Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 11695940 | . | C | A | CCDS5985.1:NM_004462.3:c.1076aCa>aAa_NP_004453.3:p.359T>K | Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3asx | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2011-12-21 | THR | A:329 | A:359 | 0.0 | 0.0 | H | -59.4 | -45.0 | 0.0 | 0.0 | 0.0 |
HOH |
2.722 |
OG1 |
O |
||
| 3lee | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2010-12-08 | THR | A:329 | A:359 | 0.0 | 0.0 | H | -51.5 | -56.0 | 0.0 | 0.0 | 0.0 |
HOH |
8.679 |
O |
O |
||
| THR | B:329 | B:359 | 0.0 | 0.0 | H | -75.3 | -49.4 | NA | NA | NA | |||||||||||||
| THR | C:329 | C:359 | 0.0 | 0.0 | H | -95.0 | -17.4 | NA | NA | NA | |||||||||||||
| THR | D:329 | D:359 | 0.0 | 0.0 | H | -59.8 | -34.7 | NA | NA | NA | |||||||||||||
| THR | E:329 | E:359 | 1.0 | 0.007 | H | -57.7 | -55.7 | NA | NA | NA | |||||||||||||
| THR | F:329 | F:359 | 25.0 | 0.179 | H | -92.0 | -46.2 | NA | NA | NA | |||||||||||||
| 3q2z | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2011-12-21 | THR | A:329 | A:359 | 0.0 | 0.0 | H | -61.2 | -48.5 | 0.0 | 0.0 | 0.0 |
HOH |
2.778 |
OG1 |
O |
||
| 3q30 | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2011-12-21 | THR | A:329 | A:359 | 0.0 | 0.0 | H | -59.2 | -45.3 | 0.0 | 0.0 | 0.0 |
HOH |
2.723 |
OG1 |
O |
||
| 3v66 | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-12-19 | THR | A:329 | A:359 | 0.0 | 0.0 | H | -65.1 | -40.0 | 0.0 | 0.0 | 0.0 |
HOH |
2.748 |
OG1 |
O |
||
| 3vj8 | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-04-11 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -63.3 | -45.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.748 |
OG1 |
O |
||
| 3vj9 | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-04-11 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -66.3 | -45.6 | 0.0 | 0.0 | 0.0 |
HOH |
2.738 |
OG1 |
O |
||
| 3vja | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-04-11 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -65.9 | -41.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.683 |
OG1 |
O |
||
| THR | B:332 | B:359 | 0.0 | 0.0 | H | -61.6 | -46.9 | NA | NA | NA | |||||||||||||
| 3vjb | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-04-11 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -60.7 | -43.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.710 |
OG1 |
O |
||
| THR | B:332 | B:359 | 0.0 | 0.0 | H | -66.7 | -45.5 | 0.0 | 0.0 | 0.0 |
HOH |
2.903 |
OG1 |
O |
|||||||||
| THR | C:332 | C:359 | 0.0 | 0.0 | H | -56.0 | -43.1 | 0.0 | 0.0 | 0.0 |
HOH |
2.997 |
OG1 |
O |
|||||||||
| THR | D:332 | D:359 | 0.0 | 0.0 | H | -68.9 | -43.2 | NA | NA | NA | |||||||||||||
| THR | E:332 | E:359 | 0.0 | 0.0 | H | -59.0 | -48.2 | NA | NA | NA | |||||||||||||
| THR | F:332 | F:359 | 0.0 | 0.0 | H | -67.2 | -45.0 | NA | NA | NA | |||||||||||||
| 3vjc | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2012-04-11 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -66.0 | -43.6 | 0.0 | 0.0 | 0.0 |
HOH |
2.719 |
OG1 |
O |
||
| THR | B:332 | B:359 | 0.0 | 0.0 | H | -68.2 | -41.9 | 0.0 | 0.0 | 0.0 |
HOH |
2.736 |
OG1 |
O |
|||||||||
| THR | C:332 | C:359 | 0.0 | 0.0 | H | -63.4 | -43.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.659 |
OG1 |
O |
|||||||||
| THR | D:332 | D:359 | 0.0 | 0.0 | H | -70.2 | -39.4 | NA | NA | NA | |||||||||||||
| THR | E:332 | E:359 | 0.0 | 0.0 | H | -66.7 | -40.5 | NA | NA | NA | |||||||||||||
| THR | F:332 | F:359 | 0.0 | 0.0 | H | -69.3 | -48.6 | NA | NA | NA | |||||||||||||
| 3wef | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2014-02-12 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -63.0 | -44.8 | 0.0 | 0.0 | 0.0 |
HOH |
2.766 |
OG1 |
O |
||
| THR | B:332 | B:359 | 0.0 | 0.0 | H | -73.8 | -43.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.145 |
C |
O |
|||||||||
| THR | C:332 | C:359 | 0.0 | 0.0 | H | -59.5 | -46.6 | 0.0 | 0.0 | 0.0 |
HOH |
2.840 |
OG1 |
O |
|||||||||
| THR | D:332 | D:359 | 0.0 | 0.0 | H | -70.2 | -41.6 | NA | NA | NA | |||||||||||||
| THR | E:332 | E:359 | 0.0 | 0.0 | H | -62.0 | -37.6 | NA | NA | NA | |||||||||||||
| THR | F:332 | F:359 | 0.0 | 0.0 | H | -68.2 | -45.3 | NA | NA | NA | |||||||||||||
| 3weg | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2014-02-12 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -62.9 | -45.0 | 0.0 | 0.0 | 0.0 |
HOH |
2.731 |
OG1 |
O |
||
| 3weh | 1 | P37268 | 100.0 | 0.0 |
X-RAY |
2014-02-12 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -63.9 | -43.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.690 |
OG1 |
O |
||
| 3wek | 1 | P37268 | 99.71 | 0.0 |
X-RAY |
2014-02-12 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -64.5 | -43.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.647 |
OG1 |
O |
||
| 3wei | 1 | P37268 | 99.71 | 0.0 |
X-RAY |
2014-02-12 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -59.5 | -45.6 | 0.0 | 0.0 | 0.0 |
HOH |
2.688 |
OG1 |
O |
||
| 3wej | 1 | P37268 | 99.71 | 0.0 |
X-RAY |
2014-02-12 | THR | A:332 | A:359 | 0.0 | 0.0 | H | -62.2 | -43.6 | 0.0 | 0.0 | 0.0 |
HOH |
2.824 |
OG1 |
O |
||
| 1ezf | 1 | P37268 | 99.12 | 0.0 |
X-RAY |
2000-10-18 | THR | A:329 | A:359 | 0.0 | 0.0 | H | -55.8 | -44.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.675 |
OG1 |
O |
||
| THR | B:329 | B:359 | 0.0 | 0.0 | H | -58.0 | -43.1 | NA | NA | NA | |||||||||||||
| THR | C:329 | C:359 | 0.0 | 0.0 | H | -63.0 | -44.8 | NA | NA | NA | |||||||||||||
| 3wc9 | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | THR | A:349 | A:359 | 0.0 | 0.0 | H | -54.8 | -38.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.533 |
N |
O |
||
| THR | B:349 | B:359 | 0.0 | 0.0 | H | -52.1 | -45.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.134 |
N |
O |
|||||||||
| THR | C:349 | C:359 | 0.0 | 0.0 | H | -68.3 | -38.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.759 |
OG1 |
O |
|||||||||
| THR | D:349 | D:359 | 0.0 | 0.0 | H | -48.0 | -50.5 | 0.0 | 0.0 | 0.0 |
HOH |
8.353 |
C |
O |
|||||||||
| THR | E:349 | E:359 | 0.0 | 0.0 | H | -59.0 | -48.4 | 0.0 | 0.0 | 0.0 |
HOH |
7.068 |
O |
O |
|||||||||
| THR | F:349 | F:359 | 0.0 | 0.0 | H | -57.5 | -38.8 | 0.0 | 0.0 | 0.0 |
HOH |
9.843 |
C |
O |
|||||||||
| 3wcd | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | THR | A:349 | A:359 | 1.0 | 0.007 | H | -63.6 | -35.6 | 1.0 | 0.007 | 0.0 |
HOH |
2.756 |
OG1 |
O |
||
| THR | B:349 | B:359 | 0.0 | 0.0 | H | -58.6 | -25.6 | 0.0 | 0.0 | 0.0 |
HOH |
8.748 |
N |
O |
|||||||||
| THR | C:349 | C:359 | 0.0 | 0.0 | H | -61.5 | -46.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.866 |
N |
O |
|||||||||
| THR | D:349 | D:359 | 1.0 | 0.007 | H | -70.0 | -44.1 | 1.0 | 0.007 | 0.0 |
HOH |
8.304 |
C |
O |
|||||||||
| THR | E:349 | E:359 | 0.0 | 0.0 | H | -53.9 | -30.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.705 |
C |
O |
|||||||||
| THR | F:349 | F:359 | 0.0 | 0.0 | H | -58.3 | -38.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.239 |
N |
O |
|||||||||
| 3wcf | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | THR | A:349 | A:359 | 0.0 | 0.0 | H | -60.3 | -44.1 | 0.0 | 0.0 | 0.0 |
HOH |
2.748 |
OG1 |
O |
||
| THR | B:349 | B:359 | 0.0 | 0.0 | H | -55.8 | -50.0 | 0.0 | 0.0 | 0.0 |
HOH |
8.479 |
O |
O |
|||||||||
| THR | C:349 | C:359 | 0.0 | 0.0 | H | -62.9 | -43.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.463 |
OG1 |
O |
|||||||||
| THR | D:349 | D:359 | 0.0 | 0.0 | H | -56.2 | -49.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.621 |
OG1 |
O |
|||||||||
| THR | E:349 | E:359 | 1.0 | 0.007 | H | -57.8 | -49.8 | 1.0 | 0.007 | 0.0 |
HOH |
6.879 |
OG1 |
O |
|||||||||
| THR | F:349 | F:359 | 0.0 | 0.0 | H | -63.7 | -48.8 | 0.0 | 0.0 | 0.0 |
HOH |
9.524 |
C |
O |
|||||||||
| 3wch | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | THR | A:349 | A:359 | 0.0 | 0.0 | H | -68.3 | -47.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.715 |
OG1 |
O |
||
| THR | B:349 | B:359 | 0.0 | 0.0 | H | -60.9 | -55.0 | 0.0 | 0.0 | 0.0 |
HOH |
9.408 |
O |
O |
|||||||||
| THR | C:349 | C:359 | 0.0 | 0.0 | H | -70.0 | -45.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.519 |
N |
O |
|||||||||
| THR | D:349 | D:359 | 0.0 | 0.0 | H | -68.1 | -44.4 | 0.0 | 0.0 | 0.0 | |||||||||||||
| THR | E:349 | E:359 | 0.0 | 0.0 | H | -65.5 | -45.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.893 |
N |
O |
|||||||||
| THR | F:349 | F:359 | 0.0 | 0.0 | H | -67.8 | -34.2 | 0.0 | 0.0 | 0.0 |
HOH |
9.057 |
C |
O |
|||||||||
| 3wci | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | THR | A:349 | A:359 | 0.0 | 0.0 | H | -64.7 | -45.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.849 |
OG1 |
O |
||
| THR | B:349 | B:359 | 0.0 | 0.0 | H | -68.1 | -51.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.869 |
N |
O |
|||||||||
| THR | C:349 | C:359 | 0.0 | 0.0 | H | -66.5 | -38.9 | 0.0 | 0.0 | 0.0 |
HOH |
2.821 |
OG1 |
O |
|||||||||
| THR | D:349 | D:359 | 0.0 | 0.0 | H | -65.6 | -45.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.009 |
OG1 |
O |
|||||||||
| THR | E:349 | E:359 | 0.0 | 0.0 | H | -60.2 | -43.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.855 |
OG1 |
O |
|||||||||
| THR | F:349 | F:359 | 0.0 | 0.0 | H | -67.3 | -43.8 | 0.0 | 0.0 | 0.0 |
HOH |
7.296 |
N |
O |
|||||||||
| 3wcj | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | THR | A:349 | A:359 | 0.0 | 0.0 | H | -63.6 | -41.5 | 0.0 | 0.0 | 0.0 |
HOH |
2.779 |
OG1 |
O |
||
| THR | B:349 | B:359 | 0.0 | 0.0 | H | -60.9 | -46.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.696 |
OG1 |
O |
|||||||||
| THR | C:349 | C:359 | 0.0 | 0.0 | H | -67.8 | -42.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.505 |
N |
O |
|||||||||
| THR | D:349 | D:359 | 0.0 | 0.0 | H | -63.0 | -37.3 | 0.0 | 0.0 | 0.0 |
HOH |
7.784 |
C |
O |
|||||||||
| THR | E:349 | E:359 | 0.0 | 0.0 | H | -65.4 | -41.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.478 |
OG1 |
O |
|||||||||
| THR | F:349 | F:359 | 0.0 | 0.0 | H | -62.2 | -44.4 | 0.0 | 0.0 | 0.0 |
HOH |
7.285 |
N |
O |
|||||||||
| 3wcl | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | THR | A:349 | A:359 | 0.0 | 0.0 | H | -66.5 | -40.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.539 |
N |
O |
||
| THR | B:349 | B:359 | 0.0 | 0.0 | H | -62.3 | -47.8 | 0.0 | 0.0 | 0.0 |
HOH |
2.752 |
OG1 |
O |
|||||||||
| THR | C:349 | C:359 | 0.0 | 0.0 | H | -65.8 | -42.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.696 |
N |
O |
|||||||||
| THR | D:349 | D:359 | 0.0 | 0.0 | H | -53.1 | -38.0 | 0.0 | 0.0 | 0.0 |
HOH |
2.561 |
OG1 |
O |
|||||||||
| THR | E:349 | E:359 | 0.0 | 0.0 | H | -63.0 | -44.6 | 0.0 | 0.0 | 0.0 |
HOH |
2.797 |
OG1 |
O |
|||||||||
| THR | F:349 | F:359 | 0.0 | 0.0 | H | -61.8 | -52.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.928 |
OG1 |
O |
|||||||||
| 3wcm | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2014-06-18 | THR | A:349 | A:359 | 0.0 | 0.0 | H | -62.6 | -43.1 | 0.0 | 0.0 | 0.0 |
HOH |
2.849 |
OG1 |
O |
||
| THR | B:349 | B:359 | 0.0 | 0.0 | H | -64.0 | -46.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.718 |
OG1 |
O |
|||||||||
| THR | C:349 | C:359 | 0.0 | 0.0 | H | -64.9 | -42.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.730 |
OG1 |
O |
|||||||||
| THR | D:349 | D:359 | 0.0 | 0.0 | H | -48.5 | -48.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.600 |
N |
O |
|||||||||
| THR | E:349 | E:359 | 0.0 | 0.0 | H | -60.0 | -46.1 | 0.0 | 0.0 | 0.0 |
HOH |
2.790 |
OG1 |
O |
|||||||||
| THR | F:349 | F:359 | 0.0 | 0.0 | H | -56.8 | -45.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.572 |
OG1 |
O |
|||||||||
| 3wsa | 1 | P37268 | 98.82 | 0.0 |
X-RAY |
2015-04-01 | THR | A:349 | A:359 | 0.0 | 0.0 | H | -60.7 | -37.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.654 |
CG2 |
O |
||
| THR | B:349 | B:359 | 0.0 | 0.0 | H | -56.0 | -50.0 | 0.0 | 0.0 | 0.0 | |||||||||||||
| THR | C:349 | C:359 | 0.0 | 0.0 | H | -73.2 | -38.1 | 0.0 | 0.0 | 0.0 |
HOH |
9.845 |
CA |
O |
|||||||||
| THR | D:349 | D:359 | 0.0 | 0.0 | H | -39.8 | -46.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| THR | E:349 | E:359 | 0.0 | 0.0 | H | -49.9 | -40.2 | 0.0 | 0.0 | 0.0 | |||||||||||||
| THR | F:349 | F:359 | 0.0 | 0.0 | H | -55.6 | -36.8 | 0.0 | 0.0 | 0.0 | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p37268-f1 | 1 | P37268 | 100.0 | 0.0 | THR | A:359 | A:359 | 0.0 | 0.0 | H | -61.7 | -47.2 | |