Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11695928 . C A CCDS5985.1:NM_004462.3:c.1064tCt>tAt_NP_004453.3:p.355S>Y Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:325 A:355 3.0 0.026 T -102.6 7.4 3.0 0.026 0.0 HOH
 2.606
 OG
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 SER A:325 A:355 1.0 0.009 T -122.3 36.9 1.0 0.009 0.0 HOH
 4.774
 CB
 O
SER B:325 B:355 16.0 0.139 T -116.5 35.3 NA NA NA
SER C:325 C:355 17.0 0.148 T -103.6 -3.8 NA NA NA
SER D:325 D:355 12.0 0.104 T -88.3 34.3 NA NA NA
SER E:325 E:355 1.0 0.009 T -111.2 6.4 NA NA NA
SER F:325 F:355 52.0 0.452 T -110.6 18.3 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:325 A:355 2.0 0.017 T -98.9 1.8 2.0 0.017 0.0 HOH
 2.594
 OG
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:325 A:355 4.0 0.035 T -109.0 8.2 4.0 0.035 0.0 HOH
 2.710
 OG
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 SER A:325 A:355 2.0 0.017 T -99.5 8.2 2.0 0.017 0.0 HOH
 2.719
 OG
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:328 A:355 2.0 0.017 T -99.3 3.2 2.0 0.017 0.0 HOH
 2.670
 OG
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:328 A:355 14.0 0.122 T -96.6 3.7 14.0 0.122 0.0 HOH
 2.630
 OG
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:328 A:355 16.0 0.139 T -96.5 6.3 16.0 0.139 0.0 HOH
 2.716
 OG
 O
SER B:328 B:355 14.0 0.122 T -91.9 -2.5 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:328 A:355 15.0 0.13 T -99.2 4.7 15.0 0.13 0.0 HOH
 2.686
 OG
 O
SER B:328 B:355 4.0 0.035 T -92.0 3.5 4.0 0.035 0.0 HOH
 2.512
 OG
 O
SER C:328 C:355 14.0 0.122 T -105.5 4.2 14.0 0.122 0.0 HOH
 2.818
 OG
 O
SER D:328 D:355 3.0 0.026 T -113.2 10.2 NA NA NA
SER E:328 E:355 13.0 0.113 T -102.0 2.1 NA NA NA
SER F:328 F:355 11.0 0.096 T -111.6 -14.3 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:328 A:355 7.0 0.061 T -97.7 5.6 7.0 0.061 0.0 HOH
 2.662
 OG
 O
SER B:328 B:355 6.0 0.052 T -95.1 4.9 6.0 0.052 0.0 HOH
 2.802
 OG
 O
SER C:328 C:355 4.0 0.035 T -97.1 2.8 4.0 0.035 0.0 HOH
 2.642
 OG
 O
SER D:328 D:355 2.0 0.017 T -104.3 3.1 NA NA NA
SER E:328 E:355 13.0 0.113 T -98.0 -1.6 NA NA NA
SER F:328 F:355 2.0 0.017 T -92.4 2.8 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:328 A:355 5.0 0.043 T -100.7 9.3 5.0 0.043 0.0 HOH
 2.822
 OG
 O
SER B:328 B:355 5.0 0.043 T -96.4 8.1 5.0 0.043 0.0 HOH
 9.025
 C
 O
SER C:328 C:355 3.0 0.026 T -104.4 -0.1 3.0 0.026 0.0 HOH
 3.551
 CB
 O
SER D:328 D:355 2.0 0.017 T -105.0 7.2 NA NA NA
SER E:328 E:355 22.0 0.191 T -151.1 -4.9 NA NA NA
SER F:328 F:355 15.0 0.13 T -107.0 5.6 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:328 A:355 13.0 0.113 T -97.9 3.7 13.0 0.113 0.0 HOH
 2.743
 OG
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:328 A:355 10.0 0.087 T -101.7 4.1 10.0 0.087 0.0 HOH
 2.570
 OG
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:328 A:355 15.0 0.13 T -102.0 7.9 15.0 0.13 0.0 HOH
 2.315
 OG
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:328 A:355 12.0 0.104 T -98.8 1.2 12.0 0.104 0.0 HOH
 2.658
 OG
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:328 A:355 2.0 0.017 T -95.3 -1.9 2.0 0.017 0.0 HOH
 2.878
 OG
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 SER A:325 A:355 0.0 0.0 T -102.4 0.9 0.0 0.0 0.0 HOH
 2.807
 OG
 O
SER B:325 B:355 0.0 0.0 T -103.0 -13.1 NA NA NA
SER C:325 C:355 5.0 0.043 T -106.6 1.1 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:345 A:355 5.0 0.043 T -110.2 11.4 5.0 0.043 0.0 HOH
 5.259
 CB
 O
SER B:345 B:355 1.0 0.009 T -117.6 8.0 1.0 0.009 0.0 HOH
 6.390
 CB
 O
SER C:345 C:355 4.0 0.035 T -93.6 14.4 4.0 0.035 0.0 HOH
 5.266
 CB
 O
SER D:345 D:355 1.0 0.009 T -95.4 -11.5 1.0 0.009 0.0 HOH
 9.598
 CB
 O
SER E:345 E:355 0.0 0.0 T -102.0 6.9 0.0 0.0 0.0 HOH
 8.850
 OG
 O
SER F:345 F:355 0.0 0.0 T -104.7 -4.7 0.0 0.0 0.0 HOH
 5.964
 OG
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:345 A:355 9.0 0.078 T -113.8 14.6 9.0 0.078 0.0 HOH
 3.720
 C
 O
SER B:345 B:355 3.0 0.026 T -107.7 4.6 3.0 0.026 0.0 HOH
 9.150
 OG
 O
SER C:345 C:355 7.0 0.061 T -98.8 -10.5 7.0 0.061 0.0 HOH
 5.862
 OG
 O
SER D:345 D:355 2.0 0.017 S -90.2 -7.8 2.0 0.017 0.0 HOH
 9.829
 O
 O
SER E:345 E:355 1.0 0.009 T -97.9 -8.0 1.0 0.009 0.0 HOH
 5.824
 OG
 O
SER F:345 F:355 1.0 0.009 T -73.1 -0.5 1.0 0.009 0.0 HOH
 5.567
 N
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:345 A:355 2.0 0.017 T -111.3 3.3 2.0 0.017 0.0 HOH
 2.675
 OG
 O
SER B:345 B:355 3.0 0.026 T -102.2 -13.4 3.0 0.026 0.0
SER C:345 C:355 2.0 0.017 T -106.9 -4.0 2.0 0.017 0.0 HOH
 2.575
 OG
 O
SER D:345 D:355 1.0 0.009 T -94.6 -12.8 1.0 0.009 0.0 HOH
 4.779
 OG
 O
SER E:345 E:355 2.0 0.017 T -108.5 2.6 2.0 0.017 0.0 HOH
 5.005
 OG
 O
SER F:345 F:355 1.0 0.009 S -113.3 -16.4 1.0 0.009 0.0
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:345 A:355 1.0 0.009 T -121.5 0.9 1.0 0.009 0.0 HOH
 2.903
 OG
 O
SER B:345 B:355 1.0 0.009 T -110.3 -16.5 1.0 0.009 0.0
SER C:345 C:355 2.0 0.017 T -98.4 -5.1 2.0 0.017 0.0 HOH
 5.573
 OG
 O
SER D:345 D:355 0.0 0.0 T -98.6 10.2 0.0 0.0 0.0
SER E:345 E:355 0.0 0.0 T -118.9 3.8 0.0 0.0 0.0 HOH
 5.347
 OG
 O
SER F:345 F:355 5.0 0.043 T -98.9 -19.6 5.0 0.043 0.0
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:345 A:355 5.0 0.043 T -107.4 7.0 5.0 0.043 0.0 HOH
 2.918
 OG
 O
SER B:345 B:355 2.0 0.017 T -113.3 -6.8 2.0 0.017 0.0 HOH
 4.106
 O
 O
SER C:345 C:355 3.0 0.026 T -108.9 -3.4 3.0 0.026 0.0 HOH
 2.669
 OG
 O
SER D:345 D:355 1.0 0.009 T -91.2 -7.9 1.0 0.009 0.0 HOH
 3.843
 CB
 O
SER E:345 E:355 2.0 0.017 T -104.4 0.3 2.0 0.017 0.0 HOH
 4.683
 C
 O
SER F:345 F:355 1.0 0.009 T -120.0 -4.6 1.0 0.009 0.0 HOH
 8.627
 N
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:345 A:355 4.0 0.035 T -102.0 -1.0 4.0 0.035 0.0 HOH
 2.801
 OG
 O
SER B:345 B:355 2.0 0.017 T -103.5 -11.7 2.0 0.017 0.0 HOH
 5.078
 OG
 O
SER C:345 C:355 4.0 0.035 T -105.6 7.3 4.0 0.035 0.0 HOH
 2.630
 OG
 O
SER D:345 D:355 1.0 0.009 T -103.4 -3.3 1.0 0.009 0.0 HOH
 9.063
 C
 O
SER E:345 E:355 2.0 0.017 T -106.7 -1.4 2.0 0.017 0.0 HOH
 2.771
 OG
 O
SER F:345 F:355 0.0 0.0 S -101.4 -28.7 0.0 0.0 0.0 HOH
 6.987
 O
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:345 A:355 2.0 0.017 T -106.1 7.8 2.0 0.017 0.0 HOH
 2.719
 OG
 O
SER B:345 B:355 2.0 0.017 T -101.1 -14.1 2.0 0.017 0.0 HOH
 3.685
 CB
 O
SER C:345 C:355 4.0 0.035 T -95.6 -2.0 4.0 0.035 0.0 HOH
 2.584
 OG
 O
SER D:345 D:355 0.0 0.0 T -96.2 0.6 0.0 0.0 0.0 HOH
 3.469
 C
 O
SER E:345 E:355 6.0 0.052 T -105.6 2.2 6.0 0.052 0.0 HOH
 2.610
 OG
 O
SER F:345 F:355 1.0 0.009 T -116.8 -8.6 1.0 0.009 0.0 HOH
 4.892
 OG
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:345 A:355 4.0 0.035 T -105.9 -3.5 4.0 0.035 0.0 HOH
 2.676
 OG
 O
SER B:345 B:355 2.0 0.017 T -105.3 -0.6 2.0 0.017 0.0 HOH
 3.539
 CB
 O
SER C:345 C:355 4.0 0.035 T -100.7 1.6 4.0 0.035 0.0 HOH
 2.799
 OG
 O
SER D:345 D:355 1.0 0.009 T -104.8 -2.9 1.0 0.009 0.0 HOH
 7.028
 OG
 O
SER E:345 E:355 1.0 0.009 T -110.8 1.0 1.0 0.009 0.0 HOH
 2.810
 OG
 O
SER F:345 F:355 0.0 0.0 T -109.2 -15.6 0.0 0.0 0.0 HOH
 3.725
 CB
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 SER A:345 A:355 8.0 0.07 T -126.3 -5.4 8.0 0.07 0.0 HOH
 4.287
 OG
 O
SER B:345 B:355 2.0 0.017 T -100.6 -12.8 2.0 0.017 0.0
SER C:345 C:355 1.0 0.009 T -92.1 -14.6 1.0 0.009 0.0 HOH
 8.484
 OG
 O
SER D:345 D:355 0.0 0.0 T -87.4 -7.0 0.0 0.0 0.0
SER E:345 E:355 1.0 0.009 T -104.6 18.5 1.0 0.009 0.0
SER F:345 F:355 1.0 0.009 T -123.7 -7.9 1.0 0.009 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 SER A:355 A:355 9.0 0.078 T -87.7 -10.0