Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 38283760 | . | G | A | CCDS6107.2:NM_023110.2:c.625Cgt>Tgt_NP_075598.2:p.209R>C | Homo sapiens fibroblast growth factor receptor 1 (FGFR1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1evt | 2 | P11362 | 100.0 | 1e-163 |
X-RAY |
2000-05-31 | ARG | C:69 | C:209 | 37.0 | NA | E | -84.6 | 97.6 | 37.0 | NA | NA | ||||||
| ARG | D:69 | D:209 | 39.0 | NA | E | -84.3 | 96.8 | 39.0 | NA | NA | |||||||||||||
| 1cvs | 2 | P11362 | 99.56 | 5e-163 |
X-RAY |
2000-01-28 | ARG | C:69 | C:209 | 38.0 | NA | E | -82.5 | 104.7 | 38.0 | NA | NA | ||||||
| ARG | D:69 | D:209 | 40.0 | NA | E | -81.1 | 103.8 | 40.0 | NA | NA | |||||||||||||
| 1fq9 | 2 | P11362 | 99.56 | 5e-163 |
X-RAY |
2000-09-27 | ARG | C:69 | C:209 | 130.0 | 0.578 | E | -105.9 | 84.8 | 130.0 | 0.578 | 0.0 |
UAP IDS SGN IDS SGN UAP |
9.477 8.686 3.126 3.140 3.941 3.758 |
CB NH2 NH2 NH2 NH2 CG |
O6A O6B O6S O2 N2 O6B |
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| ARG | D:69 | D:209 | 131.0 | 0.582 | E | -106.2 | 88.8 | 131.0 | 0.582 | 0.0 |
SGN IDS SGN UAP UAP |
6.262 4.702 6.186 5.774 9.168 |
NH1 NH1 NH1 CB CG |
O5S O1S O1S O6B O6A |
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| 3ojv | 2 | P11362 | 99.55 | 2e-162 |
X-RAY |
2011-12-28 | ARG | C:70 | C:209 | 39.0 | NA | E | -120.3 | 89.9 | 39.0 | NA | NA |
HOH |
9.129 |
N |
O |
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| ARG | D:70 | D:209 | 144.0 | 0.64 | E | -121.1 | 90.6 | NA | NA | NA | |||||||||||||
| 5w21 | 3 | P11362 | 99.55 | 2e-162 |
X-RAY |
2018-01-24 | ARG | C:70 | C:209 | 33.0 | NA | E | -100.1 | 106.4 | 33.0 | NA | NA | ||||||
| 5w59 | 2 | P11362 | 99.11 | 4e-161 |
X-RAY |
2017-08-16 | ARG | B:70 | B:209 | 42.0 | NA | E | -90.3 | 106.7 | 42.0 | NA | NA |
HOH |
7.308 |
N |
O |
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| 4wv1 | 1 | P21802 | 80.81 | 7e-53 |
X-RAY |
2015-09-16 | ARG | A:58 | F:207 | 134.0 | 0.596 | E | -138.1 | 87.9 | 60.0 | 0.267 | 0.329 |
F:None:0.329 |
HOH |
2.615 |
NH1 |
O |
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| ARG | B:58 | C:207 | 134.0 | 0.596 | E | -138.3 | 89.3 | NA | NA | NA | |||||||||||||
| 3dar | 1 | P21802 | 80.41 | 1e-51 |
X-RAY |
2008-06-10 | ARG | A:66 | A:210 | 54.0 | NA | E | -109.5 | 101.7 | 54.0 | NA | NA |
HOH |
3.845 |
C |
O |
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| ARG | B:66 | B:210 | 36.0 | NA | E | -110.1 | 103.3 | NA | NA | NA | |||||||||||||
| 3caf | 1 | P21802 | 80.41 | 2e-51 |
X-RAY |
2009-01-27 | ARG | A:61 | A:210 | 107.0 | 0.476 | E | -108.8 | 95.1 | 107.0 | 0.476 | 0.0 |
HOH |
8.018 |
C |
O |
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| 3cu1 | 1 | P21802 | 80.41 | 2e-51 |
X-RAY |
2009-04-21 | ARG | A:61 | A:210 | 91.0 | 0.404 | E | -122.0 | 94.8 | 53.0 | 0.236 | 0.168 |
D:P05230:0.169 |
GU4 YYJ HOH |
2.761 4.807 4.088 |
NH2 NH1 NE |
O23 O1 O |
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| ARG | C:61 | C:210 | 112.0 | 0.498 | E | -108.1 | 97.9 | 105.0 | 0.467 | 0.031 |
B:P05230:0.031 |
GU4 YYJ HOH |
2.953 4.538 3.595 |
NH1 NH1 NE |
O12 O2S1 O |
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| 3euu | 1 | P21802 | 80.41 | 2e-51 |
X-RAY |
2009-08-25 | ARG | A:61 | A:210 | 111.0 | 0.493 | E | -106.7 | 95.8 | 111.0 | 0.493 | 0.0 |
HOH |
6.928 |
O |
O |
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| ARG | B:61 | B:210 | 110.0 | 0.489 | E | -108.8 | 93.3 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p11362-f1 | 1 | P11362 | 100.0 | 0.0 | ARG | A:209 | A:209 | 152.0 | 0.676 | E | -102.3 | 95.4 | |