Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11689051 . G A CCDS5985.1:NM_004462.3:c.904Gcc>Acc_NP_004453.3:p.302A>T Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:272 A:302 31.0 0.27 H -60.5 -36.2 31.0 0.27 0.0 HOH
 2.580
 O
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 ALA A:272 A:302 23.0 0.2 H -72.5 -21.6 23.0 0.2 0.0 HOH
 7.615
 O
 O
ALA B:272 B:302 16.0 0.139 H -65.9 -51.5 NA NA NA
ALA C:272 C:302 30.0 0.261 T -74.7 14.9 NA NA NA
ALA D:272 D:302 26.0 0.226 T -93.3 8.9 NA NA NA
ALA E:272 E:302 18.0 0.157 H -73.8 -37.2 NA NA NA
ALA F:272 F:302 78.0 0.678 H -63.2 -39.8 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:272 A:302 34.0 0.296 H -69.1 -29.5 34.0 0.296 0.0 HOH
 3.739
 CB
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:272 A:302 30.0 0.261 H -60.4 -38.2 30.0 0.261 0.0 HOH
 3.546
 CB
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 ALA A:272 A:302 29.0 0.252 H -61.8 -35.0 29.0 0.252 0.0 HOH
 2.475
 O
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:275 A:302 31.0 0.27 H -66.1 -35.9 31.0 0.27 0.0 HOH
 2.674
 O
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:275 A:302 26.0 0.226 H -67.3 -36.7 26.0 0.226 0.0 HOH
 2.768
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:275 A:302 11.0 0.096 H -66.3 -37.9 11.0 0.096 0.0 HOH
 3.040
 O
 O
ALA B:275 B:302 26.0 0.226 H -67.8 -34.0 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:275 A:302 59.0 0.513 H -75.7 -29.7 59.0 0.513 0.0 HOH
 7.697
 O
 O
ALA B:275 B:302 24.0 0.209 H -73.9 -29.7 24.0 0.209 0.0 HOH
 3.817
 CB
 O
ALA C:275 C:302 4.0 0.035 H -73.7 -26.2 4.0 0.035 0.0 HOH
 7.879
 CA
 O
ALA D:275 D:302 17.0 0.148 H -74.3 -33.0 NA NA NA
ALA E:275 E:302 20.0 0.174 H -75.3 -27.2 NA NA NA
ALA F:275 F:302 57.0 0.496 H -69.8 -28.5 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:275 A:302 6.0 0.052 H -67.2 -34.5 6.0 0.052 0.0 ZGA
HOH
 9.908
2.839
 CB
O
 CAB
O
ALA B:275 B:302 3.0 0.026 H -68.5 -31.6 3.0 0.026 0.0 ZGA
HOH
 9.798
3.188
 CB
O
 CAB
O
ALA C:275 C:302 5.0 0.043 H -66.0 -33.8 5.0 0.043 0.0 ZGA
HOH
 9.439
3.604
 CB
CB
 CAE
O
ALA D:275 D:302 4.0 0.035 H -74.5 -35.8 NA NA NA
ALA E:275 E:302 21.0 0.183 H -65.4 -33.3 NA NA NA
ALA F:275 F:302 12.0 0.104 H -68.8 -39.4 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:275 A:302 8.0 0.07 H -63.7 -33.9 8.0 0.07 0.0 HOH
 3.293
 O
 O
ALA B:275 B:302 0.0 0.0 H -70.9 -27.3 0.0 0.0 0.0
ALA C:275 C:302 10.0 0.087 H -70.5 -36.6 10.0 0.087 0.0
ALA D:275 D:302 14.0 0.122 H -73.2 -34.9 NA NA NA
ALA E:275 E:302 27.0 0.235 H -77.7 -41.3 NA NA NA
ALA F:275 F:302 32.0 0.278 H -61.8 -34.8 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:275 A:302 16.0 0.139 H -67.4 -35.5 16.0 0.139 0.0 HOH
 3.655
 CB
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:275 A:302 27.0 0.235 H -66.1 -34.5 27.0 0.235 0.0 HOH
 2.667
 O
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:275 A:302 23.0 0.2 H -74.3 -28.0 23.0 0.2 0.0 HOH
 3.630
 CB
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:275 A:302 3.0 0.026 H -68.5 -33.6 3.0 0.026 0.0 HOH
 3.684
 CB
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:275 A:302 29.0 0.252 H -63.5 -32.6 29.0 0.252 0.0 HOH
 2.686
 O
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 ALA A:272 A:302 14.0 0.122 H -75.6 -37.9 14.0 0.122 0.0 HOH
 3.105
 O
 O
ALA B:272 B:302 34.0 0.296 H -73.6 -34.7 NA NA NA
ALA C:272 C:302 42.0 0.365 H -79.4 -33.4 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:292 A:302 3.0 0.026 H -70.6 -29.9 3.0 0.026 0.0 HOH
 7.755
 CB
 O
ALA B:292 B:302 14.0 0.122 H -67.9 -20.8 14.0 0.122 0.0 HOH
 8.214
 CA
 O
ALA C:292 C:302 4.0 0.035 H -64.1 -39.4 4.0 0.035 0.0 HOH
 5.792
 O
 O
ALA D:292 D:302 8.0 0.07 H -93.8 -36.6 8.0 0.07 0.0 HOH
 8.054
 C
 O
ALA E:292 E:302 20.0 0.174 H -68.9 -41.6 20.0 0.174 0.0 HOH
 7.109
 O
 O
ALA F:292 F:302 0.0 0.0 H -92.5 -37.2 0.0 0.0 0.0 HOH
 6.618
 O
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:292 A:302 10.0 0.087 H -66.6 -30.1 10.0 0.087 0.0 HOH
 6.303
 O
 O
ALA B:292 B:302 16.0 0.139 H -55.3 -45.6 16.0 0.139 0.0 HOH
 8.901
 CB
 O
ALA C:292 C:302 2.0 0.017 H -67.5 -39.9 2.0 0.017 0.0 HOH
 5.841
 CB
 O
ALA D:292 D:302 17.0 0.148 H -103.5 -14.5 17.0 0.148 0.0 HOH
 4.821
 O
 O
ALA E:292 E:302 6.0 0.052 H -74.1 -38.4 6.0 0.052 0.0 HOH
 5.363
 O
 O
ALA F:292 F:302 11.0 0.096 H -65.0 -37.4 11.0 0.096 0.0 HOH
 9.599
 CB
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:292 A:302 8.0 0.07 H -76.8 -23.2 8.0 0.07 0.0 HOH
 3.728
 CB
 O
ALA B:292 B:302 9.0 0.078 H -67.1 -38.6 9.0 0.078 0.0
ALA C:292 C:302 3.0 0.026 H -71.5 -29.2 3.0 0.026 0.0 HOH
 6.520
 O
 O
ALA D:292 D:302 6.0 0.052 H -72.2 -38.5 6.0 0.052 0.0 HOH
 9.160
 O
 O
ALA E:292 E:302 10.0 0.087 H -72.4 -31.4 10.0 0.087 0.0
ALA F:292 F:302 18.0 0.157 H -70.8 -32.4 18.0 0.157 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:292 A:302 7.0 0.061 H -72.0 -34.0 7.0 0.061 0.0 HOH
 9.949
 CB
 O
ALA B:292 B:302 15.0 0.13 H -62.5 -37.8 15.0 0.13 0.0
ALA C:292 C:302 5.0 0.043 H -67.8 -26.2 5.0 0.043 0.0 HOH
 3.526
 CB
 O
ALA D:292 D:302 8.0 0.07 H -72.0 -24.3 8.0 0.07 0.0
ALA E:292 E:302 14.0 0.122 H -78.6 -24.5 14.0 0.122 0.0 HOH
 4.728
 O
 O
ALA F:292 F:302 23.0 0.2 H -71.4 -27.5 23.0 0.2 0.0 HOH
 7.709
 N
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:292 A:302 14.0 0.122 H -72.5 -42.3 14.0 0.122 0.0 HOH
 3.672
 N
 O
ALA B:292 B:302 9.0 0.078 H -61.1 -31.7 9.0 0.078 0.0 HOH
 3.479
 N
 O
ALA C:292 C:302 18.0 0.157 H -70.3 -26.0 18.0 0.157 0.0 HOH
 3.083
 O
 O
ALA D:292 D:302 2.0 0.017 H -80.6 -26.7 2.0 0.017 0.0 HOH
 8.439
 N
 O
ALA E:292 E:302 8.0 0.07 H -75.8 -33.3 8.0 0.07 0.0 HOH
 3.556
 CB
 O
ALA F:292 F:302 15.0 0.13 H -57.5 -42.2 15.0 0.13 0.0 HOH
 3.365
 N
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:292 A:302 10.0 0.087 H -72.1 -32.8 10.0 0.087 0.0 HOH
 3.292
 O
 O
ALA B:292 B:302 14.0 0.122 H -74.8 -23.6 14.0 0.122 0.0 HOH
 3.619
 CB
 O
ALA C:292 C:302 2.0 0.017 H -66.3 -33.1 2.0 0.017 0.0 HOH
 3.595
 CB
 O
ALA D:292 D:302 5.0 0.043 H -86.7 -6.3 5.0 0.043 0.0 HOH
 4.778
 O
 O
ALA E:292 E:302 4.0 0.035 H -71.2 -38.0 4.0 0.035 0.0 HOH
 3.668
 CB
 O
ALA F:292 F:302 11.0 0.096 H -77.8 -36.1 11.0 0.096 0.0 HOH
 4.112
 N
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:292 A:302 17.0 0.148 H -72.9 -36.4 17.0 0.148 0.0 HOH
 5.604
 CB
 O
ALA B:292 B:302 3.0 0.026 H -65.3 -35.8 3.0 0.026 0.0 HOH
 3.961
 CB
 O
ALA C:292 C:302 7.0 0.061 H -74.6 -26.2 7.0 0.061 0.0 HOH
 3.127
 O
 O
ALA D:292 D:302 5.0 0.043 H -72.5 -33.9 5.0 0.043 0.0 HOH
 7.061
 N
 O
ALA E:292 E:302 1.0 0.009 H -81.1 -30.2 1.0 0.009 0.0 HOH
 5.059
 O
 O
ALA F:292 F:302 15.0 0.13 H -63.9 -31.9 15.0 0.13 0.0 HOH
 5.212
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:292 A:302 20.0 0.174 H -73.7 -31.1 20.0 0.174 0.0 HOH
 2.890
 O
 O
ALA B:292 B:302 14.0 0.122 H -74.1 -23.1 14.0 0.122 0.0 HOH
 3.454
 CB
 O
ALA C:292 C:302 0.0 0.0 H -71.4 -29.8 0.0 0.0 0.0 HOH
 2.492
 O
 O
ALA D:292 D:302 53.0 0.461 H -81.4 -31.9 53.0 0.461 0.0 HOH
 3.901
 CB
 O
ALA E:292 E:302 18.0 0.157 H -73.8 -35.7 18.0 0.157 0.0 HOH
 3.630
 CB
 O
ALA F:292 F:302 36.0 0.313 H -70.8 -33.3 36.0 0.313 0.0 HOH
 3.959
 CB
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 ALA A:292 A:302 19.0 0.165 H -77.4 -26.2 19.0 0.165 0.0 HOH
 9.538
 N
 O
ALA B:292 B:302 20.0 0.174 H -74.8 -39.0 20.0 0.174 0.0 HOH
 4.423
 CA
 O
ALA C:292 C:302 3.0 0.026 H -76.5 -28.6 3.0 0.026 0.0
ALA D:292 D:302 60.0 0.522 H -101.1 -11.5 60.0 0.522 0.0 HOH
 4.920
 O
 O
ALA E:292 E:302 14.0 0.122 H -91.8 -16.6 14.0 0.122 0.0 HOH
 7.536
 CB
 O
ALA F:292 F:302 37.0 0.322 H -90.1 -22.0 37.0 0.322 0.0 HOH
 5.124
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 ALA A:302 A:302 31.0 0.27 H -57.4 -31.2