Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 54963657 | . | G | A | CCDS6157.1:NM_006330.3:c.554aCg>aTg_NP_006321.1:p.185T>M | Homo sapiens lysophospholipase I (LYPLA1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5sym | 1 | O75608 | 100.0 | 9e-174 |
X-RAY |
2016-10-26 | THR | A:185 | A:185 | 11.0 | 0.079 | H | -64.5 | -48.8 | 11.0 | 0.079 | 0.0 |
71Q HOH |
2.968 4.278 |
HG1 HA |
C14 O |
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| THR | B:185 | B:185 | 9.0 | 0.064 | H | -62.1 | -48.3 | NA | NA | NA | |||||||||||||
| 6qgs | 1 | O75608 | 100.0 | 9e-174 |
X-RAY |
2020-02-05 | THR | A:188 | B:185 | 1.0 | 0.007 | H | -70.1 | -50.6 | 1.0 | 0.007 | 0.0 |
HOH |
6.229 |
CB |
O |
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| THR | B:188 | D:185 | 14.0 | 0.1 | H | -70.3 | -42.1 | NA | NA | NA | |||||||||||||
| THR | C:188 | A:185 | 9.0 | 0.064 | H | -70.7 | -51.5 | NA | NA | NA | |||||||||||||
| THR | D:188 | C:185 | 2.0 | 0.014 | H | -64.4 | -49.2 | NA | NA | NA | |||||||||||||
| THR | E:188 | E:185 | 7.0 | 0.05 | H | -73.3 | -27.9 | NA | NA | NA | |||||||||||||
| THR | F:188 | F:185 | 10.0 | 0.071 | H | -72.3 | -44.1 | NA | NA | NA | |||||||||||||
| 6qgo | 1 | O75608 | 99.57 | 3e-173 |
X-RAY |
2020-02-05 | THR | A:188 | B:185 | 9.0 | 0.064 | H | -59.5 | -41.1 | 9.0 | 0.064 | 0.0 |
PLM |
3.172 |
OG1 |
CG |
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| THR | B:188 | C:185 | 7.0 | 0.05 | H | -65.5 | -49.9 | NA | NA | NA | |||||||||||||
| 6qgq | 2 | O75608 | 99.57 | 1e-172 |
X-RAY |
2020-02-05 | THR | B:188 | B:185 | 10.0 | 0.071 | H | -64.9 | -49.4 | NA | NA | NA | ||||||
| 6qgn | 1 | O75608 | 99.57 | 1e-172 |
X-RAY |
2020-02-05 | THR | A:188 | A:185 | 12.0 | 0.086 | H | -70.2 | -49.7 | 12.0 | 0.086 | 0.0 |
J1W HOH |
2.534 4.709 |
OG1 N |
H021 O |
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| THR | B:188 | B:185 | 10.0 | 0.071 | H | -66.3 | -44.4 | NA | NA | NA | |||||||||||||
| THR | C:188 | C:185 | 11.0 | 0.079 | H | -57.6 | -41.0 | NA | NA | NA | |||||||||||||
| THR | D:188 | D:185 | 12.0 | 0.086 | H | -63.1 | -41.3 | NA | NA | NA | |||||||||||||
| 6qgq | 1 | O75608 | 99.57 | 1e-172 |
X-RAY |
2020-02-05 | THR | A:188 | A:185 | 0.0 | 0.0 | H | -73.3 | -39.4 | 0.0 | 0.0 | 0.0 |
HOH |
7.171 |
CB |
O |
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| THR | C:188 | C:185 | 2.0 | 0.014 | H | -73.5 | -49.0 | NA | NA | NA | |||||||||||||
| THR | D:188 | D:185 | 0.0 | 0.0 | H | -65.7 | -44.8 | NA | NA | NA | |||||||||||||
| 1fj2 | 1 | O75608 | 100.0 | 9e-169 |
X-RAY |
2000-11-29 | THR | A:187 | A:180 | 0.0 | 0.0 | H | -65.0 | -47.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.097 |
N |
O |
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| THR | B:187 | B:180 | 0.0 | 0.0 | H | -67.1 | -45.4 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o75608-f1 | 1 | O75608 | 100.0 | 4e-174 | THR | A:185 | A:185 | 2.0 | 0.014 | H | -70.3 | -52.5 | |