Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 11695967 . C A CCDS5985.1:NM_004462.3:c.1103aCg>aAg_NP_004453.3:p.368T>K Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3asx 1 P37268 100.0 0.0 X-RAY
 2011-12-21 THR A:338 A:368 111.0 0.793 H -85.1 -46.2 111.0 0.793 0.0 HOH
 5.929
 OG1
 O
3lee 1 P37268 100.0 0.0 X-RAY
 2010-12-08 THR A:338 A:368 115.0 0.821 H -108.4 10.3 115.0 0.821 0.0 HOH
 2.779
 OG1
 O
THR B:338 B:368 114.0 0.814 H -115.5 -14.4 NA NA NA
THR C:338 C:368 118.0 0.843 T -106.9 14.9 NA NA NA
THR D:338 D:368 107.0 0.764 -97.9 50.1 NA NA NA
THR E:338 E:368 113.0 0.807 T -133.1 -32.7 NA NA NA
THR F:338 F:368 119.0 0.85 T -99.5 51.5 NA NA NA
3q2z 1 P37268 100.0 0.0 X-RAY
 2011-12-21 THR A:338 A:368 157.0 1.0 -131.3 360.0 157.0 1.0 0.0 HOH
 8.647
 O
 O
3q30 1 P37268 100.0 0.0 X-RAY
 2011-12-21 THR A:338 A:368 148.0 1.0 -102.9 360.0 148.0 1.0 0.0 HOH
 2.400
 O
 O
3v66 1 P37268 100.0 0.0 X-RAY
 2012-12-19 THR A:338 A:368 102.0 0.729 H -101.0 -13.9 102.0 0.729 0.0 HOH
 5.052
 N
 O
3vj8 1 P37268 100.0 0.0 X-RAY
 2012-04-11 THR A:341 A:368 123.0 0.879 H -84.8 -20.4 123.0 0.879 0.0 HOH
 5.483
 C
 O
3vj9 1 P37268 100.0 0.0 X-RAY
 2012-04-11 THR A:341 A:368 118.0 0.843 H -59.2 -34.8 118.0 0.843 0.0 HOH
 3.960
 OG1
 O
3vja 1 P37268 100.0 0.0 X-RAY
 2012-04-11 THR A:341 A:368 116.0 0.829 T -98.4 6.9 116.0 0.829 0.0 HOH
 3.035
 OG1
 O
THR B:341 B:368 119.0 0.85 H -61.7 -25.6 NA NA NA
3vjb 1 P37268 100.0 0.0 X-RAY
 2012-04-11 THR A:341 A:368 104.0 0.743 H -87.0 -42.0 5.0 0.036 0.707 C:P37268:0.707
 HOH
 2.622
 O
 O
THR B:341 B:368 118.0 0.843 H -83.5 -30.2 13.0 0.093 0.75 A:P37268:0.75
 HOH
 3.152
 O
 O
THR C:341 C:368 99.0 0.707 H -67.0 -42.9 55.0 0.393 0.314 B:P37268:0.314
 HOH
 2.575
 O
 O
THR D:341 D:368 116.0 0.829 H -86.2 -28.1 NA NA NA
THR E:341 E:368 113.0 0.807 H -102.3 -24.0 NA NA NA
THR F:341 F:368 110.0 0.786 H -100.6 -24.7 NA NA NA
3vjc 1 P37268 100.0 0.0 X-RAY
 2012-04-11 THR A:341 A:368 108.0 0.771 H -100.7 -14.8 27.0 0.193 0.578 C:P37268:0.579
 HOH
 3.075
 O
 O
THR B:341 B:368 119.0 0.85 H -87.2 -29.8 12.0 0.086 0.764 A:P37268:0.764
 HOH
 2.918
 O
 O
THR C:341 C:368 151.0 1.0 -88.3 360.0 108.0 0.771 0.229 B:P37268:0.307
 HOH
 2.920
 OG1
 O
THR D:341 D:368 116.0 0.829 H -101.4 -15.7 NA NA NA
THR E:341 E:368 118.0 0.843 T -88.2 -15.6 NA NA NA
THR F:341 F:368 115.0 0.821 T -124.0 52.9 NA NA NA
3wef 1 P37268 100.0 0.0 X-RAY
 2014-02-12 THR A:341 A:368 114.0 0.814 H -90.6 -35.4 6.0 0.043 0.771 C:P37268:0.771
 HOH
 3.944
 OG1
 O
THR B:341 B:368 116.0 0.829 H -95.8 -28.7 10.0 0.071 0.758 A:P37268:0.757
 HOH
 3.291
 O
 O
THR C:341 C:368 161.0 1.0 -151.1 360.0 102.0 0.729 0.271 B:P37268:0.421
 HOH
 4.556
 O
 O
THR D:341 D:368 114.0 0.814 H -105.3 -25.9 NA NA NA
THR E:341 E:368 92.0 0.657 -53.7 -70.2 NA NA NA
THR F:341 F:368 108.0 0.771 H -106.8 -12.2 NA NA NA
3weg 1 P37268 100.0 0.0 X-RAY
 2014-02-12 THR A:341 A:368 116.0 0.829 H -106.6 0.9 116.0 0.829 0.0 HOH
 3.141
 OG1
 O
3weh 1 P37268 100.0 0.0 X-RAY
 2014-02-12 THR A:341 A:368 116.0 0.829 H -102.2 -9.3 116.0 0.829 0.0 HOH
 4.722
 N
 O
3wek 1 P37268 99.71 0.0 X-RAY
 2014-02-12 THR A:341 A:368 121.0 0.864 T -110.0 14.3 121.0 0.864 0.0 HOH
 4.326
 N
 O
3wei 1 P37268 99.71 0.0 X-RAY
 2014-02-12 THR A:341 A:368 119.0 0.85 T -107.5 10.4 119.0 0.85 0.0 HOH
 2.836
 O
 O
3wej 1 P37268 99.71 0.0 X-RAY
 2014-02-12 THR A:341 A:368 119.0 0.85 H -92.5 -20.1 119.0 0.85 0.0 HOH
 4.967
 C
 O
1ezf 1 P37268 99.12 0.0 X-RAY
 2000-10-18 THR A:338 A:368 120.0 0.857 T -107.1 21.7 120.0 0.857 0.0 HOH
 4.327
 CG2
 O
THR B:338 B:368 122.0 0.871 H -77.5 -7.5 NA NA NA
THR C:338 C:368 110.0 0.786 H -94.6 -9.2 NA NA NA
3wc9 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:358 A:368 152.0 1.0 -103.1 360.0 52.0 0.371 0.629 B:P37268:0.714
 HOH
 2.849
 O
 O
THR B:358 B:368 120.0 0.857 T -105.4 31.0 23.0 0.164 0.693 C:P37268:0.693
 HOH
 5.363
 OG1
 O
THR C:358 C:368 114.0 0.814 T -93.3 19.7 17.0 0.121 0.693 A:P37268:0.693
 HOH
 6.670
 OG1
 O
THR D:358 D:368 112.0 0.8 H -72.1 -40.4 16.0 0.114 0.686 E:P37268:0.686
 HOH
 4.553
 O
 O
THR E:358 E:368 116.0 0.829 H -104.2 -29.3 11.0 0.079 0.75 F:P37268:0.75
 HOH
 6.443
 O
 O
THR F:358 F:368 113.0 0.807 H -98.9 -8.4 33.0 0.236 0.571 D:P37268:0.571
 HOH
 3.545
 O
 O
3wcd 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:358 A:368 104.0 0.743 H -85.4 -60.8 4.0 0.029 0.714 B:P37268:0.714
 HOH
 3.513
 OG1
 O
THR B:358 B:368 117.0 0.836 T -123.8 43.9 32.0 0.229 0.607 C:P37268:0.607
 HOH
 3.111
 O
 O
THR C:358 C:368 110.0 0.786 H -98.4 -0.7 12.0 0.086 0.7 A:P37268:0.7
 HOH
 3.741
 O
 O
THR D:358 D:368 115.0 0.821 H -78.3 -37.0 11.0 0.079 0.742 E:P37268:0.743
 HOH
 5.080
 C
 O
THR E:358 E:368 119.0 0.85 H -72.6 -30.9 6.0 0.043 0.807 F:P37268:0.807
 HOH
 3.673
 O
 O
THR F:358 F:368 113.0 0.807 -120.7 74.9 35.0 0.25 0.557 D:P37268:0.557
 HOH
 4.644
 O
 O
3wcf 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:358 A:368 112.0 0.8 H -74.0 -36.2 12.0 0.086 0.714 B:P37268:0.714
 HOH
 2.638
 O
 O
THR B:358 B:368 117.0 0.836 H -74.3 -12.3 20.0 0.143 0.693 C:P37268:0.693
 HOH
 4.580
 OG1
 O
THR C:358 C:368 117.0 0.836 H -74.8 -22.0 13.0 0.093 0.743 A:P37268:0.743
 HOH
 3.659
 O
 O
THR D:358 D:368 115.0 0.821 H -76.3 -31.9 14.0 0.1 0.721 E:P37268:0.721
 HOH
 5.795
 C
 O
THR E:358 E:368 112.0 0.8 H -72.1 -34.8 7.0 0.05 0.75 F:P37268:0.75
 HOH
 3.847
 OG1
 O
THR F:358 F:368 117.0 0.836 H -73.8 -33.2 12.0 0.086 0.75 D:P37268:0.75
 HOH
 4.473
 O
 O
3wch 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:358 A:368 113.0 0.807 H -77.2 -34.0 9.0 0.064 0.743 B:P37268:0.743
 HOH
 2.776
 O
 O
THR B:358 B:368 117.0 0.836 T -95.0 7.3 18.0 0.129 0.707 C:P37268:0.707
 HOH
 3.995
 OG1
 O
THR C:358 C:368 119.0 0.85 H -54.9 -24.1 15.0 0.107 0.743 A:P37268:0.743
 HOH
 3.423
 O
 O
THR D:358 D:368 115.0 0.821 H -81.3 -14.0 21.0 0.15 0.671 E:P37268:0.671
 HOH
 3.049
 O
 O
THR E:358 E:368 114.0 0.814 H -78.8 -23.2 11.0 0.079 0.735 F:P37268:0.736
 HOH
 2.877
 O
 O
THR F:358 F:368 113.0 0.807 H -89.5 -11.2 17.0 0.121 0.686 D:P37268:0.686
 HOH
 4.352
 O
 O
3wci 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:358 A:368 112.0 0.8 H -76.6 -47.7 4.0 0.029 0.771 B:P37268:0.771
 HOH
 2.686
 O
 O
THR B:358 B:368 115.0 0.821 T -99.5 11.9 25.0 0.179 0.642 C:P37268:0.643
 HOH
 3.796
 O
 O
THR C:358 C:368 121.0 0.864 H -77.8 -26.1 9.0 0.064 0.8 A:P37268:0.8
 HOH
 2.845
 O
 O
THR D:358 D:368 110.0 0.786 H -91.6 -17.9 18.0 0.129 0.657 E:P37268:0.657
 HOH
 2.992
 O
 O
THR E:358 E:368 116.0 0.829 H -88.0 -16.3 5.0 0.036 0.793 F:P37268:0.793
 HOH
 2.685
 O
 O
THR F:358 F:368 117.0 0.836 H -65.7 -47.3 4.0 0.029 0.807 D:P37268:0.807
 HOH
 4.978
 O
 O
3wcj 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:358 A:368 101.0 0.721 H -81.0 -42.1 5.0 0.036 0.685 B:P37268:0.686
 HOH
 2.612
 O
 O
THR B:358 B:368 110.0 0.786 H -89.5 -13.7 19.0 0.136 0.65 C:P37268:0.65
 HOH
 3.657
 O
 O
THR C:358 C:368 104.0 0.743 H -88.4 -1.8 12.0 0.086 0.657 A:P37268:0.657
 HOH
 3.276
 O
 O
THR D:358 D:368 99.0 0.707 H -85.8 -38.6 14.0 0.1 0.607 E:P37268:0.607
 HOH
 5.834
 OG1
 O
THR E:358 E:368 101.0 0.721 H -86.1 -27.1 8.0 0.057 0.664 F:P37268:0.664
 HOH
 5.595
 C
 O
THR F:358 F:368 112.0 0.8 T -108.5 44.8 33.0 0.236 0.564 D:P37268:0.564
 HOH
 4.017
 O
 O
3wcl 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:358 A:368 110.0 0.786 H -81.0 -41.6 11.0 0.079 0.707 B:P37268:0.707
 HOH
 3.058
 O
 O
THR B:358 B:368 113.0 0.807 T -83.7 16.6 17.0 0.121 0.686 C:P37268:0.686
 HOH
 2.760
 O
 O
THR C:358 C:368 118.0 0.843 H -79.6 -19.2 18.0 0.129 0.714 A:P37268:0.714
 HOH
 3.150
 O
 O
THR D:358 D:368 95.0 0.679 T -99.0 9.2 13.0 0.093 0.586 E:P37268:0.586
 HOH
 3.671
 CG2
 O
THR E:358 E:368 109.0 0.779 H -77.9 -19.8 2.0 0.014 0.765 F:P37268:0.764
 HOH
 3.253
 O
 O
THR F:358 F:368 118.0 0.843 H -81.7 -29.0 7.0 0.05 0.793 D:P37268:0.793
 HOH
 2.916
 O
 O
3wcm 1 P37268 98.82 0.0 X-RAY
 2014-06-18 THR A:358 A:368 106.0 0.757 H -71.3 -37.6 6.0 0.043 0.714 B:P37268:0.714
 HOH
 2.626
 O
 O
THR B:358 B:368 113.0 0.807 T -77.7 46.6 19.0 0.136 0.671 C:P37268:0.671
 HOH
 4.800
 CG2
 O
THR C:358 C:368 115.0 0.821 H -73.5 -33.6 5.0 0.036 0.785 A:P37268:0.786
 HOH
 3.056
 O
 O
THR D:358 D:368 106.0 0.757 H -83.7 -6.7 28.0 0.2 0.557 E:P37268:0.557
 HOH
 3.379
 O
 O
THR E:358 E:368 93.0 0.664 H -83.6 -31.2 0.0 0.0 0.664 F:P37268:0.664
 HOH
 5.336
 C
 O
THR F:358 F:368 118.0 0.843 H -94.0 1.0 25.0 0.179 0.664 D:P37268:0.664
 HOH
 3.398
 O
 O
3wsa 1 P37268 98.82 0.0 X-RAY
 2015-04-01 THR A:358 A:368 100.0 0.714 H -67.7 -82.6 1.0 0.007 0.707 B:P37268:0.707
 HOH
 7.009
 O
 O
THR B:358 B:368 105.0 0.75 T -117.3 28.0 8.0 0.057 0.693 C:P37268:0.693
 HOH
 8.430
 O
 O
THR C:358 C:368 117.0 0.836 H -59.1 -48.5 12.0 0.086 0.75 A:P37268:0.75
 HOH
 6.781
 O
 O
THR D:358 D:368 98.0 0.7 H -91.0 -35.4 22.0 0.157 0.543 E:P37268:0.543
 HOH
 3.405
 CG2
 O
THR E:358 E:368 110.0 0.786 H -63.9 -51.5 1.0 0.007 0.779 F:P37268:0.779
 HOH
 9.413
 O
 O
THR F:358 F:368 117.0 0.836 H -67.9 -30.5 23.0 0.164 0.672 D:P37268:0.671
 HOH
 4.916
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37268-f1 1 P37268 100.0 0.0 THR A:368 A:368 98.0 0.7 H -72.2 -42.0