Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11689072 . G A CCDS5985.1:NM_004462.3:c.925Gtg>Atg_NP_004453.3:p.309V>M Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 VAL A:279 A:309 0.0 0.0 G -50.7 -34.2 0.0 0.0 0.0 HOH
 2.704
 O
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 VAL A:279 A:309 4.0 0.026 G -56.0 -31.8 4.0 0.026 0.0 HOH
 8.070
 O
 O
VAL B:279 B:309 2.0 0.013 G -72.3 -19.5 NA NA NA
VAL C:279 C:309 1.0 0.006 G -66.0 2.4 NA NA NA
VAL D:279 D:309 5.0 0.032 T -39.9 -44.8 NA NA NA
VAL E:279 E:309 2.0 0.013 G -74.2 -3.6 NA NA NA
VAL F:279 NA:NA DO NA DO DO DO NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 VAL A:279 A:309 0.0 0.0 G -55.0 -35.2 0.0 0.0 0.0 HOH
 2.846
 O
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 VAL A:279 A:309 0.0 0.0 G -48.3 -36.4 0.0 0.0 0.0 HOH
 2.593
 O
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 VAL A:279 A:309 0.0 0.0 G -52.6 -30.7 0.0 0.0 0.0 HOH
 2.618
 O
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 VAL A:282 A:309 2.0 0.013 G -57.6 -32.3 2.0 0.013 0.0 HOH
 2.704
 O
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 VAL A:282 A:309 5.0 0.032 H -54.7 -36.2 5.0 0.032 0.0 HOH
 2.651
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 VAL A:282 A:309 0.0 0.0 G -55.5 -34.4 0.0 0.0 0.0 HOH
 2.615
 O
 O
VAL B:282 B:309 6.0 0.039 H -53.6 -35.0 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 VAL A:282 A:309 11.0 0.071 G -53.6 -28.2 11.0 0.071 0.0 HOH
 2.658
 O
 O
VAL B:282 B:309 6.0 0.039 G -63.6 -30.1 6.0 0.039 0.0 HOH
 2.795
 O
 O
VAL C:282 C:309 5.0 0.032 H -65.2 -23.0 5.0 0.032 0.0 HOH
 8.691
 CG1
 O
VAL D:282 D:309 2.0 0.013 G -58.0 -30.5 NA NA NA
VAL E:282 E:309 6.0 0.039 G -51.5 -26.6 NA NA NA
VAL F:282 F:309 16.0 0.103 G -72.3 -26.9 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 VAL A:282 A:309 0.0 0.0 G -55.1 -33.3 0.0 0.0 0.0 HOH
 2.644
 O
 O
VAL B:282 B:309 1.0 0.006 G -47.5 -36.6 1.0 0.006 0.0 HOH
 2.736
 O
 O
VAL C:282 C:309 2.0 0.013 G -48.5 -36.5 2.0 0.013 0.0 HOH
 2.617
 O
 O
VAL D:282 D:309 5.0 0.032 G -50.0 -34.3 NA NA NA
VAL E:282 E:309 0.0 0.0 G -57.0 -33.9 NA NA NA
VAL F:282 F:309 0.0 0.0 G -60.2 -31.5 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 VAL A:282 A:309 2.0 0.013 G -47.2 -34.5 2.0 0.013 0.0 HOH
 2.906
 O
 O
VAL B:282 B:309 1.0 0.006 G -54.6 -22.0 1.0 0.006 0.0 HOH
 8.129
 O
 O
VAL C:282 C:309 1.0 0.006 G -56.0 -21.2 1.0 0.006 0.0
VAL D:282 D:309 1.0 0.006 G -48.1 -32.7 NA NA NA
VAL E:282 E:309 0.0 0.0 G -73.4 -20.5 NA NA NA
VAL F:282 F:309 2.0 0.013 G -69.5 -19.0 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 VAL A:282 A:309 0.0 0.0 G -51.4 -34.9 0.0 0.0 0.0 HOH
 2.617
 O
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 VAL A:282 A:309 0.0 0.0 G -54.0 -34.7 0.0 0.0 0.0 HOH
 2.526
 O
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 VAL A:282 A:309 8.0 0.052 G -54.8 -32.8 8.0 0.052 0.0 HOH
 2.598
 O
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 VAL A:282 A:309 1.0 0.006 G -56.3 -35.9 1.0 0.006 0.0 HOH
 2.649
 O
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 VAL A:282 A:309 0.0 0.0 G -54.1 -33.0 0.0 0.0 0.0 HOH
 2.847
 O
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 VAL A:279 A:309 1.0 0.006 G -59.4 -30.5 1.0 0.006 0.0 HOH
 2.779
 O
 O
VAL B:279 B:309 7.0 0.045 G -52.5 -33.3 NA NA NA
VAL C:279 C:309 8.0 0.052 G -58.1 -33.6 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 VAL A:299 A:309 2.0 0.013 G -44.7 -41.7 2.0 0.013 0.0 HOH
 5.373
 O
 O
VAL B:299 B:309 2.0 0.013 G -48.5 -24.6 2.0 0.013 0.0
VAL C:299 C:309 2.0 0.013 G -63.9 -35.6 2.0 0.013 0.0 HOH
 7.546
 N
 O
VAL D:299 D:309 2.0 0.013 G -47.8 -38.8 2.0 0.013 0.0 HOH
 4.943
 CA
 O
VAL E:299 E:309 3.0 0.019 H -67.0 -18.1 3.0 0.019 0.0 HOH
 6.937
 C
 O
VAL F:299 F:309 6.0 0.039 H -57.6 -9.2 6.0 0.039 0.0 HOH
 9.278
 O
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 VAL A:299 A:309 0.0 0.0 G -44.3 -34.1 0.0 0.0 0.0 HOH
 4.063
 O
 O
VAL B:299 B:309 2.0 0.013 G -54.9 -29.5 2.0 0.013 0.0
VAL C:299 C:309 1.0 0.006 G -50.2 -24.8 1.0 0.006 0.0 HOH
 5.415
 N
 O
VAL D:299 D:309 1.0 0.006 G -67.8 -34.7 1.0 0.006 0.0 HOH
 8.111
 N
 O
VAL E:299 E:309 1.0 0.006 G -50.9 -10.3 1.0 0.006 0.0 HOH
 4.480
 O
 O
VAL F:299 F:309 0.0 0.0 T -93.9 -29.5 0.0 0.0 0.0 HOH
 9.514
 N
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 VAL A:299 A:309 3.0 0.019 H -62.9 -30.5 3.0 0.019 0.0 HOH
 2.779
 O
 O
VAL B:299 B:309 2.0 0.013 G -54.6 -32.9 2.0 0.013 0.0
VAL C:299 C:309 3.0 0.019 G -57.7 -29.9 3.0 0.019 0.0 HOH
 9.822
 CG2
 O
VAL D:299 D:309 1.0 0.006 G -52.3 -37.9 1.0 0.006 0.0 HOH
 5.967
 N
 O
VAL E:299 E:309 2.0 0.013 H -50.7 -34.8 2.0 0.013 0.0 HOH
 2.979
 O
 O
VAL F:299 F:309 1.0 0.006 H -53.1 -40.9 1.0 0.006 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 VAL A:299 A:309 0.0 0.0 G -60.6 -29.6 0.0 0.0 0.0
VAL B:299 B:309 0.0 0.0 G -57.9 -33.6 0.0 0.0 0.0
VAL C:299 C:309 1.0 0.006 G -57.6 -28.8 1.0 0.006 0.0 HOH
 4.360
 O
 O
VAL D:299 D:309 0.0 0.0 G -56.0 -37.8 0.0 0.0 0.0
VAL E:299 E:309 1.0 0.006 G -51.1 -35.3 1.0 0.006 0.0 HOH
 2.647
 O
 O
VAL F:299 F:309 1.0 0.006 G -70.4 -32.1 1.0 0.006 0.0 HOH
 3.097
 O
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 VAL A:299 A:309 2.0 0.013 G -49.9 -35.3 2.0 0.013 0.0 HOH
 2.612
 O
 O
VAL B:299 B:309 2.0 0.013 G -58.0 -27.5 2.0 0.013 0.0 HOH
 7.627
 C
 O
VAL C:299 C:309 0.0 0.0 G -59.7 -34.0 0.0 0.0 0.0 HOH
 6.592
 N
 O
VAL D:299 D:309 1.0 0.006 G -64.9 -27.8 1.0 0.006 0.0
VAL E:299 E:309 2.0 0.013 G -51.0 -32.2 2.0 0.013 0.0 HOH
 2.727
 O
 O
VAL F:299 F:309 1.0 0.006 G -59.9 -36.6 1.0 0.006 0.0 HOH
 2.504
 O
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 VAL A:299 A:309 1.0 0.006 G -60.6 -31.6 1.0 0.006 0.0 HOH
 2.785
 O
 O
VAL B:299 B:309 3.0 0.019 G -51.5 -26.7 3.0 0.019 0.0 HOH
 4.010
 CA
 O
VAL C:299 C:309 1.0 0.006 G -62.1 -27.7 1.0 0.006 0.0 HOH
 2.738
 O
 O
VAL D:299 D:309 1.0 0.006 G -57.6 -38.0 1.0 0.006 0.0 HOH
 6.825
 N
 O
VAL E:299 E:309 1.0 0.006 G -55.0 -25.2 1.0 0.006 0.0 HOH
 2.833
 O
 O
VAL F:299 F:309 0.0 0.0 H -65.9 -17.3 0.0 0.0 0.0
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 VAL A:299 A:309 0.0 0.0 G -50.6 -39.4 0.0 0.0 0.0 HOH
 2.760
 O
 O
VAL B:299 B:309 2.0 0.013 G -58.1 -27.2 2.0 0.013 0.0 HOH
 6.250
 N
 O
VAL C:299 C:309 1.0 0.006 G -63.5 -31.5 1.0 0.006 0.0 HOH
 2.732
 O
 O
VAL D:299 D:309 2.0 0.013 G -67.3 -28.4 2.0 0.013 0.0 HOH
 6.965
 O
 O
VAL E:299 E:309 3.0 0.019 G -53.3 -27.0 3.0 0.019 0.0 HOH
 2.788
 O
 O
VAL F:299 F:309 4.0 0.026 G -50.6 -28.3 4.0 0.026 0.0 HOH
 2.969
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 VAL A:299 A:309 0.0 0.0 G -56.3 -32.4 0.0 0.0 0.0 HOH
 2.690
 O
 O
VAL B:299 B:309 1.0 0.006 G -59.7 -37.7 1.0 0.006 0.0 HOH
 6.090
 N
 O
VAL C:299 C:309 0.0 0.0 G -52.8 -36.7 0.0 0.0 0.0 HOH
 2.611
 O
 O
VAL D:299 D:309 17.0 0.11 G -55.3 -42.7 17.0 0.11 0.0 HOH
 2.714
 O
 O
VAL E:299 E:309 1.0 0.006 G -57.4 -27.2 1.0 0.006 0.0 HOH
 2.864
 O
 O
VAL F:299 F:309 1.0 0.006 G -54.9 -26.5 1.0 0.006 0.0
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 VAL A:299 A:309 1.0 0.006 G -56.1 -33.2 1.0 0.006 0.0 HOH
 4.949
 O
 O
VAL B:299 B:309 2.0 0.013 G -60.5 -21.8 2.0 0.013 0.0
VAL C:299 C:309 0.0 0.0 G -56.1 -19.6 0.0 0.0 0.0
VAL D:299 D:309 18.0 0.116 G -72.7 -5.2 18.0 0.116 0.0 HOH
 5.056
 C
 O
VAL E:299 E:309 4.0 0.026 H -60.1 -20.9 4.0 0.026 0.0
VAL F:299 F:309 3.0 0.019 G -71.2 -25.2 3.0 0.019 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 VAL A:309 A:309 1.0 0.006 G -54.0 -32.8