Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11695935 . C A CCDS5985.1:NM_004462.3:c.1071agC>agA_NP_004453.3:p.357S>R Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:327 A:357 86.0 0.748 H -74.8 -24.9 86.0 0.748 0.0 HOH
 2.880
 N
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 SER A:327 A:357 81.0 0.704 H -58.1 -43.4 81.0 0.704 0.0 HOH
 8.460
 OG
 O
SER B:327 B:357 82.0 0.713 H -65.4 -55.1 NA NA NA
SER C:327 C:357 82.0 0.713 H -56.9 -42.5 NA NA NA
SER D:327 D:357 82.0 0.713 H -63.6 -38.9 NA NA NA
SER E:327 E:357 86.0 0.748 H -87.6 -35.5 NA NA NA
SER F:327 F:357 72.0 0.626 H -63.0 -29.3 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:327 A:357 81.0 0.704 H -71.7 -27.5 81.0 0.704 0.0 HOH
 5.787
 N
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 SER A:327 A:357 86.0 0.748 H -71.7 -28.9 86.0 0.748 0.0 HOH
 2.920
 OG
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 SER A:327 A:357 85.0 0.739 H -65.9 -37.3 85.0 0.739 0.0 HOH
 2.743
 N
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:330 A:357 90.0 0.783 H -59.0 -48.0 90.0 0.783 0.0 HOH
 2.860
 O
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:330 A:357 73.0 0.635 H -57.4 -45.4 73.0 0.635 0.0 HOH
 3.033
 N
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:330 A:357 89.0 0.774 H -62.5 -42.2 89.0 0.774 0.0 HOH
 2.529
 O
 O
SER B:330 B:357 87.0 0.757 H -61.7 -44.9 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:330 A:357 77.0 0.67 H -62.5 -44.7 77.0 0.67 0.0 HOH
 2.797
 OG
 O
SER B:330 B:357 82.0 0.713 H -63.9 -41.6 82.0 0.713 0.0 HOH
 3.779
 N
 O
SER C:330 C:357 94.0 0.817 H -56.4 -46.0 94.0 0.817 0.0 HOH
 5.054
 N
 O
SER D:330 D:357 91.0 0.791 H -60.3 -43.2 NA NA NA
SER E:330 E:357 82.0 0.713 H -61.9 -44.4 NA NA NA
SER F:330 F:357 89.0 0.774 H -59.4 -46.1 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 SER A:330 A:357 76.0 0.661 H -65.3 -32.9 76.0 0.661 0.0 HOH
 2.882
 OG
 O
SER B:330 B:357 76.0 0.661 H -64.1 -39.7 76.0 0.661 0.0 HOH
 2.906
 O
 O
SER C:330 C:357 79.0 0.687 H -58.4 -42.4 79.0 0.687 0.0 HOH
 3.435
 CB
 O
SER D:330 D:357 84.0 0.73 H -62.2 -44.9 NA NA NA
SER E:330 E:357 79.0 0.687 H -67.0 -44.4 NA NA NA
SER F:330 F:357 73.0 0.635 H -65.7 -47.6 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:330 A:357 74.0 0.643 H -56.0 -42.1 74.0 0.643 0.0 HOH
 5.925
 N
 O
SER B:330 B:357 86.0 0.748 H -57.9 -43.3 86.0 0.748 0.0 HOH
 4.443
 OG
 O
SER C:330 C:357 91.0 0.791 H -76.0 -35.9 91.0 0.791 0.0 HOH
 5.955
 N
 O
SER D:330 D:357 83.0 0.722 H -62.3 -38.7 NA NA NA
SER E:330 E:357 73.0 0.635 H -65.3 -44.6 NA NA NA
SER F:330 F:357 61.0 0.53 H -60.8 -50.9 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:330 A:357 75.0 0.652 H -62.1 -46.6 75.0 0.652 0.0 HOH
 2.605
 OG
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 SER A:330 A:357 91.0 0.791 H -56.6 -49.1 91.0 0.791 0.0 HOH
 3.410
 CB
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:330 A:357 77.0 0.67 H -61.9 -47.2 77.0 0.67 0.0 HOH
 2.718
 OG
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:330 A:357 83.0 0.722 H -59.3 -44.1 83.0 0.722 0.0 HOH
 2.667
 OG
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 SER A:330 A:357 87.0 0.757 H -59.7 -44.2 87.0 0.757 0.0 HOH
 3.203
 N
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 SER A:327 A:357 90.0 0.783 H -63.3 -42.5 90.0 0.783 0.0 HOH
 3.344
 OG
 O
SER B:327 B:357 85.0 0.739 H -69.5 -48.9 NA NA NA
SER C:327 C:357 65.0 0.565 H -62.2 -39.5 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:347 A:357 86.0 0.748 H -60.1 -32.1 86.0 0.748 0.0 HOH
 3.118
 OG
 O
SER B:347 B:357 86.0 0.748 H -79.8 -16.1 86.0 0.748 0.0 HOH
 2.881
 OG
 O
SER C:347 C:357 75.0 0.652 H -70.8 -35.4 75.0 0.652 0.0 HOH
 5.340
 OG
 O
SER D:347 D:357 85.0 0.739 H -71.9 -49.7 85.0 0.739 0.0 HOH
 7.380
 O
 O
SER E:347 E:357 77.0 0.67 H -75.4 -23.7 77.0 0.67 0.0 HOH
 7.666
 O
 O
SER F:347 F:357 75.0 0.652 T 62.4 -69.8 75.0 0.652 0.0 HOH
 7.621
 O
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:347 A:357 72.0 0.626 H -71.7 -44.7 72.0 0.626 0.0 HOH
 4.958
 O
 O
SER B:347 B:357 92.0 0.8 H -76.3 -32.5 92.0 0.8 0.0 HOH
 7.792
 OG
 O
SER C:347 C:357 79.0 0.687 H -74.8 -33.6 79.0 0.687 0.0 HOH
 6.120
 OG
 O
SER D:347 D:357 64.0 0.557 H -72.2 -69.6 64.0 0.557 0.0 HOH
 6.311
 O
 O
SER E:347 E:357 88.0 0.765 H -69.6 -30.7 88.0 0.765 0.0 HOH
 5.869
 O
 O
SER F:347 F:357 78.0 0.678 T 70.5 -46.2 78.0 0.678 0.0 HOH
 6.207
 CB
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:347 A:357 85.0 0.739 H -62.4 -47.1 85.0 0.739 0.0 HOH
 3.179
 OG
 O
SER B:347 B:357 85.0 0.739 H -73.1 -28.7 85.0 0.739 0.0
SER C:347 C:357 84.0 0.73 H -63.6 -43.3 84.0 0.73 0.0 HOH
 8.014
 N
 O
SER D:347 D:357 87.0 0.757 H -65.0 -43.5 87.0 0.757 0.0 HOH
 9.040
 C
 O
SER E:347 E:357 89.0 0.774 H -69.4 -41.4 89.0 0.774 0.0 HOH
 8.270
 N
 O
SER F:347 F:357 84.0 0.73 H -60.4 -37.2 84.0 0.73 0.0 HOH
 7.837
 O
 O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:347 A:357 80.0 0.696 H -59.5 -56.3 80.0 0.696 0.0 HOH
 3.048
 OG
 O
SER B:347 B:357 77.0 0.67 H -64.1 -41.9 77.0 0.67 0.0
SER C:347 C:357 71.0 0.617 H -63.4 -46.2 71.0 0.617 0.0 HOH
 7.005
 O
 O
SER D:347 D:357 80.0 0.696 H -71.3 -42.9 80.0 0.696 0.0
SER E:347 E:357 91.0 0.791 H -61.6 -51.5 91.0 0.791 0.0 HOH
 5.798
 O
 O
SER F:347 F:357 70.0 0.609 H -56.0 -50.5 70.0 0.609 0.0 HOH
 7.267
 O
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:347 A:357 74.0 0.643 H -65.7 -49.6 74.0 0.643 0.0 HOH
 2.958
 N
 O
SER B:347 B:357 86.0 0.748 H -80.8 -37.6 86.0 0.748 0.0 HOH
 3.146
 CB
 O
SER C:347 C:357 62.0 0.539 H -64.8 -39.4 62.0 0.539 0.0 HOH
 3.110
 OG
 O
SER D:347 D:357 74.0 0.643 H -67.0 -49.6 74.0 0.643 0.0 HOH
 4.230
 OG
 O
SER E:347 E:357 75.0 0.652 H -67.7 -49.0 75.0 0.652 0.0 HOH
 3.103
 OG
 O
SER F:347 F:357 76.0 0.661 H -54.8 -54.8 76.0 0.661 0.0 HOH
 7.926
 O
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:347 A:357 71.0 0.617 H -63.2 -46.9 71.0 0.617 0.0 HOH
 3.119
 OG
 O
SER B:347 B:357 85.0 0.739 H -75.4 -35.6 85.0 0.739 0.0 HOH
 8.032
 O
 O
SER C:347 C:357 76.0 0.661 H -65.1 -40.6 76.0 0.661 0.0 HOH
 3.460
 N
 O
SER D:347 D:357 71.0 0.617 H -73.8 -25.7 71.0 0.617 0.0 HOH
 6.248
 CB
 O
SER E:347 E:357 81.0 0.704 H -60.0 -49.2 81.0 0.704 0.0 HOH
 4.791
 OG
 O
SER F:347 F:357 84.0 0.73 H -51.4 -45.2 84.0 0.73 0.0 HOH
 3.706
 CA
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:347 A:357 81.0 0.704 H -62.9 -44.8 81.0 0.704 0.0 HOH
 2.845
 OG
 O
SER B:347 B:357 78.0 0.678 H -68.7 -43.1 78.0 0.678 0.0 HOH
 3.716
 N
 O
SER C:347 C:357 82.0 0.713 H -62.1 -43.8 82.0 0.713 0.0 HOH
 3.070
 OG
 O
SER D:347 D:357 82.0 0.713 H -64.0 -49.3 82.0 0.713 0.0 HOH
 5.920
 N
 O
SER E:347 E:357 78.0 0.678 H -63.0 -47.2 78.0 0.678 0.0 HOH
 5.971
 N
 O
SER F:347 F:357 81.0 0.704 H -58.8 -45.9 81.0 0.704 0.0 HOH
 3.934
 OG
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 SER A:347 A:357 71.0 0.617 H -64.2 -41.5 71.0 0.617 0.0 HOH
 2.964
 N
 O
SER B:347 B:357 83.0 0.722 H -56.2 -41.0 83.0 0.722 0.0 HOH
 6.045
 N
 O
SER C:347 C:357 78.0 0.678 H -61.7 -38.8 78.0 0.678 0.0 HOH
 3.437
 N
 O
SER D:347 D:357 79.0 0.687 H -59.8 -51.3 79.0 0.687 0.0 HOH
 3.263
 OG
 O
SER E:347 E:357 87.0 0.757 H -58.0 -48.0 87.0 0.757 0.0 HOH
 6.312
 N
 O
SER F:347 F:357 76.0 0.661 H -59.7 -48.0 76.0 0.661 0.0 HOH
 6.223
 N
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 SER A:347 A:357 78.0 0.678 H -61.9 -51.1 78.0 0.678 0.0 HOH
 8.614
 N
 O
SER B:347 B:357 86.0 0.748 H -44.5 -52.0 86.0 0.748 0.0
SER C:347 C:357 82.0 0.713 H -63.0 -47.2 82.0 0.713 0.0
SER D:347 D:357 82.0 0.713 H -63.0 -62.4 82.0 0.713 0.0
SER E:347 E:357 85.0 0.739 H -54.5 -44.5 85.0 0.739 0.0 HOH
 7.820
 OG
 O
SER F:347 F:357 82.0 0.713 H -61.0 -46.4 82.0 0.713 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 SER A:357 A:357 92.0 0.8 H -63.1 -44.3