Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11689060 . A C CCDS5985.1:NM_004462.3:c.913Aat>Cat_NP_004453.3:p.305N>H Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ASN A:275 A:305 56.0 0.35 T 55.1 27.1 56.0 0.35 0.0 HOH
 2.528
 OD1
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 ASN A:275 A:305 65.0 0.406 T 48.3 44.4 65.0 0.406 0.0 HOH
 6.052
 O
 O
ASN B:275 B:305 58.0 0.362 T 43.3 22.9 NA NA NA
ASN C:275 C:305 65.0 0.406 T 82.2 12.7 NA NA NA
ASN D:275 D:305 60.0 0.375 S 67.7 31.8 NA NA NA
ASN E:275 E:305 55.0 0.344 T 48.3 31.4 NA NA NA
ASN F:275 NA:NA DO NA DO DO DO NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ASN A:275 A:305 66.0 0.412 T 50.6 31.1 66.0 0.412 0.0 HOH
 3.510
 O
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ASN A:275 A:305 60.0 0.375 T 60.6 23.6 60.0 0.375 0.0 HOH
 2.815
 ND2
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 ASN A:275 A:305 62.0 0.388 T 57.7 24.0 62.0 0.388 0.0 HOH
 2.760
 O
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ASN A:278 A:305 64.0 0.4 T 57.0 28.3 64.0 0.4 0.0 HOH
 2.570
 OD1
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ASN A:278 A:305 58.0 0.362 T 58.1 27.0 58.0 0.362 0.0 HOH
 2.658
 OD1
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ASN A:278 A:305 59.0 0.369 T 55.2 28.3 59.0 0.369 0.0 HOH
 2.820
 ND2
 O
ASN B:278 B:305 63.0 0.394 T 57.8 29.3 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ASN A:278 A:305 63.0 0.394 T 52.0 32.2 63.0 0.394 0.0 HOH
 2.625
 OD1
 O
ASN B:278 B:305 53.0 0.331 T 49.6 30.0 53.0 0.331 0.0 HOH
 2.787
 ND2
 O
ASN C:278 C:305 55.0 0.344 T 53.1 24.0 55.0 0.344 0.0 HOH
 6.192
 OD1
 O
ASN D:278 D:305 59.0 0.369 T 49.3 35.6 NA NA NA
ASN E:278 E:305 58.0 0.362 T 50.3 24.2 NA NA NA
ASN F:278 F:305 63.0 0.394 T 48.2 32.1 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ASN A:278 A:305 55.0 0.344 T 55.7 30.6 55.0 0.344 0.0 HOH
 2.766
 O
 O
ASN B:278 B:305 57.0 0.356 T 51.6 34.2 57.0 0.356 0.0 HOH
 2.657
 O
 O
ASN C:278 C:305 60.0 0.375 T 56.8 29.1 60.0 0.375 0.0 HOH
 2.606
 OD1
 O
ASN D:278 D:305 63.0 0.394 T 53.9 27.6 NA NA NA
ASN E:278 E:305 58.0 0.362 T 55.5 36.9 NA NA NA
ASN F:278 F:305 57.0 0.356 T 54.5 28.1 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ASN A:278 A:305 59.0 0.369 T 49.8 17.3 59.0 0.369 0.0 HOH
 3.459
 O
 O
ASN B:278 B:305 64.0 0.4 T 53.5 36.2 64.0 0.4 0.0 HOH
 3.712
 ND2
 O
ASN C:278 C:305 58.0 0.362 T 60.0 17.3 58.0 0.362 0.0 HOH
 6.649
 ND2
 O
ASN D:278 D:305 58.0 0.362 T 51.2 35.6 NA NA NA
ASN E:278 E:305 61.0 0.381 T 62.6 26.4 NA NA NA
ASN F:278 F:305 59.0 0.369 T 44.0 37.5 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ASN A:278 A:305 57.0 0.356 T 57.4 31.2 57.0 0.356 0.0 HOH
 2.609
 OD1
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ASN A:278 A:305 61.0 0.381 T 57.7 29.2 61.0 0.381 0.0 HOH
 2.780
 O
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ASN A:278 A:305 56.0 0.35 T 48.3 32.7 56.0 0.35 0.0 HOH
 2.451
 OD1
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ASN A:278 A:305 54.0 0.338 T 57.3 32.2 54.0 0.338 0.0 HOH
 2.598
 OD1
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ASN A:278 A:305 61.0 0.381 T 53.1 24.1 61.0 0.381 0.0 HOH
 2.755
 O
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 ASN A:275 A:305 62.0 0.388 T 55.0 31.1 62.0 0.388 0.0 HOH
 2.615
 O
 O
ASN B:275 B:305 49.0 0.306 T 49.4 40.0 NA NA NA
ASN C:275 C:305 60.0 0.375 T 56.8 33.2 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ASN A:295 A:305 61.0 0.381 T 39.1 45.1 61.0 0.381 0.0 HOH
 6.416
 ND2
 O
ASN B:295 B:305 57.0 0.356 T 53.9 50.5 57.0 0.356 0.0
ASN C:295 C:305 47.0 0.294 T 58.5 26.5 47.0 0.294 0.0 HOH
 3.399
 OD1
 O
ASN D:295 D:305 53.0 0.331 T 69.1 -3.3 53.0 0.331 0.0 HOH
 6.825
 ND2
 O
ASN E:295 E:305 63.0 0.394 T 52.8 33.1 63.0 0.394 0.0 HOH
 2.878
 OD1
 O
ASN F:295 F:305 55.0 0.344 T 56.2 13.0 55.0 0.344 0.0 HOH
 6.616
 ND2
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ASN A:295 A:305 65.0 0.406 T 42.9 43.5 65.0 0.406 0.0 HOH
 3.192
 O
 O
ASN B:295 B:305 49.0 0.306 T 55.6 16.7 49.0 0.306 0.0 HOH
 8.350
 OD1
 O
ASN C:295 C:305 54.0 0.338 T 60.4 24.7 54.0 0.338 0.0 HOH
 2.690
 O
 O
ASN D:295 D:305 63.0 0.394 T 37.6 41.6 63.0 0.394 0.0 HOH
 8.270
 ND2
 O
ASN E:295 E:305 63.0 0.394 T 58.5 21.7 63.0 0.394 0.0 HOH
 2.905
 OD1
 O
ASN F:295 F:305 62.0 0.388 T 46.8 53.8 62.0 0.388 0.0 HOH
 8.535
 ND2
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ASN A:295 A:305 63.0 0.394 T 45.3 35.8 63.0 0.394 0.0 HOH
 3.719
 O
 O
ASN B:295 B:305 65.0 0.406 T 53.6 33.1 65.0 0.406 0.0
ASN C:295 C:305 61.0 0.381 T 50.1 30.9 61.0 0.381 0.0 HOH
 3.586
 O
 O
ASN D:295 D:305 58.0 0.362 T 52.0 40.9 58.0 0.362 0.0 HOH
 7.368
 O
 O
ASN E:295 E:305 64.0 0.4 T 46.7 41.0 64.0 0.4 0.0 HOH
 4.826
 OD1
 O
ASN F:295 F:305 62.0 0.388 T 47.2 35.1 62.0 0.388 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ASN A:295 A:305 57.0 0.356 T 44.4 34.6 57.0 0.356 0.0 HOH
 5.335
 OD1
 O
ASN B:295 B:305 64.0 0.4 T 46.6 37.8 64.0 0.4 0.0
ASN C:295 C:305 62.0 0.388 T 48.6 42.3 62.0 0.388 0.0 HOH
 3.761
 O
 O
ASN D:295 D:305 55.0 0.344 T 59.7 17.9 55.0 0.344 0.0
ASN E:295 E:305 61.0 0.381 T 51.2 33.5 61.0 0.381 0.0 HOH
 3.629
 O
 O
ASN F:295 F:305 58.0 0.362 T 49.0 28.9 58.0 0.362 0.0
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ASN A:295 A:305 62.0 0.388 T 46.6 30.4 62.0 0.388 0.0 HOH
 3.179
 O
 O
ASN B:295 B:305 60.0 0.375 T 47.4 43.8 60.0 0.375 0.0 HOH
 6.299
 ND2
 O
ASN C:295 C:305 51.0 0.319 T 46.3 38.8 51.0 0.319 0.0 HOH
 3.448
 OD1
 O
ASN D:295 D:305 61.0 0.381 T 48.1 35.5 61.0 0.381 0.0 HOH
 6.544
 OD1
 O
ASN E:295 E:305 59.0 0.369 T 56.8 25.9 59.0 0.369 0.0 HOH
 2.940
 OD1
 O
ASN F:295 F:305 62.0 0.388 T 45.8 51.3 62.0 0.388 0.0 HOH
 9.257
 ND2
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ASN A:295 A:305 61.0 0.381 T 47.5 39.1 61.0 0.381 0.0 HOH
 4.709
 OD1
 O
ASN B:295 B:305 60.0 0.375 T 41.6 36.4 60.0 0.375 0.0 HOH
 6.599
 O
 O
ASN C:295 C:305 46.0 0.287 T 44.4 37.3 46.0 0.287 0.0 HOH
 7.662
 OD1
 O
ASN D:295 D:305 64.0 0.4 T 45.4 41.2 64.0 0.4 0.0 HOH
 4.328
 O
 O
ASN E:295 E:305 59.0 0.369 T 45.4 33.4 59.0 0.369 0.0 HOH
 2.988
 OD1
 O
ASN F:295 F:305 60.0 0.375 T 49.1 32.8 60.0 0.375 0.0 HOH
 4.067
 ND2
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ASN A:295 A:305 59.0 0.369 T 49.8 31.5 59.0 0.369 0.0 HOH
 2.681
 OD1
 O
ASN B:295 B:305 58.0 0.362 T 43.0 33.6 58.0 0.362 0.0 HOH
 4.721
 OD1
 O
ASN C:295 C:305 50.0 0.312 T 48.2 34.7 50.0 0.312 0.0 HOH
 2.642
 ND2
 O
ASN D:295 D:305 55.0 0.344 T 48.7 30.3 55.0 0.344 0.0 HOH
 7.004
 CB
 O
ASN E:295 E:305 65.0 0.406 T 52.4 36.5 65.0 0.406 0.0 HOH
 2.823
 OD1
 O
ASN F:295 F:305 65.0 0.406 T 45.3 53.0 65.0 0.406 0.0 HOH
 2.632
 OD1
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ASN A:295 A:305 63.0 0.394 T 49.8 30.4 63.0 0.394 0.0 HOH
 3.335
 ND2
 O
ASN B:295 B:305 60.0 0.375 T 45.6 36.8 60.0 0.375 0.0 HOH
 2.874
 OD1
 O
ASN C:295 C:305 45.0 0.281 T 49.7 39.0 45.0 0.281 0.0 HOH
 3.227
 OD1
 O
ASN D:295 D:305 63.0 0.394 T 51.1 32.4 63.0 0.394 0.0
ASN E:295 E:305 65.0 0.406 T 48.2 34.1 65.0 0.406 0.0 HOH
 2.740
 OD1
 O
ASN F:295 F:305 63.0 0.394 T 50.9 28.1 63.0 0.394 0.0 HOH
 6.437
 OD1
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 ASN A:295 A:305 64.0 0.4 T 47.1 28.9 64.0 0.4 0.0
ASN B:295 B:305 55.0 0.344 T 56.8 11.8 55.0 0.344 0.0 HOH
 6.937
 OD1
 O
ASN C:295 C:305 51.0 0.319 T 57.8 23.8 51.0 0.319 0.0
ASN D:295 D:305 67.0 0.419 T 44.5 50.6 67.0 0.419 0.0 HOH
 3.406
 O
 O
ASN E:295 E:305 63.0 0.394 T 50.2 46.7 63.0 0.394 0.0 HOH
 6.396
 OD1
 O
ASN F:295 F:305 64.0 0.4 T 61.0 11.6 64.0 0.4 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 ASN A:305 A:305 63.0 0.394 T 49.9 35.9