYS D:279 D:289 11.0 0.081 H -83.5 -44.4 11.0 0.081 0.0 BH8
HOH
 4.063
2.789
 SG
O
 CAK
O
CYS E:279 E:289 9.0 0.067 H -82.2 -44.5 9.0 0.067 0.0 BH8
HOH
 3.662
2.602
 SG
O
 CAA
O
CYS F:279 F:289 11.0 0.081 H -82.9 -44.2 11.0 0.081 0.0 BH8
HOH
 4.279
2.882
 SG
O
 CAK
O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 CYS A:279 A:289 10.0 0.074 H -86.0 -36.6 10.0 0.074 0.0 8PH
8PH
HOH
 3.393
7.632
2.954
 SG
O
O
 CAA
CAQ
O
CYS B:279 B:289 10.0 0.074 H -83.0 -38.6 10.0 0.074 0.0 8PH
8PH
HOH
 3.734
7.388
2.723
 SG
O
O
 CAA
CAP
O
CYS C:279 C:289 11.0 0.081 H -86.5 -34.9 11.0 0.081 0.0 8PH
HOH
 4.067
2.916
 SG
O
 CAA
O
CYS D:279 D:289 10.0 0.074 H -81.1 -48.9 10.0 0.074 0.0 8PH
HOH
 3.194
2.712
 SG
O
 CAA
O
CYS E:279 E:289 9.0 0.067 H -86.9 -45.4 9.0 0.067 0.0 8PH
HOH
 3.815
2.778
 SG
O
 CAA
O
CYS F:279 F:289 10.0 0.074 H -88.1 -37.1 10.0 0.074 0.0 8PH
8PH
HOH
 3.499
7.662
6.964
 SG
O
N
 CAA
CAP
O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 CYS A:279 A:289 10.0 0.074 H -80.9 -37.6 10.0 0.074 0.0 BH5
HOH
 3.480
2.820
 SG
O
 CAA
O
CYS B:279 B:289 10.0 0.074 H -80.5 -40.5 10.0 0.074 0.0 BH5
HOH
 3.541
2.743
 SG
O
 CAA
O
CYS C:279 C:289 10.0 0.074 H -79.3 -38.3 10.0 0.074 0.0 BH5
HOH
 3.601
2.947
 SG
O
 CAA
O
CYS D:279 D:289 10.0 0.074 H -81.9 -41.1 10.0 0.074 0.0 BH5
HOH
 3.350
2.834
 SG
O
 CAA
O
CYS E:279 E:289 10.0 0.074 H -86.3 -40.7 10.0 0.074 0.0 BH5
HOH
 3.545
2.850
 SG
O
 CAA
O
CYS F:279 F:289 12.0 0.089 H -80.0 -41.0 12.0 0.089 0.0 BH5
HOH
 3.260
2.693
 SG
O
 CAA
O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 CYS A:279 A:289 10.0 0.074 H -82.1 -43.4 10.0 0.074 0.0 E5S
HOH
 3.301
7.342
 O
SG
 OAB
O
CYS B:279 B:289 9.0 0.067 H -77.8 -42.3 9.0 0.067 0.0 E5S
HOH
 3.016
6.259
 O
N
 OAB
O
CYS C:279 C:289 9.0 0.067 H -78.0 -38.6 9.0 0.067 0.0 E5S
HOH
 3.331
6.478
 O
N
 OAB
O
CYS D:279 D:289 9.0 0.067 H -82.0 -48.7 9.0 0.067 0.0 E5S
HOH
 3.429
6.246
 O
N
 OAB
O
CYS E:279 E:289 8.0 0.059 H -82.0 -57.3 8.0 0.059 0.0 E5S
HOH
 3.303
6.279
 O
N
 OAB
O
CYS F:279 F:289 10.0 0.074 H -76.3 -41.6 10.0 0.074 0.0 E5S
HOH
 3.210
6.341
 O
N
 OAB
O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 CYS A:279 A:289 11.0 0.081 H -82.6 -43.4 11.0 0.081 0.0 BH3
HOH
 3.436
2.739
 SG
O
 CAA
O
CYS B:279 B:289 11.0 0.081 H -78.9 -38.6 11.0 0.081 0.0 HOH
 2.754
 O
 O
CYS C:279 C:289 11.0 0.081 H -79.2 -43.2 11.0 0.081 0.0 HOH
 2.970
 O
 O
CYS D:279 D:289 10.0 0.074 H -78.3 -44.9 10.0 0.074 0.0 HOH
 2.819
 O
 O
CYS E:279 E:289 8.0 0.059 H -83.6 -39.8 8.0 0.059 0.0 HOH
 2.838
 O
 O
CYS F:279 F:289 11.0 0.081 H -78.6 -41.3 11.0 0.081 0.0 HOH
 2.762
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 CYS A:279 A:289 11.0 0.081 H -83.9 -44.4 11.0 0.081 0.0 ER4
HOH
 3.730
2.699
 SG
O
 CAA
O
CYS B:279 B:289 10.0 0.074 H -80.5 -39.8 10.0 0.074 0.0 ER4
HOH
 3.722
2.676
 SG
O
 CAA
O
CYS C:279 C:289 11.0 0.081 H -83.5 -43.1 11.0 0.081 0.0 ER4
HOH
 3.860
2.845
 SG
O
 CAA
O
CYS D:279 D:289 9.0 0.067 H -85.2 -43.8 9.0 0.067 0.0 ER4
HOH
 3.997
2.819
 SG
O
 CAA
O
CYS E:279 E:289 9.0 0.067 H -86.8 -46.7 9.0 0.067 0.0 ER4
HOH
 3.927
2.836
 SG
O
 CAA
O
CYS F:279 F:289 12.0 0.089 H -80.8 -44.6 12.0 0.089 0.0 ER4
HOH
 4.135
2.806
 SG
O
 CAA
O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 CYS A:279 A:289 11.0 0.081 H -96.1 -37.3 11.0 0.081 0.0 RWZ
HOH
 3.621
9.779
 SG
N
 CAB
O
CYS B:279 B:289 11.0 0.081 H -97.6 -34.1 11.0 0.081 0.0 RWZ
HOH
 3.733
9.842
 SG
SG
 CAB
O
CYS C:279 C:289 11.0 0.081 H -86.9 -42.4 11.0 0.081 0.0 RWZ
HOH
 3.589
7.747
 SG
N
 CAB
O
CYS D:279 D:289 12.0 0.089 H -96.4 -49.8 12.0 0.089 0.0 HOH
 4.620
 CA
 O
CYS E:279 E:289 11.0 0.081 H -96.1 -40.2 11.0 0.081 0.0 RWZ
 3.633
 SG
 CAB
CYS F:279 F:289 12.0 0.089 H -96.7 -36.7 12.0 0.089 0.0 HOH
 4.430
 SG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 CYS A:289 A:289 10.0 0.074 H -77.3 -41.1