Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11695931 . C A CCDS5985.1:NM_004462.3:c.1067tCt>tAt_NP_004453.3:p.356S>Y Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:326 A:356 17.0 0.148 H -56.2 -45.5 17.0 0.148 0.0 HOH
 2.934
 OG
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 SER A:326 A:356 11.0 0.096 H -68.7 -49.0 11.0 0.096 0.0 HOH
 7.309
 N
 O
SER B:326 B:356 8.0 0.07 H -78.6 -40.3 NA NA NA
SER C:326 C:356 17.0 0.148 H -36.7 -57.6 NA NA NA
SER D:326 D:356 10.0 0.087 H -71.0 -50.4 NA NA NA
SER E:326 E:356 13.0 0.113 H -34.1 -49.7 NA NA NA
SER F:326 F:356 22.0 0.191 H -64.3 -65.1 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:326 A:356 15.0 0.13 H -53.4 -48.7 15.0 0.13 0.0 HOH
 3.607
 CA
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:326 A:356 16.0 0.139 H -64.5 -37.0 16.0 0.139 0.0 HOH
 3.172
 OG
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 SER A:326 A:356 20.0 0.174 H -53.4 -49.0 20.0 0.174 0.0 HOH
 2.546
 OG
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:329 A:356 17.0 0.148 H -51.8 -46.2 17.0 0.148 0.0 HOH
 3.114
 OG
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:329 A:356 14.0 0.122 H -53.6 -47.7 14.0 0.122 0.0 HOH
 2.914
 OG
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:329 A:356 12.0 0.104 H -53.2 -44.6 12.0 0.104 0.0 HOH
 2.814
 OG
 O
SER B:329 B:356 12.0 0.104 H -55.5 -44.3 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:329 A:356 12.0 0.104 H -54.8 -45.8 12.0 0.104 0.0 HOH
 2.750
 OG
 O
SER B:329 B:356 11.0 0.096 H -59.7 -39.0 11.0 0.096 0.0 HOH
 2.332
 OG
 O
SER C:329 C:356 11.0 0.096 H -57.0 -42.3 11.0 0.096 0.0 HOH
 3.403
 OG
 O
SER D:329 D:356 15.0 0.13 H -53.2 -44.5 NA NA NA
SER E:329 E:356 18.0 0.157 H -46.6 -52.8 NA NA NA
SER F:329 F:356 14.0 0.122 H -38.1 -50.1 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:329 A:356 16.0 0.139 H -55.2 -46.9 16.0 0.139 0.0 HOH
 2.998
 OG
 O
SER B:329 B:356 12.0 0.104 H -52.6 -46.2 12.0 0.104 0.0 HOH
 2.523
 OG
 O
SER C:329 C:356 14.0 0.122 H -57.9 -44.3 14.0 0.122 0.0 HOH
 2.927
 OG
 O
SER D:329 D:356 14.0 0.122 H -48.7 -45.0 NA NA NA
SER E:329 E:356 15.0 0.13 H -43.7 -47.2 NA NA NA
SER F:329 F:356 13.0 0.113 H -49.0 -40.4 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:329 A:356 15.0 0.13 H -54.4 -52.5 15.0 0.13 0.0 HOH
 3.755
 N
 O
SER B:329 B:356 11.0 0.096 H -62.6 -45.2 11.0 0.096 0.0 HOH
 5.525
 OG
 O
SER C:329 C:356 8.0 0.07 H -37.7 -49.6 8.0 0.07 0.0 HOH
 3.702
 N
 O
SER D:329 D:356 15.0 0.13 H -52.7 -49.8 NA NA NA
SER E:329 E:356 12.0 0.104 H -42.2 -43.7 NA NA NA
SER F:329 F:356 7.0 0.061 H -38.1 -50.5 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:329 A:356 11.0 0.096 H -55.3 -43.0 11.0 0.096 0.0 HOH
 2.843
 OG
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:329 A:356 13.0 0.113 H -56.1 -44.1 13.0 0.113 0.0 HOH
 3.673
 N
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:329 A:356 13.0 0.113 H -54.6 -42.6 13.0 0.113 0.0 HOH
 2.729
 OG
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:329 A:356 13.0 0.113 H -53.1 -45.6 13.0 0.113 0.0 HOH
 2.966
 OG
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:329 A:356 19.0 0.165 H -50.2 -48.7 19.0 0.165 0.0 HOH
 3.085
 OG
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 SER A:326 A:356 3.0 0.026 H -36.9 -54.0 3.0 0.026 0.0 HOH
 3.842
 N
 O
SER B:326 B:356 15.0 0.13 H -31.0 -40.8 NA NA NA
SER C:326 C:356 15.0 0.13 H -44.5 -47.3 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:346 A:356 10.0 0.087 H -41.7 -66.3 10.0 0.087 0.0 HOH
 3.154
 CB
 O
SER B:346 B:356 12.0 0.104 H -49.9 -34.0 12.0 0.104 0.0 HOH
 5.196
 OG
 O
SER C:346 C:356 10.0 0.087 H -48.8 -44.4 10.0 0.087 0.0 HOH
 7.232
 N
 O
SER D:346 D:356 15.0 0.13 H -35.6 -42.7 15.0 0.13 0.0 HOH
 8.257
 O
 O
SER E:346 E:356 19.0 0.165 H -32.8 -57.3 19.0 0.165 0.0 HOH
 9.486
 N
 O
SER F:346 F:356 10.0 0.087 T -58.9 -166.6 10.0 0.087 0.0 HOH
 8.689
 OG
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:346 A:356 12.0 0.104 H -48.2 -44.9 12.0 0.104 0.0 HOH
 3.889
 N
 O
SER B:346 B:356 13.0 0.113 H -46.4 -37.7 13.0 0.113 0.0 HOH
 7.511
 O
 O
SER C:346 C:356 10.0 0.087 H -31.3 -44.3 10.0 0.087 0.0 HOH
 7.165
 O
 O
SER D:346 D:356 11.0 0.096 H -40.3 -30.1 11.0 0.096 0.0 HOH
 6.706
 O
 O
SER E:346 E:356 13.0 0.113 H -39.5 -37.8 13.0 0.113 0.0 HOH
 7.648
 O
 O
SER F:346 F:356 13.0 0.113 T -61.8 -175.5 13.0 0.113 0.0 HOH
 3.437
 OG
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:346 A:356 13.0 0.113 H -44.2 -52.4 13.0 0.113 0.0 HOH
 3.777
 N
 O
SER B:346 B:356 16.0 0.139 H -30.8 -48.2 16.0 0.139 0.0
SER C:346 C:356 10.0 0.087 H -43.5 -49.6 10.0 0.087 0.0 HOH
 5.293
 N
 O
SER D:346 D:356 15.0 0.13 H -32.5 -52.9 15.0 0.13 0.0 HOH
 8.236
 N
 O
SER E:346 E:356 13.0 0.113 H -37.1 -48.5 13.0 0.113 0.0 HOH
 5.965
 OG
 O
SER F:346 F:356 12.0 0.104 H -28.5 -57.7 12.0 0.104 0.0 HOH
 8.976
 O
 O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:346 A:356 12.0 0.104 H -44.2 -46.6 12.0 0.104 0.0 HOH
 6.715
 N
 O
SER B:346 B:356 13.0 0.113 H -30.6 -47.5 13.0 0.113 0.0
SER C:346 C:356 10.0 0.087 H -40.5 -45.2 10.0 0.087 0.0 HOH
 9.026
 N
 O
SER D:346 D:356 13.0 0.113 H -48.4 -45.1 13.0 0.113 0.0
SER E:346 E:356 12.0 0.104 H -47.3 -45.4 12.0 0.104 0.0 HOH
 7.844
 O
 O
SER F:346 F:356 16.0 0.139 H -29.3 -52.3 16.0 0.139 0.0 HOH
 8.250
 O
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:346 A:356 13.0 0.113 H -43.7 -47.5 13.0 0.113 0.0 HOH
 2.687
 OG
 O
SER B:346 B:356 15.0 0.13 H -39.7 -33.0 15.0 0.13 0.0 HOH
 3.017
 OG
 O
SER C:346 C:356 10.0 0.087 H -41.2 -47.3 10.0 0.087 0.0 HOH
 3.552
 N
 O
SER D:346 D:356 14.0 0.122 H -42.2 -38.7 14.0 0.122 0.0 HOH
 4.074
 N
 O
SER E:346 E:356 12.0 0.104 H -46.5 -38.4 12.0 0.104 0.0 HOH
 2.771
 OG
 O
SER F:346 F:356 10.0 0.087 H -39.3 -51.6 10.0 0.087 0.0 HOH
 9.235
 O
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:346 A:356 14.0 0.122 H -38.8 -52.6 14.0 0.122 0.0 HOH
 2.598
 OG
 O
SER B:346 B:356 11.0 0.096 H -31.1 -47.9 11.0 0.096 0.0 HOH
 7.725
 O
 O
SER C:346 C:356 7.0 0.061 H -45.9 -49.2 7.0 0.061 0.0 HOH
 3.860
 N
 O
SER D:346 D:356 14.0 0.122 H -37.3 -49.1 14.0 0.122 0.0 HOH
 5.292
 OG
 O
SER E:346 E:356 15.0 0.13 H -41.9 -49.2 15.0 0.13 0.0 HOH
 5.411
 N
 O
SER F:346 F:356 7.0 0.061 H -30.0 -57.5 7.0 0.061 0.0 HOH
 4.699
 O
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:346 A:356 15.0 0.13 H -47.2 -50.3 15.0 0.13 0.0 HOH
 2.756
 OG
 O
SER B:346 B:356 12.0 0.104 H -30.9 -46.0 12.0 0.104 0.0 HOH
 2.593
 OG
 O
SER C:346 C:356 11.0 0.096 H -38.8 -55.1 11.0 0.096 0.0 HOH
 3.718
 OG
 O
SER D:346 D:356 14.0 0.122 H -51.2 -42.6 14.0 0.122 0.0 HOH
 3.580
 N
 O
SER E:346 E:356 14.0 0.122 H -38.9 -54.3 14.0 0.122 0.0 HOH
 3.707
 N
 O
SER F:346 F:356 11.0 0.096 H -35.9 -50.7 11.0 0.096 0.0 HOH
 4.954
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:346 A:356 14.0 0.122 H -38.3 -53.1 14.0 0.122 0.0 HOH
 2.773
 OG
 O
SER B:346 B:356 19.0 0.165 H -37.7 -63.0 19.0 0.165 0.0 HOH
 3.586
 N
 O
SER C:346 C:356 8.0 0.07 H -44.0 -51.1 8.0 0.07 0.0 HOH
 2.590
 OG
 O
SER D:346 D:356 18.0 0.157 H -33.9 -54.5 18.0 0.157 0.0 HOH
 4.901
 C
 O
SER E:346 E:356 13.0 0.113 H -41.7 -52.0 13.0 0.113 0.0 HOH
 3.992
 N
 O
SER F:346 F:356 15.0 0.13 H -29.1 -52.7 15.0 0.13 0.0 HOH
 3.868
 N
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 SER A:346 A:356 8.0 0.07 H -41.4 -46.5 8.0 0.07 0.0 HOH
 6.860
 O
 O
SER B:346 B:356 10.0 0.087 H -28.3 -74.8 10.0 0.087 0.0 HOH
 8.237
 OG
 O
SER C:346 C:356 9.0 0.078 H -35.0 -50.8 9.0 0.078 0.0
SER D:346 D:356 14.0 0.122 H -38.7 -46.4 14.0 0.122 0.0
SER E:346 E:356 11.0 0.096 H -68.4 -42.1 11.0 0.096 0.0
SER F:346 F:356 17.0 0.148 H -40.9 -48.8 17.0 0.148 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 SER A:356 A:356 13.0 0.113 H -46.8 -49.1