Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86240815 | . | C | A | CCDS6237.1:NM_001128829.2:c.760Ggc>Tgc_NP_001122301.1:p.254G>C | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | GLY | A:254 | A:253 | 77.0 | 1.0 | T | 95.2 | -9.3 | 77.0 | 1.0 | 0.0 |
HOH |
2.804 |
N |
O |
||
| GLY | B:254 | B:253 | 78.0 | 1.0 | T | 85.4 | -16.3 | NA | NA | NA | |||||||||||||
| 6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | GLY | A:254 | A:253 | 74.0 | 0.987 | T | 81.0 | 2.0 | 74.0 | 0.987 | 0.0 |
HOH |
4.740 |
N |
O |
||
| GLY | B:254 | B:253 | 77.0 | 1.0 | T | 88.1 | -8.6 | NA | NA | NA | |||||||||||||
| 6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | GLY | A:254 | A:253 | 77.0 | 1.0 | T | 82.2 | -2.1 | 77.0 | 1.0 | 0.0 |
HOH |
4.804 |
N |
O |
||
| GLY | B:254 | B:253 | 76.0 | 1.0 | T | 90.5 | -7.5 | NA | NA | NA | |||||||||||||
| 6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | GLY | A:254 | A:253 | 77.0 | 1.0 | T | 75.4 | 6.9 | 77.0 | 1.0 | 0.0 |
HOH |
2.817 |
N |
O |
||
| GLY | B:254 | B:253 | 77.0 | 1.0 | T | 82.1 | 0.8 | NA | NA | NA | |||||||||||||
| 6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | GLY | A:254 | A:253 | 83.0 | 1.0 | T | 72.4 | 3.4 | 83.0 | 1.0 | 0.0 |
HOH |
2.647 |
O |
O |
||
| GLY | B:254 | B:253 | 78.0 | 1.0 | T | 86.7 | -1.3 | NA | NA | NA | |||||||||||||
| 6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | GLY | A:254 | A:253 | 83.0 | 1.0 | T | 92.7 | -14.9 | 83.0 | 1.0 | 0.0 |
HOH |
4.998 |
O |
O |
||
| GLY | B:254 | B:253 | 76.0 | 1.0 | T | 90.1 | -11.0 | NA | NA | NA | |||||||||||||
| 6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | GLY | A:254 | A:253 | 73.0 | 0.973 | T | 79.1 | 8.6 | 73.0 | 0.973 | 0.0 |
HOH |
4.823 |
N |
O |
||
| GLY | B:254 | B:253 | 78.0 | 1.0 | T | 89.0 | 3.5 | NA | NA | NA | |||||||||||||
| 6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | GLY | A:254 | A:254 | 75.0 | 1.0 | T | 78.6 | -5.6 | 75.0 | 1.0 | 0.0 |
HOH |
7.495 |
N |
O |
||
| GLY | B:254 | B:254 | 75.0 | 1.0 | T | 94.6 | -10.7 | NA | NA | NA | |||||||||||||
| 6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:254 | A:253 | 76.0 | 1.0 | T | 80.3 | -4.6 | 76.0 | 1.0 | 0.0 |
HOH |
2.853 |
N |
O |
||
| GLY | B:254 | B:253 | 77.0 | 1.0 | T | 88.5 | -1.8 | NA | NA | NA | |||||||||||||
| 6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:254 | A:253 | 76.0 | 1.0 | T | 79.7 | 2.6 | 76.0 | 1.0 | 0.0 |
HOH |
4.751 |
N |
O |
||
| GLY | B:254 | B:253 | 78.0 | 1.0 | T | 88.9 | -8.7 | NA | NA | NA | |||||||||||||
| 6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | GLY | A:254 | A:253 | 72.0 | 0.96 | T | 85.4 | 16.2 | 72.0 | 0.96 | 0.0 |
HOH |
5.469 |
O |
O |
||
| GLY | B:254 | B:253 | 79.0 | 1.0 | S | 82.7 | 2.0 | NA | NA | NA | |||||||||||||
| 6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLY | A:254 | A:253 | 76.0 | 1.0 | T | 85.9 | -4.8 | 76.0 | 1.0 | 0.0 |
HOH |
2.904 |
N |
O |
||
| GLY | B:254 | B:253 | 77.0 | 1.0 | T | 83.9 | -4.0 | NA | NA | NA | |||||||||||||
| 6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLY | A:254 | A:253 | 74.0 | 0.987 | T | 86.5 | -0.2 | 74.0 | 0.987 | 0.0 |
HOH |
3.003 |
N |
O |
||
| GLY | B:254 | B:253 | 75.0 | 1.0 | T | 80.8 | -3.0 | NA | NA | NA | |||||||||||||
| 6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLY | A:254 | A:253 | 76.0 | 1.0 | T | 85.7 | -2.9 | 76.0 | 1.0 | 0.0 |
HOH |
3.048 |
N |
O |
||
| GLY | B:254 | B:253 | 75.0 | 1.0 | T | 84.8 | -4.9 | NA | NA | NA | |||||||||||||
| 6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLY | A:254 | A:253 | 73.0 | 0.973 | T | 81.7 | 0.4 | 73.0 | 0.973 | 0.0 |
HOH |
2.982 |
N |
O |
||
| GLY | B:254 | B:253 | 74.0 | 0.987 | T | 88.6 | -4.5 | NA | NA | NA | |||||||||||||
| 6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLY | A:254 | A:253 | 74.0 | 0.987 | T | 82.6 | 0.3 | 74.0 | 0.987 | 0.0 |
HOH |
2.979 |
N |
O |
||
| GLY | B:254 | B:253 | 76.0 | 1.0 | T | 84.7 | -6.4 | NA | NA | NA | |||||||||||||
| 6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLY | A:254 | A:253 | 75.0 | 1.0 | T | 85.6 | -1.7 | 75.0 | 1.0 | 0.0 |
HOH |
2.984 |
N |
O |
||
| GLY | B:254 | B:253 | 76.0 | 1.0 | T | 82.5 | -2.1 | NA | NA | NA | |||||||||||||
| 7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | GLY | A:254 | A:253 | 76.0 | 1.0 | T | 86.3 | -4.1 | 76.0 | 1.0 | 0.0 |
HOH |
2.676 |
O |
O |
||
| GLY | B:254 | B:253 | 75.0 | 1.0 | T | 82.3 | -5.4 | NA | NA | NA | |||||||||||||
| 1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLY | A:253 | A:253 | 74.0 | 0.987 | T | 78.0 | 18.5 | 74.0 | 0.987 | 0.0 |
HOH |
2.786 |
O |
O |
||
| 1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLY | A:253 | A:253 | 77.0 | 1.0 | T | 80.4 | 1.9 | 77.0 | 1.0 | 0.0 |
HOH |
2.722 |
O |
O |
||
| 1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLY | A:253 | A:253 | 75.0 | 1.0 | T | 75.5 | 19.2 | 75.0 | 1.0 | 0.0 |
HOH |
2.804 |
O |
O |
||
| 1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLY | A:253 | A:253 | 77.0 | 1.0 | T | 98.2 | -10.1 | 77.0 | 1.0 | 0.0 |
HOH |
2.804 |
O |
O |
||
| 1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLY | A:253 | A:253 | 77.0 | 1.0 | T | 89.3 | -7.9 | 77.0 | 1.0 | 0.0 |
AUC HOH |
8.666 2.889 |
N O |
C2 O |
||
| 1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLY | A:253 | A:253 | 75.0 | 1.0 | T | 89.5 | -8.8 | 75.0 | 1.0 | 0.0 |
HOH |
2.487 |
N |
O |
||
| 2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | GLY | A:253 | A:253 | 74.0 | 0.987 | T | 88.0 | -7.5 | 74.0 | 0.987 | 0.0 |
HOH |
3.153 |
N |
O |
||
| GLY | B:253 | B:253 | 76.0 | 1.0 | T | 87.2 | -12.5 | NA | NA | NA | |||||||||||||
| 2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | GLY | A:253 | A:253 | 72.0 | 0.96 | T | 98.7 | -8.6 | 72.0 | 0.96 | 0.0 |
HOH |
4.322 |
O |
O |
||
| GLY | B:253 | B:253 | 79.0 | 1.0 | T | 78.4 | -4.1 | NA | NA | NA | |||||||||||||
| 2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | GLY | A:253 | A:253 | 76.0 | 1.0 | T | 84.3 | -11.2 | 76.0 | 1.0 | 0.0 |
HOH |
4.715 |
N |
O |
||
| GLY | B:253 | B:253 | 78.0 | 1.0 | T | 83.6 | -11.4 | NA | NA | NA | |||||||||||||
| 2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | GLY | A:253 | A:253 | 76.0 | 1.0 | T | 83.9 | -6.2 | 76.0 | 1.0 | 0.0 |
HOH |
4.815 |
O |
O |
||
| GLY | B:253 | B:253 | 75.0 | 1.0 | T | 86.8 | -8.3 | NA | NA | NA | |||||||||||||
| 2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | GLY | A:253 | A:253 | 74.0 | 0.987 | T | 83.5 | -25.4 | 74.0 | 0.987 | 0.0 |
HOH |
3.070 |
N |
O |
||
| GLY | B:253 | B:253 | 77.0 | 1.0 | T | 81.3 | -6.5 | NA | NA | NA | |||||||||||||
| 3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | GLY | A:253 | A:253 | 74.0 | 0.987 | T | 92.7 | -22.2 | 74.0 | 0.987 | 0.0 |
HOH |
2.760 |
O |
O |
||
| GLY | B:253 | B:253 | 76.0 | 1.0 | T | 89.1 | -4.5 | NA | NA | NA | |||||||||||||
| 3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | GLY | A:253 | A:253 | 76.0 | 1.0 | T | 80.2 | 0.1 | 76.0 | 1.0 | 0.0 | ||||||
| GLY | B:253 | B:253 | 77.0 | 1.0 | T | 81.0 | -0.1 | NA | NA | NA | |||||||||||||
| 3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | GLY | A:253 | A:253 | 76.0 | 1.0 | T | 75.2 | 0.4 | 76.0 | 1.0 | 0.0 |
HOH |
4.631 |
N |
O |
||
| GLY | B:253 | E:253 | 78.0 | 1.0 | T | 75.7 | -0.1 | NA | NA | NA | |||||||||||||
| 4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | GLY | A:253 | A:253 | 76.0 | 1.0 | T | 78.9 | -4.6 | 76.0 | 1.0 | 0.0 |
HOH |
4.562 |
N |
O |
||
| GLY | B:253 | B:253 | 77.0 | 1.0 | T | 81.4 | -6.1 | NA | NA | NA | |||||||||||||
| 4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | GLY | A:253 | A:253 | 76.0 | 1.0 | T | 82.1 | 3.7 | 76.0 | 1.0 | 0.0 |
HOH |
2.577 |
O |
O |
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| GLY | B:253 | B:253 | 74.0 | 0.987 | T | 90.0 | -1.7 | NA | NA | NA | |||||||||||||
| 4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | GLY | A:253 | A:253 | 75.0 | 1.0 | T | 82.8 | 1.3 | 75.0 | 1.0 | 0.0 |
HOH |
2.937 |
O |
O |
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| GLY | B:253 | B:253 | 79.0 | 1.0 | T | 87.9 | -2.2 | NA | NA | NA | |||||||||||||
| 5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | GLY | A:253 | A:253 | 76.0 | 1.0 | T | 75.9 | 5.7 | 76.0 | 1.0 | 0.0 |
HOH |
2.764 |
N |
O |
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| GLY | B:253 | B:253 | 76.0 | 1.0 | T | 92.5 | -15.4 | NA | NA | NA | |||||||||||||
| 1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | GLY | A:253 | A:253 | 80.0 | 1.0 | T | 87.9 | -14.5 | 80.0 | 1.0 | 0.0 |
HOH |
3.336 |
O |
O |
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| GLY | B:253 | B:253 | 78.0 | 1.0 | S | 82.2 | -3.6 | NA | NA | NA | |||||||||||||
| 1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | GLY | A:253 | A:253 | 78.0 | 1.0 | T | 72.3 | 2.4 | 78.0 | 1.0 | 0.0 |
HOH |
3.116 |
N |
O |
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| GLY | B:253 | B:253 | 76.0 | 1.0 | T | 82.3 | -13.9 | NA | NA | NA | |||||||||||||
| 1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | GLY | A:253 | A:253 | 73.0 | 0.973 | T | 87.3 | 4.6 | 73.0 | 0.973 | 0.0 |
HOH |
3.320 |
N |
O |
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| 2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | GLY | A:253 | A:253 | 78.0 | 1.0 | T | 71.6 | 22.8 | 78.0 | 1.0 | 0.0 | ||||||
| 2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | GLY | A:249 | A:253 | 76.0 | 1.0 | T | 81.3 | 5.1 | 76.0 | 1.0 | 0.0 |
HOH |
3.045 |
N |
O |
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| GLY | B:249 | B:253 | 77.0 | 1.0 | T | 78.9 | -7.1 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | GLY | A:254 | A:254 | 75.0 | 1.0 | T | 78.7 | 0.4 | |