Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 54960654 | . | T | A | CCDS6157.1:NM_006330.3:c.664Att>Ttt_NP_006321.1:p.222I>F | Homo sapiens lysophospholipase I (LYPLA1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5sym | 1 | O75608 | 100.0 | 9e-174 |
X-RAY |
2016-10-26 | ILE | A:222 | A:222 | 1.0 | 0.006 | H | -60.2 | -45.8 | 1.0 | 0.006 | 0.0 |
HOH |
3.039 |
HG21 |
O |
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| ILE | B:222 | B:222 | 1.0 | 0.006 | H | -63.8 | -46.2 | NA | NA | NA | |||||||||||||
| 6qgs | 1 | O75608 | 100.0 | 9e-174 |
X-RAY |
2020-02-05 | ILE | A:225 | B:222 | 1.0 | 0.006 | H | -69.1 | -41.9 | 1.0 | 0.006 | 0.0 |
HOH |
4.098 |
CG2 |
O |
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| ILE | B:225 | D:222 | 1.0 | 0.006 | H | -68.0 | -47.2 | NA | NA | NA | |||||||||||||
| ILE | C:225 | A:222 | 1.0 | 0.006 | H | -66.8 | -38.6 | NA | NA | NA | |||||||||||||
| ILE | D:225 | C:222 | 1.0 | 0.006 | H | -63.7 | -39.5 | NA | NA | NA | |||||||||||||
| ILE | E:225 | E:222 | 2.0 | 0.011 | H | -72.0 | -38.6 | NA | NA | NA | |||||||||||||
| ILE | F:225 | F:222 | 0.0 | 0.0 | H | -71.7 | -39.8 | NA | NA | NA | |||||||||||||
| 6qgo | 1 | O75608 | 99.57 | 3e-173 |
X-RAY |
2020-02-05 | ILE | A:225 | B:222 | 0.0 | 0.0 | H | -70.7 | -44.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.858 |
CG2 |
O |
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| ILE | B:225 | C:222 | 1.0 | 0.006 | H | -70.1 | -43.6 | NA | NA | NA | |||||||||||||
| 6qgq | 2 | O75608 | 99.57 | 1e-172 |
X-RAY |
2020-02-05 | ILE | B:225 | B:222 | 1.0 | 0.006 | H | -64.5 | -46.3 | NA | NA | NA | ||||||
| 6qgn | 1 | O75608 | 99.57 | 1e-172 |
X-RAY |
2020-02-05 | ILE | A:225 | A:222 | 1.0 | 0.006 | H | -62.5 | -43.8 | 1.0 | 0.006 | 0.0 |
HOH |
3.589 |
CG2 |
O |
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| ILE | B:225 | B:222 | 0.0 | 0.0 | H | -64.4 | -37.8 | NA | NA | NA | |||||||||||||
| ILE | C:225 | C:222 | 0.0 | 0.0 | H | -61.3 | -52.1 | NA | NA | NA | |||||||||||||
| ILE | D:225 | D:222 | 0.0 | 0.0 | H | -61.8 | -45.8 | NA | NA | NA | |||||||||||||
| 6qgq | 1 | O75608 | 99.57 | 1e-172 |
X-RAY |
2020-02-05 | ILE | A:225 | A:222 | 1.0 | 0.006 | H | -68.3 | -45.8 | 1.0 | 0.006 | 0.0 |
HOH |
9.020 |
N |
O |
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| ILE | C:225 | C:222 | 1.0 | 0.006 | H | -65.2 | -51.8 | NA | NA | NA | |||||||||||||
| ILE | D:225 | D:222 | 1.0 | 0.006 | H | -72.3 | -32.1 | NA | NA | NA | |||||||||||||
| 1fj2 | 1 | O75608 | 100.0 | 9e-169 |
X-RAY |
2000-11-29 | ILE | A:224 | A:217 | 1.0 | 0.006 | H | -59.9 | -46.9 | 1.0 | 0.006 | 0.0 |
BR BR HOH |
7.428 9.019 3.605 |
N N CG2 |
BR BR O |
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| ILE | B:224 | B:217 | 1.0 | 0.006 | H | -61.6 | -46.9 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o75608-f1 | 1 | O75608 | 100.0 | 4e-174 | ILE | A:222 | A:222 | 1.0 | 0.006 | H | -59.7 | -50.9 | |