Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 38285566 | . | A | C | CCDS6107.2:NM_023110.2:c.494tTg>tGg_NP_075598.2:p.165L>W | Homo sapiens fibroblast growth factor receptor 1 (FGFR1), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1evt | 2 | P11362 | 100.0 | 1e-163 |
X-RAY |
2000-05-31 | LEU | C:25 | C:165 | 100.0 | 0.588 | E | -89.7 | 126.4 | 27.0 | 0.159 | 0.429 |
A:P05230:0.429 |
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LEU | D:25 | D:165 | 100.0 | 0.588 | E | -91.5 | 126.7 | 28.0 | 0.165 | 0.423 |
B:P05230:0.424 |
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1cvs | 2 | P11362 | 99.56 | 5e-163 |
X-RAY |
2000-01-28 | LEU | C:25 | C:165 | 83.0 | 0.488 | E | -97.7 | 124.1 | 21.0 | 0.124 | 0.364 |
A:P09038:0.365 |
SO4 |
8.779 |
O |
O4 |
|
LEU | D:25 | D:165 | 87.0 | 0.512 | E | -99.2 | 121.8 | 21.0 | 0.124 | 0.388 |
B:P09038:0.388 |
SO4 |
8.484 |
O |
O4 |
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1fq9 | 2 | P11362 | 99.56 | 5e-163 |
X-RAY |
2000-09-27 | LEU | C:25 | C:165 | 90.0 | 0.529 | E | -107.5 | 118.7 | 21.0 | 0.124 | 0.405 |
A:P09038:0.406 |
SGN |
6.733 |
O |
O5S |
|
LEU | D:25 | D:165 | 87.0 | 0.512 | E | -109.4 | 118.6 | 19.0 | 0.112 | 0.4 |
B:P09038:0.4 |
SGN |
6.941 |
O |
O5S |
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3ojv | 2 | P11362 | 99.55 | 2e-162 |
X-RAY |
2011-12-28 | LEU | C:26 | C:165 | 107.0 | 0.629 | E | -93.8 | 120.2 | 30.0 | 0.176 | 0.453 |
A:P05230:0.453 |
UAP |
9.928 |
O |
O6A |
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LEU | D:26 | D:165 | 107.0 | 0.629 | E | -94.6 | 120.9 | NA | NA | NA | |||||||||||||
5w21 | 3 | P11362 | 99.55 | 2e-162 |
X-RAY |
2018-01-24 | LEU | C:26 | C:165 | 85.0 | 0.5 | E | -103.0 | 131.0 | 3.0 | 0.018 | 0.482 |
B:Q9GZV9:0.482 |
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5w59 | 2 | P11362 | 99.11 | 4e-161 |
X-RAY |
2017-08-16 | LEU | B:26 | B:165 | 97.0 | 0.571 | E | -97.3 | 122.1 | 18.0 | 0.106 | 0.465 |
A:P31371:0.465 |
HOH |
6.988 |
O |
O |
|
4wv1 | 1 | P21802 | 80.81 | 7e-53 |
X-RAY |
2015-09-16 | LEU | A:14 | F:163 | 129.0 | 0.759 | E | -83.4 | 126.7 | 117.0 | 0.688 | 0.071 |
D:None:0.071 |
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LEU | B:14 | C:163 | 129.0 | 0.759 | E | -83.2 | 126.3 | NA | NA | NA | |||||||||||||
3dar | 1 | P21802 | 80.41 | 1e-51 |
X-RAY |
2008-06-10 | LEU | A:22 | A:166 | 122.0 | 0.718 | E | -107.3 | 123.7 | 122.0 | 0.718 | 0.0 |
HOH |
3.372 |
N |
O |
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LEU | B:22 | B:166 | 133.0 | 0.782 | E | -107.3 | 124.9 | NA | NA | NA | |||||||||||||
3caf | 1 | P21802 | 80.41 | 2e-51 |
X-RAY |
2009-01-27 | LEU | A:17 | A:166 | 141.0 | 0.829 | E | -106.1 | 129.1 | 141.0 | 0.829 | 0.0 |
HOH |
3.088 |
CB |
O |
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3cu1 | 1 | P21802 | 80.41 | 2e-51 |
X-RAY |
2009-04-21 | LEU | A:17 | A:166 | 98.0 | 0.576 | E | -99.1 | 119.5 | 29.0 | 0.171 | 0.405 |
B:P05230:0.406 |
HOH |
2.937 |
N |
O |
|
LEU | C:17 | C:166 | 103.0 | 0.606 | E | -92.7 | 113.4 | 25.0 | 0.147 | 0.459 |
D:P05230:0.459 |
HOH |
3.146 |
N |
O |
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3euu | 1 | P21802 | 80.41 | 2e-51 |
X-RAY |
2009-08-25 | LEU | A:17 | A:166 | 133.0 | 0.782 | E | -105.1 | 119.3 | 133.0 | 0.782 | 0.0 |
HOH |
3.188 |
CB |
O |
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LEU | B:17 | B:166 | 136.0 | 0.8 | E | -97.6 | 127.6 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p11362-f1 | 1 | P11362 | 100.0 | 0.0 | LEU | A:165 | A:165 | 86.0 | 0.506 | E | -99.2 | 120.8 |