Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11689046 . T A CCDS5985.1:NM_004462.3:c.899tTg>tAg_NP_004453.3:p.300L>* Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 LEU A:270 A:300 1.0 0.006 H -59.4 -41.7 1.0 0.006 0.0 HOH
 6.351
 N
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 LEU A:270 A:300 1.0 0.006 H -67.8 -34.0 1.0 0.006 0.0
LEU B:270 B:300 1.0 0.006 H -63.2 -46.3 NA NA NA
LEU C:270 C:300 2.0 0.012 H -58.3 -41.8 NA NA NA
LEU D:270 D:300 2.0 0.012 H -60.7 -35.3 NA NA NA
LEU E:270 E:300 1.0 0.006 H -52.6 -47.4 NA NA NA
LEU F:270 F:300 38.0 0.224 H -46.8 -40.1 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 LEU A:270 A:300 1.0 0.006 H -61.7 -40.5 1.0 0.006 0.0 HOH
 6.449
 N
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 LEU A:270 A:300 1.0 0.006 H -57.9 -49.5 1.0 0.006 0.0 HOH
 6.280
 N
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 LEU A:270 A:300 1.0 0.006 H -60.4 -41.3 1.0 0.006 0.0 HOH
 6.350
 N
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 LEU A:273 A:300 1.0 0.006 H -61.0 -39.0 1.0 0.006 0.0 HOH
 6.270
 C
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 LEU A:273 A:300 1.0 0.006 H -60.7 -41.5 1.0 0.006 0.0 HOH
 5.764
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 LEU A:273 A:300 1.0 0.006 H -59.2 -41.6 1.0 0.006 0.0 HOH
 6.319
 C
 O
LEU B:273 B:300 0.0 0.0 H -65.7 -41.5 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 LEU A:273 A:300 0.0 0.0 H -56.3 -47.1 0.0 0.0 0.0 HOH
 6.725
 N
 O
LEU B:273 B:300 0.0 0.0 H -60.6 -42.8 0.0 0.0 0.0 HOH
 6.402
 C
 O
LEU C:273 C:300 1.0 0.006 H -59.2 -37.4 1.0 0.006 0.0 HOH
 8.758
 N
 O
LEU D:273 D:300 1.0 0.006 H -63.8 -41.1 NA NA NA
LEU E:273 E:300 1.0 0.006 H -57.3 -52.0 NA NA NA
LEU F:273 F:300 1.0 0.006 H -53.0 -38.2 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 LEU A:273 A:300 1.0 0.006 H -58.7 -40.1 1.0 0.006 0.0 ZGA
HOH
 6.825
6.277
 N
C
 CAB
O
LEU B:273 B:300 1.0 0.006 H -58.3 -43.1 1.0 0.006 0.0 ZGA
HOH
 6.668
6.201
 N
C
 CAB
O
LEU C:273 C:300 2.0 0.012 H -58.5 -41.3 2.0 0.012 0.0 ZGA
HOH
 7.094
6.269
 N
C
 CAX
O
LEU D:273 D:300 2.0 0.012 H -59.1 -42.6 NA NA NA
LEU E:273 E:300 1.0 0.006 H -58.3 -44.3 NA NA NA
LEU F:273 F:300 1.0 0.006 H -57.1 -40.7 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 LEU A:273 A:300 1.0 0.006 H -55.3 -44.0 1.0 0.006 0.0 HOH
 7.106
 O
 O
LEU B:273 B:300 0.0 0.0 H -55.8 -44.6 0.0 0.0 0.0
LEU C:273 C:300 1.0 0.006 H -66.6 -45.2 1.0 0.006 0.0
LEU D:273 D:300 1.0 0.006 H -54.5 -48.0 NA NA NA
LEU E:273 E:300 2.0 0.012 H -62.9 -40.7 NA NA NA
LEU F:273 F:300 1.0 0.006 H -48.6 -36.1 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 LEU A:273 A:300 0.0 0.0 H -63.2 -39.3 0.0 0.0 0.0 HOH
 6.231
 N
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 LEU A:273 A:300 1.0 0.006 H -60.5 -43.8 1.0 0.006 0.0 HOH
 6.123
 C
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 LEU A:273 A:300 0.0 0.0 H -58.8 -47.1 0.0 0.0 0.0 HOH
 6.255
 N
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 LEU A:273 A:300 0.0 0.0 H -61.2 -43.2 0.0 0.0 0.0 HOH
 6.286
 N
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 LEU A:273 A:300 1.0 0.006 H -53.3 -44.8 1.0 0.006 0.0 HOH
 6.256
 C
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 LEU A:270 A:300 1.0 0.006 H -55.8 -44.3 1.0 0.006 0.0 HOH
 6.338
 C
 O
LEU B:270 B:300 1.0 0.006 H -60.3 -47.0 NA NA NA
LEU C:270 C:300 1.0 0.006 H -63.0 -42.9 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LEU A:290 A:300 1.0 0.006 H -54.5 -46.3 1.0 0.006 0.0 HOH
 7.747
 N
 O
LEU B:290 B:300 2.0 0.012 H -59.2 -27.3 2.0 0.012 0.0 HOH
 9.828
 CD1
 O
LEU C:290 C:300 1.0 0.006 H -75.1 -35.1 1.0 0.006 0.0
LEU D:290 D:300 2.0 0.012 H -53.3 -30.8 2.0 0.012 0.0 HOH
 9.398
 N
 O
LEU E:290 E:300 1.0 0.006 H -58.4 -38.8 1.0 0.006 0.0 HOH
 8.255
 N
 O
LEU F:290 F:300 1.0 0.006 H -62.3 -22.0 1.0 0.006 0.0
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LEU A:290 A:300 1.0 0.006 H -59.8 -37.3 1.0 0.006 0.0 HOH
 7.560
 N
 O
LEU B:290 B:300 2.0 0.012 H -61.1 -38.3 2.0 0.012 0.0 HOH
 8.769
 N
 O
LEU C:290 C:300 1.0 0.006 H -67.3 -39.6 1.0 0.006 0.0 HOH
 7.273
 N
 O
LEU D:290 D:300 1.0 0.006 H -61.2 -26.4 1.0 0.006 0.0 HOH
 8.836
 N
 O
LEU E:290 E:300 2.0 0.012 H -65.8 -45.3 2.0 0.012 0.0 HOH
 8.722
 O
 O
LEU F:290 F:300 3.0 0.018 H -49.9 -47.8 3.0 0.018 0.0 HOH
 7.260
 N
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LEU A:290 A:300 1.0 0.006 H -64.0 -36.2 1.0 0.006 0.0 HOH
 6.395
 C
 O
LEU B:290 B:300 2.0 0.012 H -62.7 -43.1 2.0 0.012 0.0 HOH
 8.958
 N
 O
LEU C:290 C:300 1.0 0.006 H -66.8 -33.9 1.0 0.006 0.0 HOH
 9.153
 O
 O
LEU D:290 D:300 0.0 0.0 H -61.9 -39.2 0.0 0.0 0.0 HOH
 8.740
 N
 O
LEU E:290 E:300 1.0 0.006 H -65.1 -41.4 1.0 0.006 0.0 HOH
 9.103
 N
 O
LEU F:290 F:300 2.0 0.012 H -55.2 -40.1 2.0 0.012 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LEU A:290 A:300 0.0 0.0 H -60.5 -38.0 0.0 0.0 0.0 8PH
HOH
 9.913
9.047
 N
N
 CAS
O
LEU B:290 B:300 1.0 0.006 H -68.9 -34.8 1.0 0.006 0.0
LEU C:290 C:300 0.0 0.0 H -57.9 -40.6 0.0 0.0 0.0 HOH
 6.151
 C
 O
LEU D:290 D:300 1.0 0.006 H -50.0 -39.4 1.0 0.006 0.0
LEU E:290 E:300 2.0 0.012 H -63.7 -44.2 2.0 0.012 0.0 HOH
 8.208
 O
 O
LEU F:290 F:300 1.0 0.006 H -62.2 -37.0 1.0 0.006 0.0
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LEU A:290 A:300 1.0 0.006 H -60.5 -35.7 1.0 0.006 0.0 HOH
 6.173
 C
 O
LEU B:290 B:300 0.0 0.0 H -63.8 -37.3 0.0 0.0 0.0 HOH
 6.146
 C
 O
LEU C:290 C:300 1.0 0.006 H -61.8 -37.3 1.0 0.006 0.0 HOH
 7.682
 O
 O
LEU D:290 D:300 1.0 0.006 H -61.5 -22.8 1.0 0.006 0.0 HOH
 8.686
 N
 O
LEU E:290 E:300 2.0 0.012 H -63.6 -40.7 2.0 0.012 0.0 HOH
 6.307
 N
 O
LEU F:290 F:300 2.0 0.012 H -61.3 -32.5 2.0 0.012 0.0 HOH
 6.084
 C
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LEU A:290 A:300 1.0 0.006 H -59.7 -41.1 1.0 0.006 0.0 HOH
 7.053
 O
 O
LEU B:290 B:300 1.0 0.006 H -69.7 -40.9 1.0 0.006 0.0 HOH
 6.454
 N
 O
LEU C:290 C:300 2.0 0.012 H -63.6 -41.2 2.0 0.012 0.0 HOH
 6.189
 C
 O
LEU D:290 D:300 1.0 0.006 H -62.3 -33.5 1.0 0.006 0.0 HOH
 8.829
 N
 O
LEU E:290 E:300 1.0 0.006 H -65.6 -40.1 1.0 0.006 0.0 HOH
 6.366
 N
 O
LEU F:290 F:300 1.0 0.006 H -58.5 -39.2 1.0 0.006 0.0 HOH
 6.361
 C
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LEU A:290 A:300 0.0 0.0 H -64.2 -42.0 0.0 0.0 0.0 HOH
 6.537
 N
 O
LEU B:290 B:300 1.0 0.006 H -63.4 -38.0 1.0 0.006 0.0 HOH
 6.433
 N
 O
LEU C:290 C:300 1.0 0.006 H -62.5 -37.8 1.0 0.006 0.0 HOH
 5.675
 O
 O
LEU D:290 D:300 3.0 0.018 H -63.4 -25.6 3.0 0.018 0.0 HOH
 8.475
 N
 O
LEU E:290 E:300 2.0 0.012 H -63.5 -46.0 2.0 0.012 0.0 HOH
 7.959
 N
 O
LEU F:290 F:300 2.0 0.012 H -62.7 -36.6 2.0 0.012 0.0 HOH
 6.463
 N
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 LEU A:290 A:300 2.0 0.012 H -64.5 -40.6 2.0 0.012 0.0 HOH
 6.233
 N
 O
LEU B:290 B:300 1.0 0.006 H -65.7 -42.2 1.0 0.006 0.0 HOH
 6.205
 C
 O
LEU C:290 C:300 2.0 0.012 H -61.4 -40.5 2.0 0.012 0.0 HOH
 5.622
 O
 O
LEU D:290 D:300 2.0 0.012 H -69.2 -31.4 2.0 0.012 0.0 HOH
 6.290
 N
 O
LEU E:290 E:300 1.0 0.006 H -62.9 -40.6 1.0 0.006 0.0 HOH
 6.295
 N
 O
LEU F:290 F:300 2.0 0.012 H -64.5 -31.5 2.0 0.012 0.0 HOH
 6.208
 N
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 LEU A:290 A:300 1.0 0.006 H -65.0 -36.4 1.0 0.006 0.0 HOH
 8.076
 N
 O
LEU B:290 B:300 1.0 0.006 H -54.9 -36.0 1.0 0.006 0.0 HOH
 7.385
 O
 O
LEU C:290 C:300 2.0 0.012 H -62.1 -50.0 2.0 0.012 0.0 HOH
 9.139
 N
 O
LEU D:290 D:300 2.0 0.012 H -57.9 -36.3 2.0 0.012 0.0 HOH
 8.534
 N
 O
LEU E:290 E:300 2.0 0.012 H -61.6 -36.6 2.0 0.012 0.0
LEU F:290 F:300 1.0 0.006 H -62.0 -36.5 1.0 0.006 0.0 HOH
 7.884
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 LEU A:300 A:300 0.0 0.0 H -59.2 -40.3