Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11689084 . G A CCDS5985.1:NM_004462.3:c.937Gca>Aca_NP_004453.3:p.313A>T Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:283 A:313 66.0 0.574 -100.5 104.1 66.0 0.574 0.0 HOH
 2.603
 O
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 ALA A:283 A:313 82.0 0.713 -124.7 152.0 82.0 0.713 0.0 HOH
 7.789
 CA
 O
ALA B:283 B:313 94.0 0.817 -93.0 147.4 NA NA NA
ALA C:283 C:313 87.0 0.757 -70.0 160.2 NA NA NA
ALA D:283 D:313 97.0 0.843 -109.9 150.9 NA NA NA
ALA E:283 E:313 92.0 0.8 -95.8 146.1 NA NA NA
ALA F:283 NA:NA DO NA DO DO DO NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:283 A:313 76.0 0.661 -102.1 108.8 76.0 0.661 0.0 HOH
 3.243
 CA
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 ALA A:283 A:313 81.0 0.704 -90.7 116.9 81.0 0.704 0.0 HOH
 3.414
 CB
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 ALA A:283 A:313 78.0 0.678 -92.0 108.7 78.0 0.678 0.0 HOH
 2.923
 N
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:286 A:313 65.0 0.565 -118.7 65.8 65.0 0.565 0.0 HOH
 4.101
 O
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:286 A:313 79.0 0.687 -132.5 115.3 79.0 0.687 0.0 HOH
 2.687
 O
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:286 A:313 53.0 0.461 -94.8 103.4 53.0 0.461 0.0 HOH
 3.319
 CB
 O
ALA B:286 B:313 79.0 0.687 -127.0 113.8 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:286 A:313 111.0 0.965 165.5 360.0 111.0 0.965 0.0 HOH
 3.260
 O
 O
ALA B:286 B:313 71.0 0.617 -136.7 135.9 71.0 0.617 0.0 HOH
 6.455
 CA
 O
ALA C:286 C:313 97.0 0.843 69.5 -103.8 97.0 0.843 0.0
ALA D:286 D:313 99.0 0.861 -95.8 78.7 NA NA NA
ALA E:286 E:313 79.0 0.687 -141.4 142.3 NA NA NA
ALA F:286 NA:NA DO NA DO DO DO NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 ALA A:286 A:313 78.0 0.678 -87.3 132.7 78.0 0.678 0.0 HOH
 2.906
 O
 O
ALA B:286 B:313 92.0 0.8 -89.2 134.8 92.0 0.8 0.0 HOH
 4.252
 CA
 O
ALA C:286 C:313 88.0 0.765 -88.4 125.7 88.0 0.765 0.0 HOH
 4.267
 C
 O
ALA D:286 D:313 64.0 0.557 -60.0 121.6 NA NA NA
ALA E:286 E:313 88.0 0.765 -81.6 141.2 NA NA NA
ALA F:286 F:313 79.0 0.687 -75.5 128.7 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:286 A:313 85.0 0.739 -88.1 155.8 85.0 0.739 0.0 HOH
 6.032
 N
 O
ALA B:286 B:313 80.0 0.696 S -78.3 147.2 80.0 0.696 0.0 HOH
 3.086
 N
 O
ALA C:286 C:313 99.0 0.861 -78.1 145.2 99.0 0.861 0.0
ALA D:286 D:313 90.0 0.783 -87.2 135.0 NA NA NA
ALA E:286 E:313 77.0 0.67 -103.9 123.6 NA NA NA
ALA F:286 F:313 96.0 0.835 -97.0 149.1 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:286 A:313 102.0 0.887 -73.9 132.6 102.0 0.887 0.0 HOH
 3.021
 N
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 ALA A:286 A:313 54.0 0.47 -90.0 118.2 54.0 0.47 0.0 HOH
 3.284
 CB
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:286 A:313 53.0 0.461 -137.7 135.1 53.0 0.461 0.0 HOH
 2.830
 CB
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:286 A:313 102.0 0.887 -76.4 135.6 102.0 0.887 0.0 HOH
 2.971
 N
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 ALA A:286 A:313 67.0 0.583 -93.5 116.6 67.0 0.583 0.0 HOH
 2.742
 O
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 ALA A:283 A:313 94.0 0.817 -87.0 129.8 94.0 0.817 0.0 HOH
 3.563
 CA
 O
ALA B:283 B:313 95.0 0.826 -48.7 137.7 NA NA NA
ALA C:283 C:313 95.0 0.826 -96.6 150.4 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:303 A:313 69.0 0.6 -127.7 141.0 69.0 0.6 0.0 HOH
 3.691
 CA
 O
ALA B:303 B:313 92.0 0.8 -76.0 151.4 92.0 0.8 0.0 HOH
 9.570
 CB
 O
ALA C:303 C:313 101.0 0.878 -114.1 138.9 101.0 0.878 0.0 HOH
 5.805
 O
 O
ALA D:303 D:313 80.0 0.696 -95.7 151.7 80.0 0.696 0.0 HOH
 3.043
 CA
 O
ALA E:303 E:313 80.0 0.696 -122.0 137.8 80.0 0.696 0.0 HOH
 8.288
 CB
 O
ALA F:303 F:313 77.0 0.67 -154.5 156.7 77.0 0.67 0.0 HOH
 6.373
 N
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:303 A:313 73.0 0.635 -106.8 137.2 73.0 0.635 0.0 HOH
 5.427
 O
 O
ALA B:303 B:313 99.0 0.861 -100.4 98.7 99.0 0.861 0.0 HOH
 8.348
 O
 O
ALA C:303 C:313 93.0 0.809 -79.9 134.4 93.0 0.809 0.0 HOH
 2.686
 O
 O
ALA D:303 D:313 86.0 0.748 -83.2 173.5 86.0 0.748 0.0 HOH
 6.130
 CB
 O
ALA E:303 E:313 89.0 0.774 -108.5 151.3 89.0 0.774 0.0 HOH
 5.845
 CA
 O
ALA F:303 F:313 78.0 0.678 -86.3 129.4 78.0 0.678 0.0 HOH
 6.117
 N
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:303 A:313 90.0 0.783 -91.3 153.4 90.0 0.783 0.0 HOH
 3.621
 CA
 O
ALA B:303 B:313 92.0 0.8 -70.7 145.3 92.0 0.8 0.0 HOH
 5.442
 CB
 O
ALA C:303 C:313 94.0 0.817 -85.4 149.4 94.0 0.817 0.0
ALA D:303 D:313 91.0 0.791 -72.9 143.5 91.0 0.791 0.0 HOH
 8.386
 N
 O
ALA E:303 E:313 87.0 0.757 -88.8 159.1 87.0 0.757 0.0 HOH
 5.841
 CA
 O
ALA F:303 F:313 94.0 0.817 -61.3 140.4 94.0 0.817 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:303 A:313 87.0 0.757 -95.2 149.7 87.0 0.757 0.0 HOH
 9.999
 CB
 O
ALA B:303 B:313 88.0 0.765 -90.9 132.8 88.0 0.765 0.0 HOH
 9.823
 CB
 O
ALA C:303 C:313 83.0 0.722 -82.7 146.5 83.0 0.722 0.0 HOH
 4.130
 N
 O
ALA D:303 D:313 96.0 0.835 -79.7 122.8 96.0 0.835 0.0 HOH
 8.700
 CB
 O
ALA E:303 E:313 89.0 0.774 -95.5 157.9 89.0 0.774 0.0 HOH
 5.543
 CA
 O
ALA F:303 F:313 80.0 0.696 -89.8 150.5 80.0 0.696 0.0 8PH
HOH
 9.467
4.959
 CB
CA
 OAC
O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:303 A:313 88.0 0.765 -105.3 158.7 88.0 0.765 0.0 HOH
 4.148
 CA
 O
ALA B:303 B:313 94.0 0.817 -68.8 143.9 94.0 0.817 0.0 HOH
 7.984
 CB
 O
ALA C:303 C:313 99.0 0.861 -100.5 122.1 99.0 0.861 0.0 HOH
 4.510
 CB
 O
ALA D:303 D:313 99.0 0.861 -75.6 146.1 99.0 0.861 0.0 HOH
 7.273
 CB
 O
ALA E:303 E:313 89.0 0.774 -104.9 144.2 89.0 0.774 0.0 HOH
 3.694
 CA
 O
ALA F:303 F:313 70.0 0.609 -106.8 109.6 70.0 0.609 0.0 BH5
HOH
 9.885
5.301
 CB
N
 OAH
O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:303 A:313 85.0 0.739 -81.2 166.4 85.0 0.739 0.0 HOH
 3.964
 N
 O
ALA B:303 B:313 85.0 0.739 -98.1 139.9 85.0 0.739 0.0 HOH
 4.276
 CA
 O
ALA C:303 C:313 88.0 0.765 -95.3 168.5 88.0 0.765 0.0 HOH
 4.850
 N
 O
ALA D:303 D:313 103.0 0.896 -79.2 154.7 103.0 0.896 0.0 HOH
 5.396
 O
 O
ALA E:303 E:313 91.0 0.791 -91.4 157.2 91.0 0.791 0.0 HOH
 3.468
 CB
 O
ALA F:303 F:313 79.0 0.687 -117.2 156.1 79.0 0.687 0.0 HOH
 7.756
 O
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:303 A:313 93.0 0.809 -86.2 141.5 93.0 0.809 0.0 HOH
 5.108
 N
 O
ALA B:303 B:313 93.0 0.809 -80.3 130.7 93.0 0.809 0.0 HOH
 2.712
 O
 O
ALA C:303 C:313 98.0 0.852 -84.9 131.3 98.0 0.852 0.0 HOH
 3.008
 N
 O
ALA D:303 D:313 87.0 0.757 -97.3 136.3 87.0 0.757 0.0 HOH
 5.325
 N
 O
ALA E:303 E:313 90.0 0.783 -103.8 144.9 90.0 0.783 0.0 HOH
 3.416
 CB
 O
ALA F:303 F:313 94.0 0.817 -33.0 144.7 94.0 0.817 0.0 HOH
 5.426
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 ALA A:303 A:313 92.0 0.8 -86.3 152.8 92.0 0.8 0.0 HOH
 3.696
 CA
 O
ALA B:303 B:313 92.0 0.8 -86.8 156.0 92.0 0.8 0.0 HOH
 5.228
 O
 O
ALA C:303 C:313 96.0 0.835 S -72.2 153.2 96.0 0.835 0.0 HOH
 3.361
 CA
 O
ALA D:303 NA:NA DO NA DO DO DO NA NA NA
ALA E:303 E:313 92.0 0.8 -100.8 141.3 92.0 0.8 0.0 HOH
 3.958
 CA
 O
ALA F:303 F:313 89.0 0.774 -108.6 177.1 89.0 0.774 0.0
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 ALA A:303 A:313 94.0 0.817 -94.6 151.5 94.0 0.817 0.0 HOH
 4.652
 N
 O
ALA B:303 B:313 101.0 0.878 -75.0 138.1 101.0 0.878 0.0
ALA C:303 C:313 89.0 0.774 -76.8 173.0 89.0 0.774 0.0
ALA D:303 NA:NA DO NA DO DO DO NA NA NA
ALA E:303 E:313 92.0 0.8 -91.9 140.3 92.0 0.8 0.0
ALA F:303 F:313 82.0 0.713 -108.6 -153.7 82.0 0.713 0.0 HOH
 7.913
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 ALA A:313 A:313 76.0 0.661 -67.2 125.6