Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11687919 . C A CCDS5985.1:NM_004462.3:c.869gCt>gAt_NP_004453.3:p.290A>D Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:260 A:290 0.0 0.0 H -78.7 -34.5 0.0 0.0 0.0 D99
HOH
 5.987
4.876
 N
N
 C12
O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 ALA A:260 A:290 0.0 0.0 H -52.6 -60.0 0.0 0.0 0.0 HOH
 8.485
 N
 O
ALA B:260 B:290 0.0 0.0 H -72.8 -47.2 NA NA NA
ALA C:260 C:290 0.0 0.0 H -80.3 -52.9 NA NA NA
ALA D:260 D:290 0.0 0.0 H -59.6 -58.0 NA NA NA
ALA E:260 E:290 0.0 0.0 H -68.5 -36.5 NA NA NA
ALA F:260 F:290 0.0 0.0 H -70.2 -43.4 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:260 A:290 0.0 0.0 H -80.1 -33.7 0.0 0.0 0.0 D9A
HOH
 5.947
5.112
 N
N
 C14
O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:260 A:290 0.0 0.0 H -68.8 -31.8 0.0 0.0 0.0 D61
HOH
 6.059
4.922
 N
N
 C2
O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 ALA A:260 A:290 0.0 0.0 H -77.3 -37.8 0.0 0.0 0.0 D3A
HOH
 5.888
4.882
 N
N
 C18
O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:263 A:290 0.0 0.0 H -78.7 -35.4 0.0 0.0 0.0 HOH
 7.522
 O
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:263 A:290 0.0 0.0 H -76.6 -38.4 0.0 0.0 0.0 HOH
 4.879
 N
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:263 A:290 0.0 0.0 H -78.3 -38.8 0.0 0.0 0.0 HOH
 5.602
 N
 O
ALA B:263 B:290 0.0 0.0 H -75.1 -36.2 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:263 A:290 0.0 0.0 H -74.8 -42.4 0.0 0.0 0.0 HOH
 4.899
 N
 O
ALA B:263 B:290 0.0 0.0 H -74.7 -40.2 0.0 0.0 0.0 HOH
 7.545
 O
 O
ALA C:263 C:290 0.0 0.0 H -81.1 -41.2 0.0 0.0 0.0 HOH
 7.416
 O
 O
ALA D:263 D:290 0.0 0.0 H -80.6 -40.4 NA NA NA
ALA E:263 E:290 0.0 0.0 H -77.5 -37.3 NA NA NA
ALA F:263 F:290 0.0 0.0 H -77.4 -38.7 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:263 A:290 0.0 0.0 H -78.0 -37.9 0.0 0.0 0.0 ZGA
HOH
 8.032
4.865
 O
N
 CBB
O
ALA B:263 B:290 0.0 0.0 H -79.9 -39.4 0.0 0.0 0.0 ZGA
HOH
 8.050
8.043
 O
CB
 CAD
O
ALA C:263 C:290 0.0 0.0 H -74.6 -42.6 0.0 0.0 0.0 ZGA
HOH
 8.247
4.885
 O
N
 CAD
O
ALA D:263 D:290 0.0 0.0 H -82.0 -38.0 NA NA NA
ALA E:263 E:290 0.0 0.0 H -77.4 -40.8 NA NA NA
ALA F:263 F:290 0.0 0.0 H -78.6 -42.0 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:263 A:290 0.0 0.0 H -72.5 -42.3 0.0 0.0 0.0 FPS
HOH
 6.377
5.040
 N
N
 C14
O
ALA B:263 B:290 0.0 0.0 H -73.8 -45.4 0.0 0.0 0.0 FPS
HOH
 6.012
4.945
 N
N
 C14
O
ALA C:263 C:290 0.0 0.0 H -73.9 -46.2 0.0 0.0 0.0 FPS
HOH
 6.156
5.020
 N
N
 C14
O
ALA D:263 D:290 0.0 0.0 H -80.5 -32.1 NA NA NA
ALA E:263 E:290 0.0 0.0 H -70.7 -45.4 NA NA NA
ALA F:263 F:290 0.0 0.0 H -74.7 -48.2 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:263 A:290 0.0 0.0 H -70.0 -41.4 0.0 0.0 0.0 FPS
HOH
 6.650
4.202
 N
CB
 C14
O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:263 A:290 0.0 0.0 H -75.6 -37.1 0.0 0.0 0.0 PS7
HOH
 6.712
4.799
 N
N
 CAD
O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:263 A:290 0.0 0.0 H -71.9 -41.0 0.0 0.0 0.0 PS7
HOH
 6.387
4.333
 N
CB
 CAD
O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:263 A:290 0.0 0.0 H -75.1 -39.7 0.0 0.0 0.0 PS7
HOH
 6.715
4.203
 N
CB
 CAD
O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:263 A:290 0.0 0.0 H -79.4 -38.4 0.0 0.0 0.0 PS7
HOH
 6.605
4.938
 N
N
 CAD
O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 ALA A:260 A:290 0.0 0.0 H -66.0 -37.1 0.0 0.0 0.0 IN0
HOH
 6.080
4.936
 N
N
 C27
O
ALA B:260 B:290 0.0 0.0 H -68.2 -47.3 NA NA NA
ALA C:260 C:290 0.0 0.0 H -65.4 -47.8 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:280 A:290 0.0 0.0 H -64.9 -59.6 0.0 0.0 0.0 FPS
HOH
 6.233
4.887
 N
N
 C14
O
ALA B:280 B:290 0.0 0.0 H -63.2 -56.8 0.0 0.0 0.0 FPS
HOH
 6.971
5.956
 N
N
 C14
O
ALA C:280 C:290 0.0 0.0 H -70.7 -54.2 0.0 0.0 0.0 FPS
HOH
 6.502
8.460
 N
CB
 C14
O
ALA D:280 D:290 0.0 0.0 H -62.6 -43.9 0.0 0.0 0.0 FPS
HOH
 6.902
5.103
 N
N
 C14
O
ALA E:280 E:290 0.0 0.0 H -60.0 -50.3 0.0 0.0 0.0 FPS
HOH
 6.657
7.516
 N
O
 C14
O
ALA F:280 F:290 0.0 0.0 H -64.3 -55.5 0.0 0.0 0.0 FPS
HOH
 6.468
8.132
 N
CB
 C14
O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:280 A:290 0.0 0.0 H -62.0 -45.0 0.0 0.0 0.0 RWY
HOH
 4.738
7.876
 N
CB
 CAC
O
ALA B:280 B:290 0.0 0.0 H -63.7 -54.8 0.0 0.0 0.0 RWY
HOH
 4.734
7.920
 N
O
 CAC
O
ALA C:280 C:290 0.0 0.0 H -67.1 -48.0 0.0 0.0 0.0 HOH
 7.080
 N
 O
ALA D:280 D:290 0.0 0.0 H -64.3 -42.7 0.0 0.0 0.0 RWY
HOH
 4.914
7.826
 N
CB
 CAC
O
ALA E:280 E:290 0.0 0.0 H -61.5 -51.2 0.0 0.0 0.0 RWY
HOH
 4.541
7.748
 N
O
 CAC
O
ALA F:280 F:290 0.0 0.0 H -59.2 -50.2 0.0 0.0 0.0 HOH
 6.661
 N
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:280 A:290 0.0 0.0 H -72.9 -47.6 0.0 0.0 0.0 BH8
HOH
 6.892
4.886
 N
N
 CAK
O
ALA B:280 B:290 0.0 0.0 H -69.5 -47.1 0.0 0.0 0.0 BH8
HOH
 6.667
4.759
 N
N
 CAA
O
ALA C:280 C:290 0.0 0.0 H -71.6 -44.0 0.0 0.0 0.0 BH8
HOH
 6.988
4.774
 N
N
 CAA
O
ALA D:280 D:290 0.0 0.0 H -70.7 -40.6 0.0 0.0 0.0 BH8
HOH
 7.030
4.932
 N
N
 CAK
O
ALA E:280 E:290 0.0 0.0 H -72.1 -44.1 0.0 0.0 0.0 BH8
HOH
 6.311
4.755
 N
N
 CAA
O
ALA F:280 F:290 0.0 0.0 H -65.8 -49.5 0.0 0.0 0.0 BH8
HOH
 6.769
5.000
 N
N
 CAK
O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:280 A:290 0.0 0.0 H -75.1 -41.0 0.0 0.0 0.0 8PH
8PH
HOH
 6.634
8.821
5.064
 N
C
N
 CAA
CAQ
O
ALA B:280 B:290 0.0 0.0 H -73.5 -40.3 0.0 0.0 0.0 8PH
8PH
HOH
 6.704
8.860
4.884
 N
N
N
 CAA
CAP
O
ALA C:280 C:290 0.0 0.0 H -74.2 -43.9 0.0 0.0 0.0 8PH
HOH
 7.153
4.973
 N
N
 CAL
O
ALA D:280 D:290 0.0 0.0 H -58.6 -49.8 0.0 0.0 0.0 8PH
HOH
 6.788
4.913
 N
N
 CAA
O
ALA E:280 E:290 0.0 0.0 H -65.8 -43.7 0.0 0.0 0.0 8PH
HOH
 7.199
4.864
 N
N
 CAA
O
ALA F:280 F:290 0.0 0.0 H -70.9 -49.4 0.0 0.0 0.0 8PH
8PH
HOH
 6.650
8.659
8.595
 N
C
CB
 CAA
CAR
O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:280 A:290 0.0 0.0 H -78.1 -39.1 0.0 0.0 0.0 BH5
HOH
 6.833
4.929
 N
N
 CAL
O
ALA B:280 B:290 0.0 0.0 H -68.1 -50.9 0.0 0.0 0.0 BH5
HOH
 6.677
4.887
 N
N
 CAL
O
ALA C:280 C:290 0.0 0.0 H -71.6 -45.9 0.0 0.0 0.0 BH5
HOH
 6.790
5.031
 N
N
 CAL
O
ALA D:280 D:290 0.0 0.0 H -69.2 -47.7 0.0 0.0 0.0 BH5
HOH
 6.698
5.003
 N
N
 CAL
O
ALA E:280 E:290 0.0 0.0 H -71.6 -47.6 0.0 0.0 0.0 BH5
HOH
 6.901
4.940
 N
N
 CAL
O
ALA F:280 F:290 0.0 0.0 H -67.4 -50.4 0.0 0.0 0.0 BH5
HOH
 6.623
4.823
 N
N
 CAL
O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:280 A:290 0.0 0.0 H -68.6 -46.8 0.0 0.0 0.0 E5S
HOH
 5.330
7.660
 N
O
 OAB
O
ALA B:280 B:290 0.0 0.0 H -75.3 -48.5 0.0 0.0 0.0 E5S
HOH
 5.073
8.215
 N
N
 OAB
O
ALA C:280 C:290 0.0 0.0 H -75.9 -43.5 0.0 0.0 0.0 E5S
HOH
 5.331
7.897
 N
O
 OAB
O
ALA D:280 D:290 0.0 0.0 H -68.3 -48.2 0.0 0.0 0.0 E5S
HOH
 5.459
7.579
 N
O
 OAB
O
ALA E:280 E:290 0.0 0.0 H -57.9 -50.7 0.0 0.0 0.0 E5S
HOH
 5.294
7.677
 N
O
 OAB
O
ALA F:280 F:290 0.0 0.0 H -73.9 -40.7 0.0 0.0 0.0 E5S
HOH
 5.246
7.973
 N
O
 OAB
O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:280 A:290 0.0 0.0 H -66.9 -48.9 0.0 0.0 0.0 BH3
HOH
 6.556
4.878
 N
N
 CAK
O
ALA B:280 B:290 0.0 0.0 H -71.8 -50.6 0.0 0.0 0.0 HOH
 4.868
 N
 O
ALA C:280 C:290 0.0 0.0 H -66.7 -50.0 0.0 0.0 0.0 HOH
 5.101
 N
 O
ALA D:280 D:290 0.0 0.0 H -66.7 -48.7 0.0 0.0 0.0 HOH
 4.978
 N
 O
ALA E:280 E:290 0.0 0.0 H -70.6 -48.1 0.0 0.0 0.0 HOH
 4.932
 N
 O
ALA F:280 F:290 0.0 0.0 H -72.3 -46.8 0.0 0.0 0.0 HOH
 4.894
 N
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:280 A:290 0.0 0.0 H -67.2 -47.1 0.0 0.0 0.0 ER4
HOH
 6.949
4.786
 N
N
 CAM
O
ALA B:280 B:290 0.0 0.0 H -74.7 -45.9 0.0 0.0 0.0 ER4
HOH
 7.025
4.778
 N
N
 CAM
O
ALA C:280 C:290 0.0 0.0 H -69.7 -43.4 0.0 0.0 0.0 ER4
HOH
 7.030
4.974
 N
N
 CAM
O
ALA D:280 D:290 0.0 0.0 H -70.6 -45.5 0.0 0.0 0.0 ER4
HOH
 7.113
4.927
 N
N
 CAM
O
ALA E:280 E:290 0.0 0.0 H -67.5 -44.8 0.0 0.0 0.0 ER4
HOH
 7.132
4.948
 N
N
 CAM
O
ALA F:280 F:290 0.0 0.0 H -65.7 -49.5 0.0 0.0 0.0 ER4
HOH
 6.968
4.922
 N
N
 CAM
O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 ALA A:280 A:290 0.0 0.0 H -68.1 -53.2 0.0 0.0 0.0 RWZ
HOH
 6.974
7.922
 N
CB
 CAB
O
ALA B:280 B:290 0.0 0.0 H -69.5 -62.7 0.0 0.0 0.0 RWZ
HOH
 7.089
8.619
 N
CB
 CAB
O
ALA C:280 C:290 0.0 0.0 H -62.1 -49.7 0.0 0.0 0.0 RWZ
HOH
 6.691
8.517
 N
CB
 CAB
O
ALA D:280 D:290 0.0 0.0 H -56.3 -57.3 0.0 0.0 0.0 HOH
 6.874
 N
 O
ALA E:280 E:290 0.0 0.0 H -59.6 -60.2 0.0 0.0 0.0 RWZ
HOH
 7.337
8.956
 N
CB
 CAB
O
ALA F:280 F:290 0.0 0.0 H -69.2 -49.8 0.0 0.0 0.0 HOH
 7.830
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 ALA A:290 A:290 0.0 0.0 H -72.0 -41.0