Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11689077 . C A CCDS5985.1:NM_004462.3:c.930ttC>ttA_NP_004453.3:p.310F>L Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 PHE A:280 A:310 8.0 0.038 G -90.4 -0.1 8.0 0.038 0.0 HOH
 2.706
 O
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 PHE A:280 A:310 10.0 0.048 G -109.5 8.2 10.0 0.048 0.0 HOH
 7.385
 CD2
 O
PHE B:280 B:310 5.0 0.024 S -110.8 -18.2 NA NA NA
PHE C:280 C:310 4.0 0.019 G -121.4 -0.9 NA NA NA
PHE D:280 D:310 27.0 0.129 T -94.5 -20.9 NA NA NA
PHE E:280 E:310 11.0 0.052 G -121.0 14.1 NA NA NA
PHE F:280 NA:NA DO NA DO DO DO NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 PHE A:280 A:310 9.0 0.043 G -92.2 5.9 9.0 0.043 0.0 HOH
 4.365
 CB
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 PHE A:280 A:310 7.0 0.033 G -91.3 5.5 7.0 0.033 0.0 HOH
 2.940
 O
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 PHE A:280 A:310 8.0 0.038 G -94.2 5.2 8.0 0.038 0.0 HOH
 2.677
 O
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 PHE A:283 A:310 9.0 0.043 G -90.9 4.0 9.0 0.043 0.0 HOH
 2.692
 O
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 PHE A:283 A:310 7.0 0.033 H -100.5 -26.5 7.0 0.033 0.0 HOH
 3.017
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 PHE A:283 A:310 5.0 0.024 G -94.8 7.4 5.0 0.024 0.0 HOH
 4.452
 CB
 O
PHE B:283 B:310 8.0 0.038 H -102.8 -25.6 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 PHE A:283 A:310 6.0 0.029 T -102.2 -12.3 6.0 0.029 0.0 HOH
 4.906
 N
 O
PHE B:283 B:310 5.0 0.024 T -112.7 -29.0 5.0 0.024 0.0 HOH
 5.048
 N
 O
PHE C:283 C:310 13.0 0.062 H -106.1 -19.2 13.0 0.062 0.0 HOH
 9.230
 CE1
 O
PHE D:283 D:310 9.0 0.043 G -98.4 -5.2 NA NA NA
PHE E:283 E:310 5.0 0.024 T -104.0 -24.7 NA NA NA
PHE F:283 F:310 8.0 0.038 T -97.7 -46.1 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 PHE A:283 A:310 7.0 0.033 G -92.6 3.1 7.0 0.033 0.0 HOH
 4.335
 CB
 O
PHE B:283 B:310 9.0 0.043 G -96.8 4.0 9.0 0.043 0.0 HOH
 4.399
 CB
 O
PHE C:283 C:310 8.0 0.038 G -95.6 -3.1 8.0 0.038 0.0 HOH
 2.496
 O
 O
PHE D:283 D:310 11.0 0.052 G -100.4 5.1 NA NA NA
PHE E:283 E:310 6.0 0.029 G -91.6 12.3 NA NA NA
PHE F:283 F:310 11.0 0.052 T -95.7 -9.9 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 PHE A:283 A:310 5.0 0.024 G -97.5 -3.8 5.0 0.024 0.0 HOH
 5.148
 N
 O
PHE B:283 B:310 8.0 0.038 G -108.4 -7.0 8.0 0.038 0.0 HOH
 7.744
 O
 O
PHE C:283 C:310 13.0 0.062 G -109.4 10.0 13.0 0.062 0.0
PHE D:283 D:310 9.0 0.043 G -97.2 4.0 NA NA NA
PHE E:283 E:310 12.0 0.057 G -94.5 7.9 NA NA NA
PHE F:283 F:310 14.0 0.067 G -95.8 21.4 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 PHE A:283 A:310 9.0 0.043 G -88.4 4.3 9.0 0.043 0.0 HOH
 2.538
 O
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 PHE A:283 A:310 9.0 0.043 G -87.9 2.0 9.0 0.043 0.0 HOH
 2.833
 O
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 PHE A:283 A:310 11.0 0.052 G -84.3 -5.5 11.0 0.052 0.0 HOH
 2.782
 O
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 PHE A:283 A:310 8.0 0.038 G -81.9 -3.7 8.0 0.038 0.0 HOH
 2.600
 O
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 PHE A:283 A:310 8.0 0.038 G -88.0 -0.6 8.0 0.038 0.0 HOH
 3.856
 CB
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 PHE A:280 A:310 7.0 0.033 G -94.2 -5.4 7.0 0.033 0.0 HOH
 4.168
 CB
 O
PHE B:280 B:310 7.0 0.033 G -100.2 11.5 NA NA NA
PHE C:280 C:310 9.0 0.043 G -94.3 0.7 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:300 A:310 8.0 0.038 G -91.9 -2.5 8.0 0.038 0.0 HOH
 6.280
 O
 O
PHE B:300 B:310 3.0 0.014 G -112.1 43.6 3.0 0.014 0.0
PHE C:300 C:310 9.0 0.043 G -96.1 7.4 9.0 0.043 0.0 HOH
 8.122
 CE2
 O
PHE D:300 D:310 10.0 0.048 G -93.6 14.1 10.0 0.048 0.0 HOH
 6.774
 N
 O
PHE E:300 E:310 9.0 0.043 H -107.2 -4.2 9.0 0.043 0.0 HOH
 3.406
 O
 O
PHE F:300 F:310 9.0 0.043 H -117.6 -20.8 9.0 0.043 0.0 HOH
 5.224
 O
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:300 A:310 10.0 0.048 G -100.2 10.5 10.0 0.048 0.0 HOH
 6.207
 N
 O
PHE B:300 B:310 6.0 0.029 G -101.4 17.6 6.0 0.029 0.0
PHE C:300 C:310 10.0 0.048 G -107.5 21.7 10.0 0.048 0.0 HOH
 6.122
 C
 O
PHE D:300 D:310 6.0 0.029 G -98.0 14.0 6.0 0.029 0.0 HOH
 8.715
 C
 O
PHE E:300 E:310 9.0 0.043 G -118.6 5.2 9.0 0.043 0.0 HOH
 6.407
 N
 O
PHE F:300 F:310 12.0 0.057 S -100.6 34.5 12.0 0.057 0.0
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:300 A:310 11.0 0.052 H -98.1 -7.9 11.0 0.052 0.0 HOH
 5.013
 N
 O
PHE B:300 B:310 8.0 0.038 G -95.2 1.9 8.0 0.038 0.0
PHE C:300 C:310 12.0 0.057 G -98.3 1.7 12.0 0.057 0.0 HOH
 8.377
 O
 O
PHE D:300 D:310 11.0 0.052 G -92.6 1.1 11.0 0.052 0.0 HOH
 7.187
 N
 O
PHE E:300 E:310 11.0 0.052 H -100.0 -6.3 11.0 0.052 0.0 HOH
 3.596
 O
 O
PHE F:300 F:310 10.0 0.048 H -89.7 -11.4 10.0 0.048 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:300 A:310 7.0 0.033 G -99.7 13.6 7.0 0.033 0.0 HOH
 7.697
 CE2
 O
PHE B:300 B:310 7.0 0.033 G -93.9 -2.4 7.0 0.033 0.0
PHE C:300 C:310 10.0 0.048 G -97.0 3.7 10.0 0.048 0.0 HOH
 6.495
 N
 O
PHE D:300 D:310 4.0 0.019 G -92.3 7.4 4.0 0.019 0.0
PHE E:300 E:310 10.0 0.048 G -98.8 6.9 10.0 0.048 0.0 HOH
 4.835
 N
 O
PHE F:300 F:310 9.0 0.043 T -94.1 -5.2 9.0 0.043 0.0 HOH
 5.337
 N
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:300 A:310 8.0 0.038 G -93.2 10.5 8.0 0.038 0.0 HOH
 4.824
 N
 O
PHE B:300 B:310 9.0 0.043 G -102.2 17.0 9.0 0.043 0.0 HOH
 4.154
 CB
 O
PHE C:300 C:310 10.0 0.048 G -95.3 1.0 10.0 0.048 0.0 HOH
 3.892
 O
 O
PHE D:300 D:310 10.0 0.048 G -102.8 12.4 10.0 0.048 0.0
PHE E:300 E:310 9.0 0.043 G -100.8 12.4 9.0 0.043 0.0 HOH
 3.467
 O
 O
PHE F:300 F:310 11.0 0.052 T -87.3 -16.1 11.0 0.052 0.0 HOH
 4.607
 N
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:300 A:310 10.0 0.048 G -96.1 11.3 10.0 0.048 0.0 HOH
 5.024
 N
 O
PHE B:300 B:310 8.0 0.038 G -103.8 -4.3 8.0 0.038 0.0 HOH
 5.811
 N
 O
PHE C:300 C:310 10.0 0.048 G -99.8 12.8 10.0 0.048 0.0 HOH
 4.975
 N
 O
PHE D:300 D:310 8.0 0.038 G -89.5 10.4 8.0 0.038 0.0 HOH
 9.468
 N
 O
PHE E:300 E:310 10.0 0.048 G -102.8 4.6 10.0 0.048 0.0 HOH
 5.076
 N
 O
PHE F:300 F:310 9.0 0.043 H -108.5 -23.5 9.0 0.043 0.0 HOH
 8.339
 O
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:300 A:310 9.0 0.043 G -90.6 4.6 9.0 0.043 0.0 HOH
 4.125
 CB
 O
PHE B:300 B:310 8.0 0.038 G -105.4 -0.9 8.0 0.038 0.0 HOH
 8.213
 CE2
 O
PHE C:300 C:310 11.0 0.052 G -95.4 0.9 11.0 0.052 0.0 HOH
 4.879
 O
 O
PHE D:300 D:310 12.0 0.057 G -96.6 0.9 12.0 0.057 0.0 HOH
 9.159
 N
 O
PHE E:300 E:310 10.0 0.048 G -105.2 8.1 10.0 0.048 0.0 HOH
 3.887
 O
 O
PHE F:300 F:310 13.0 0.062 G -103.4 13.1 13.0 0.062 0.0 HOH
 4.253
 CB
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 PHE A:300 A:310 8.0 0.038 G -93.9 8.6 8.0 0.038 0.0 HOH
 4.931
 N
 O
PHE B:300 B:310 7.0 0.033 G -90.8 -6.6 7.0 0.033 0.0 HOH
 4.256
 CB
 O
PHE C:300 C:310 11.0 0.052 G -93.9 17.6 11.0 0.052 0.0 HOH
 4.813
 N
 O
PHE D:300 D:310 7.0 0.033 G -90.8 20.9 7.0 0.033 0.0 HOH
 4.899
 N
 O
PHE E:300 E:310 11.0 0.052 G -102.6 5.3 11.0 0.052 0.0 HOH
 3.552
 O
 O
PHE F:300 F:310 11.0 0.052 G -107.2 39.0 11.0 0.052 0.0
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 PHE A:300 A:310 6.0 0.029 G -99.3 6.9 6.0 0.029 0.0 HOH
 7.079
 N
 O
PHE B:300 B:310 8.0 0.038 T -106.9 -10.1 8.0 0.038 0.0
PHE C:300 C:310 12.0 0.057 G -112.1 16.6 12.0 0.057 0.0
PHE D:300 D:310 11.0 0.052 G -121.0 26.2 11.0 0.052 0.0 HOH
 5.480
 N
 O
PHE E:300 E:310 15.0 0.071 H -108.7 -13.8 15.0 0.071 0.0
PHE F:300 F:310 10.0 0.048 G -103.1 5.2 10.0 0.048 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 PHE A:310 A:310 7.0 0.033 G -93.2 -7.3