Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11689179 . G A CCDS5985.1:NM_004462.3:c.1032gaG>gaA_NP_004453.3:p.344E>E Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLU A:314 A:344 90.0 0.474 H -61.1 -46.3 90.0 0.474 0.0 HOH
 2.822
 OE2
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 GLU A:314 A:344 101.0 0.532 H -61.3 -52.4 101.0 0.532 0.0 HOH
 5.224
 OE2
 O
GLU B:314 B:344 89.0 0.468 H -46.6 -42.8 NA NA NA
GLU C:314 C:344 95.0 0.5 H -58.1 -41.9 NA NA NA
GLU D:314 D:344 76.0 0.4 H -59.2 -25.2 NA NA NA
GLU E:314 E:344 93.0 0.489 H -77.2 -28.0 NA NA NA
GLU F:314 F:344 103.0 0.542 H -47.7 -43.8 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLU A:314 A:344 93.0 0.489 H -59.0 -44.2 93.0 0.489 0.0 HOH
 2.815
 OE2
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 GLU A:314 A:344 93.0 0.489 H -62.1 -48.3 93.0 0.489 0.0 HOH
 2.605
 OE2
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 GLU A:314 A:344 93.0 0.489 H -59.9 -48.8 93.0 0.489 0.0 HOH
 2.639
 O
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLU A:317 A:344 77.0 0.405 H -56.6 -49.2 77.0 0.405 0.0 HOH
 2.385
 OE1
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLU A:317 A:344 96.0 0.505 H -66.3 -44.6 96.0 0.505 0.0 NI
HOH
 7.280
2.527
 N
OE2
 NI
O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLU A:317 A:344 89.0 0.468 H -60.8 -43.3 89.0 0.468 0.0 HOH
 2.525
 OE1
 O
GLU B:317 B:344 83.0 0.437 H -59.9 -45.7 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLU A:317 A:344 113.0 0.595 H -62.8 -43.5 113.0 0.595 0.0 HOH
 6.717
 N
 O
GLU B:317 B:344 63.0 0.332 H -57.8 -38.7 63.0 0.332 0.0 HOH
 6.283
 CG
 O
GLU C:317 C:344 46.0 0.242 H -53.6 -42.7 46.0 0.242 0.0 HOH
 5.037
 CG
 O
GLU D:317 D:344 72.0 0.379 H -58.7 -39.6 NA NA NA
GLU E:317 E:344 104.0 0.547 H -62.3 -38.2 NA NA NA
GLU F:317 F:344 91.0 0.479 H -61.5 -35.7 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 GLU A:317 A:344 26.0 0.137 H -59.8 -38.9 26.0 0.137 0.0 HOH
 2.727
 CG
 O
GLU B:317 B:344 41.0 0.216 H -61.6 -39.5 41.0 0.216 0.0 HOH
 4.546
 OE1
 O
GLU C:317 C:344 29.0 0.153 H -59.5 -38.2 29.0 0.153 0.0 HOH
 3.129
 OE2
 O
GLU D:317 D:344 48.0 0.253 H -57.6 -43.1 NA NA NA
GLU E:317 E:344 62.0 0.326 H -56.8 -40.0 NA NA NA
GLU F:317 F:344 37.0 0.195 H -59.8 -35.1 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLU A:317 A:344 73.0 0.384 H -61.7 -39.7 73.0 0.384 0.0 HOH
 5.531
 OE1
 O
GLU B:317 B:344 39.0 0.205 H -58.4 -37.1 39.0 0.205 0.0 HOH
 6.807
 N
 O
GLU C:317 C:344 33.0 0.174 H -56.8 -38.8 33.0 0.174 0.0
GLU D:317 D:344 46.0 0.242 H -52.5 -44.9 NA NA NA
GLU E:317 E:344 110.0 0.579 H -67.9 -36.0 NA NA NA
GLU F:317 F:344 77.0 0.405 H -49.9 -34.8 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLU A:317 A:344 84.0 0.442 H -60.2 -41.2 84.0 0.442 0.0 HOH
 2.823
 O
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 GLU A:317 A:344 85.0 0.447 H -61.0 -44.6 85.0 0.447 0.0 HOH
 2.510
 OE1
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLU A:317 A:344 79.0 0.416 H -63.7 -36.7 79.0 0.416 0.0 HOH
 2.755
 O
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLU A:317 A:344 84.0 0.442 H -56.1 -42.8 84.0 0.442 0.0 HOH
 2.885
 O
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 GLU A:317 A:344 81.0 0.426 H -59.2 -44.1 81.0 0.426 0.0 HOH
 2.462
 OE2
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 GLU A:314 A:344 83.0 0.437 H -59.2 -43.9 83.0 0.437 0.0 HOH
 4.724
 OE2
 O
GLU B:314 B:344 80.0 0.421 H -60.5 -51.6 NA NA NA
GLU C:314 C:344 65.0 0.342 H -63.7 -45.6 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLU A:334 A:344 50.0 0.263 H -58.1 -41.2 50.0 0.263 0.0 HOH
 3.768
 OE1
 O
GLU B:334 B:344 26.0 0.137 H -57.0 -29.9 26.0 0.137 0.0 HOH
 3.450
 OE1
 O
GLU C:334 C:344 41.0 0.216 H -54.2 -45.9 41.0 0.216 0.0 HOH
 6.065
 OE2
 O
GLU D:334 D:344 61.0 0.321 H -56.6 -19.9 61.0 0.321 0.0 HOH
 7.187
 OE2
 O
GLU E:334 E:344 53.0 0.279 H -65.6 -25.9 53.0 0.279 0.0 HOH
 4.485
 CD
 O
GLU F:334 F:344 38.0 0.2 H -51.8 -30.7 38.0 0.2 0.0 HOH
 7.103
 O
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLU A:334 A:344 42.0 0.221 H -54.6 -42.8 42.0 0.221 0.0 HOH
 2.519
 OE1
 O
GLU B:334 B:344 51.0 0.268 H -51.1 -29.5 51.0 0.268 0.0 HOH
 3.303
 OE1
 O
GLU C:334 C:344 43.0 0.226 H -61.8 -33.7 43.0 0.226 0.0 HOH
 8.943
 N
 O
GLU D:334 D:344 67.0 0.353 H -70.0 -20.8 67.0 0.353 0.0 HOH
 8.568
 OE1
 O
GLU E:334 E:344 36.0 0.189 H -62.7 -32.8 36.0 0.189 0.0 HOH
 3.360
 OE2
 O
GLU F:334 F:344 41.0 0.216 H -56.5 -40.2 41.0 0.216 0.0 HOH
 5.065
 N
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLU A:334 A:344 65.0 0.342 H -61.2 -41.2 65.0 0.342 0.0 HOH
 5.880
 CG
 O
GLU B:334 B:344 38.0 0.2 H -70.5 -29.8 38.0 0.2 0.0 HOH
 8.969
 N
 O
GLU C:334 C:344 76.0 0.4 H -55.4 -41.1 76.0 0.4 0.0 HOH
 6.142
 N
 O
GLU D:334 D:344 48.0 0.253 H -57.6 -36.7 48.0 0.253 0.0
GLU E:334 E:344 37.0 0.195 H -65.3 -32.9 37.0 0.195 0.0 HOH
 9.420
 N
 O
GLU F:334 F:344 42.0 0.221 H -61.2 -29.7 42.0 0.221 0.0 HOH
 5.712
 CG
 O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLU A:334 A:344 38.0 0.2 H -59.9 -35.9 38.0 0.2 0.0 HOH
 6.813
 N
 O
GLU B:334 B:344 51.0 0.268 H -63.7 -33.9 51.0 0.268 0.0
GLU C:334 C:344 60.0 0.316 H -59.4 -40.5 60.0 0.316 0.0 HOH
 6.259
 CG
 O
GLU D:334 D:344 50.0 0.263 H -50.3 -35.5 50.0 0.263 0.0 HOH
 2.969
 CG
 O
GLU E:334 E:344 45.0 0.237 H -62.8 -45.6 45.0 0.237 0.0 HOH
 3.166
 OE2
 O
GLU F:334 F:344 73.0 0.384 H -52.1 -29.9 73.0 0.384 0.0 HOH
 3.113
 OE2
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLU A:334 A:344 57.0 0.3 H -61.3 -37.9 57.0 0.3 0.0 HOH
 3.981
 N
 O
GLU B:334 B:344 40.0 0.211 H -57.4 -31.7 40.0 0.211 0.0 HOH
 4.406
 OE2
 O
GLU C:334 C:344 66.0 0.347 H -60.5 -36.0 66.0 0.347 0.0 HOH
 3.497
 OE1
 O
GLU D:334 D:344 53.0 0.279 H -53.2 -38.6 53.0 0.279 0.0 HOH
 2.985
 CG
 O
GLU E:334 E:344 38.0 0.2 H -59.5 -35.3 38.0 0.2 0.0 HOH
 2.818
 OE2
 O
GLU F:334 F:344 60.0 0.316 H -59.9 -34.3 60.0 0.316 0.0 HOH
 4.349
 OE1
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLU A:334 A:344 27.0 0.142 H -60.9 -40.8 27.0 0.142 0.0 HOH
 5.227
 CD
 O
GLU B:334 B:344 74.0 0.389 H -63.9 -39.6 74.0 0.389 0.0 HOH
 4.254
 OE1
 O
GLU C:334 C:344 41.0 0.216 H -59.3 -36.8 41.0 0.216 0.0 HOH
 3.536
 OE1
 O
GLU D:334 D:344 52.0 0.274 H -58.2 -34.9 52.0 0.274 0.0 HOH
 5.152
 OE2
 O
GLU E:334 E:344 36.0 0.189 H -69.8 -36.8 36.0 0.189 0.0 HOH
 4.432
 OE1
 O
GLU F:334 F:344 34.0 0.179 H -66.6 -29.8 34.0 0.179 0.0 HOH
 4.066
 OE1
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLU A:334 A:344 78.0 0.411 H -61.2 -42.5 78.0 0.411 0.0 HOH
 3.036
 OE2
 O
GLU B:334 B:344 45.0 0.237 H -70.6 -24.6 45.0 0.237 0.0 HOH
 3.008
 OE2
 O
GLU C:334 C:344 67.0 0.353 H -58.6 -36.4 67.0 0.353 0.0 HOH
 2.923
 OE1
 O
GLU D:334 D:344 47.0 0.247 H -64.6 -40.5 47.0 0.247 0.0 HOH
 2.791
 OE2
 O
GLU E:334 E:344 39.0 0.205 H -62.8 -39.3 39.0 0.205 0.0 HOH
 3.861
 CG
 O
GLU F:334 F:344 57.0 0.3 H -59.1 -31.5 57.0 0.3 0.0 HOH
 7.075
 N
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 GLU A:334 A:344 84.0 0.442 H -57.6 -41.5 84.0 0.442 0.0 HOH
 2.879
 O
 O
GLU B:334 B:344 66.0 0.347 H -63.9 -33.4 66.0 0.347 0.0 HOH
 3.686
 OE1
 O
GLU C:334 C:344 78.0 0.411 H -59.3 -38.2 78.0 0.411 0.0 HOH
 2.700
 O
 O
GLU D:334 D:344 73.0 0.384 H -61.8 -39.1 73.0 0.384 0.0 HOH
 3.997
 OE2
 O
GLU E:334 E:344 87.0 0.458 H -69.0 -40.9 87.0 0.458 0.0 HOH
 4.073
 OE1
 O
GLU F:334 F:344 83.0 0.437 H -62.4 -36.7 83.0 0.437 0.0 HOH
 4.599
 OE1
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 GLU A:334 A:344 90.0 0.474 H -63.9 -46.1 90.0 0.474 0.0 HOH
 5.262
 OE1
 O
GLU B:334 B:344 93.0 0.489 H -81.0 -3.7 93.0 0.489 0.0 HOH
 3.015
 OE1
 O
GLU C:334 C:344 68.0 0.358 H -51.5 -51.4 68.0 0.358 0.0
GLU D:334 D:344 88.0 0.463 H -56.6 -34.0 88.0 0.463 0.0 HOH
 4.886
 OE2
 O
GLU E:334 E:344 95.0 0.5 H -63.9 -34.9 95.0 0.5 0.0 HOH
 5.631
 OE2
 O
GLU F:334 F:344 92.0 0.484 H -62.5 -19.3 92.0 0.484 0.0 HOH
 3.275
 OE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 GLU A:344 A:344 72.0 0.379 H -61.1 -34.6